Dnmt1 has de novo activity targeted to transposable elements
Haggerty, Chuck, Kretzmer, Helene, Riemenschneider, Christina, Kumar, Abhishek Sampath, Mattei, Alexandra L., Bailly, Nina, Gottfreund, Judith, Giesselmann, Pay, Weigert, Raha, Brändl, Björn, Giehr, Pascal, Buschow, René, Galonska, Christina, von Meyenn, Ferdinand, Pappalardi, Melissa B., McCabe, Michael T., Wittler, Lars, Giesecke-Thiel, Claudia, Mielke, Thorsten, Meierhofer, David, Timmermann, Bernd, Müller, Franz-Josef, Walter, Jörn, Meissner, Alexander
Published in Nature structural & molecular biology (01.07.2021)
Published in Nature structural & molecular biology (01.07.2021)
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Journal Article
Analysis of short tandem repeat expansions and their methylation state with nanopore sequencing
Giesselmann, Pay, Brändl, Björn, Raimondeau, Etienne, Bowen, Rebecca, Rohrandt, Christian, Tandon, Rashmi, Kretzmer, Helene, Assum, Günter, Galonska, Christina, Siebert, Reiner, Ammerpohl, Ole, Heron, Andrew, Schneider, Susanne A., Ladewig, Julia, Koch, Philipp, Schuldt, Bernhard M., Graham, James E., Meissner, Alexander, Müller, Franz-Josef
Published in Nature biotechnology (01.12.2019)
Published in Nature biotechnology (01.12.2019)
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Journal Article
An Organoid-Based Model of Cortical Development Identifies Non-Cell-Autonomous Defects in Wnt Signaling Contributing to Miller-Dieker Syndrome
Iefremova, Vira, Manikakis, George, Krefft, Olivia, Jabali, Ammar, Weynans, Kevin, Wilkens, Ruven, Marsoner, Fabio, Brändl, Björn, Müller, Franz-Josef, Koch, Philipp, Ladewig, Julia
Published in Cell reports (Cambridge) (04.04.2017)
Published in Cell reports (Cambridge) (04.04.2017)
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Journal Article
Enhanced cortical neural stem cell identity through short SMAD and WNT inhibition in human cerebral organoids facilitates emergence of outer radial glial cells
Rosebrock, Daniel, Arora, Sneha, Mutukula, Naresh, Volkman, Rotem, Gralinska, Elzbieta, Balaskas, Anastasios, Aragonés Hernández, Amèlia, Buschow, René, Brändl, Björn, Müller, Franz-Josef, Arndt, Peter F., Vingron, Martin, Elkabetz, Yechiel
Published in Nature cell biology (01.06.2022)
Published in Nature cell biology (01.06.2022)
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Journal Article
Classification of Brain Tumors by Nanopore Sequencing of Cell-Free DNA from Cerebrospinal Fluid
Afflerbach, Ann-Kristin, Rohrandt, Christian, Brändl, Björn, Sönksen, Marthe, Hench, Jürgen, Frank, Stephan, Börnigen, Daniela, Alawi, Malik, Mynarek, Martin, Winkler, Beate, Ricklefs, Franz, Synowitz, Michael, Dührsen, Lasse, Rutkowski, Stefan, Wefers, Annika K, Müller, Franz-Josef, Schoof, Melanie, Schüller, Ulrich
Published in Clinical chemistry (Baltimore, Md.) (04.01.2024)
Published in Clinical chemistry (Baltimore, Md.) (04.01.2024)
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Journal Article
Comparison of methylation estimates obtained via MinION nanopore sequencing and sanger bisulfite sequencing in the TRPA1 promoter region
Gombert, Sara, Jahn, Kirsten, Pathak, Hansi, Burkert, Alexandra, Schmidt, Gunnar, Wiehlmann, Lutz, Davenport, Colin, Brändl, Björn, Müller, Franz-Josef, Leffler, Andreas, Deest, Maximilian, Frieling, Helge
Published in BMC medical genomics (23.10.2023)
Published in BMC medical genomics (23.10.2023)
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Journal Article
Generation of an induced pluripotent stem cell line, ZIPi021-A, from fibroblasts of a Prader-Willi syndrome patient with maternal uniparental disomy (mUPD)
Heseding, Hannah, Jahn, Kirsten, Brändl, Björn, Haase, Alexandra, Shum, Ian O., Kohrn, Tim, Bleich, Stefan, Frieling, Helge, Martin, Ulrich, Müller, Franz-Josef, Wunderlich, Stephanie, Deest, Maximilian
Published in Stem cell research (01.09.2023)
Published in Stem cell research (01.09.2023)
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Journal Article
