Manganese Is Essential for Neuronal Health
Horning, Kyle J, Caito, Samuel W, Tipps, K. Grace, Bowman, Aaron B, Aschner, Michael
Published in Annual review of nutrition (17.07.2015)
Published in Annual review of nutrition (17.07.2015)
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Journal Article
Brain manganese and the balance between essential roles and neurotoxicity
Balachandran, Rekha C., Mukhopadhyay, Somshuvra, McBride, Danielle, Veevers, Jennifer, Harrison, Fiona E., Aschner, Michael, Haynes, Erin N., Bowman, Aaron B.
Published in The Journal of biological chemistry (08.05.2020)
Published in The Journal of biological chemistry (08.05.2020)
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Journal Article
Manganese homeostasis in the nervous system
Chen, Pan, Chakraborty, Sudipta, Mukhopadhyay, Somshuvra, Lee, Eunsook, Paoliello, Monica M. B., Bowman, Aaron B., Aschner, Michael
Published in Journal of neurochemistry (01.08.2015)
Published in Journal of neurochemistry (01.08.2015)
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Journal Article
SLC30A10 is a cell surface-localized manganese efflux transporter, and parkinsonism-causing mutations block its intracellular trafficking and efflux activity
Leyva-Illades, Dinorah, Chen, Pan, Zogzas, Charles E, Hutchens, Steven, Mercado, Jonathan M, Swaim, Caleb D, Morrisett, Richard A, Bowman, Aaron B, Aschner, Michael, Mukhopadhyay, Somshuvra
Published in The Journal of neuroscience (15.10.2014)
Published in The Journal of neuroscience (15.10.2014)
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Journal Article
"Manganese-induced neurotoxicity: a review of its behavioral consequences and neuroprotective strategies"
Peres, Tanara V, Schettinger, Maria Rosa C, Chen, Pan, Carvalho, Fabiano, Avila, Daiana S, Bowman, Aaron B, Aschner, Michael
Published in BMC pharmacology & toxicology (04.11.2016)
Published in BMC pharmacology & toxicology (04.11.2016)
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Journal Article
Role of astrocytes in brain function and disease
Sidoryk-Wegrzynowicz, Marta, Wegrzynowicz, Michal, Lee, Eunsook, Bowman, Aaron B, Aschner, Michael
Published in Toxicologic pathology (01.01.2011)
Published in Toxicologic pathology (01.01.2011)
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Journal Article
A Simplified, Fully Defined Differentiation Scheme for Producing Blood-Brain Barrier Endothelial Cells from Human iPSCs
Neal, Emma H, Marinelli, Nicholas A, Shi, Yajuan, McClatchey, P Mason, Balotin, Kylie M, Gullett, Dalton R, Hagerla, Kameron A, Bowman, Aaron B, Ess, Kevin C, Wikswo, John P, Lippmann, Ethan S
Published in Stem cell reports (11.06.2019)
Published in Stem cell reports (11.06.2019)
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Journal Article
Molecular Targets of Manganese-Induced Neurotoxicity: A Five-Year Update
Tinkov, Alexey A, Paoliello, Monica M B, Mazilina, Aksana N, Skalny, Anatoly V, Martins, Airton C, Voskresenskaya, Olga N, Aaseth, Jan, Santamaria, Abel, Notova, Svetlana V, Tsatsakis, Aristides, Lee, Eunsook, Bowman, Aaron B, Aschner, Michael
Published in International journal of molecular sciences (28.04.2021)
Published in International journal of molecular sciences (28.04.2021)
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Journal Article
Accelerated differentiation of human induced pluripotent stem cells to blood-brain barrier endothelial cells
Hollmann, Emma K, Bailey, Amanda K, Potharazu, Archit V, Neely, M Diana, Bowman, Aaron B, Lippmann, Ethan S
Published in Fluids and barriers of the CNS (13.04.2017)
Published in Fluids and barriers of the CNS (13.04.2017)
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Journal Article
The antioxidant role of STAT3 in methylmercury-induced toxicity in mouse hypothalamic neuronal GT1-7 cell line
Ferrer, Beatriz, Suresh, Harshini, Santamaria, Abel, Rocha, João Batista, Bowman, Aaron B., Aschner, Michael
Published in Free radical biology & medicine (01.08.2021)
Published in Free radical biology & medicine (01.08.2021)
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Journal Article
Recreating blood-brain barrier physiology and structure on chip: A novel neurovascular microfluidic bioreactor
Brown, Jacquelyn A, Pensabene, Virginia, Markov, Dmitry A, Allwardt, Vanessa, Neely, M Diana, Shi, Mingjian, Britt, Clayton M, Hoilett, Orlando S, Yang, Qing, Brewer, Bryson M, Samson, Philip C, McCawley, Lisa J, May, James M, Webb, Donna J, Li, Deyu, Bowman, Aaron B, Reiserer, Ronald S, Wikswo, John P
Published in Biomicrofluidics (01.09.2015)
Published in Biomicrofluidics (01.09.2015)
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Journal Article
Defective Mitochondrial Dynamics Underlie Manganese-Induced Neurotoxicity
Morcillo, Patricia, Cordero, Hector, Ijomone, Omamuyovwi M., Ayodele, Akinyemi, Bornhorst, Julia, Gunther, Leslie, Macaluso, Frank P., Bowman, Aaron B., Aschner, Michael
Published in Molecular neurobiology (01.07.2021)
Published in Molecular neurobiology (01.07.2021)
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Journal Article
Ascorbate deficiency decreases dopamine release in gulo–/– and APP/PSEN1 mice
Consoli, David C., Brady, Lillian J., Bowman, Aaron B., Calipari, Erin S., Harrison, Fiona E.
