An Adaptive Physiologically Based Pharmacokinetic–Driven Design to Investigate the Effect of Itraconazole and Rifampicin on the Pharmacokinetics of Molibresib (GSK525762) in Healthy Female Volunteers
Riddell, Kylie, Patel, Aarti, Collins, Gary, Zhou, Yanyan, Schramek, Dan, Kremer, Brandon E., Ferron‐Brady, Geraldine
Published in Journal of clinical pharmacology (01.01.2021)
Published in Journal of clinical pharmacology (01.01.2021)
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Journal Article
Exposure–Response Analyses for Therapeutic Dose Selection of Belantamab Mafodotin in Patients With Relapsed/Refractory Multiple Myeloma
Ferron‐Brady, Geraldine, Rathi, Chetan, Collins, Jon, Struemper, Herbert, Opalinska, Joanna, Visser, Sandra, Jewell, Roxanne C.
Published in Clinical pharmacology and therapeutics (01.11.2021)
Published in Clinical pharmacology and therapeutics (01.11.2021)
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Journal Article
Safety, pharmacokinetic, pharmacodynamic and clinical activity of molibresib for the treatment of nuclear protein of the testis carcinoma and other cancers: Results of a Phase I/II open‐label, dose escalation study
Cousin, Sophie, Blay, Jean‐Yves, Garcia, Irene Braña, Bono, Johann S., Le Tourneau, Christophe, Moreno, Victor, Trigo, Jose, Hann, Christine L., Azad, Arun A., Im, Seock‐Ah, Cassier, Philippe A., French, Christopher A., Italiano, Antoine, Keedy, Vicki L., Plummer, Ruth, Sablin, Marie‐Paule, Hemming, Matthew L., Ferron‐Brady, Geraldine, Wyce, Anastasia, Khaled, Ahmed, Datta, Antara, Foley, Shawn W., McCabe, Michael T., Wu, Yuehui, Horner, Thierry, Kremer, Brandon E., Dhar, Arindam, O'Dwyer, Peter J., Shapiro, Geoffrey I., Piha‐Paul, Sarina A.
Published in International journal of cancer (15.03.2022)
Published in International journal of cancer (15.03.2022)
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Population pharmacokinetics of belantamab mafodotin, a BCMA‐targeting agent in patients with relapsed/refractory multiple myeloma
Rathi, Chetan, Collins, Jon, Struemper, Herbert, Opalinska, Joanna, Jewell, Roxanne C., Ferron‐Brady, Geraldine
Published in CPT: pharmacometrics and systems pharmacology (01.08.2021)
Published in CPT: pharmacometrics and systems pharmacology (01.08.2021)
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Journal Article
Momelotinib: Mechanism of action, clinical, and translational science
Vlasakakis, Georgios, McCabe, Michael T., Ho, Yu Liu, Ferron‐Brady, Geraldine, Martin, Paul, Bentley, Darren, Ellis, Catherine, Antonysamy, Mary, Visser, Sandra A. G.
Published in Clinical and translational science (01.08.2024)
Published in Clinical and translational science (01.08.2024)
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A randomized, active- and placebo-controlled study of the efficacy and safety of different doses of dutasteride versus placebo and finasteride in the treatment of male subjects with androgenetic alopecia
Gubelin Harcha, Walter, MD, Barboza Martínez, Julia, MD, Tsai, Tsen-Fang, MD, Katsuoka, Kensei, MD, Kawashima, Makoto, MD, PhD, Tsuboi, Ryoji, MD, PhD, Barnes, Allison, MS, Ferron-Brady, Geraldine, PharmD, PhD, Chetty, Dushen, PhD
Published in Journal of the American Academy of Dermatology (01.03.2014)
Published in Journal of the American Academy of Dermatology (01.03.2014)
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Journal Article
Population pharmacokinetic modeling of molibresib and its active metabolites in patients with solid tumors: A semimechanistic autoinduction model
Krishnatry, Anu Shilpa, Voelkner, Alexander, Dhar, Arindam, Prohn, Marita, Ferron‐Brady, Geraldine
Published in CPT: pharmacometrics and systems pharmacology (01.07.2021)
Published in CPT: pharmacometrics and systems pharmacology (01.07.2021)
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Journal Article
Building an adaptive dose simulation framework to aid dose and schedule selection
Hooijmaijers, Richard, Parasrampuria, Ridhi, Marostica, Eleonora, Ferron‐Brady, Geraldine, Post, Teun M., Visser, Sandra A. G.
Published in CPT: pharmacometrics and systems pharmacology (01.11.2023)
Published in CPT: pharmacometrics and systems pharmacology (01.11.2023)
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Journal Article
Exposure–response analysis of adverse events associated with molibresib and its active metabolites in patients with solid tumors
Krishnatry, Anu Shilpa, Hanze, Eva, Bergsma, Tim, Dhar, Arindam, Prohn, Marita, Ferron‐Brady, Geraldine
Published in CPT: pharmacometrics and systems pharmacology (01.05.2022)
Published in CPT: pharmacometrics and systems pharmacology (01.05.2022)
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Journal Article
Longitudinal efficacy and safety modeling and simulation framework to aid dose selection of belantamab mafodotin for patients with multiple myeloma
Collins, Jon, van Noort, Martijn, Rathi, Chetan, Post, Teun M, Struemper, Herbert, Jewell, Roxanne C, Ferron-Brady, Geraldine
Published in CPT: pharmacometrics and systems pharmacology (01.10.2023)
Published in CPT: pharmacometrics and systems pharmacology (01.10.2023)
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Journal Article
Phase I evaluation of the safety, tolerability, and pharmacokinetics of GSK3640254, a next‐generation HIV‐1 maturation inhibitor
Joshi, Samit R., Fernando, Disala, Igwe, Stephanie, McKenzie, Litza, Krishnatry, Anu S., Halliday, Fiona, Zhan, Joyce, Greene, Thomas J., Xu, Jianfeng, Ferron‐Brady, Geraldine, Lataillade, Max, Min, Sherene
Published in Pharmacology research & perspectives (01.12.2020)
Published in Pharmacology research & perspectives (01.12.2020)
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Lysine specific demethylase 1 inactivation enhances differentiation and promotes cytotoxic response when combined with all- trans retinoic acid in acute myeloid leukemia across subtypes
Smitheman, Kimberly N, Severson, Tesa M, Rajapurkar, Satyajit R, McCabe, Michael T, Karpinich, Natalie, Foley, James, Pappalardi, Melissa B, Hughes, Ashley, Halsey, Wendy, Thomas, Elizabeth, Traini, Christopher, Federowicz, Kelly E, Laraio, Jenny, Mobegi, Fredrick, Ferron-Brady, Geraldine, Prinjha, Rabinder K, Carpenter, Christopher L, Kruger, Ryan G, Wessels, Lodewyk, Mohammad, Helai P
Published in Haematologica (Roma) (01.06.2019)
Published in Haematologica (Roma) (01.06.2019)
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