An automated and high-throughput-screening compatible pluripotent stem cell-based test platform for developmental and reproductive toxicity assessment of small molecule compounds
Witt, Gesa, Keminer, Oliver, Leu, Jennifer, Tandon, Rashmi, Meiser, Ina, Willing, Anne, Winschel, Ingo, Abt, Jana-Christin, Brändl, Björn, Sébastien, Isabelle, Friese, Manuel A., Müller, Franz-Josef, Neubauer, Julia C., Claussen, Carsten, Zimmermann, Heiko, Gribbon, Philip, Pless, Ole
Published in Cell biology and toxicology (01.04.2021)
Published in Cell biology and toxicology (01.04.2021)
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Journal Article
Generation of an iPSC line of a patient with Angelman syndrome due to an imprinting defect
Neureiter, Anika, Brändl, Björn, Hiber, Michaela, Tandon, Rashmi, Müller, Franz-Josef, Steenpass, Laura
Published in Stem cell research (01.12.2018)
Published in Stem cell research (01.12.2018)
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Journal Article
Generation of two human isogenic iPSC lines from fetal dermal fibroblasts
Tandon, Rashmi, Brändl, Björn, Baryshnikova, Natalya, Landshammer, Alexandro, Steenpaß, Laura, Keminer, Oliver, Pless, Ole, Müller, Franz-Josef
Published in Stem cell research (01.12.2018)
Published in Stem cell research (01.12.2018)
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Journal Article
Utilizing Regulatory Networks for Pluripotency Assessment in Stem Cells
Brändl, Björn, Schuldt, Bernhard M., Böhnke, Lena, Keminer, Oliver, Vaas, Lea A. I., Fischer, Rainer, Müller, Franz-Josef, Pless, Ole
Published in Current stem cell reports (01.09.2016)
Published in Current stem cell reports (01.09.2016)
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Journal Article
TETs compete with DNMT3 activity in pluripotent cells at thousands of methylated somatic enhancers
Charlton, Jocelyn, Jung, Eunmi J., Mattei, Alexandra L., Bailly, Nina, Liao, Jing, Martin, Eric J., Giesselmann, Pay, Brändl, Björn, Stamenova, Elena K., Müller, Franz-Josef, Kiskinis, Evangelos, Gnirke, Andreas, Smith, Zachary D., Meissner, Alexander
Published in Nature genetics (01.08.2020)
Published in Nature genetics (01.08.2020)
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Journal Article
Nanopore SimulatION - a raw data simulator for Nanopore Sequencing
Rohrandt, Christian, Kraft, Nadine, Gieselmann, Pay, Brandl, Bjorn, Schuldt, Bernhard M., Jetzek, Ulrich, Muller, Franz-Josef
Published in 2018 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) (01.12.2018)
Published in 2018 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) (01.12.2018)
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Conference Proceeding
Stem cell reprogramming: Basic implications and future perspective for movement disorders
Brändl, Björn, Schneider, Susanne A., Loring, Jeanne F., Hardy, John, Gribbon, Philip, Müller, Franz-Josef
Published in Movement disorders (01.03.2015)
Published in Movement disorders (01.03.2015)
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Journal Article
Autonomous transposons tune their sequences to ensure somatic suppression
Ilık, İbrahim Avşar, Glažar, Petar, Tse, Kevin, Brändl, Björn, Meierhofer, David, Müller, Franz-Josef, Smith, Zachary D., Aktaş, Tuğçe
Published in Nature (London) (29.02.2024)
Published in Nature (London) (29.02.2024)
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Journal Article
Developmental trajectories and cooperating genomic events define molecular subtypes of BCR::ABL1-positive ALL
Bastian, Lorenz, Beder, Thomas, Barz, Malwine J., Bendig, Sonja, Bartsch, Lorenz, Walter, Wencke, Wolgast, Nadine, Brändl, Björn, Rohrandt, Christian, Hansen, Björn-Thore, Hartmann, Alina M., Iben, Katharina, Das Gupta, Dennis, Denker, Miriam, Zimmermann, Johannes, Wittig, Michael, Chitadze, Guranda, Neumann, Martin, Schneller, Folker, Fiedler, Walter, Steffen, Björn, Stelljes, Matthias, Faul, Christoph, Schwartz, Stefan, Müller, Franz-Josef, Cario, Gunnar, Harder, Lana, Haferlach, Claudia, Pfeifer, Heike, Gökbuget, Nicola, Brüggemann, Monika, Baldus, Claudia D.
