Targeted Doxorubicin-Loaded Bacterially Derived Nano-Cells for the Treatment of Neuroblastoma
Sagnella, Sharon M, Trieu, Jennifer, Brahmbhatt, Himanshu, MacDiarmid, Jennifer A, MacMillan, Alex, Whan, Renee M, Fife, Christopher M, McCarroll, Joshua A, Gifford, Andrew J, Ziegler, David S, Kavallaris, Maria
Published in Molecular cancer therapeutics (01.05.2018)
Published in Molecular cancer therapeutics (01.05.2018)
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Journal Article
A First-Time-In-Human Phase I Clinical Trial of Bispecific Antibody-Targeted, Paclitaxel-Packaged Bacterial Minicells
Solomon, Benjamin J, Desai, Jayesh, Rosenthal, Mark, McArthur, Grant A, Pattison, Scott T, Pattison, Stacey L, MacDiarmid, Jennifer, Brahmbhatt, Himanshu, Scott, Andrew M
Published in PloS one (11.12.2015)
Published in PloS one (11.12.2015)
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Journal Article
Nanocell-mediated delivery of miR-34a counteracts temozolomide resistance in glioblastoma
Khan, Muhammad Babar, Ruggieri, Rosamaria, Jamil, Eesha, Tran, Nhan L, Gonzalez, Camila, Mugridge, Nancy, Gao, Steven, MacDiarmid, Jennifer, Brahmbhatt, Himanshu, Sarkaria, Jann N, Boockvar, John, Symons, Marc
Published in Molecular medicine (Cambridge, Mass.) (25.03.2021)
Published in Molecular medicine (Cambridge, Mass.) (25.03.2021)
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Journal Article
Targeted Doxorubicin Delivery to Brain Tumors via Minicells: Proof of Principle Using Dogs with Spontaneously Occurring Tumors as a Model
MacDiarmid, Jennifer A, Langova, Veronika, Bailey, Dale, Pattison, Scott T, Pattison, Stacey L, Christensen, Neil, Armstrong, Luke R, Brahmbhatt, Vatsala N, Smolarczyk, Katarzyna, Harrison, Matthew T, Costa, Marylia, Mugridge, Nancy B, Sedliarou, Ilya, Grimes, Nicholas A, Kiss, Debra L, Stillman, Bruce, Hann, Christine L, Gallia, Gary L, Graham, Robert M, Brahmbhatt, Himanshu
Published in PloS one (06.04.2016)
Published in PloS one (06.04.2016)
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Journal Article
Nanocell COVID-19 vaccine triggers a novel immune response pathway producing high-affinity antibodies which neutralize all variants of concern
Gao, Steven Y, Amaro-Mugridge, Nancy B, Madrid-Weiss, Jocelyn, Petkovic, Nikolina, Vanegas, Natasha, Visvanathan, Kumar, Williams, Bryan R G, MacDiarmid, Jennifer A, Brahmbhatt, Himanshu
Published in Frontiers in immunology (27.01.2023)
Published in Frontiers in immunology (27.01.2023)
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Journal Article
Bacterially Derived 400 nm Particles for Encapsulation and Cancer Cell Targeting of Chemotherapeutics
MacDiarmid, Jennifer A., Mugridge, Nancy B., Weiss, Jocelyn C., Phillips, Leo, Burn, Adam L., Paulin, Richard P., Haasdyk, Joel E., Dickson, Kristie-Ann, Brahmbhatt, Vatsala N., Pattison, Scott T., James, Alexander C., Al Bakri, Ghalib, Straw, Rodney C., Stillman, Bruce, Graham, Robert M., Brahmbhatt, Himanshu
Published in Cancer cell (01.05.2007)
Published in Cancer cell (01.05.2007)
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Journal Article
Targeting mesothelin receptors with drug-loaded bacterial nanocells suppresses human mesothelioma tumour growth in mouse xenograft models
Alfaleh, Mohamed A, Howard, Christopher B, Sedliarou, Ilya, Jones, Martina L, Gudhka, Reema, Vanegas, Natasha, Weiss, Jocelyn, Suurbach, Julia H, de Bakker, Christopher J, Milne, Michael R, Rumballe, Bree A, MacDiarmid, Jennifer A, Brahmbhatt, Himanshu, Mahler, Stephen M
Published in PloS one (23.10.2017)
Published in PloS one (23.10.2017)
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Journal Article
Translational applications of microRNAs in cancer, and therapeutic implications
Kwok, Grace T., Zhao, Jing Ting, Weiss, Jocelyn, Mugridge, Nancy, Brahmbhatt, Himanshu, MacDiarmid, Jennifer A., Robinson, Bruce G., Sidhu, Stan B.
