Population-Scale CT-based Body Composition Analysis of a Large Outpatient Population Using Deep Learning to Derive Age-, Sex-, and Race-specific Reference Curves
Magudia, Kirti, Bridge, Christopher P, Bay, Camden P, Babic, Ana, Fintelmann, Florian J, Troschel, Fabian M, Miskin, Nityanand, Wrobel, William C, Brais, Lauren K, Andriole, Katherine P, Wolpin, Brian M, Rosenthal, Michael H
Published in Radiology (01.02.2021)
Published in Radiology (01.02.2021)
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Management of Neuroendocrine Tumor Liver Metastases: Long-Term Outcomes and Prognostic Factors from a Large Prospective Database
Fairweather, Mark, Swanson, Richard, Wang, Jiping, Brais, Lauren K., Dutton, Trevor, Kulke, Matthew H., Clancy, Thomas E.
Published in Annals of surgical oncology (01.08.2017)
Published in Annals of surgical oncology (01.08.2017)
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Cancer Susceptibility Gene Mutations in Individuals With Colorectal Cancer
Yurgelun, Matthew B, Kulke, Matthew H, Fuchs, Charles S, Allen, Brian A, Uno, Hajime, Hornick, Jason L, Ukaegbu, Chinedu I, Brais, Lauren K, McNamara, Philip G, Mayer, Robert J, Schrag, Deborah, Meyerhardt, Jeffrey A, Ng, Kimmie, Kidd, John, Singh, Nanda, Hartman, Anne-Renee, Wenstrup, Richard J, Syngal, Sapna
Published in Journal of clinical oncology (01.04.2017)
Published in Journal of clinical oncology (01.04.2017)
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Lead-Time Trajectory of CA19-9 as an Anchor Marker for Pancreatic Cancer Early Detection
Fahrmann, Johannes F., Schmidt, C. Max, Mao, Xiangying, Irajizad, Ehsan, Loftus, Maureen, Zhang, Jinming, Patel, Nikul, Vykoukal, Jody, Dennison, Jennifer B., Long, James P., Do, Kim-Anh, Zhang, Jianjun, Chabot, John A., Kluger, Michael D., Kastrinos, Fay, Brais, Lauren, Babic, Ana, Jajoo, Kunal, Lee, Linda S., Clancy, Thomas E., Ng, Kimmie, Bullock, Andrea, Genkinger, Jeanine, Yip-Schneider, Michele T., Maitra, Anirban, Wolpin, Brian M., Hanash, Samir
Published in Gastroenterology (New York, N.Y. 1943) (01.03.2021)
Published in Gastroenterology (New York, N.Y. 1943) (01.03.2021)
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Composition, Spatial Characteristics, and Prognostic Significance of Myeloid Cell Infiltration in Pancreatic Cancer
Väyrynen, Sara A, Zhang, Jinming, Yuan, Chen, Väyrynen, Juha P, Dias Costa, Andressa, Williams, Hannah, Morales-Oyarvide, Vicente, Lau, Mai Chan, Rubinson, Douglas A, Dunne, Richard F, Kozak, Margaret M, Wang, Wenjia, Agostini-Vulaj, Diana, Drage, Michael G, Brais, Lauren, Reilly, Emma, Rahma, Osama, Clancy, Thomas, Wang, Jiping, Linehan, David C, Aguirre, Andrew J, Fuchs, Charles S, Coussens, Lisa M, Chang, Daniel T, Koong, Albert C, Hezel, Aram F, Ogino, Shuji, Nowak, Jonathan A, Wolpin, Brian M
Published in Clinical cancer research (15.02.2021)
Published in Clinical cancer research (15.02.2021)
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Diabetes, Weight Change, and Pancreatic Cancer Risk
Yuan, Chen, Babic, Ana, Khalaf, Natalia, Nowak, Jonathan A, Brais, Lauren K, Rubinson, Douglas A, Ng, Kimmie, Aguirre, Andrew J, Pandharipande, Pari V, Fuchs, Charles S, Giovannucci, Edward L, Stampfer, Meir J, Rosenthal, Michael H, Sander, Chris, Kraft, Peter, Wolpin, Brian M
Published in JAMA oncology (01.10.2020)
Published in JAMA oncology (01.10.2020)
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Germline cancer susceptibility gene variants, somatic second hits, and survival outcomes in patients with resected pancreatic cancer
Yurgelun, Matthew B., Chittenden, Anu B., Morales-Oyarvide, Vicente, Rubinson, Douglas A., Dunne, Richard F., Kozak, Margaret M., Qian, Zhi Rong, Welch, Marisa W., Brais, Lauren K., Da Silva, Annacarolina, Bui, Justin L., Yuan, Chen, Li, Tingting, Li, Wanwan, Masuda, Atsuhiro, Gu, Mancang, Bullock, Andrea J., Chang, Daniel T., Clancy, Thomas E., Linehan, David C., Findeis-Hosey, Jennifer J., Doyle, Leona A., Thorner, Aaron R., Ducar, Matthew D., Wollison, Bruce M., Khalaf, Natalia, Perez, Kimberly, Syngal, Sapna, Aguirre, Andrew J., Hahn, William C., Meyerson, Matthew L., Fuchs, Charles S., Ogino, Shuji, Hornick, Jason L., Hezel, Aram F., Koong, Albert C., Nowak, Jonathan A., Wolpin, Brian M.
