Response to mTOR and PI3K inhibitors in enzalutamide-resistant luminal androgen receptor triple-negative breast cancer patient-derived xenografts
Coussy, Florence, Lavigne, Marion, de Koning, Leanne, Botty, Rania El, Nemati, Fariba, Naguez, Adnan, Bataillon, Guillaume, Ouine, Berengère, Dahmani, Ahmed, Montaudon, Elodie, Painsec, Pierre, Chateau-Joubert, Sophie, Laetitia, Fuhrmann, Larcher, Thibaut, Vacher, Sophie, Chemlali, Walid, Briaux, Adrien, Melaabi, Samia, Salomon, Anne Vincent, Guinebretiere, Jean Marc, Bieche, Ivan, Marangoni, Elisabetta
Published in Theranostics (2020)
Published in Theranostics (2020)
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HORMAD1 overexpression predicts response to anthracycline-cyclophosphamide and survival in triple-negative breast cancers
El-Botty, Rania, Vacher, Sophie, Mainguené, Juliette, Briaux, Adrien, Ibadioune, Sabrina, Dahmani, Ahmed, Montaudon, Elodie, Nemati, Fariba, Huguet, Léa, Sourd, Laura, Morriset, Ludivine, Château-Joubert, Sophie, Dubois, Thierry, Maire, Virginie, Lidereau, Rosette, Rapinat, Audrey, Gentien, David, Coussy, Florence, Bièche, Ivan, Marangoni, Elisabetta
Published in Molecular oncology (01.10.2023)
Published in Molecular oncology (01.10.2023)
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Targeting mTOR pathway inhibits tumor growth in different molecular subtypes of triple-negative breast cancers
Hatem, Rana, El Botty, Rania, Chateau-Joubert, Sophie, Servely, Jean-Luc, Labiod, Dalila, de Plater, Ludmilla, Assayag, Franck, Coussy, Florence, Callens, Céline, Vacher, Sophie, Reyal, Fabien, Cosulich, Sabina, Diéras, Véronique, Bièche, Ivan, Marangoni, Elisabetta
Published in Oncotarget (26.07.2016)
Published in Oncotarget (26.07.2016)
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PLK1 inhibition exhibits strong anti-tumoral activity in CCND1-driven breast cancer metastases with acquired palbociclib resistance
Montaudon, Elodie, Nikitorowicz-Buniak, Joanna, Sourd, Laura, Morisset, Ludivine, El Botty, Rania, Huguet, Léa, Dahmani, Ahmed, Painsec, Pierre, Nemati, Fariba, Vacher, Sophie, Chemlali, Walid, Masliah-Planchon, Julien, Château-Joubert, Sophie, Rega, Camilla, Leal, Mariana Ferreira, Simigdala, Nikiana, Pancholi, Sunil, Ribas, Ricardo, Nicolas, André, Meseure, Didier, Vincent-Salomon, Anne, Reyes, Cécile, Rapinat, Audrey, Gentien, David, Larcher, Thibaut, Bohec, Mylène, Baulande, Sylvain, Bernard, Virginie, Decaudin, Didier, Coussy, Florence, Le Romancer, Muriel, Dutertre, Guillaume, Tariq, Zakia, Cottu, Paul, Driouch, Keltouma, Bièche, Ivan, Martin, Lesley-Ann, Marangoni, Elisabetta
Published in Nature communications (13.08.2020)
Published in Nature communications (13.08.2020)
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Oxidative phosphorylation is a metabolic vulnerability of endocrine therapy and palbociclib resistant metastatic breast cancers
El-Botty, Rania, Morriset, Ludivine, Montaudon, Elodie, Tariq, Zakia, Schnitzler, Anne, Bacci, Marina, Lorito, Nicla, Sourd, Laura, Huguet, Léa, Dahmani, Ahmed, Painsec, Pierre, Derrien, Heloise, Vacher, Sophie, Masliah-Planchon, Julien, Raynal, Virginie, Baulande, Sylvain, Larcher, Thibaut, Vincent-Salomon, Anne, Dutertre, Guillaume, Cottu, Paul, Gentric, Géraldine, Mechta-Grigoriou, Fatima, Hutton, Scott, Driouch, Keltouma, Bièche, Ivan, Morandi, Andrea, Marangoni, Elisabetta
Published in Nature communications (14.07.2023)
Published in Nature communications (14.07.2023)
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Homologous recombination deficiency derived from whole-genome sequencing predicts platinum response in triple-negative breast cancers
