Leukemic extracellular vesicles induce chimeric antigen receptor T cell dysfunction in chronic lymphocytic leukemia
Cox, Michelle J., Lucien, Fabrice, Sakemura, Reona, Boysen, Justin C., Kim, Yohan, Horvei, Paulina, Manriquez Roman, Claudia, Hansen, Michael J., Tapper, Erin E., Siegler, Elizabeth L., Forsman, Cynthia, Crotts, Sydney B., Schick, Kendall J., Hefazi, Mehrdad, Ruff, Michael W., Can, Ismail, Adada, Mohamad, Bezerra, Evandro, Kankeu Fonkoua, Lionel Aurelien, Nevala, Wendy K., Braggio, Esteban, Ding, Wei, Parikh, Sameer A., Kay, Neil E., Kenderian, Saad S.
Published in Molecular therapy (07.04.2021)
Published in Molecular therapy (07.04.2021)
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Platelet-derived growth factor (PDGF)–PDGF receptor interaction activates bone marrow–derived mesenchymal stromal cells derived from chronic lymphocytic leukemia: implications for an angiogenic switch
Ding, Wei, Knox, Traci R., Tschumper, Renee C., Wu, Wenting, Schwager, Susan M., Boysen, Justin C., Jelinek, Diane F., Kay, Neil E.
Published in Blood (21.10.2010)
Published in Blood (21.10.2010)
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The novel receptor tyrosine kinase Axl is constitutively active in B-cell chronic lymphocytic leukemia and acts as a docking site of nonreceptor kinases: implications for therapy
Ghosh, Asish K., Secreto, Charla, Boysen, Justin, Sassoon, Traci, Shanafelt, Tait D., Mukhopadhyay, Debabrata, Kay, Neil E.
Published in Blood (10.02.2011)
Published in Blood (10.02.2011)
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Journal Article
SIRT3 overexpression and epigenetic silencing of catalase regulate ROS accumulation in CLL cells activating AXL signaling axis
Maiti, Guru P., Sinha, Sutapa, Mahmud, Hasan, Boysen, Justin, Mendez, Mariana T., Vesely, Sara K., Holter-Chakrabarty, Jennifer, Kay, Neil E., Ghosh, Asish K.
Published in Blood cancer journal (New York) (17.05.2021)
Published in Blood cancer journal (New York) (17.05.2021)
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B cell receptor signaling drives APOBEC3 expression via direct enhancer regulation in chronic lymphocytic leukemia B cells
Wang, Zhiquan, Yan, Huihuang, Boysen, Justin C., Secreto, Charla R., Tschumper, Renee C., Ali, Dania, Guo, Qianqian, Zhong, Jian, Zhou, Jiaqi, Gan, Haiyun, Yu, Chuanhe, Jelinek, Diane F., Slager, Susan L., Parikh, Sameer A., Braggio, Esteban, Kay, Neil E.
Published in Blood cancer journal (New York) (01.07.2022)
Published in Blood cancer journal (New York) (01.07.2022)
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Brief Report: Natural History of Individuals With Clinically Recognized Monoclonal B-Cell Lymphocytosis Compared With Patients With Rai 0 Chronic Lymphocytic Leukemia
SHANAFELT, Tait D, KAY, Neil E, SCHWAGER, Susan, BOWEN, Deborah, SLAGER, Susan L, HANSON, Curtis A, RABE, Kari G, CALL, Timothy G, ZENT, Clive S, MADDOCKS, Kami, JENKINS, Greg, JELINEK, Diane F, MORICE, William G, BOYSEN, Justin
Published in Journal of clinical oncology (20.08.2009)
Published in Journal of clinical oncology (20.08.2009)
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Upregulation of AXL and β-catenin in chronic lymphocytic leukemia cells cultured with bone marrow stroma cells is associated with enhanced drug resistance
Sinha, Sutapa, Secreto, Charla R., Boysen, Justin C., Lesnick, Connie, Wang, Zhiquan, Ding, Wei, Call, Timothy G., Kenderian, Saad J., Parikh, Sameer A., Warner, Steven L., Bearss, David J., Ghosh, Asish K., Kay, Neil E.
Published in Blood cancer journal (New York) (18.02.2021)
Published in Blood cancer journal (New York) (18.02.2021)
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Journal Article
AXL Inhibition Improves the Antitumor Activity of Chimeric Antigen Receptor T Cells
Sakemura, R Leo, Hefazi, Mehrdad, Cox, Michelle J, Siegler, Elizabeth L, Sinha, Sutapa, Hansen, Michael J, Stewart, Carli M, Feigin, Jennifer M, Manriquez Roman, Claudia, Schick, Kendall J, Can, Ismail, Tapper, Erin E, Horvei, Paulina, Adada, Mohamad M, Bezerra, Evandro D, Kankeu Fonkoua, Lionel Aurelien, Ruff, Michael W, Forsman, Cynthia L, Nevala, Wendy K, Boysen, Justin C, Tschumper, Renee C, Grand, Cory L, Kuchimanchi, Kameswara R, Mouritsen, Lars, Foulks, Jason M, Warner, Steven L, Call, Timothy G, Parikh, Sameer A, Ding, Wei, Kay, Neil E, Kenderian, Saad S
Published in Cancer immunology research (01.09.2023)
Published in Cancer immunology research (01.09.2023)
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Journal Article
Chronic lymphocytic leukemia cells from ibrutinib treated patients are sensitive to Axl receptor tyrosine kinase inhibitor therapy
Sinha, Sutapa, Boysen, Justin C, Chaffee, Kari G, Kabat, Brian F, Slager, Susan L, Parikh, Sameer A, Secreto, Charla R, Call, Tim, Shanafelt, Tait D, Leis, Jose F, Warner, Steven L, Bearss, David J, Ghosh, Asish K, Kay, Neil E
Published in Oncotarget (14.12.2018)
Published in Oncotarget (14.12.2018)
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Journal Article
Bi‐directional activation between mesenchymal stem cells and CLL B‐cells: implication for CLL disease progression
Ding, Wei, Nowakowski, Grzegorz S., Knox, Traci R., Boysen, Justin C., Maas, Mary L., Schwager, Susan M., Wu, Wenting, Wellik, Linda E., Dietz, Allan B., Ghosh, Asish K., Secreto, Charla R., Medina, Kay L., Shanafelt, Tait D., Zent, Clive S., Call, Timothy G., Kay, Neil E.
