Stereoselective Conjugate Addition Reactions Using In Situ Metallated Terminal Alkynes and the Development of Novel Chiral P,N-Ligands
Fujimori, Shinji, Knöpfel, Thomas F, Zarotti, Pablo, Ichikawa, Takashi, Boyall, Dean, Carreira, Erick M
Published in Bulletin of the Chemical Society of Japan (15.09.2007)
Published in Bulletin of the Chemical Society of Japan (15.09.2007)
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Preparation of cyclic ethers for polyether synthesis by catalytic ring-closing enyne metathesis of alkynyl ethers
Stephen Clark, J, Elustondo, Frédéric, Trevitt, Graham P, Boyall, Dean, Robertson, Jerod, Blake, Alexander J, Wilson, Claire, Stammen, Blanda
Published in Tetrahedron (04.03.2002)
Published in Tetrahedron (04.03.2002)
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New 4‐Amino‐1,2,3‐Triazole Inhibitors of Indoleamine 2,3‐Dioxygenase Form a Long‐Lived Complex with the Enzyme and Display Exquisite Cellular Potency
Alexandre, Julie Anne Christine, Swan, Michael Kenneth, Latchem, Mike John, Boyall, Dean, Pollard, John Robert, Hughes, Stuart Wynn, Westcott, James
Published in Chembiochem : a European journal of chemical biology (16.03.2018)
Published in Chembiochem : a European journal of chemical biology (16.03.2018)
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Cover Feature: New 4‐Amino‐1,2,3‐Triazole Inhibitors of Indoleamine 2,3‐Dioxygenase Form a Long‐Lived Complex with the Enzyme and Display Exquisite Cellular Potency (ChemBioChem 6/2018)
Alexandre, Julie Anne Christine, Swan, Michael Kenneth, Latchem, Mike John, Boyall, Dean, Pollard, John Robert, Hughes, Stuart Wynn, Westcott, James
Published in Chembiochem : a European journal of chemical biology (16.03.2018)
Published in Chembiochem : a European journal of chemical biology (16.03.2018)
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Journal Article
Design and Optimization of Selective Protein Kinase C θ (PKCθ) Inhibitors for the Treatment of Autoimmune Diseases
Jimenez, Juan-Miguel, Boyall, Dean, Brenchley, Guy, Collier, Philip N, Davis, Christopher J, Fraysse, Damien, Keily, Shazia B, Henderson, Jaclyn, Miller, Andrew, Pierard, Francoise, Settimo, Luca, Twin, Heather C, Bolton, Claire M, Curnock, Adam P, Chiu, Peter, Tanner, Adam J, Young, Stephen
Published in Journal of medicinal chemistry (14.03.2013)
Published in Journal of medicinal chemistry (14.03.2013)
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Discovery of Selective, Orally Bioavailable Pyrazolopyridine Inhibitors of Protein Kinase Cθ (PKCθ) That Ameliorate Symptoms of Experimental Autoimmune Encephalomyelitis
Collier, Philip N, Twin, Heather C, Knegtel, Ronald M. A, Boyall, Dean, Brenchley, Guy, Davis, Christopher J, Keily, Shazia, Mak, Chau, Miller, Andrew, Pierard, Françoise, Settimo, Luca, Bolton, Clare M, Chiu, Peter, Curnock, Adam, Doyle, Elisabeth, Tanner, Adam J, Jimenez, Juan-Miguel
Published in ACS medicinal chemistry letters (08.08.2019)
Published in ACS medicinal chemistry letters (08.08.2019)
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Structure-based optimization of aminopyridines as PKCθ inhibitors
Jimenez, Juan-Miguel, Davis, Christopher, Boyall, Dean, Fraysse, Damien, Knegtel, Ronald, Settimo, Luca, Young, Stephen, Bolton, Claire, Chiu, Peter, Curnock, Adam, Rasmussen, Richele, Tanner, Adam, Ager, Ian