Published in Genetics in medicine (01.01.2019)
Published in Genetics in medicine (01.01.2019)
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A Transcriptome-Wide Association Study Identifies Novel Candidate Susceptibility Genes for Pancreatic Cancer
Zhong, Jun, Jermusyk, Ashley, Wu, Lang, Hoskins, Jason W, Collins, Irene, Mocci, Evelina, Zhang, Mingfeng, Song, Lei, Chung, Charles C, Zhang, Tongwu, Xiao, Wenming, Albanes, Demetrius, Andreotti, Gabriella, Arslan, Alan A, Babic, Ana, Bamlet, William R, Beane-Freeman, Laura, Berndt, Sonja, Borgida, Ayelet, Bracci, Paige M, Brais, Lauren, Brennan, Paul, Bueno-de-Mesquita, Bas, Buring, Julie, Canzian, Federico, Childs, Erica J, Cotterchio, Michelle, Du, Mengmeng, Duell, Eric J, Fuchs, Charles, Gallinger, Steven, Gaziano, J Michael, Giles, Graham G, Giovannucci, Edward, Goggins, Michael, Goodman, Gary E, Goodman, Phyllis J, Haiman, Christopher, Hartge, Patricia, Hasan, Manal, Helzlsouer, Kathy J, Holly, Elizabeth A, Klein, Eric A, Kogevinas, Manolis, Kurtz, Robert J, LeMarchand, Loic, Malats, Núria, Männistö, Satu, Milne, Roger, Neale, Rachel E, Ng, Kimmie, Obazee, Ofure, Oberg, Ann L, Orlow, Irene, Patel, Alpa V, Peters, Ulrike, Porta, Miquel, Rothman, Nathaniel, Scelo, Ghislaine, Sesso, Howard D, Severi, Gianluca, Sieri, Sabina, Silverman, Debra, Sund, Malin, Tjønneland, Anne, Thornquist, Mark D, Tobias, Geoffrey S, Trichopoulou, Antonia, Van Den Eeden, Stephen K, Visvanathan, Kala, Wactawski-Wende, Jean, Wentzensen, Nicolas, White, Emily, Yu, Herbert, Yuan, Chen, Zeleniuch-Jacquotte, Anne, Hoover, Robert, Brown, Kevin, Kooperberg, Charles, Risch, Harvey A, Jacobs, Eric J, Li, Donghui, Yu, Kai, Shu, Xiao-Ou, Chanock, Stephen J, Wolpin, Brian M, Stolzenberg-Solomon, Rachael Z, Chatterjee, Nilanjan, Klein, Alison P, Smith, Jill P, Kraft, Peter, Shi, Jianxin, Petersen, Gloria M, Zheng, Wei, Amundadottir, Laufey T
Published in JNCI : Journal of the National Cancer Institute (01.10.2020)
Published in JNCI : Journal of the National Cancer Institute (01.10.2020)
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Adipose tissue and skeletal muscle wasting precede clinical diagnosis of pancreatic cancer
Babic, Ana, Rosenthal, Michael H., Sundaresan, Tilak K., Khalaf, Natalia, Lee, Valerie, Brais, Lauren K., Loftus, Maureen, Caplan, Leah, Denning, Sarah, Gurung, Anamol, Harrod, Joanna, Schawkat, Khoschy, Yuan, Chen, Wang, Qiao-Li, Lee, Alice A., Biller, Leah H., Yurgelun, Matthew B., Ng, Kimmie, Nowak, Jonathan A., Aguirre, Andrew J., Bhatia, Sangeeta N., Vander Heiden, Matthew G., Van Den Eeden, Stephen K., Caan, Bette J., Wolpin, Brian M.
