Structural Requirements of Transmembrane Domain 3 for Activation by the M1 Muscarinic Receptor Agonists AC-42, AC-260584, Clozapine, and N-Desmethylclozapine: Evidence for Three Distinct Modes of Receptor Activation
Spalding, Tracy A, Ma, Jian-Nong, Ott, Thomas R, Friberg, Mikael, Bajpai, Abhishek, Bradley, Stefania Risso, Davis, Robert E, Brann, Mark R, Burstein, Ethan S
Published in Molecular pharmacology (01.12.2006)
Published in Molecular pharmacology (01.12.2006)
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ACP-103, a 5-Hydroxytryptamine 2A Receptor Inverse Agonist, Improves the Antipsychotic Efficacy and Side-Effect Profile of Haloperidol and Risperidone in Experimental Models
Gardell, Luis R, Vanover, Kimberly E, Pounds, Linda, Johnson, Robert W, Barido, Richard, Anderson, Gary T, Veinbergs, Isaac, Dyssegaard, Agnete, Brunmark, Per, Tabatabaei, Ali, Davis, Robert E, Brann, Mark R, Hacksell, Uli, Bonhaus, Douglas W
Published in The Journal of pharmacology and experimental therapeutics (01.08.2007)
Published in The Journal of pharmacology and experimental therapeutics (01.08.2007)
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Characterization of the Mas‐related gene family: structural and functional conservation of human and rhesus MrgX receptors
Burstein, Ethan S, Ott, Thomas R, Feddock, Michele, Ma, Jian‐Nong, Fuhs, Steve, Wong, Steven, Schiffer, Hans H, Brann, Mark R, Nash, Norman R
Published in British journal of pharmacology (01.01.2006)
Published in British journal of pharmacology (01.01.2006)
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Broad modulation of neuropathic pain states by a selective estrogen receptor beta agonist
Piu, Fabrice, Cheevers, Cindy, Hyldtoft, Lene, Gardell, Luis R., Del Tredici, Andria L., Andersen, Carsten B., Fairbairn, Luke C., Lund, Birgitte W., Gustafsson, Magnus, Schiffer, Hans H., Donello, John E., Olsson, Roger, Gil, Daniel W., Brann, Mark R.
Published in European journal of pharmacology (20.08.2008)
Published in European journal of pharmacology (20.08.2008)
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Discovery of a Potent, Orally Available, and Isoform-Selective Retinoic Acid β2 Receptor Agonist
Lund, Birgitte W, Piu, Fabrice, Gauthier, Natalie K, Eeg, Anne, Currier, Erika, Sherbukhin, Vladimir, Brann, Mark R, Hacksell, Uli, Olsson, Roger
Published in Journal of medicinal chemistry (01.12.2005)
Published in Journal of medicinal chemistry (01.12.2005)
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Constitutively Active Mutants of the Histamine H1 Receptor Suggest a Conserved Hydrophobic Asparagine-Cage That Constrains the Activation of Class A G Protein-Coupled Receptors
Bakker, Remko A, Jongejan, Aldo, Sansuk, Kamonchanok, Hacksell, Uli, Timmerman, Henk, Brann, Mark R, Weiner, Dave M, Pardo, Leonardo, Leurs, Rob
Published in Molecular pharmacology (01.01.2008)
Published in Molecular pharmacology (01.01.2008)
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Identification of novel subtype selective RAR agonists
Piu, Fabrice, Gauthier, Natalie K., Olsson, Roger, Currier, Erika A., Lund, Birgitte W., Croston, Glenn E., Hacksell, Uli, Brann, Mark R.
