The novel BMI-1 inhibitor PTC596 downregulates MCL-1 and induces p53-independent mitochondrial apoptosis in acute myeloid leukemia progenitor cells
Nishida, Y, Maeda, A, Kim, M J, Cao, L, Kubota, Y, Ishizawa, J, AlRawi, A, Kato, Y, Iwama, A, Fujisawa, M, Matsue, K, Weetall, M, Dumble, M, Andreeff, M, Davis, T W, Branstrom, A, Kimura, S, Kojima, K
Published in Blood cancer journal (New York) (17.02.2017)
Published in Blood cancer journal (New York) (17.02.2017)
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Journal Article
Genetic Basis for Activity Differences between Vancomycin and Glycolipid Derivatives of Vancomycin
Eggert, Ulrike S., Ruiz, Natividad, Falcone, Brian V., Branstrom, Arthur A., Goldman, Robert C., Silhavy, Thomas J., Kahne, Daniel
Published in Science (American Association for the Advancement of Science) (12.10.2001)
Published in Science (American Association for the Advancement of Science) (12.10.2001)
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Journal Article
Phase 1 results of PTC596, a novel small molecule targeting cancer stem cells (CSCs) by reducing levels of BMI1 protein
Shapiro, G, Bedard, P, Infante, J, Bauer, T, Prawira, A, Laksin, O, Weetall, M, Baird, J, Branstrom, A, O'Mara, E, Spiegel, R
Published in European journal of cancer (1990) (01.12.2016)
Published in European journal of cancer (1990) (01.12.2016)
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Journal Article
Antibacterial activity of synthetic analogues based on the disaccharide structure of moenomycin, an inhibitor of bacterial transglycosylase
Baizman, Eugene R, Branstrom, Arthur A, Longley, Clifford B, Allanson, Nigel, Sofia, Michael J, Gange, David, Goldman, Robert C
Published in Microbiology (Society for General Microbiology) (01.12.2000)
Published in Microbiology (Society for General Microbiology) (01.12.2000)
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Journal Article
Chlorobiphenyl-desleucyl-vancomycin inhibits the transglycosylation process required for peptidoglycan synthesis in bacteria in the absence of dipeptide binding
Goldman, Robert C., Baizman, Eugene R., Longley, Clifford B., Branstrom, Arthur A.
Published in FEMS microbiology letters (01.02.2000)
Published in FEMS microbiology letters (01.02.2000)
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Journal Article
PTC124 targets genetic disorders caused by nonsense mutations
Chen, Guangming, Jacobson, Allan, Spatrick, Phyllis, Peltz, Stuart W, Conn, M. Morgan, Friesen, Westley J, Almstead, Neil G, Hedrick, Jean, Campbell, Jeffrey A, Mollin, Anna, Kawana, Masataka, Wilde, Richard G, Yeh, Shirley, Sweeney, H. Lee, Trotta, Christopher R, Khan, Atiyya, Welch, Ellen M, Barton, Elisabeth R, Hirawat, Samit, Turpoff, Anthony A, Weetall, Marla, Ren, Hongyu, Risher, Nicole, Tomizawa, Yuki, Northcutt, Valerie J, Miller, Langdon L, He, Feng, Jones, Stephen, Colacino, Joseph M, Feng, Huisheng, Branstrom, Arthur A, Corson, Donald, Zhuo, Jin, Ju, William D, Patel, Meenal, Moon, Young-Choon, Hwang, Seongwoo, Paushkin, Sergey, Babiak, John, Trifillis, Panayiota, Karp, Gary, Takasugi, James
Published in Nature (03.05.2007)
Published in Nature (03.05.2007)
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Attenuated bacteria as a DNA delivery vehicle for DNA-mediated immunization
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Conference Proceeding
Synthesis and Mode of Action of Hydrophobic Derivatives of the Glycopeptide Antibiotic Eremomycin and Des-(N-methyl-d-leucyl)eremomycin against Glycopeptide-Sensitive and -Resistant Bacteria
Printsevskaya, Svetlana S, Pavlov, Andrey Y, Olsufyeva, Evgenia N, Mirchink, Elena P, Isakova, Elena B, Reznikova, Marina I, Goldman, Robert C, Branstrom, Arthur A, Baizman, Eugene R, Longley, Clifford B, Sztaricskai, Ferenc, Batta, Gyula, Preobrazhenskaya, Maria N
Published in Journal of medicinal chemistry (14.03.2002)
Published in Journal of medicinal chemistry (14.03.2002)
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Discovery and Optimization of Indolyl-Containing 4‑Hydroxy-2-Pyridone Type II DNA Topoisomerase Inhibitors Active against Multidrug Resistant Gram-negative Bacteria
Gerasyuto, Aleksey I, Arnold, Michael A, Wang, Jiashi, Chen, Guangming, Zhang, Xiaoyan, Smith, Sean, Woll, Matthew G, Baird, John, Zhang, Nanjing, Almstead, Neil G, Narasimhan, Jana, Peddi, Srinivasa, Dumble, Melissa, Sheedy, Josephine, Weetall, Marla, Branstrom, Arthur A, Prasad, J. V. N, Karp, Gary M
Published in Journal of medicinal chemistry (24.05.2018)
Published in Journal of medicinal chemistry (24.05.2018)
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Journal Article
Synthesis of Hydrophobic N'-Mono and N', N′′-Double Alkylated Eremomycins Inhibiting the Transglycosylation Stage of Bacterial Cell Wall Biosynthesis
PAVLOV, A. Y., MIROSHNIKOVA, O. V, PRINTSEVSKAYA, S. S., OLSUFYEVA, E. N., PREOBRAZHENSKAYA, M. N., GOLDMAN, R. C., BRANSTROM, A. A., BAIZMAN, E. R., LONGLEY, C. B.
