LY6E mediates an evolutionarily conserved enhancement of virus infection by targeting a late entry step
Mar, Katrina B., Rinkenberger, Nicholas R., Boys, Ian N., Eitson, Jennifer L., McDougal, Matthew B., Richardson, R. Blake, Schoggins, John W.
Published in Nature communications (06.09.2018)
Published in Nature communications (06.09.2018)
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LY6E impairs coronavirus fusion and confers immune control of viral disease
Pfaender, Stephanie, Mar, Katrina B., Michailidis, Eleftherios, Kratzel, Annika, Boys, Ian N., V’kovski, Philip, Fan, Wenchun, Kelly, Jenna N., Hirt, Dagny, Ebert, Nadine, Stalder, Hanspeter, Kleine-Weber, Hannah, Hoffmann, Markus, Hoffmann, Hans-Heinrich, Saeed, Mohsan, Dijkman, Ronald, Steinmann, Eike, Wight-Carter, Mary, McDougal, Matthew B., Hanners, Natasha W., Pöhlmann, Stefan, Gallagher, Tom, Todt, Daniel, Zimmer, Gert, Rice, Charles M., Schoggins, John W., Thiel, Volker
Published in Nature microbiology (01.11.2020)
Published in Nature microbiology (01.11.2020)
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Journal Article
Evolution of STAT2 resistance to flavivirus NS5 occurred multiple times despite genetic constraints
Veit, Ethan C., Salim, Madihah S., Jung, Mariel J., Richardson, R. Blake, Boys, Ian N., Quinlan, Meghan, Barrall, Erika A., Bednarski, Eva, Hamilton, Rachael E., Kikawa, Caroline, Elde, Nels C., García-Sastre, Adolfo, Evans, Matthew J.
Published in Nature communications (26.06.2024)
Published in Nature communications (26.06.2024)
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Development of a mutant aerosolized ACE2 that neutralizes SARS-CoV-2 in vivo
Kober, Daniel L, Caballero Van Dyke, Marley C, Eitson, Jennifer L, Boys, Ian N, McDougal, Matthew B, Rosenbaum, Daniel M, Schoggins, John W
Published in mBio (12.06.2024)
Published in mBio (12.06.2024)
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FDA approved drugs with antiviral activity against SARS-CoV-2: From structure-based repurposing to host-specific mechanisms
Ahmed, Mahmoud S., Farag, Ayman B., Boys, Ian N., Wang, Ping, Menendez-Montes, Ivan, Nguyen, Ngoc Uyen Nhi, Eitson, Jennifer L., Ohlson, Maikke B., Fan, Wenchun, McDougal, Matthew B., Mar, Katrina, Thet, Suwannee, Ortiz, Francisco, Kim, Soo Young, Solmonson, Ashley, Williams, Noelle S., Lemoff, Andrew, DeBerardinis, Ralph J., Schoggins, John W., Sadek, Hesham A.
Published in Biomedicine & pharmacotherapy (01.06.2023)
Published in Biomedicine & pharmacotherapy (01.06.2023)
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RTP4 Is a Potent IFN-Inducible Anti-flavivirus Effector Engaged in a Host-Virus Arms Race in Bats and Other Mammals
Boys, Ian N., Xu, Elaine, Mar, Katrina B., De La Cruz-Rivera, Pamela C., Eitson, Jennifer L., Moon, Benjamin, Schoggins, John W.
Published in Cell host & microbe (11.11.2020)
Published in Cell host & microbe (11.11.2020)
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Evolution of the interferon response: lessons from ISGs of diverse mammals
McDougal, Matthew B, Boys, Ian N, De La Cruz-Rivera, Pamela, Schoggins, John W
Published in Current opinion in virology (01.04.2022)
Published in Current opinion in virology (01.04.2022)
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Shiftless inhibits flavivirus replication in vitro and is neuroprotective in a mouse model of Zika virus pathogenesis
Hanners, Natasha W., Mar, Katrina B., Boys, Ian N., Eitson, Jennifer L., Cruz-Rivera, Pamela C. De La, Richardson, R. Blake, Fan, Wenchun, Wight-Carter, Mary, Schoggins, John W.
Published in Proceedings of the National Academy of Sciences - PNAS (07.12.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (07.12.2021)
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A CRISPR screen identifies IFI6 as an ER-resident interferon effector that blocks flavivirus replication
Richardson, R. Blake, Ohlson, Maikke B., Eitson, Jennifer L., Kumar, Ashwani, McDougal, Matthew B., Boys, Ian N., Mar, Katrina B., De La Cruz-Rivera, Pamela C., Douglas, Connor, Konopka, Genevieve, Xing, Chao, Schoggins, John W.
Published in Nature microbiology (01.11.2018)
Published in Nature microbiology (01.11.2018)
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Structural homology screens reveal poxvirus-encoded proteins impacting inflammasome-mediated defenses
Boys, Ian N, Johnson, Alex G, Quinlan, Meghan, Kranzusch, Philip J, Elde, Nels C
Published in bioRxiv (03.04.2023)
Published in bioRxiv (03.04.2023)
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Identification of FDA Approved Drugs with Antiviral Activity against SARS-CoV-2: A Tale from structure-based drug repurposing to host-cell mechanistic investigation
Ahmed, Mahmoud S., Farag, Ayman B., Boys, Ian N., Wang, Ping, Menendez-Montes, Ivan, Nguyen, Ngoc Uyen Nhi, Eitson, Jennifer L., Ohlson, Maikke B., Fan, Wenchun, McDougal, Matthew B., Mar, Katrina, Thet, Suwannee, Ortiz, Francisco, Kim, Soo Young, Solmonson, Ashley, Williams, Noelle S., Lemoff, Andrew, DeBerardinis, Ralph J., Schoggins, John W., Sadek, Hesham A.
Published in Biomedicine & pharmacotherapy (28.03.2023)
Published in Biomedicine & pharmacotherapy (28.03.2023)
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IFIT1 is rapidly evolving and exhibits disparate antiviral activities across 11 mammalian orders
McDougal, Matthew B, De Maria, Anthony M, Nakahara, Emi, Boys, Ian N, Schoggins, John W
Published in bioRxiv (12.07.2024)
Published in bioRxiv (12.07.2024)
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Journal Article
Development of a mutant aerosolized ACE2 that neutralizes SARS-CoV-2 in vivo
Kober, Daniel L, Caballero Van Dyke, Marley C, Eitson, Jennifer L, Boys, Ian N, McDougal, Matthew B, Rosenbaum, Daniel M, Schoggins, John W
Published in bioRxiv : the preprint server for biology (05.10.2023)
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Published in bioRxiv : the preprint server for biology (05.10.2023)
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