Efficient Ablation of Genes in Human Hematopoietic Stem and Effector Cells using CRISPR/Cas9
Mandal, Pankaj K., Ferreira, Leonardo M.R., Collins, Ryan, Meissner, Torsten B., Boutwell, Christian L., Friesen, Max, Vrbanac, Vladimir, Garrison, Brian S., Stortchevoi, Alexei, Bryder, David, Musunuru, Kiran, Brand, Harrison, Tager, Andrew M., Allen, Todd M., Talkowski, Michael E., Rossi, Derrick J., Cowan, Chad A.
Published in Cell stem cell (06.11.2014)
Published in Cell stem cell (06.11.2014)
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Highly sensitive and specific detection of rare variants in mixed viral populations from massively parallel sequence data
Macalalad, Alexander R, Zody, Michael C, Charlebois, Patrick, Lennon, Niall J, Newman, Ruchi M, Malboeuf, Christine M, Ryan, Elizabeth M, Boutwell, Christian L, Power, Karen A, Brackney, Doug E, Pesko, Kendra N, Levin, Joshua Z, Ebel, Gregory D, Allen, Todd M, Birren, Bruce W, Henn, Matthew R
Published in PLoS computational biology (01.03.2012)
Published in PLoS computational biology (01.03.2012)
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Reduced Viral Replication Capacity of Human Immunodeficiency Virus Type 1 Subtype C Caused by Cytotoxic-T-Lymphocyte Escape Mutations in HLA-B57 Epitopes of Capsid Protein
BOUTWELL, Christian L, ROWLEY, Christopher F, ESSEX, M
Published in Journal of Virology (15.03.2009)
Published in Journal of Virology (15.03.2009)
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Innate Immune Reconstitution in Humanized Bone Marrow-Liver-Thymus (HuBLT) Mice Governs Adaptive Cellular Immune Function and Responses to HIV-1 Infection
Garcia-Beltran, Wilfredo F, Claiborne, Daniel T, Maldini, Colby R, Phelps, Meredith, Vrbanac, Vladimir, Karpel, Marshall E, Krupp, Katharine L, Power, Karen A, Boutwell, Christian L, Balazs, Alejandro B, Tager, Andrew M, Altfeld, Marcus, Allen, Todd M
Published in Frontiers in immunology (26.05.2021)
Published in Frontiers in immunology (26.05.2021)
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Viral Evolution and Escape during Acute HIV-1 Infection
Boutwell, Christian L., Rolland, Morgane M., Herbeck, Joshua T., Mullins, James I., Allen, Todd M.
Published in The Journal of infectious diseases (15.10.2010)
Published in The Journal of infectious diseases (15.10.2010)
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Conference Proceeding
Frequent and Variable Cytotoxic-T-Lymphocyte Escape-Associated Fitness Costs in the Human Immunodeficiency Virus Type 1 Subtype B Gag Proteins
Boutwell, Christian L, Carlson, Jonathan M, Lin, Tien-Ho, Seese, Aaron, Power, Karen A, Peng, Jian, Tang, Yanhua, Brumme, Zabrina L, Heckerman, David, Schneidewind, Arne, Allen, Todd M
Published in Journal of Virology (01.04.2013)
Published in Journal of Virology (01.04.2013)
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Complete viral RNA genome sequencing of ultra-low copy samples by sequence-independent amplification
Malboeuf, Christine M., Yang, Xiao, Charlebois, Patrick, Qu, James, Berlin, Aaron M., Casali, Monica, Pesko, Kendra N., Boutwell, Christian L., DeVincenzo, John P., Ebel, Gregory D., Allen, Todd M., Zody, Michael C., Henn, Matthew R., Levin, Joshua Z.
Published in Nucleic acids research (01.01.2013)
Published in Nucleic acids research (01.01.2013)
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Dual CD4-based CAR T cells with distinct costimulatory domains mitigate HIV pathogenesis in vivo
Maldini, Colby R, Claiborne, Daniel T, Okawa, Ken, Chen, Tao, Dopkin, Derrick L, Shan, Xiaochuan, Power, Karen A, Trifonova, Radiana T, Krupp, Katharine, Phelps, Meredith, Vrbanac, Vladimir D, Tanno, Serah, Bateson, Timothy, Leslie, George J, Hoxie, James A, Boutwell, Christian L, Riley, James L, Allen, Todd M
Published in Nature medicine (01.11.2020)
Published in Nature medicine (01.11.2020)
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BLT humanized mice as a small animal model of HIV infection
Karpel, Marshall E, Boutwell, Christian L, Allen, Todd M
Published in Current opinion in virology (01.08.2015)
Published in Current opinion in virology (01.08.2015)
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Immunosuppressant therapy averts rejection of allogeneic FKBP1A-disrupted CAR-T cells
Maldini, Colby R., Messana, Angelica C., Bendet, Paula B., Camblin, Adam J., Musenge, Faith M., White, Moriah L., Rocha, Joseph J., Coholan, Lindsey J., Karaca, Cisem, Li, Frederick, Yan, Bo, Vrbanac, Vladimir D., Marte, Emily, Claiborne, Daniel T., Boutwell, Christian L., Allen, Todd M.