Published in British journal of haematology (01.11.2009)
Published in British journal of haematology (01.11.2009)
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Journal Article
Aberrant activation of AXL may drive progression of squamous cell carcinoma in CLL patients: a mechanistic study with clinical implications
Sinha, Sutapa, Guo, Ray, Del Busso, Miles D., Han, Weiguo, Boysen, Justin, Wellik, Linda E., Ghosh, Asish K., Kay, Neil E.
Published in British journal of cancer (24.08.2024)
Published in British journal of cancer (24.08.2024)
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Journal Article
Cellular Interactions within Clonal Dendritic Cell Aggregates Drive Immune Tolerance in Chronic Myelomonocytic Leukemia Bone Marrow Microenvironment
Mangaonkar, Abhishek A, Lasho, Terra L, Boysen, Justin, Finke, Christy M, Fernandez, Jenna A., Villasboas, Jose. C., Dean, Christopher, Ferrer, Alejandro, Binder, Moritz, Wang, Liguo, Lee, Jeong-Heon, Reichard, Kaaren K., Patnaik, Mrinal M.
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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B Cell Receptor Signaling Drives APOBEC3 Expression Via Direct Enhancer Regulation in Chronic Lymphocytic Leukemia B Cells
Wang, Zhiquan, Yan, Huihuang, Boysen, Justin C., Secreto, Charla R., Braggio, Esteban, Slager, Susan L., Parikh, Sameer A., Kay, Neil E.
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Targeted Axl Inhibition Primes Chronic Lymphocytic Leukemia B Cells to Apoptosis and Shows Synergistic/Additive Effects in Combination with BTK Inhibitors
Sinha, Sutapa, Boysen, Justin, Nelson, Michael, Secreto, Charla, Warner, Steven L, Bearss, David J, Lesnick, Connie, Shanafelt, Tait D, Kay, Neil E, Ghosh, Asish K
Published in Clinical cancer research (01.05.2015)
Published in Clinical cancer research (01.05.2015)
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Β-Catenin and Axl Receptor Tyrosine Kinase Modulation in CLL B-Cells with Co-Culture on Marrow Stromal Cells: Implications for Drug Resistance
Sinha, Sutapa, Secreto, Charla R, Boysen, Justin C., Warner, Steven L., Bearss, David J., Ghosh, Asish K, Kay, Neil E.
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Analytical Considerations in Nanoscale Flow Cytometry of Extracellular Vesicles to Achieve Data Linearity
Gomes, Janice, Lucien, Fabrice, Cooper, Tyler T., Kim, Yohan, Williams, Karla C., Liao, XinYang, Kaufman, Lauren, Lagugné-Labarthet, Francois, Kenyon, Oliver, Boysen, Justin, Kay, Neil E., McIntyre, Christopher W., Leong, Hon S.
Published in Thrombosis and haemostasis (01.09.2018)
Published in Thrombosis and haemostasis (01.09.2018)
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Journal Article
Targeting Aberrant Chromatin in Chronic Lymphocytic Leukemia
Wang, Zhiquan, Boysen, Justin C., Yan, Huihuang, Secreto, Charla R., Parikh, Sameer A., Kenderian, Saad S., Ding, Wei, Braggio, Esteban, Slager, Susan L., Kay, Neil E.
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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PD-1 Expression in Lymphoma Cells Mediates Cellular Proliferation By Engaging Phosphatase SHP-1/SHP-2
Sinha, Sutapa, Price-Troska, Tammy, Tian, Shulan, Sakemura, R. Leo, Yan, Huihuang, Boysen, Justin, Wang, Zhiquan, Wu, Xiaosheng, He, Rong, Shi, Min, Wang, Yucai, Klee, Eric W, Parikh, Sameer A., Hampel, Paul J, Call, Timothy G., Leis, Jose F., Shanafelt, Tait D., Ansell, Stephen M, Kenderian, Saad S., Kay, Neil E., Ding, Wei
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Enhanced Expression of Beta-Catenin and Axl Receptor Tyrosine Kinase (RTK) in Chronic Lymphocytic Leukemia (CLL) B-Cells with Co-Culture on Marrow Stromal Cells: Implications for Leukemic Cell Drug Resistance
Sinha, Sutapa, Secreto, Charla R, Boysen, Justin C., Warner, Steven L., Bearss, David J., Ghosh, Asish K, Kay, Neil E.
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Journal Article
Differential Susceptibility to Senescence in CART Cells Based on Co-Stimulatory Signaling
Can, Ismail, Sakemura, Reona Leo, Manriquez-Roman, Claudia, Sirpilla, Olivia, Stewart, Carli M., Yun, Kun, Cox, Michelle J., Huynh, Truc, Girsch, James H., Ogbodo, Ekene J., Kankeu Fonkoua, Lionel A., Hefazi, Mehrdad, Ruff, Michael W., Boysen, Justin C., Siegler, Elizabeth L., Ekiz, Atakan, Kenderian, Saad S., Kay, Neil E.
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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