Published in Nature communications (18.07.2023)
Published in Nature communications (18.07.2023)
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Altered exocrine function can drive adipose wasting in early pancreatic cancer
Danai, Laura V., Babic, Ana, Rosenthal, Michael H., Dennstedt, Emily A., Muir, Alexander, Lien, Evan C., Mayers, Jared R., Tai, Karen, Lau, Allison N., Jones-Sali, Paul, Prado, Carla M., Petersen, Gloria M., Takahashi, Naoki, Sugimoto, Motokazu, Yeh, Jen Jen, Lopez, Nicole, Bardeesy, Nabeel, Fernandez-del Castillo, Carlos, Liss, Andrew S., Koong, Albert C., Bui, Justin, Yuan, Chen, Welch, Marisa W., Brais, Lauren K., Kulke, Matthew H., Dennis, Courtney, Clish, Clary B., Wolpin, Brian M., Vander Heiden, Matthew G.
Published in Nature (London) (01.06.2018)
Published in Nature (London) (01.06.2018)
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Trifluridine/Tipiracil and Regorafenib in Patients with Metastatic Colorectal Cancer: A Retrospective Study at a Tertiary Oncology Center
Patel, Anuj K., Abhyankar, Ritika, Brais, Lauren K., Duh, Mei Sheng, Barghout, Victoria E., Huynh, Lynn, Yenikomshian, Mihran A., Ng, Kimmie, Fuchs, Charles S.
Published in The oncologist (Dayton, Ohio) (01.12.2021)
Published in The oncologist (Dayton, Ohio) (01.12.2021)
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Utility of Normalized Body Composition Areas, Derived From Outpatient Abdominal CT Using a Fully Automated Deep Learning Method, for Predicting Subsequent Cardiovascular Events
Magudia, Kirti, Bridge, Christopher P, Bay, Camden P, Farah, Subrina, Babic, Ana, Fintelmann, Florian J, Brais, Lauren K, Andriole, Katherine P, Wolpin, Brian M, Rosenthal, Michael H
Published in American journal of roentgenology (1976) (01.02.2023)
Published in American journal of roentgenology (1976) (01.02.2023)
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Drug-related pneumonitis during mammalian target of rapamycin inhibitor therapy in patients with neuroendocrine tumors: a radiographic pattern-based approach
Nishino, Mizuki, Brais, Lauren K, Brooks, Nichole V, Hatabu, Hiroto, Kulke, Matthew H, Ramaiya, Nikhil H
Published in European journal of cancer (1990) (01.01.2016)
Published in European journal of cancer (1990) (01.01.2016)
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Association Between Somatostatin Receptor Expression and Clinical Outcomes in Neuroendocrine Tumors
Qian, Zhi Rong, Li, Tingting, Ter-Minassian, Monica, Yang, Juhong, Chan, Jennifer A, Brais, Lauren K, Masugi, Yohei, Thiaglingam, Arunthathi, Brooks, Nichole, Nishihara, Reiko, Bonnemarie, Mireille, Masuda, Atsuhiro, Inamura, Kentaro, Kim, Sun A, Mima, Kosuke, Sukawa, Yasutaka, Dou, Ruoxu, Lin, Xihong, Christiani, David C, Schmidlin, Fabien, Fuchs, Charles S, Mahmood, Umar, Ogino, Shuji, Kulke, Matthew H
Published in Pancreas (01.11.2016)
Published in Pancreas (01.11.2016)
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Characterization of the Neuroendocrine Tumor Immune Microenvironment
da Silva, Annacarolina, Bowden, Michaela, Zhang, Sui, Masugi, Yohei, Thorner, Aaron R, Herbert, Zachary T, Zhou, Chensheng Willa, Brais, Lauren, Chan, Jennifer A, Hodi, F Stephen, Rodig, Scott, Ogino, Shuji, Kulke, Matthew H
Published in Pancreas (01.10.2018)
Published in Pancreas (01.10.2018)
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Clinical outcomes and ctDNA correlates for CAPOX BETR: a phase II trial of capecitabine, oxaliplatin, bevacizumab, trastuzumab in previously untreated advanced HER2+ gastroesophageal adenocarcinoma
Singh, Harshabad, Lowder, Kristen E., Kapner, Kevin, Kelly, Ronan J., Zheng, Hui, McCleary, Nadine Jackson, Abrams, Thomas A., Chan, Jennifer A., Regan, Eileen M., Klempner, Samuel J., Hannigan, Alison M., Remland, Joshua, Brais, Lauren K., Andrews, Elizabeth, Yurgelun, Matthew, Cleary, James M., Rubinson, Douglas A., Ritterhouse, Lauren L., Maron, Garrett, Aguirre, Andrew J., Meyerhardt, Jeffrey A., Gardecki, Emma, Lennerz, Jochen K., Wolpin, Brian M., Enzinger, Peter C.