Published in Blood (04.04.2024)
Published in Blood (04.04.2024)
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Journal Article
Molecular Subtypes in BCR::ABL1-Positive ALL Are Defined By Cellular Origins and Cooperating Genomic Events
Bastian, Lorenz, Beder, Thomas, Barz, Malwine, Bendig, Sonja, Bartsch, Lorenz, Walter, Wencke, Wolgast, Nadine, Brändl, Björn, Rohrandt, Christian, Hansen, Björn-Thore, Hartmann, Alina M., Iben, Katharina, Bultmann, Miriam, Zimmermann, Johannes, Wittig, Michael, Chitadze, Guranda, Neumann, Martin, Schneller, Folker, Fiedler, Walter, Steffen, Björn, Stelljes, Matthias, Faul, Christoph, Schwartz, Stefan, Müller, Franz-Josef, Cario, Gunnar, Harder, Lana, Haferlach, Claudia, Pfeifer, Heike, Goekbuget, Nicola, Brüggemann, Monika, Baldus, Claudia D
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Mutations in PMPCB Encoding the Catalytic Subunit of the Mitochondrial Presequence Protease Cause Neurodegeneration in Early Childhood
Vögtle, F.-Nora, Brändl, Björn, Larson, Austin, Pendziwiat, Manuela, Friederich, Marisa W., White, Susan M., Basinger, Alice, Kücükköse, Cansu, Muhle, Hiltrud, Jähn, Johanna A., Keminer, Oliver, Helbig, Katherine L., Delto, Carolyn F., Myketin, Lisa, Mossmann, Dirk, Burger, Nils, Miyake, Noriko, Burnett, Audrey, van Baalen, Andreas, Lovell, Mark A., Matsumoto, Naomichi, Walsh, Maie, Yu, Hung-Chun, Shinde, Deepali N., Stephani, Ulrich, Van Hove, Johan L.K., Müller, Franz-Josef, Helbig, Ingo
Published in American journal of human genetics (05.04.2018)
Published in American journal of human genetics (05.04.2018)
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Journal Article
OTHR-03. CLASSIFICATION OF BRAIN TUMORS BY NANOPORE SEQUENCING OF CELL-FREE DNA FROM CEREBROSPINAL FLUID
Afflerbach, Ann-Kristin, Rohrandt, Christian, Brändl, Björn, Sönksen, Marthe, Hench, Jürgen, Frank, Stephan, Börnigen, Daniela, Alawi, Malik, Mynarek, Martin, Winkler, Beate, Ricklefs, Franz, Synowitz, Michael, Dührsen, Lasse, Rutkowski, Stefan, Wefers, Annika K, Müller, Franz-Josef, Schoof, Melanie, Schüller, Ulrich
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
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Journal Article
Rapid intraoperative amplicon sequencing of CNS tumor markers
Evers, Maximilian, Brändl, Björn, Rohrandt, Christian, Kubelt-Kwamin, Carolin, Müller, Franz-Josef, Danso, Dominik, Maicher, André, Wang, Gaojianyong, Friedrichsen, Sönke, Kolkenbrock, Stephan
Published in Computational and structural biotechnology journal (01.12.2024)
Published in Computational and structural biotechnology journal (01.12.2024)
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Journal Article