Published in Journal of antibiotics (2001)
Published in Journal of antibiotics (2001)
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Journal Article
4-Hydroxy-2-pyridones: Discovery and evaluation of a novel class of antibacterial agents targeting DNA synthesis
Arnold, Michael A., Gerasyuto, Aleksey I., Wang, Jiashi, Du, Wu, Gorske, Yi Jin Kim, Arasu, Tamil, Baird, John, Almstead, Neil G., Narasimhan, Jana, Peddi, Srinivasa, Ginzburg, Olya, Lue, Stanley W., Hedrick, Jean, Sheedy, Josephine, Lagaud, Guy, Branstrom, Arthur A., Weetall, Marla, Prasad, J.V.N. Vara, Karp, Gary M.
Published in Bioorganic & medicinal chemistry letters (15.11.2017)
Published in Bioorganic & medicinal chemistry letters (15.11.2017)
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Journal Article
Correction to Discovery and Optimization of Indolyl-Containing 4‑Hydroxy-2-pyridone Type II DNA Topoisomerase Inhibitors Active against Multidrug Resistant Gram-Negative Bacteria
Gerasyuto, Aleksey I, Arnold, Michael A, Wang, Jiashi, Chen, Guangming, Zhang, Xiaoyan, Smith, Sean, Woll, Matthew G, Baird, John, Zhang, Nanjing, Almstead, Neil G, Narasimhan, Jana, Peddi, Srinivasa, Dumble, Melissa, Sheedy, Josephine, Weetall, Marla, Branstrom, Arthur A, Prasad, J. V. N, Karp, Gary M
Published in Journal of medicinal chemistry (25.10.2018)
Published in Journal of medicinal chemistry (25.10.2018)
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Journal Article
In situ assay for identifying inhibitors of bacterial transglycosylase
Branstrom, Arthur A, Midha, Sunita, Goldman, Robert C
Published in FEMS microbiology letters (15.10.2000)
Published in FEMS microbiology letters (15.10.2000)
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Journal Article
Synthesis and biological evaluation of analogues of bacterial lipid I
SILVA, Domingos J, BOWE, Caryn L, BRANSTROM, Arthur A, BAIZMAN, Eugene R, SOFIA, Michael J
Published in Bioorganic & medicinal chemistry letters (18.12.2000)
Published in Bioorganic & medicinal chemistry letters (18.12.2000)
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Journal Article
Interaction of Salmonella typhi strains with cultured human monocyte-derived macrophages
SIZEMORE, D. R, ELSINGHORST, E. A, ECK, L. C, BRANSTROM, A. A, HOOVER, D. L, WARREN, R. L, RUBIN, F. A
Published in Infection and Immunity (01.01.1997)
Published in Infection and Immunity (01.01.1997)
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Journal Article
452 - Phase 1 results of PTC596, a novel small molecule targeting cancer stem cells (CSCs) by reducing levels of BMI1 protein
Shapiro, G., Bedard, P., Infante, J., Bauer, T., Prawira, A., Laksin, O., Weetall, M., Baird, J., Branstrom, A., O'Mara, E., Spiegel, R.
Published in European journal of cancer (1990) (01.12.2016)
Published in European journal of cancer (1990) (01.12.2016)
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