Published in Molecular therapy (01.09.2024)
Published in Molecular therapy (01.09.2024)
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Whole genome deep sequencing of HIV-1 reveals the impact of early minor variants upon immune recognition during acute infection
Henn, Matthew R, Boutwell, Christian L, Charlebois, Patrick, Lennon, Niall J, Power, Karen A, Macalalad, Alexander R, Berlin, Aaron M, Malboeuf, Christine M, Ryan, Elizabeth M, Gnerre, Sante, Zody, Michael C, Erlich, Rachel L, Green, Lisa M, Berical, Andrew, Wang, Yaoyu, Casali, Monica, Streeck, Hendrik, Bloom, Allyson K, Dudek, Tim, Tully, Damien, Newman, Ruchi, Axten, Karen L, Gladden, Adrianne D, Battis, Laura, Kemper, Michael, Zeng, Qiandong, Shea, Terrance P, Gujja, Sharvari, Zedlack, Carmen, Gasser, Olivier, Brander, Christian, Hess, Christoph, Günthard, Huldrych F, Brumme, Zabrina L, Brumme, Chanson J, Bazner, Suzane, Rychert, Jenna, Tinsley, Jake P, Mayer, Ken H, Rosenberg, Eric, Pereyra, Florencia, Levin, Joshua Z, Young, Sarah K, Jessen, Heiko, Altfeld, Marcus, Birren, Bruce W, Walker, Bruce D, Allen, Todd M
Published in PLoS pathogens (01.03.2012)
Published in PLoS pathogens (01.03.2012)
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Immunization of BLT Humanized Mice Redirects T Cell Responses to Gag and Reduces Acute HIV-1 Viremia
Claiborne, Daniel T, Dudek, Timothy E, Maldini, Colby R, Power, Karen A, Ghebremichael, Musie, Seung, Edward, Mellors, Elizabeth F, Vrbanac, Vladimir D, Krupp, Katharine, Bisesi, Abigail, Tager, Andrew M, Knipe, David M, Boutwell, Christian L, Allen, Todd M
Published in Journal of virology (15.10.2019)
Published in Journal of virology (15.10.2019)
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Complete viral RNA genome sequencing of ultra-low copy samples by sequence-independent amplification
Malboeuf, Christine M, Yang, Xiao, Charlebois, Patrick, Qu, James, Berlin, Aaron M, Casali, Monica, Pesko, Kendra N, Boutwell, Christian L, DeVincenzo, John P, Ebel, Gregory D, Allen, Todd M, Zody, Michael C, Henn, Matthew R, Levin, Joshua Z
Published in Nucleic acids research (07.01.2013)
Published in Nucleic acids research (07.01.2013)
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Journal Article
Rapid evolution of HIV-1 to functional CD8⁺ T cell responses in humanized BLT mice
Dudek, Timothy E, No, Daniel C, Seung, Edward, Vrbanac, Vladimir D, Fadda, Lena, Bhoumik, Priyasma, Boutwell, Christian L, Power, Karen A, Gladden, Adrianne D, Battis, Laura, Mellors, Elizabeth F, Tivey, Trevor R, Gao, Xiaojiang, Altfeld, Marcus, Luster, Andrew D, Tager, Andrew M, Allen, Todd M
Published in Science translational medicine (18.07.2012)
Published in Science translational medicine (18.07.2012)
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Ultrasensitive detection of minor drug-resistant variants for HIV after nevirapine exposure using allele-specific PCR: clinical significance
Rowley, Christopher F, Boutwell, Christian L, Lee, Esther J, MacLeod, Iain J, Ribaudo, Heather J, Essex, M, Lockman, Shahin
Published in AIDS research and human retroviruses (01.03.2010)
Published in AIDS research and human retroviruses (01.03.2010)
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Improvement in allele-specific PCR assay with the use of polymorphism-specific primers for the analysis of minor variant drug resistance in HIV-1 subtype C
Rowley, Christopher F., Boutwell, Christian L., Lockman, Shahin, Essex, M.
Published in Journal of virological methods (01.04.2008)
Published in Journal of virological methods (01.04.2008)
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Journal Article
The Detection of Acute HIV Infection
Boutwell, Christian L., Rolland, Morgane M., Herbeck, Joshua T., Mullins, James I., Allen, Todd M.
Published in The Journal of infectious diseases (01.10.2010)
Published in The Journal of infectious diseases (01.10.2010)
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