Defining critical residues for substrate binding to 1‐deoxy‐d‐xylulose 5‐phosphate synthase – active site substitutions stabilize the predecarboxylation intermediate C2α‐lactylthiamin diphosphate
Brammer Basta, Leighanne A., Patel, Hetalben, Kakalis, Lazaros, Jordan, Frank, Freel Meyers, Caren L.
Published in The FEBS journal (01.06.2014)
Published in The FEBS journal (01.06.2014)
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Structural insight into the inactivation of Mycobacterium tuberculosis non-classical transpeptidase LdtMt2 by biapenem and tebipenem
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Published in BMC biochemistry (25.05.2017)
Published in BMC biochemistry (25.05.2017)
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Atypically Modified Carbapenem Antibiotics Display Improved Antimycobacterial Activity in the Absence of β‑Lactamase Inhibitors
Gupta, Rashmi, Al-Kharji, Noora M. S. A, Alqurafi, Maha A, Nguyen, Thu Q, Chai, Weirui, Quan, Pojun, Malhotra, Riya, Simcox, Breven S, Mortimer, Phil, Brammer Basta, Leighanne A, Rohde, Kyle H, Buynak, John D
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Published in ACS infectious diseases (13.08.2021)
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Phylogenetic and Biochemical Analyses of Mycobacterial l,d-Transpeptidases Reveal a Distinct Enzyme Class That Is Preferentially Acylated by Meropenem
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Published in ACS infectious diseases (13.12.2019)
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Loss of a Functionally and Structurally Distinct ld-Transpeptidase, LdtMt5, Compromises Cell Wall Integrity in Mycobacterium tuberculosis
Brammer Basta, Leighanne A., Ghosh, Anita, Pan, Ying, Jakoncic, Jean, Lloyd, Evan P., Townsend, Craig A., Lamichhane, Gyanu, Bianchet, Mario A.
Published in The Journal of biological chemistry (16.10.2015)
Published in The Journal of biological chemistry (16.10.2015)
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Efficient synthesis for each of the eight stereoisomers of the iminosugars lentiginosine and 1,4-dideoxy-1,4-imino-D-arabinitol (DAB)
Liotta, Louis J., Antoine, Jessica, Brammer Basta, Leighanne A., Campbell, Andrew S., Cole, Gabrielle Y., Demick Brazile, Kristen A., Dogal Gardner, Natalie M., Fitzgerald, Megan E., Francois, Jean E.K., French, Brian M., Garafola, Sara L., Giannetti, Catherine A., Granatosky, Eve A., Harney, Alycen M., Hummel, James T., Joyce, Andrew P., Keylor, Mitchell H., Khubchandani, Jasmine A., Korzeniecki, Claudia, Lieberman, Diana C., Litterio, Joshua M., Maiorano, Madison O., Marshall, Jessica F., McCarthy, Kelly A., Mendes Vieira, Andreia, Miller, Ruby M., Morrison, Emily R., Moura, Steven P., Neumann, Dillon F., Oliveira, Aliza F., Pace, Nicholas J., Plouffe, Jodie X., Pomfret, Meredith N., Reardon, Katelyn N., Sheller-Miller, Samantha M., Smith, Michael J., Sullivan, Jessica L., Sweeney, Samantha W., Tougas, Kerstin L.
