The role of immune dysfunction in obesity-associated cancer risk, progression, and metastasis
Kulkarni, Aneesha, Bowers, Laura W.
Published in Cellular and molecular life sciences : CMLS (01.04.2021)
Published in Cellular and molecular life sciences : CMLS (01.04.2021)
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Journal Article
Signals from the Adipose Microenvironment and the Obesity-Cancer Link-A Systematic Review
Himbert, Caroline, Delphan, Mahmoud, Scherer, Dominique, Bowers, Laura W, Hursting, Stephen, Ulrich, Cornelia M
Published in Cancer prevention research (Philadelphia, Pa.) (01.09.2017)
Published in Cancer prevention research (Philadelphia, Pa.) (01.09.2017)
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Journal Article
The Role of the Insulin/IGF System in Cancer: Lessons Learned from Clinical Trials and the Energy Balance-Cancer Link
Bowers, Laura W, Rossi, Emily L, O'Flanagan, Ciara H, deGraffenried, Linda A, Hursting, Stephen D
Published in Frontiers in endocrinology (Lausanne) (15.05.2015)
Published in Frontiers in endocrinology (Lausanne) (15.05.2015)
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Journal Article
Leptin Signaling Mediates Obesity-Associated CSC Enrichment and EMT in Preclinical TNBC Models
Bowers, Laura W, Rossi, Emily L, McDonell, Shannon B, Doerstling, Steven S, Khatib, Subreen A, Lineberger, Claire G, Albright, Jody E, Tang, Xiaohu, deGraffenried, Linda A, Hursting, Stephen D
Published in Molecular cancer research (01.05.2018)
Published in Molecular cancer research (01.05.2018)
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Journal Article
NSAID Use Reduces Breast Cancer Recurrence in Overweight and Obese Women: Role of Prostaglandin-Aromatase Interactions
BOWERS, Laura W, MAXIMO, Ilane X. F, BRENNER, Andrew J, BEERAM, Muralidhar, HURSTING, Stephen D, PRICE, Ramona S, TEKMAL, Rajeshwar R, JOLLY, Christopher A, DEGRAFFENRIED, Linda A
Published in Cancer research (Chicago, Ill.) (15.08.2014)
Published in Cancer research (Chicago, Ill.) (15.08.2014)
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Journal Article
Obesity-associated systemic interleukin-6 promotes pre-adipocyte aromatase expression via increased breast cancer cell prostaglandin E2 production
Bowers, Laura W., Brenner, Andrew J., Hursting, Stephen D., Tekmal, Rajeshwar R., deGraffenried, Linda A.
Published in Breast cancer research and treatment (01.01.2015)
Published in Breast cancer research and treatment (01.01.2015)
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Journal Article
Separate and combined effects of advanced age and obesity on mammary adipose inflammation, immunosuppression and tumor progression in mouse models of triple negative breast cancer
Smith, Laura A, Craven, Dalton M, Rainey, Magdalena A, Cozzo, Alyssa J, Carson, Meredith S, Glenny, Elaine M, Sheth, Nishita, McDonell, Shannon B, Rezeli, Erika T, Montgomery, Stephanie A, Bowers, Laura W, Coleman, Michael F, Hursting, Stephen D
Published in Frontiers in oncology (04.01.2023)
Published in Frontiers in oncology (04.01.2023)
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Journal Article
Calorie restriction outperforms bariatric surgery in a murine model of obesity and triple-negative breast cancer
Camp, Kristina K, Coleman, Michael F, McFarlane, Tori L, Doerstling, Steven S, Khatib, Subreen A, Rezeli, Erika T, Lewis, Alfor G, Pfeil, Alexander J, Smith, Laura A, Bowers, Laura W, Fouladi, Farnaz, Gong, Weida, Glenny, Elaine M, Parker, Joel S, Milne, Ginger L, Carroll, Ian M, Fodor, Anthony A, Seeley, Randy J, Hursting, Stephen D
Published in JCI insight (12.09.2023)
Published in JCI insight (12.09.2023)
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Journal Article
The flaxseed lignan secoisolariciresinol diglucoside decreases local inflammation, suppresses NFκB signaling, and inhibits mammary tumor growth
Bowers, Laura W., Lineberger, Claire G., Ford, Nikki A., Rossi, Emily L., Punjala, Arunima, Camp, Kristina K., Kimler, Bruce K., Fabian, Carol J., Hursting, Stephen D.