Published in Journal of neurochemistry (01.05.2021)
Published in Journal of neurochemistry (01.05.2021)
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Journal Article
Metabolic consequences of inflammatory disruption of the blood-brain barrier in an organ-on-chip model of the human neurovascular unit
Brown, Jacquelyn A, Codreanu, Simona G, Shi, Mingjian, Sherrod, Stacy D, Markov, Dmitry A, Neely, M Diana, Britt, Clayton M, Hoilett, Orlando S, Reiserer, Ronald S, Samson, Philip C, McCawley, Lisa J, Webb, Donna J, Bowman, Aaron B, McLean, John A, Wikswo, John P
Published in Journal of neuroinflammation (12.12.2016)
Published in Journal of neuroinflammation (12.12.2016)
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Journal Article
Alterations in metal homeostasis occur prior to canonical markers in Huntington disease
Pfalzer, Anna C., Yan, Yan, Kang, Hakmook, Totten, Melissa, Silverman, James, Bowman, Aaron B., Erikson, Keith, Claassen, Daniel O.
Published in Scientific reports (20.06.2022)
Published in Scientific reports (20.06.2022)
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Hyperexcitability and Pharmacological Responsiveness of Cortical Neurons Derived from Human iPSCs Carrying Epilepsy-Associated Sodium Channel Nav1.2-L1342P Genetic Variant
Que, Zhefu, Olivero-Acosta, Maria I, Zhang, Jingliang, Eaton, Muriel, Tukker, Anke M, Chen, Xiaoling, Wu, Jiaxiang, Xie, Junkai, Xiao, Tiange, Wettschurack, Kyle, Yunis, Layan, Shafer, J Marshall, Schaber, James A, Rochet, Jean-Christophe, Bowman, Aaron B, Yuan, Chongli, Huang, Zhuo, Hu, Chang-Deng, Trader, Darci J, Skarnes, William C, Yang, Yang
Published in The Journal of neuroscience (08.12.2021)
Published in The Journal of neuroscience (08.12.2021)
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Journal Article
Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1
Zoghbi, Huda Y, Lim, Janghoo, Crespo-Barreto, Juan, Jafar-Nejad, Paymaan, Bowman, Aaron B, Richman, Ronald, Hill, David E, Orr, Harry T
Published in Nature (10.04.2008)
Published in Nature (10.04.2008)
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Post-translational modifications in MeHg-induced neurotoxicity
Ke, Tao, Gonçalves, Filipe Marques, Gonçalves, Cinara Ludvig, dos Santos, Alessandra Antunes, Rocha, João B.T., Farina, Marcelo, Skalny, Anatoly, Tsatsakis, Aristidis, Bowman, Aaron B., Aschner, Michael
Published in Biochimica et biophysica acta. Molecular basis of disease (01.08.2019)
Published in Biochimica et biophysica acta. Molecular basis of disease (01.08.2019)
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Defective Sphingosine-1-phosphate metabolism is a druggable target in Huntington’s disease
Di Pardo, Alba, Amico, Enrico, Basit, Abdul, Armirotti, Andrea, Joshi, Piyush, Neely, M. Diana, Vuono, Romina, Castaldo, Salvatore, Digilio, Anna F., Scalabrì, Francesco, Pepe, Giuseppe, Elifani, Francesca, Madonna, Michele, Jeong, Se Kyoo, Park, Bu-Mahn, D’Esposito, Maurizio, Bowman, Aaron B., Barker, Roger A., Maglione, Vittorio
Published in Scientific reports (13.07.2017)
Published in Scientific reports (13.07.2017)
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