Published in Carbohydrate research (01.11.2024)
Published in Carbohydrate research (01.11.2024)
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Manipulating the 3D organization of the largest synthetic yeast chromosome
Zhang, Weimin, Lazar-Stefanita, Luciana, Yamashita, Hitoyoshi, Shen, Michael J, Mitchell, Leslie A, Kurasawa, Hikaru, Lobzaev, Evgenii, Fanfani, Viola, Haase, Max A B, Sun, Xiaoji, Jiang, Qingwen, Goldberg, Gregory W, Ichikawa, David M, Lauer, Stephanie L, McCulloch, Laura H, Easo, Nicole, Lin, S Jiaming, Camellato, Brendan R, Zhu, Yinan, Cai, Jitong, Xu, Zhuwei, Zhao, Yu, Sacasa, Maya, Noyes, Marcus B, Bader, Joel S, Deutsch, Samuel, Stracquadanio, Giovanni, Aizawa, Yasunori, Dai, Junbiao, Boeke, Jef D
Published in Molecular cell (07.12.2023)
Published in Molecular cell (07.12.2023)
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Defining critical residues for substrate binding to 1-deoxy-d-xylulose 5-phosphate synthase - active site substitutions stabilize the predecarboxylation intermediate C2[alpha]-lactylthiamin diphosphate
Brammer Basta, Leighanne A, Patel, Hetalben, Kakalis, Lazaros, Jordan, Frank, Freel Meyers, Caren L
Published in The FEBS journal (01.06.2014)
Published in The FEBS journal (01.06.2014)
Get full text
Journal Article
Defining critical residues for substrate binding to 1-deoxy-d-xylulose 5-phosphate synthase: Active site substitutions stabilize the pre-decarboxylation intermediate C2α-lactylthiamin diphosphate
Basta, Leighanne A. Brammer, Patel, Hetalben, Kakalis, Lazaros, Jordan, Frank, Meyers, Caren L. Freel
Published in The FEBS journal (12.05.2014)
Published in The FEBS journal (12.05.2014)
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Journal Article
Loss of a Functionally and Structurally Distinct ld-Transpeptidase, Ldt Mt5 , Compromises Cell Wall Integrity in Mycobacterium tuberculosis
Brammer Basta, Leighanne A., Ghosh, Anita, Pan, Ying, Jakoncic, Jean, Lloyd, Evan P., Townsend, Craig A., Lamichhane, Gyanu, Bianchet, Mario A.
Published in The Journal of biological chemistry (24.08.2015)
Published in The Journal of biological chemistry (24.08.2015)
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Journal Article
Structural insight into the inactivation of Mycobacterium tuberculosis non-classical transpeptidase Ldt Mt2 by biapenem and tebipenem
Bianchet, Mario A, Pan, Ying H, Basta, Leighanne A Brammer, Saavedra, Harry, Lloyd, Evan P, Kumar, Pankaj, Mattoo, Rohini, Townsend, Craig A, Lamichhane, Gyanu
Published in BMC biochemistry (25.05.2017)
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Published in BMC biochemistry (25.05.2017)
Journal Article
Manipulating the 3D organization of the largest synthetic yeast chromosome
Zhang, Weimin, Luciana Lazar Stefanita, Yamashita, Hitoyoshi, Shen, Michael J, Mitchell, Leslie A, Kurasawa, Hikaru, Haase, Max A B, Sun, Xiaoji, Jiang, Qingwen, Lauer, Stephanie L, Mcculloch, Laura H, Zhao, Yu, Ichikawa, David, Easo, Nicole, S Jiaming Lin, Fanfani, Viola, Camellato, Brendan R, Zhu, Yinan, Cai, Jitong, Xu, Zhuwei, Sacasa, Maya, Accardo, Ryan, Ju Young Ahn, Annadanam, Surekha, Leighanne A Brammer Basta, Bello, Nicholas, Cai, Lousanna, Cerritos, Stephanie, Macintosh Cornwell, D'amato, Anthony, Hacker, Maria, Hersey, Kenneth, Kennedy, Emma, Kianercy, Ardeshir, Kim, Dohee, Hong Seo Lim, Mccutcheon, Griffin, Mcgirr, Kimiko, Meaney, Nora, Meyer, Lauren, Moyer, Ally, Nimer, Maisa, Sabbatini, Carla, Scheifele, Lisa, Shores, Lucas, Silvestrone, Cassandra, Snee, Arden, Spina, Antonio, Staiti, Anthony, Stuver, Matt, Tian, Elli, Whearty, Danielle, Zhao, Calvin, Zheng, Tony, Zhou, Vivian, Zeller, Karen, Bader, Joel S, Stracquadanio, Giovanni, Deutsch, Samuel, Dai, Junbiao, Aizawa, Yasunori, Boeke, Jef D
Published in bioRxiv (10.04.2022)
Published in bioRxiv (10.04.2022)
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