Image-based profiling for drug discovery: due for a machine-learning upgrade?
Chandrasekaran, Srinivas Niranj, Ceulemans, Hugo, Boyd, Justin D., Carpenter, Anne E.
Published in Nature reviews. Drug discovery (01.02.2021)
Published in Nature reviews. Drug discovery (01.02.2021)
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Familial knockin mutation of LRRK2 causes lysosomal dysfunction and accumulation of endogenous insoluble α-synuclein in neurons
Schapansky, Jason, Khasnavis, Saurabh, DeAndrade, Mark P., Nardozzi, Jonathan D., Falkson, Samuel R., Boyd, Justin D., Sanderson, John B., Bartels, Tim, Melrose, Heather L., LaVoie, Matthew J.
Published in Neurobiology of disease (01.03.2018)
Published in Neurobiology of disease (01.03.2018)
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Oxytocin alters cell fate selection of rat neural progenitor cells in vitro
Palanisamy, Arvind, Kannappan, Ramaswamy, Xu, Zhiqiang, Martino, Audrey, Friese, Matthew B, Boyd, Justin D, Crosby, Gregory, Culley, Deborah J
Published in PloS one (18.01.2018)
Published in PloS one (18.01.2018)
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Genomic DISC1 Disruption in hiPSCs Alters Wnt Signaling and Neural Cell Fate
Srikanth, Priya, Han, Karam, Callahan, Dana G., Makovkina, Eugenia, Muratore, Christina R., Lalli, Matthew A., Zhou, Honglin, Boyd, Justin D., Kosik, Kenneth S., Selkoe, Dennis J., Young-Pearse, Tracy L.
Published in Cell reports (Cambridge) (01.09.2015)
Published in Cell reports (Cambridge) (01.09.2015)
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Optimizing the Cell Painting assay for image-based profiling
Cimini, Beth A., Chandrasekaran, Srinivas Niranj, Kost-Alimova, Maria, Miller, Lisa, Goodale, Amy, Fritchman, Briana, Byrne, Patrick, Garg, Sakshi, Jamali, Nasim, Logan, David J., Concannon, John B., Lardeau, Charles-Hugues, Mouchet, Elizabeth, Singh, Shantanu, Shafqat Abbasi, Hamdah, Aspesi, Peter, Boyd, Justin D., Gilbert, Tamara, Gnutt, David, Hariharan, Santosh, Hernandez, Desiree, Hormel, Gisela, Juhani, Karolina, Melanson, Michelle, Mervin, Lewis H., Monteverde, Tiziana, Pilling, James E., Skepner, Adam, Swalley, Susanne E., Vrcic, Anita, Weisbart, Erin, Williams, Guy, Yu, Shan, Zapiec, Bolek, Carpenter, Anne E.
Published in Nature protocols (01.07.2023)
Published in Nature protocols (01.07.2023)
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VXX-401, a novel anti-PCSK9 vaccine, reduces LDL-C in cynomolgus monkeys
Vroom, Madeline M., Lu, Hanxin, Lewis, Maggie, Thibodeaux, Brett A., Brooks, Jeanne K., Longo, Matthew S., Ramos, Martina M., Sahni, Jaya, Wiggins, Jonathan, Boyd, Justin D., Wang, Shixia, Ding, Shuang, Hellerstein, Michael, Ryan, Valorie, Powchik, Peter, Dodart, Jean-Cosme
Published in Journal of lipid research (01.02.2024)
Published in Journal of lipid research (01.02.2024)
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A High Content Drug Screen Identifies Ursolic Acid as an Inhibitor of Amyloid β Protein Interactions with Its Receptor CD36
Wilkinson, Kim, Boyd, Justin D., Glicksman, Marcie, Moore, Kathryn J., El Khoury, Joseph
Published in The Journal of biological chemistry (07.10.2011)
Published in The Journal of biological chemistry (07.10.2011)
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A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants
Ryan, Katie J, White, Charles C, Patel, Kruti, Xu, Jishu, Olah, Marta, Replogle, Joseph M, Frangieh, Michael, Cimpean, Maria, Winn, Phoebe, McHenry, Allison, Kaskow, Belinda J, Chan, Gail, Cuerdon, Nicole, Bennett, David A, Boyd, Justin D, Imitola, Jaime, Elyaman, Wassim, De Jager, Philip L, Bradshaw, Elizabeth M
Published in Science translational medicine (20.12.2017)
Published in Science translational medicine (20.12.2017)
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Target engagement and immunogenicity of an active immunotherapeutic targeting pathological α-synuclein: a phase 1 placebo-controlled trial