Published in Non-coding RNA research (01.09.2017)
Published in Non-coding RNA research (01.09.2017)
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Journal Article
Bacterially-Derived Nanocells for Tumor-Targeted Delivery of Chemotherapeutics and Cell Cycle Inhibitors
MacDiarmid, Jennifer A., Madrid-Weiss, Jocelyn, Amaro-Mugridge, Nancy B., Phillips, Leo, Brahmbhatt, Himanshu
Published in Cell cycle (Georgetown, Tex.) (01.09.2007)
Published in Cell cycle (Georgetown, Tex.) (01.09.2007)
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Journal Article
Safety and activity of microRNA-loaded minicells in patients with recurrent malignant pleural mesothelioma: a first-in-man, phase 1, open-label, dose-escalation study
van Zandwijk, Nico, Pavlakis, Nick, Kao, Steven C, Linton, Anthony, Boyer, Michael J, Clarke, Stephen, Huynh, Yennie, Chrzanowska, Agata, Fulham, Michael J, Bailey, Dale L, Cooper, Wendy A, Kritharides, Leonard, Ridley, Lloyd, Pattison, Scott T, MacDiarmid, Jennifer, Brahmbhatt, Himanshu, Reid, Glen
Published in The lancet oncology (01.10.2017)
Published in The lancet oncology (01.10.2017)
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Journal Article
Recurrent pancreatic cancer treated with N-803 and PD-L1 t-haNK followed by an EGFR-targeted nanocell drug conjugate
Moini, Katayoun, Seery, Tara, Nangia, Chaitali, MacDiarmid, Jennifer, Brahmbhatt, Himanshu, Spilman, Patricia, Sender, Lennie, Soon-Shiong, Patrick
Published in The oncologist (Dayton, Ohio) (04.10.2024)
Published in The oncologist (Dayton, Ohio) (04.10.2024)
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Journal Article
Clinical development of TargomiRs, a miRNA mimic-based treatment for patients with recurrent thoracic cancer
Reid, Glen, Kao, Steven C, Pavlakis, Nick, Brahmbhatt, Himanshu, MacDiarmid, Jennifer, Clarke, Stephen, Boyer, Michael, van Zandwijk, Nico
Published in Epigenomics (01.08.2016)
Published in Epigenomics (01.08.2016)
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Journal Article
Minicells: Versatile vectors for targeted drug or si/shRNA cancer therapy
MacDiarmid, Jennifer A, Brahmbhatt, Himanshu
Published in Current opinion in biotechnology (01.12.2011)
Published in Current opinion in biotechnology (01.12.2011)
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Journal Article
Interim data: Phase I/IIa study of EGFR-targeted EDV nanocells carrying cytotoxic drug PNU-159682 (E-EDV-D682) with immunomodulatory adjuvant EDVs carrying α-galactosyl ceramide (EDV-GC) in patients with recurrent, metastatic pancreatic cancer
Lundy, Joanne, Marx, Gavin M., MacDiarmid, Jennifer, Brahmbhatt, Himanshu, Ganju, Vinod
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
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Journal Article
Phase I/IIa Trial in Advanced Pancreatic Ductal Adenocarcinoma Treated with Cytotoxic Drug-Packaged, EGFR-Targeted Nanocells and Glycolipid-Packaged Nanocells
Ganju, Vinod, Marx, Gavin, Pattison, Scott, Amaro-Mugridge, Nancy B, Zhao, Jing-Ting, Williams, Bryan R G, MacDiarmid, Jennifer A, Brahmbhatt, Himanshu
Published in Clinical cancer research (17.01.2024)
Published in Clinical cancer research (17.01.2024)
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Journal Article
Cyto-Immuno-Therapy for Cancer: A Pathway Elicited by Tumor-Targeted, Cytotoxic Drug-Packaged Bacterially Derived Nanocells
Sagnella, Sharon M., Yang, Lu, Stubbs, Gemma E., Boslem, Ebru, Martino-Echarri, Estefania, Smolarczyk, Katarzyna, Pattison, Stacey L., Vanegas, Natasha, St. Clair, Eva, Clarke, Stephen, Boockvar, John, MacDiarmid, Jennifer A., Brahmbhatt, Himanshu
Published in Cancer cell (16.03.2020)
Published in Cancer cell (16.03.2020)
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Journal Article
A Significant Metabolic and Radiological Response after a Novel Targeted MicroRNA-based Treatment Approach in Malignant Pleural Mesothelioma
Kao, Steven C, Fulham, Michael, Wong, Kirby, Cooper, Wendy, Brahmbhatt, Himanshu, MacDiarmid, Jennifer, Pattison, Scott, Sagong, Jin Og, Huynh, Yennie, Leslie, Felicity, Pavlakis, Nick, Clarke, Stephen, Boyer, Michael, Reid, Glen, van Zandwijk, Nico
Published in American journal of respiratory and critical care medicine (15.06.2015)
Published in American journal of respiratory and critical care medicine (15.06.2015)
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Journal Article
A Phase 1 Study of Intravenous EGFR-ErbituxEDVsMIT in Children with Solid or CNS Tumours Expressing Epidermal Growth Factor Receptor
Evans, Louise, Walker, Rick, MacDiarmid, Jennifer, Brahmbhatt, Himanshu, Anazodo, Antoinette, McCowage, Geoffrey, Gifford, Andrew J., Kavallaris, Maria, Trahair, Toby, Ziegler, David S.
Published in Targeted oncology (01.05.2024)
Published in Targeted oncology (01.05.2024)
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Journal Article