Published in Breast cancer research and treatment (01.02.2019)
Published in Breast cancer research and treatment (01.02.2019)
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Journal Article
Reversing the Genomic, Epigenetic, and Triple-Negative Breast Cancer-Enhancing Effects of Obesity
Bowers, Laura W, Doerstling, Steven S, Shamsunder, Meghana G, Lineberger, Claire G, Rossi, Emily L, Montgomery, Stephanie A, Coleman, Michael F, Gong, Weida, Parker, Joel S, Howell, Anthony, Harvie, Michelle, Hursting, Stephen D
Published in Cancer prevention research (Philadelphia, Pa.) (01.09.2022)
Published in Cancer prevention research (Philadelphia, Pa.) (01.09.2022)
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Journal Article
Resveratrol inhibits obesity‐associated adipose tissue dysfunction and tumor growth in a mouse model of postmenopausal claudin‐low breast cancer
Rossi, Emily L., Khatib, Subreen A., Doerstling, Steven S., Bowers, Laura W., Pruski, Melissa, Ford, Nikki A., Glickman, Randolph D., Niu, Mengmeng, Yang, Peiying, Cui, Zhengrong, DiGiovanni, John, Hursting, Stephen D.
Published in Molecular carcinogenesis (01.03.2018)
Published in Molecular carcinogenesis (01.03.2018)
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Journal Article
Weight Loss and/or Sulindac Mitigate Obesity-associated Transcriptome, Microbiome, and Protumor Effects in a Murine Model of Colon Cancer
Bowers, Laura W, Glenny, Elaine M, Punjala, Arunima, Lanman, Nadia A, Goldbaum, Audrey, Himbert, Caroline, Montgomery, Stephanie A, Yang, Peiying, Roper, Jatin, Ulrich, Cornelia M, Dannenberg, Andrew J, Coleman, Michael F, Hursting, Stephen D
Published in Cancer prevention research (Philadelphia, Pa.) (01.08.2022)
Published in Cancer prevention research (Philadelphia, Pa.) (01.08.2022)
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Journal Article
Energy Balance Modulation Impacts Epigenetic Reprogramming, ERα and ERβ Expression, and Mammary Tumor Development in MMTV-neu Transgenic Mice
Rossi, Emily L, Dunlap, Sarah M, Bowers, Laura W, Khatib, Subreen A, Doerstling, Steven S, Smith, Laura A, Ford, Nikki A, Holley, Darcy, Brown, Powel H, Estecio, Marcos R, Kusewitt, Donna F, deGraffenried, Linda A, Bultman, Scott J, Hursting, Stephen D
Published in Cancer research (Chicago, Ill.) (01.05.2017)
Published in Cancer research (Chicago, Ill.) (01.05.2017)
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Journal Article
Multi-omics Analysis Reveals Adipose-tumor Crosstalk in Patients with Colorectal Cancer
Holowatyj, Andreana N, Haffa, Mariam, Lin, Tengda, Scherer, Dominique, Gigic, Biljana, Ose, Jennifer, Warby, Christy A, Himbert, Caroline, Abbenhardt-Martin, Clare, Achaintre, David, Boehm, Juergen, Boucher, Kenneth M, Gicquiau, Audrey, Gsur, Andrea, Habermann, Nina, Herpel, Esther, Kauczor, Hans-Ulrich, Keski-Rahkonen, Pekka, Kloor, Matthias, von Knebel-Doeberitz, Magnus, Kok, Dieuwertje E, Nattenmüller, Johanna, Schirmacher, Peter, Schneider, Martin, Schrotz-King, Petra, Simon, Thomas, Ueland, Per M, Viskochil, Richard, Weijenberg, Matty P, Scalbert, Augustin, Ulrich, Alexis, Bowers, Laura W, Hursting, Stephen D, Ulrich, Cornelia M
Published in Cancer prevention research (Philadelphia, Pa.) (01.10.2020)
Published in Cancer prevention research (Philadelphia, Pa.) (01.10.2020)
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Journal Article
Obesity-Associated Alterations in Inflammation, Epigenetics, and Mammary Tumor Growth Persist in Formerly Obese Mice
Rossi, Emily L, de Angel, Rebecca E, Bowers, Laura W, Khatib, Subreen A, Smith, Laura A, Van Buren, Eric, Bhardwaj, Priya, Giri, Dilip, Estecio, Marcos R, Troester, Melissa A, Hair, Brionna Y, Kirk, Erin L, Gong, Ting, Shen, Jianjun, Dannenberg, Andrew J, Hursting, Stephen D
Published in Cancer prevention research (Philadelphia, Pa.) (01.05.2016)
Published in Cancer prevention research (Philadelphia, Pa.) (01.05.2016)
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Journal Article
Abstract 4321: The pro-tumorigenic effects of obesity are reversed by severe weight loss via chronic or intermittent calorie restriction but not weight normalization via a low-fat diet
Bowers, Laura W., Rossi, Emily L., Shamsunder, Meghana G., Hursting, Stephen D.
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
A weighty problem: metabolic perturbations and the obesity-cancer link
O’Flanagan, Ciara H., Bowers, Laura W., Hursting, Stephen D.
Published in Hormone molecular biology and clinical investigation (01.08.2015)
Published in Hormone molecular biology and clinical investigation (01.08.2015)
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Journal Article