Published in Bioorganic & medicinal chemistry letters (15.07.2012)
Published in Bioorganic & medicinal chemistry letters (15.07.2012)
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PYRAZOLOPYRIDINE KINASE INHIBITORS
BOYALL DEAN, SETTIMO LUCA, DAMIEN FRAYSSE, JIMENEZ JUAN-MIGUEL, GUY BRENCHLEY
Year of Publication 18.12.2014
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Year of Publication 18.12.2014
Patent
TRICYCLIC PYRAZOLO-PYRIDINE KINASE INHIBITOR
BOYALL DEAN, SETTIMO LUCA, DAMIEN FRAYSSE, JIMENEZ JUAN-MIGUEL, GUY BRENCHLEY
Year of Publication 06.11.2014
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Year of Publication 06.11.2014
Patent
COMPOUNDS USEFUL AS INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE
WEBER PETER, EVERITT SIMON, BOYALL DEAN, MILLER ANDREW, WESTCOTT JAMES, YOUNG STEPHEN, SETTIMO LUCA, DODD JAMES, DAVIS CHRISTOPHER
Year of Publication 29.07.2015
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Year of Publication 29.07.2015
Patent
2-AMINOPYRIDINE DERIVATIVES USEFUL AS KINASE INHIBITORS
MAKTAIS FRANCOIS, MORTIMORE MICHAEL, DAVIS CHRIS, BOYALL DEAN, BEMIS GUY, SETTIMO LUCA, YOUNG STEVEN, JUAN-MIGUEL JIMENEZ, WANG TIANSHENG, KNEGTEL RONALD, FRAYSSE DAMIEN
Year of Publication 05.02.2015
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Year of Publication 05.02.2015
Patent
TRICYCLIC PYRAZOLO-PYRIDINE KINASE INHIBITOR
PHILIP COLLIER, DAVIS CHRIS, BOYALL DEAN, MILLER ANDREW, SETTIMO LUCA, DAMIEN FRAYSSE, JOHN STUDLEY, JIMENEZ JUAN-MIGUEL, YOUNG STEVEN, KNEGTEL RONALD, GUY BRENCHLEY, HEATHER TWIN
Year of Publication 06.11.2014
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Year of Publication 06.11.2014
Patent
PYRAZOLOPYRIDINE KINASE INHIBITORS
BOYALL DEAN, JIMENEZ JUAN MIGUEL, SETTIMO LUCA, BRENCHLEY GUY, FRAYSSE DAMIEN
Year of Publication 19.04.2011
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Year of Publication 19.04.2011
Patent
COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE
SHAW DAVID, BOYALL DEAN, ETXEBARRIA I JARDI GORKA, MIDDLETON DONALD, STORCK PIERRE HENRI, TWIN HEATHER, PANESAR MANINDER, DURRANT STEVEN, ODONNELL MICHAEL, PIERARD FRANCOISE, KAY DAVID, DAVIS CHRIS, CHARRIER JEAN DAMIEN, JIMENEZ JUAN MIGUEL, STUDLEY JOHN, PINDER JOANNE, KNEGTEL RONALD, DAVIS REBECCA, FRAYSSE DAMIEN, AHMAD NADIA
Year of Publication 07.08.2015
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Year of Publication 07.08.2015
Patent
AZAINDOLE USEFUL AS JAK AND OTHER PROTEIN KINASE INHIBITOR
EVERITT SIMON, BOYALL DEAN, BETHIEL RANDY, COME JON, LAUFFER DAVID, SALITURO FRANCESCO, ROBINSON DANIEL, HARRINGTON EDMUND, BINCH HAYLEY, FARMER LUC, MORTIMORE MICHAEL, WANG JIAN, ARONOV ALEX, PIERARD FRANCOISE, PIERCE ALBERT, GREEN JEREMY, CHARRIER JEAN-DAMIEN, COURT JOHN, PINDER JOANNE, WANG TIANSHENG, FRAYSSE DAMIEN
Year of Publication 22.06.2015
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Year of Publication 22.06.2015
Patent
TRI-CYCLIC PYRAZOLOPYRIDINE KINASE INHIBITORS
DAVIS CHRIS, BOYALL DEAN, JIMENEZ JUAN MIGUEL, MILLER ANDREW, YOUNG STEPHEN, SETTIMO LUCA, STUDLEY JOHN, BRENCHLEY GUY, TWIN HEATHER, KNEGTEL RONALD, FRAYSSE DAMIEN, COLLIER PHILIP
Year of Publication 30.03.2011
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Year of Publication 30.03.2011
Patent