Published in Nature communications (09.08.2024)
Published in Nature communications (09.08.2024)
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Oncogenic Drivers and Therapeutic Vulnerabilities in KRAS Wild-Type Pancreatic Cancer
Singh, Harshabad, Keller, Rachel B, Kapner, Kevin S, Dilly, Julien, Raghavan, Srivatsan, Yuan, Chen, Cohen, Elizabeth F, Tolstorukov, Michael, Andrews, Elizabeth, Brais, Lauren K, da Silva, Annacarolina, Perez, Kimberly, Rubinson, Douglas A, Surana, Rishi, Giannakis, Marios, Ng, Kimmie, Clancy, Thomas E, Yurgelun, Matthew B, Schlechter, Benjamin L, Clark, Jeffrey W, Shapiro, Geoffrey I, Rosenthal, Michael H, Hornick, Jason L, Nardi, Valentina, Li, Yvonne Y, Gupta, Hersh, Cherniack, Andrew D, Meyerson, Matthew, Cleary, James M, Nowak, Jonathan A, Wolpin, Brian M, Aguirre, Andrew J
Published in Clinical cancer research (14.11.2023)
Published in Clinical cancer research (14.11.2023)
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Spatially Resolved Single-Cell Assessment of Pancreatic Cancer Expression Subtypes Reveals Co-expressor Phenotypes and Extensive Intratumoral Heterogeneity
Williams, Hannah L, Dias Costa, Andressa, Zhang, Jinming, Raghavan, Srivatsan, Winter, Peter S, Kapner, Kevin S, Ginebaugh, Scott P, Väyrynen, Sara A, Väyrynen, Juha P, Yuan, Chen, Navia, Andrew W, Wang, Junning, Yang, Annan, Bosse, Timothy L, Kalekar, Radha L, Lowder, Kristen E, Lau, Mai Chan, Elganainy, Dalia, Morales-Oyarvide, Vicente, Rubinson, Douglas A, Singh, Harshabad, Perez, Kimberly, Cleary, James M, Clancy, Thomas E, Wang, Jiping, Mancias, Joseph D, Brais, Lauren K, Hill, Emma R, Kozak, Margaret M, Linehan, David C, Dunne, Richard F, Chang, Daniel T, Koong, Albert C, Hezel, Aram F, Hahn, William C, Shalek, Alex K, Aguirre, Andrew J, Nowak, Jonathan A, Wolpin, Brian M
Published in Cancer research (Chicago, Ill.) (03.02.2023)
Published in Cancer research (Chicago, Ill.) (03.02.2023)
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SDHx mutations and temozolomide in malignant pheochromocytoma and paraganglioma
Perez, Kimberly, Jacene, Heather, Hornick, Jason L, Ma, Chao, Vaz, Nuno, Brais, Lauren K, Alexander, Holly, Baddoo, William, Astone, Kristina, Esplin, Edward D, Garcia, John, Halperin, Daniel M, Kulke, Matthew H, Chan, Jennifer A
Published in Endocrine-related cancer (01.09.2022)
Published in Endocrine-related cancer (01.09.2022)
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FGFR2 Extracellular Domain In-Frame Deletions Are Therapeutically Targetable Genomic Alterations That Function as Oncogenic Drivers in Cholangiocarcinoma
Cleary, James M, Raghavan, Srivatsan, Wu, Qibiao, Li, Yvonne Y, Spurr, Liam F, Gupta, Hersh V, Rubinson, Douglas A, Fetter, Isobel J, Hornick, Jason L, Nowak, Jonathan A, Siravegna, Giulia, Goyal, Lipika, Shi, Lei, Brais, Lauren K, Loftus, Maureen, Shinagare, Atul B, Abrams, Thomas A, Clancy, Thomas E, Wang, Jiping, Patel, Anuj K, Brichory, Franck, Vaslin Chessex, Anne, Sullivan, Ryan J, Keller, Rachel B, Denning, Sarah, Hill, Emma R, Shapiro, Geoffrey I, Pokorska-Bocci, Anna, Zanna, Claudio, Ng, Kimmie, Schrag, Deborah, Jänne, Pasi A, Hahn, William C, Cherniack, Andrew D, Corcoran, Ryan B, Meyerson, Matthew, Daina, Antoine, Zoete, Vincent, Bardeesy, Nabeel, Wolpin, Brian M
Published in Cancer discovery (01.10.2021)
Published in Cancer discovery (01.10.2021)
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