ter Brugge, Petra, Moser, Sarah C., Bièche, Ivan, Kristel, Petra, Ibadioune, Sabrina, Eeckhoutte, Alexandre, de Bruijn, Roebi, van der Burg, Eline, Lutz, Catrin, Annunziato, Stefano, de Ruiter, Julian, Masliah Planchon, Julien, Vacher, Sophie, Courtois, Laura, El-Botty, Rania, Dahmani, Ahmed, Montaudon, Elodie, Morisset, Ludivine, Sourd, Laura, Huguet, Léa, Derrien, Heloise, Nemati, Fariba, Chateau-Joubert, Sophie, Larcher, Thibaut, Salomon, Anne, Decaudin, Didier, Reyal, Fabien, Coussy, Florence, Popova, Tatiana, Wesseling, Jelle, Stern, Marc-Henri, Jonkers, Jos, Marangoni, Elisabetta
Published in Nature communications (07.04.2023)
Published in Nature communications (07.04.2023)
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Interaction between IGF2‐PI3K axis and cancer‐associated‐fibroblasts promotes anal squamous carcinogenesis
Cacheux, Wulfran, Lièvre, Astrid, Richon, Sophie, Vacher, Sophie, El Alam, Elsy, Briaux, Adrien, El Botty, Rania, Mariani, Pascale, Buecher, Bruno, Schnitzler, Anne, Barbazan, Jorge, Roman‐Roman, Sergio, Bièche, Ivan, Dangles‐Marie, Virginie
Published in International journal of cancer (01.10.2019)
Published in International journal of cancer (01.10.2019)
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A large collection of integrated genomically characterized patient‐derived xenografts highlighting the heterogeneity of triple‐negative breast cancer
Coussy, Florence, Koning, Leanne, Lavigne, Marion, Bernard, Virginie, Ouine, Berengere, Boulai, Anais, El Botty, Rania, Dahmani, Ahmed, Montaudon, Elodie, Assayag, Franck, Morisset, Ludivine, Huguet, Lea, Sourd, Laura, Painsec, Pierre, Callens, Celine, Chateau‐Joubert, Sophie, Servely, Jean‐Luc, Larcher, Thibaut, Reyes, Cecile, Girard, Elodie, Pierron, Gaelle, Laurent, Cecile, Vacher, Sophie, Baulande, Sylvain, Melaabi, Samia, Vincent‐Salomon, Anne, Gentien, David, Dieras, Veronique, Bieche, Ivan, Marangoni, Elisabetta
Published in International journal of cancer (01.10.2019)
Published in International journal of cancer (01.10.2019)
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Analysis of genomic and non-genomic signaling of estrogen receptor in PDX models of breast cancer treated with a combination of the PI3K inhibitor alpelisib (BYL719) and fulvestrant
Jacquemetton, Julien, Kassem, Loay, Poulard, Coralie, Dahmani, Ahmed, De Plater, Ludmilla, Montaudon, Elodie, Sourd, Laura, Morisset, Ludivine, El Botty, Rania, Chateau-Joubert, Sophie, Vacher, Sophie, Bièche, Ivan, Treilleux, Isabelle, Trédan, Olivier, Marangoni, Elisabetta, Le Romancer, Muriel
Published in Breast cancer research : BCR (21.05.2021)
Published in Breast cancer research : BCR (21.05.2021)
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Journal Article
PARP Inhibition Increases the Response to Chemotherapy in Uveal Melanoma
de Koning, Leanne, Decaudin, Didier, El Botty, Rania, Nicolas, André, Carita, Guillaume, Schuller, Mathieu, Ouine, Bérengère, Cartier, Aurélie, Naguez, Adnan, Fleury, Justine, Cooke, Vesselina, Wylie, Andrew, Smith, Paul, Marangoni, Elisabetta, Gentien, David, Meseure, Didier, Mariani, Pascale, Cassoux, Nathalie, Piperno-Neumann, Sophie, Roman-Roman, Sergio, Némati, Fariba
Published in Cancers (29.05.2019)
Published in Cancers (29.05.2019)
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Dramatic In Vivo Efficacy of the EZH2-Inhibitor Tazemetostat in PBRM1 -Mutated Human Chordoma Xenograft
Passeri, Thibault, Dahmani, Ahmed, Masliah-Planchon, Julien, Naguez, Adnan, Michou, Marine, El Botty, Rania, Vacher, Sophie, Bouarich, Rachida, Nicolas, André, Polivka, Marc, Franck, Coralie, Schnitzler, Anne, Némati, Fariba, Roman-Roman, Sergio, Bourdeaut, Franck, Adle-Biassette, Homa, Mammar, Hamid, Froelich, Sébastien, Bièche, Ivan, Decaudin, Didier
Published in Cancers (14.03.2022)
Published in Cancers (14.03.2022)
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In vivo efficacy assessment of the CDK4/6 inhibitor palbociclib and the PLK1 inhibitor volasertib in human chordoma xenografts
