Selective RET kinase inhibition for patients with RET-altered cancers
Subbiah, V., Velcheti, V., Tuch, B.B., Ebata, K., Busaidy, N.L., Cabanillas, M.E., Wirth, L.J., Stock, S., Smith, S., Lauriault, V., Corsi-Travali, S., Henry, D., Burkard, M., Hamor, R., Bouhana, K., Winski, S., Wallace, R.D., Hartley, D., Rhodes, S., Reddy, M., Brandhuber, B.J., Andrews, S., Rothenberg, S.M., Drilon, A.
Published in Annals of oncology (01.08.2018)
Published in Annals of oncology (01.08.2018)
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Suppression of ocular neovascularization with siRNA targeting VEGF receptor 1
SHEN, J, SAMUL, R, VARGEESE, C, GOMEZ, A, BOUHANA, K, AITCHISON, R, PAVCO, P, CAMPOCHIARO, P. A, SILVA, R. L, AKIYAMA, H, LIU, H, SAISHIN, Y, HACKETT, S. F, ZINNEN, S, KOSSEN, K, FOSNAUGH, K
Published in Gene therapy (01.02.2006)
Published in Gene therapy (01.02.2006)
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391 LOXO-101, a pan TRK inhibitor, for the treatment of TRK-driven cancers
Winski, S, Baer, B, Hartley, D, Rhodes, S, Wallace, R, Smith, S, Nanda, N, Kunkle, L, Lee, P, Bouhana, K
Published in European journal of cancer (1990) (01.11.2014)
Published in European journal of cancer (1990) (01.11.2014)
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The development of a potent, KDR/VEGFR2-sparing RET kinase inhibitor for treating patients with RET-dependent cancers
Brandhuber, B, Haas, J, Tuch, B, Ebata, K, Bouhana, K, McFaddin, E, Williams, L, Winski, S, Brown, E, Burkhard, M, Nanda, N, Hamor, R, Sullivan, F, Hanson, L, Morales, T, Vigers, G, Wallace, R.D, Blake, J, Andrews, S, Rothenberg, S.M
Published in European journal of cancer (1990) (01.12.2016)
Published in European journal of cancer (1990) (01.12.2016)
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The development of LOXO-195, a second generation TRK kinase inhibitor that overcomes acquired resistance to 1st generation inhibitors observed in patients with TRK-fusion cancers
Blake, J, Kolakowski, G.R, Tuch, B, Ebata, K, Brandhuber, B, Winski, S, Bouhana, K, Nanda, N, Wu, W.I, Parker, A, Hamor, R, Larsen, P.D, Sullivan, F, DeWolf, W, Neitzel, N, Wollenberg, L, Andrews, S, Rothenberg, S.M
Published in European journal of cancer (1990) (01.12.2016)
Published in European journal of cancer (1990) (01.12.2016)
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Pharmacokinetics and Tissue Distribution of a Ribozyme Directed Against Hepatitis C Virus RNA Following Subcutaneous or Intravenous Administration in Mice
Lee, Patrice A., Blatt, Lawrence M., Blanchard, Karin S., Bouhana, Karyn S., Pavco, Pamela A., Bellon, Laurent, Sandberg, Jennifer A.
Published in Hepatology (Baltimore, Md.) (01.09.2000)
Published in Hepatology (Baltimore, Md.) (01.09.2000)
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Antitumor and Antimetastatic Activity of Ribozymes Targeting the Messenger RNA of Vascular Endothelial Growth Factor Receptors
Pavco, P A, Bouhana, K S, Gallegos, A M, Agrawal, A, Blanchard, K S, Grimm, S L, Jensen, K L, Andrews, L E, Wincott, F E, Pitot, P A, Tressler, R J, Cushman, C, Reynolds, M A, Parry, T J
Published in Clinical cancer research (01.05.2000)
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Published in Clinical cancer research (01.05.2000)
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162 MEK162 (ARRY-162), a novel MEK 1/2 inhibitor, inhibits tumor growth regardless of KRas/Raf pathway mutations
Winski, S, Anderson, D, Bouhana, K, Impastato, R, Woessner, R, Zuzack, J, Tunquist, B, Garrus, J, Pheneger, T, Lee, P
Published in European journal of cancer supplements (2010)
Published in European journal of cancer supplements (2010)
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In Vivo Pre-clinical characterization of a Novel Series of FGFR2 Selective Inhibitors with Potency Against Clinically Relevant Mutations
Fischer, J., Bouhana, K., Chicarelli, M.J., Dahlke, J., Fell, B., Fulton, J., Guarnieri, A., Haygood, L., Jalluri, R., Johnson, A., McLean, B., Max, M., Rieger, R., Robinson, J., Rodriguez, M., Sullivan, F., Wang, Y., Winski, S., Zhou, Y.