Published in Biochemical pharmacology (19.12.2005)
Published in Biochemical pharmacology (19.12.2005)
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Monitoring Interactions between Receptor Tyrosine Kinases and Their Downstream Effector Proteins in Living Cells Using Bioluminescence Resonance Energy Transfer
Tan, Philip K, Wang, Jean, Littler, Pey-Lih H, Wong, Kenneth K, Sweetnam, Timothy A, Keefe, William, Nash, Norman R, Reding, Esther C, Piu, Fabrice, Brann, Mark R, Schiffer, Hans H
Published in Molecular pharmacology (01.12.2007)
Published in Molecular pharmacology (01.12.2007)
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Journal Article
Pharmacology and Signaling Properties of Epidermal Growth Factor Receptor Isoforms Studied by Bioluminescence Resonance Energy Transfer
Schiffer, Hans H, Reding, Esther C, Fuhs, Stephen R, Lu, Qing, Piu, Fabrice, Wong, Steven, Littler, Pey-Lih H, Weiner, Dave M, Keefe, William, Tan, Phil K, Nash, Norman R, Knapp, Anne E, Olsson, Roger, Brann, Mark R
Published in Molecular pharmacology (01.02.2007)
Published in Molecular pharmacology (01.02.2007)
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Journal Article
Identification of the Atypical L-Type Ca2+ Channel Blocker Diltiazem and Its Metabolites As Ghrelin Receptor Agonists
Ma, Jian-Nong, Schiffer, Hans H, Knapp, Anne E, Wang, Jean, Wong, Kenneth K, Currier, Erika A, Owens, Michelle, Nash, Norman R, Gardell, Luis R, Brann, Mark R, Olsson, Roger, Burstein, Ethan S
Published in Molecular pharmacology (01.08.2007)
Published in Molecular pharmacology (01.08.2007)
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Loss-of-Function Polymorphic Variants of the Human Angiotensin II Type 1 Receptor
Hansen, Jakob Lerche, Haunsø, Stig, Brann, Mark R, Sheikh, Søren P, Weiner, David M
Published in Molecular pharmacology (01.03.2004)
Published in Molecular pharmacology (01.03.2004)
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Journal Article
Pharmacological Characterization of AC-90179 [2-(4-Methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)-acetamide Hydrochloride]: A Selective Serotonin 2A Receptor Inverse Agonist
Vanover, Kimberly E, Harvey, Scott C, Son, Thomas, Bradley, Stefania Risso, Kold, Henriette, Makhay, Malath, Veinbergs, Isaac, Spalding, Tracy A, Weiner, David M, Andersson, Carl Magnus, Tolf, Bo-Ragnar, Brann, Mark R, Hacksell, Uli, Davis, Robert E
Published in The Journal of pharmacology and experimental therapeutics (01.09.2004)
Published in The Journal of pharmacology and experimental therapeutics (01.09.2004)
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Journal Article
Differential modulation of inflammatory pain by a selective estrogen receptor beta agonist
Gardell, Luis R., Hyldtoft, Lene, Del Tredici, Andria L., Andersen, Carsten B., Fairbairn, Luke C., Lund, Birgitte W., Gustafsson, Magnus, Brann, Mark R., Olsson, Roger, Piu, Fabrice
Published in European journal of pharmacology (11.09.2008)
Published in European journal of pharmacology (11.09.2008)
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Journal Article
PET analysis of the 5-HT2A receptor inverse agonist ACP-103 in human brain
Nordstrom, Anna-Lena, Mansson, Mattias, Jovanovic, Hristina, Karlsson, Per, Halldin, Christer, Farde, Lars, Vanover, Kimberly E., Hacksell, Uli, Brann, Mark R., Davis, Robert E., Weiner, David M.
Published in The international journal of neuropsychopharmacology (01.03.2008)
Published in The international journal of neuropsychopharmacology (01.03.2008)
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Integrative Functional Assays, Chemical Genomics and High Throughput Screening: Harnessing Signal Transduction Pathways to a Common HTS Readout
Burstein, Ethan S, Piu, Fabrice, Ma, Jian-Nong, Weissman, Jacques T, Currier, Erika A, Nash, Norman R, Weiner, David M, Spalding, Tracy A, Schiffer, Hans H, Del Tredici, Andria L, Brann, Mark R
Published in Current pharmaceutical design (01.05.2006)
Published in Current pharmaceutical design (01.05.2006)
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Discovery of the First Nonpeptide Agonist of the GPR14/Urotensin-II Receptor: 3-(4-Chlorophenyl)-3-(2- (dimethylamino)ethyl)isochroman-1-one (AC-7954)
Croston, Glenn E, Olsson, Roger, Currier, Erika A, Burstein, Ethan S, Weiner, David, Nash, Norman, Severance, Daniel, Allenmark, Stig G, Thunberg, Linda, Ma, Jian-Nong, Mohell, Nina, O'Dowd, Brian, Brann, Mark R, Hacksell, Uli
Published in Journal of medicinal chemistry (07.11.2002)
Published in Journal of medicinal chemistry (07.11.2002)
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Journal Article
Identification of novel selective v2 receptor non-peptide agonists
DEL TREDID, Andria L, VANOVER, Kim E, MOHELL, Nina, OLSSON, Roger, PIN, Fabrice, KNAPP, Anne E, BERTOZZI, Sine M, NASH, Norman R, BURSTEIN, Ethan S, LAMEH, Jelveh, CURRIER, Erika A, DAVIS, Robert E, BRANN, Mark R
Published in Biochemical pharmacology (30.10.2008)
Published in Biochemical pharmacology (30.10.2008)
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