Molecular basis for the loss-of-function effects of the Alzheimer's disease–associated R47H variant of the immune receptor TREM2
Sudom, Athena, Talreja, Santosh, Danao, Jean, Bragg, Eric, Kegel, Rob, Min, Xiaoshan, Richardson, Jason, Zhang, Zhongqi, Sharkov, Nikolai, Marcora, Edoardo, Thibault, Steve, Bradley, Jodi, Wood, Steve, Lim, Ai-Ching, Chen, Hang, Wang, Songli, Foltz, Ian N., Sambashivan, Shilpa, Wang, Zhulun
Published in The Journal of biological chemistry (10.08.2018)
Published in The Journal of biological chemistry (10.08.2018)
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Journal Article
867 TriTAC-XR is an extended-release T cell engager platform designed to minimize cytokine release syndrome by reducing Cmax in systemic circulation
Kwant, Kathryn, Rocha, Sony, Stephenson, Katrina, Dayao, Maria, Thothathri, Subramanian, Banzon, Rose, Aaron, Wade, Hemmati, Golzar, Callihan, Evan, Yu, Timothy, O’Rear, Jessica, Bragg, Eric, Kwong, Willis, Situ, Hubert, Hundal, Avneel, Yu, Stephen, Jackson, Taggra, Wright, Kevin, Xiao, Yinghua, To, Linh, Austin, Richard, Lemon, Bryan, Wesche, Holger, Jack Lin, S
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Abstract 933: ProTriTAC is a modular and robust T cell engager prodrug platform with therapeutic index expansion observed across multiple tumor targets
Lin, S. Jack, Rocha, Sony S., Kwant, Kathryn, Dayao, Maria Rosalyn, Ng, Tessie M., Banzon, Raphaela Rose, Thothathri, Subramanian, Aaron, Wade, Callihan, Evan, Hemmati, Golzar, Wright, Kevin J., Barath, Manasi, Xiao, Yinghua, To, Linh, Yu, Timothy, O'Rear, Jessica, Bragg, Eric, Gatto, Scott, Yu, Stephen, Patnaik, Purbasa, Hundal, Avneel, Austin, Richard J., Lemon, Bryan, Wesche, Holger
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Abstract 2927: ITGB6 ProTriTAC™, a protease-activated T cell engager prodrug targeting Integrin-β6 for the treatment of solid tumors
Lin, Regina J., Rocha, Sony S., Dayao, Maria R., Thothathri, Subramanian, Banzon, Raphaela Rose, Wright, Kevin J., Aaron, Wade, Xiao, Yinghua, Bergo, Nick, To, Linh, Bush, Mabel, Barath, Manasi, Yang, Yi, Yu, Timothy, Kwong, Willis, Situ, Hubert, Bragg, Eric, O'Rear, Jessica, Carlin, Kevin, Yu, Stephen, Solorio, Maritza, Lemon, Bryan, Austin, Richard, Wesche, Holger, Lin, S. Jack
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Abstract 2928: TROP2 ProTriTAC™, a protease-activated T cell engager prodrug targeting TROP2 for the treatment of solid tumors
Rocha, Sony S., Lin, Regina, Dayao, Maria R., Banzon, Raphaela Rose, Thothathri, Subramanian, Wright, Kevin J., Aaron, Wade, Xiao, Yinghua, Bergo, Nick, To, Linh, Bush, Mabel, Barath, Manasi, Yu, Timothy, Kwong, Willis, Situ, Hubert, Bragg, Eric, O'Rear, Jessica, Carlin, Kevin, Yu, Stephen, Solorio, Maritza, Lemon, Bryan, Austin, Richard, Wesche, Holger, Lin, S. Jack
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Abstract 2861: TriTAC-XR: An extended-release T cell engager platform designed to minimize cytokine release syndrome
Kwant, Kathryn Strobel, Rocha, Sony S., Yu, Timothy, Stephenson, Katrina, Banzon, Raphaela Rose, Vollhardt, Sydney, Hemmati, Golzar, Callihan, Evan, Aaron, Wade H., Thothathri, Subramanian, O'Rear, Jessica, Bragg, Eric, Kwong, Willis, Situ, Hubert, Hundal, Avneel, Yu, Stephen, Jackson, Taggra, Carlin, Kevin, Xiao, Yinghua, Dayao, Maria Rosalyn, To, Linh, Bergo, Nick, Wright, Kevin, Austin, Richard, Wesche, Holger, Lemon, Bryan, Lin, S. Jack
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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