Published in European journal of cancer (1990) (01.10.2022)
Published in European journal of cancer (1990) (01.10.2022)
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Pre-clinical In Vitro and In Vivo Characterization of a Novel EGFR Sparing ErbB2 Inhibitor with Activity Against Oncogenic ErbB2 Mutations
Chicarelli, M.J., Bouhana, K., Cable, L., Crow, M., Fell, B., Fischer, J., Fulton, J., Guarnieri, A., Jalluri, R., Robinson, J., Sullivan, F., Winski, S., Zhou, Y.
Published in European journal of cancer (1990) (01.10.2022)
Published in European journal of cancer (1990) (01.10.2022)
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Ribozyme pharmacokinetic screening for predicting pharmacodynamic dosing regimens
Parry, T J, Bouhana, K S, Blanchard, K S, Pavco, P A, Sandberg, J A
Published in Current Issues in Molecular Biology (01.10.2000)
Published in Current Issues in Molecular Biology (01.10.2000)
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442 - The development of LOXO-195, a second generation TRK kinase inhibitor that overcomes acquired resistance to 1st generation inhibitors observed in patients with TRK-fusion cancers
Blake, J., Kolakowski, G.R., Tuch, B., Ebata, K., Brandhuber, B., Winski, S., Bouhana, K., Nanda, N., Wu, W.I., Parker, A., Hamor, R., Larsen, P.D., Sullivan, F., DeWolf, W., Neitzel, N., Wollenberg, L., Andrews, S., Rothenberg, S.M.
Published in European journal of cancer (1990) (01.12.2016)
Published in European journal of cancer (1990) (01.12.2016)
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Journal Article
441 - The development of a potent, KDR/VEGFR2-sparing RET kinase inhibitor for treating patients with RET-dependent cancers
Brandhuber, B., Haas, J., Tuch, B., Ebata, K., Bouhana, K., McFaddin, E., Williams, L., Winski, S., Brown, E., Burkhard, M., Nanda, N., Hamor, R., Sullivan, F., Hanson, L., Morales, T., Vigers, G., Wallace, R.D., Blake, J., Andrews, S., Rothenberg, S.M.
Published in European journal of cancer (1990) (01.12.2016)
Published in European journal of cancer (1990) (01.12.2016)
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Journal Article
Ribozymes as Tools for Therapeutic Target Validation in Arthritis
Jarvis, Thale C, Bouhana, Karyn S, Lesch, Mark E, Brown, Suzy A, Parry, Tom J, Schrier, Denis J, Hunt, Stephen W., III, Pavco, Pamela A, Flory, Craig M
Published in The Journal of immunology (1950) (01.07.2000)
Published in The Journal of immunology (1950) (01.07.2000)
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In Vivo Activity of ARRY-380, a Potent, Small Molecule Inhibitor of ErbB2 in Combination with Trastuzumab, Docetaxel or Bevacizumab
Lee, P., Anderson, D., Bouhana, K., Garrus, J., Napier, C., Avrustkaya, A., White, A., Pheneger, T., Winkler, J.
Published in Cancer research (Chicago, Ill.) (15.12.2009)
Published in Cancer research (Chicago, Ill.) (15.12.2009)
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Sustained blockade of neurotrophin receptors TrkA, TrkB and TrkC reduces non-malignant skeletal pain but not the maintenance of sensory and sympathetic nerve fibers
Ghilardi, Joseph R, Freeman, Katie T, Jimenez-Andrade, Juan M, Mantyh, William G, Bloom, Aaron P, Bouhana, Karyn S, Trollinger, David, Winkler, James, Lee, Patrice, Andrews, Steven W, Kuskowski, Michael A, Mantyh, Patrick W
Published in Bone (New York, N.Y.) (01.02.2011)
Published in Bone (New York, N.Y.) (01.02.2011)
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Expression of metalloproteinases and metalloproteinase inhibitors by fetal astrocytes and glioma cells
Apodaca, G, Rutka, J T, Bouhana, K, Berens, M E, Giblin, J R, Rosenblum, M L, McKerrow, J H, Banda, M J
Published in Cancer research (Chicago, Ill.) (15.04.1990)
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Published in Cancer research (Chicago, Ill.) (15.04.1990)
Journal Article
Pharmacokinetics of an antiangiogenic ribozyme (ANGIOZYME) in the mouse
Sandberg, J A, Bouhana, K S, Gallegos, A M, Agrawal, A B, Grimm, S L, Wincott, F E, Reynolds, M A, Pavco, P A, Parry, T J
Published in Antisense & nucleic acid drug development (01.06.1999)
Published in Antisense & nucleic acid drug development (01.06.1999)
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