Eijsvogel, Pepijn, Misra, Pinaki, Concha-Marambio, Luis, Boyd, Justin D., Ding, Shuang, Fedor, Lauren, Hsieh, Yueh-Ting, Sun, Yu Shuang, Vroom, Madeline M., Farris, Carly M., Ma, Yihua, de Kam, Marieke L., Radanovic, Igor, Vissers, Maurits F. J. M., Mirski, Dario, Shareghi, Ghazal, Shahnawaz, Mohammad, Singer, Wolfgang, Kremer, Philip, Groeneveld, Geert Jan, Yu, Hui Jing, Dodart, Jean-Cosme
Published in Nature medicine (01.09.2024)
Published in Nature medicine (01.09.2024)
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Prolonged Treatment with Propofol Transiently Impairs Proliferation but Not Survival of Rat Neural Progenitor Cells In Vitro
Palanisamy, Arvind, Friese, Matthew B, Cotran, Emily, Moller, Ludde, Boyd, Justin D, Crosby, Gregory, Culley, Deborah J
Published in PloS one (05.07.2016)
Published in PloS one (05.07.2016)
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Isoflurane Decreases Self-renewal Capacity of Rat Cultured Neural Stem Cells
CULLEY, Deborah J, BOYD, Justin D, PALANISAMY, Arvind, ZHONGCONG XIE, KOJIMA, Koji, VACANTI, Charles A, TANZI, Rudolph E, CROSBY, Gregory
Published in Anesthesiology (Philadelphia) (01.10.2011)
Published in Anesthesiology (Philadelphia) (01.10.2011)
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An in vitro paradigm to assess potential anti-Aβ antibodies for Alzheimer’s disease
Jin, Ming, O’Nuallain, Brian, Hong, Wei, Boyd, Justin, Lagomarsino, Valentina N., O’Malley, Tiernan T., Liu, Wen, Vanderburg, Charles R., Frosch, Matthew P., Young-Pearse, Tracy, Selkoe, Dennis J., Walsh, Dominic M.
Published in Nature communications (11.07.2018)
Published in Nature communications (11.07.2018)
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GW5074 Increases Microglial Phagocytic Activities: Potential Therapeutic Direction for Alzheimer's Disease
Connor, Sarah M, Rashid, Mamunur, Ryan, Katie J, Patel, Kruti, Boyd, Justin D, Smith, Jennifer, Elyaman, Wassim, Bennett, David A, Bradshaw, Elizabeth M
Published in Frontiers in cellular neuroscience (23.05.2022)
Published in Frontiers in cellular neuroscience (23.05.2022)
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Angiogenic factors stimulate growth of adult neural stem cells
Androutsellis-Theotokis, Andreas, Rueger, Maria A, Park, Deric M, Boyd, Justin D, Padmanabhan, Raji, Campanati, Loraine, Stewart, Craig V, LeFranc, Yann, Plenz, Dietmar, Walbridge, Stuart, Lonser, Russell R, McKay, Ronald D G
Published in PloS one (26.02.2010)
Published in PloS one (26.02.2010)
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Society of Biomolecular Imaging and Informatics High-Content Screening/High-Content Analysis Preclinical Translational Imaging Colloquium: How Emerging Technologies in Disease Models, High-Content Imaging, and Data Analytics Are Changing Our Approach to Drug Discovery
Boyd, Justin D, Hoffman, Ann F, Gebhard, David
Published in Assay and drug development technologies (01.01.2019)
Published in Assay and drug development technologies (01.01.2019)
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A high-content screen identifies novel compounds that inhibit stress-induced TDP-43 cellular aggregation and associated cytotoxicity
Boyd, Justin D, Lee, Peter, Feiler, Marisa S, Zauur, Nava, Liu, Min, Concannon, John, Ebata, Atsushi, Wolozin, Benjamin, Glicksman, Marcie A
Published in Journal of biomolecular screening (01.01.2014)
Published in Journal of biomolecular screening (01.01.2014)
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A new means to identify type 3 secreted effectors: functionally interchangeable class IB chaperones recognize a conserved sequence
Costa, Sonia C P, Schmitz, Alexa M, Jahufar, Fathima F, Boyd, Justin D, Cho, Min Y, Glicksman, Marcie A, Lesser, Cammie F
Published in mBio (01.01.2012)
Published in mBio (01.01.2012)
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