Constructing ion channels from water-soluble α-helical barrels
Scott, Alistair J., Niitsu, Ai, Kratochvil, Huong T., Lang, Eric J. M., Sengel, Jason T., Dawson, William M., Mahendran, Kozhinjampara R., Mravic, Marco, Thomson, Andrew R., Brady, R. Leo, Liu, Lijun, Mulholland, Adrian J., Bayley, Hagan, DeGrado, William F., Wallace, Mark I., Woolfson, Derek N.
Published in Nature chemistry (01.07.2021)
Published in Nature chemistry (01.07.2021)
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Structural resolution of switchable states of a de novo peptide assembly
Dawson, William M., Lang, Eric J. M., Rhys, Guto G., Shelley, Kathryn L., Williams, Christopher, Brady, R. Leo, Crump, Matthew P., Mulholland, Adrian J., Woolfson, Derek N.
Published in Nature communications (09.03.2021)
Published in Nature communications (09.03.2021)
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Maintaining and breaking symmetry in homomeric coiled-coil assemblies
Rhys, Guto G., Wood, Christopher W., Lang, Eric J. M., Mulholland, Adrian J., Brady, R. Leo, Thomson, Andrew R., Woolfson, Derek N.
Published in Nature communications (08.10.2018)
Published in Nature communications (08.10.2018)
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CCBuilder: an interactive web-based tool for building, designing and assessing coiled-coil protein assemblies
Wood, Christopher W, Bruning, Marc, Ibarra, Amaurys Á, Bartlett, Gail J, Thomson, Andrew R, Sessions, Richard B, Brady, R Leo, Woolfson, Derek N
Published in Bioinformatics (Oxford, England) (01.11.2014)
Published in Bioinformatics (Oxford, England) (01.11.2014)
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Differential sensing with arrays of de novo designed peptide assemblies
Dawson, William M., Shelley, Kathryn L., Fletcher, Jordan M., Scott, D. Arne, Lombardi, Lucia, Rhys, Guto G., LaGambina, Tania J., Obst, Ulrike, Burton, Antony J., Cross, Jessica A., Davies, George, Martin, Freddie J. O., Wiseman, Francis J., Brady, R. Leo, Tew, David, Wood, Christopher W., Woolfson, Derek N.
Published in Nature communications (24.01.2023)
Published in Nature communications (24.01.2023)
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Cryo-transmission electron microscopy structure of a gigadalton peptide fiber of de novo design
Sharp, Thomas H, Bruning, Marc, Mantell, Judith, Sessions, Richard B, Thomson, Andrew R, Zaccai, Nathan R, Brady, R. Leo, Verkade, Paul, Woolfson, Derek N
Published in Proceedings of the National Academy of Sciences - PNAS (14.08.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (14.08.2012)
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A Basis Set of de Novo Coiled-Coil Peptide Oligomers for Rational Protein Design and Synthetic Biology
Fletcher, Jordan M, Boyle, Aimee L, Bruning, Marc, Bartlett, Gail J, Vincent, Thomas L, Zaccai, Nathan R, Armstrong, Craig T, Bromley, Elizabeth H. C, Booth, Paula J, Brady, R. Leo, Thomson, Andrew R, Woolfson, Derek N
Published in ACS synthetic biology (15.06.2012)
Published in ACS synthetic biology (15.06.2012)
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Mutations in EKLF/KLF1 form the molecular basis of the rare blood group In(Lu) phenotype
Singleton, Belinda K., Burton, Nicholas M., Green, Carole, Brady, R.Leo, Anstee, David J.
Published in Blood (01.09.2008)
Published in Blood (01.09.2008)
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The monovalent cation leak in overhydrated stomatocytic red blood cells results from amino acid substitutions in the Rh-associated glycoprotein
Bruce, Lesley J., Guizouarn, Hélène, Burton, Nicholas M., Gabillat, Nicole, Poole, Joyce, Flatt, Joanna F., Brady, R. Leo, Borgese, Franck, Delaunay, Jean, Stewart, Gordon W.
Published in Blood (05.02.2009)
Published in Blood (05.02.2009)
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Mutations in the second zinc finger of human EKLF reduce promoter affinity but give rise to benign and disease phenotypes
Singleton, Belinda K., Lau, Winnie, Fairweather, Victoria S.S., Burton, Nicholas M., Wilson, Marieangela C., Parsons, Steve F., Richardson, Ben M., Trakarnsanga, Kongtana, Brady, R. Leo, Anstee, David J., Frayne, Jan
Published in Blood (15.09.2011)
Published in Blood (15.09.2011)
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CD151, the first member of the tetraspanin (TM4) superfamily detected on erythrocytes, is essential for the correct assembly of human basement membranes in kidney and skin
Karamatic Crew, Vanja, Burton, Nicholas, Kagan, Alexander, Green, Carole A., Levene, Cyril, Flinter, Frances, Brady, R. Leo, Daniels, Geoff, Anstee, David J.
Published in Blood (15.10.2004)
Published in Blood (15.10.2004)
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Structural effects of the highly protective V127 polymorphism on human prion protein
Hosszu, Laszlo L. P., Conners, Rebecca, Sangar, Daljit, Batchelor, Mark, Sawyer, Elizabeth B., Fisher, Stuart, Cliff, Matthew J., Hounslow, Andrea M., McAuley, Katherine, Leo Brady, R., Jackson, Graham S., Bieschke, Jan, Waltho, Jonathan P., Collinge, John
Published in Communications biology (29.07.2020)
Published in Communications biology (29.07.2020)
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Correlation of in situ mechanosensitive responses of the Moraxella catarrhalis adhesin UspA1 with fibronectin and receptor CEACAM1 binding
Agnew, Christopher, Borodina, Elena, Zaccai, Nathan R, Conners, Rebecca, Burton, Nicholas M, Vicary, James A, Cole, David K, Antognozzi, Massimo, Virji, Mumtaz, Brady, R. Leo
Published in Proceedings of the National Academy of Sciences - PNAS (13.09.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (13.09.2011)
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The Moraxella adhesin UspA1 binds to its human CEACAM1 receptor by a deformable trimeric coiled-coil
Conners, Rebecca, Hill, Darryl J, Borodina, Elena, Agnew, Christopher, Daniell, Sarah J, Burton, Nicholas M, Sessions, Richard B, Clarke, Anthony R, Catto, Lucy E, Lammie, Donna, Wess, Timothy, Brady, R Leo, Virji, Mumtaz
Published in The EMBO journal (18.06.2008)
Published in The EMBO journal (18.06.2008)
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Structure and kinetic characterization of human sperm-specific glyceraldehyde-3-phosphate dehydrogenase, GAPDS
Chaikuad, Apirat, Shafqat, Naeem, Al-Mokhtar, Ruby, Cameron, Gus, Clarke, Anthony R, Brady, R Leo, Oppermann, Udo, Frayne, Jan, Yue, Wyatt W
Published in Biochemical journal (15.04.2011)
Published in Biochemical journal (15.04.2011)
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Installing hydrolytic activity into a completely de novo protein framework
Burton, Antony J., Thomson, Andrew R., Dawson, William M., Brady, R. Leo, Woolfson, Derek N.
Published in Nature chemistry (01.09.2016)
Published in Nature chemistry (01.09.2016)
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Late diagnosis of primary hyperoxaluria type 2 in the adult: effect of a novel mutation in GRHPR gene on enzymatic activity and molecular modeling
Levin-Iaina, Nomy, Dinour, Dganit, Romero, Lina, Ron, Rotem, Brady, R Leo, Cramer, Scott D, Holtzman, Eli J
Published in The Journal of urology (01.05.2009)
Published in The Journal of urology (01.05.2009)
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An Unusual Helix-Turn-Helix Protease Inhibitory Motif in a Novel Trypsin Inhibitor from Seeds of Veronica (Veronica hederifolia L.)
Conners, Rebecca, Konarev, Alexander V., Forsyth, Jane, Lovegrove, Alison, Marsh, Justin, Joseph-Horne, Timothy, Shewry, Peter, Brady, R. Leo
Published in The Journal of biological chemistry (21.09.2007)
Published in The Journal of biological chemistry (21.09.2007)
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Structural Basis of Substrate Specificity in Human Glyoxylate Reductase/Hydroxypyruvate Reductase
Booth, Michael P.S., Conners, R., Rumsby, Gill, Brady, R. Leo
Published in Journal of molecular biology (30.06.2006)
Published in Journal of molecular biology (30.06.2006)
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