Passeri, Thibault, Dahmani, Ahmed, Masliah-Planchon, Julien, El Botty, Rania, Courtois, Laura, Vacher, Sophie, Marangoni, Elisabetta, Nemati, Fariba, Roman-Roman, Sergio, Adle-Biassette, Homa, Mammar, Hamid, Froelich, Sébastien, Bièche, Ivan, Decaudin, Didier
Published in Frontiers in oncology (25.11.2022)
Published in Frontiers in oncology (25.11.2022)
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HRAS is a therapeutic target in malignant chemo-resistant adenomyoepithelioma of the breast
Bièche, Ivan, Coussy, Florence, El-Botty, Rania, Vacher, Sophie, Château-Joubert, Sophie, Dahmani, Ahmed, Montaudon, Elodie, Reyes, Cécile, Gentien, David, Reyal, Fabien, Ricci, Francesco, Nicolas, André, Marchio, Caterina, Vincent-Salomon, Anne, Laé, Marick, Marangoni, Elisabetta
Published in Journal of hematology and oncology (08.09.2021)
Published in Journal of hematology and oncology (08.09.2021)
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Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts
Woo, Xing Yi, Giordano, Jessica, Srivastava, Anuj, Zhao, Zi-Ming, Lloyd, Michael W., de Bruijn, Roebi, Suh, Yun-Suhk, Patidar, Rajesh, Chen, Li, Scherer, Sandra, Bailey, Matthew H., Yang, Chieh-Hsiang, Cortes-Sanchez, Emilio, Xi, Yuanxin, Wang, Jing, Wickramasinghe, Jayamanna, Kossenkov, Andrew V., Rebecca, Vito W., Sun, Hua, Mashl, R. Jay, Davies, Sherri R., Jeon, Ryan, Frech, Christian, Randjelovic, Jelena, Rosains, Jacqueline, Galimi, Francesco, Bertotti, Andrea, Lafferty, Adam, O’Farrell, Alice C., Modave, Elodie, Lambrechts, Diether, ter Brugge, Petra, Serra, Violeta, Marangoni, Elisabetta, El Botty, Rania, Kim, Hyunsoo, Kim, Jong-Il, Yang, Han-Kwang, Lee, Charles, Dean, Dennis A., Davis-Dusenbery, Brandi, Evrard, Yvonne A., Doroshow, James H., Welm, Alana L., Welm, Bryan E., Lewis, Michael T., Fang, Bingliang, Roth, Jack A., Meric-Bernstam, Funda, Herlyn, Meenhard, Davies, Michael A., Ding, Li, Li, Shunqiang, Govindan, Ramaswamy, Isella, Claudio, Moscow, Jeffrey A., Trusolino, Livio, Byrne, Annette T., Jonkers, Jos, Bult, Carol J., Medico, Enzo, Chuang, Jeffrey H.
Published in Nature genetics (01.01.2021)
Published in Nature genetics (01.01.2021)
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Targeting Transcriptional Regulation with a CDK9 Inhibitor Suppresses Growth of Endocrine- and Palbociclib-Resistant ER+ Breast Cancers
Soosainathan, Arany, Iravani, Marjan, El-Botty, Rania, Alexander, John, Sourd, Laura, Morisset, Ludivine, Painsec, Pierre, Orha, Rebecca, Nikitorowicz-Buniak, Joanna, Pancholi, Sunil, Haider, Syed, Dowsett, Mitch, Marangoni, Elisabetta, Martin, Lesley-Ann, Isacke, Clare M
Published in Cancer research (Chicago, Ill.) (02.01.2024)
Published in Cancer research (Chicago, Ill.) (02.01.2024)
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BRCAness, SLFN11, and RB1 loss predict response to topoisomerase I inhibitors in triple-negative breast cancers
Coussy, Florence, El-Botty, Rania, Château-Joubert, Sophie, Dahmani, Ahmed, Montaudon, Elodie, Leboucher, Sophie, Morisset, Ludivine, Painsec, Pierre, Sourd, Laura, Huguet, Léa, Nemati, Fariba, Servely, Jean-Luc, Larcher, Thibaut, Vacher, Sophie, Briaux, Adrien, Reyes, Cécile, La Rosa, Philippe, Lucotte, Georges, Popova, Tatiana, Foidart, Pierre, Sounni, Nor Eddine, Noel, Agnès, Decaudin, Didier, Fuhrmann, Laetitia, Salomon, Anne, Reyal, Fabien, Mueller, Christopher, Ter Brugge, Petra, Jonkers, Jos, Poupon, Marie-France, Stern, Marc-Henri, Bièche, Ivan, Pommier, Yves, Marangoni, Elisabetta
Published in Science translational medicine (19.02.2020)
Published in Science translational medicine (19.02.2020)
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In vitro bone metastasis dwelling in a 3D bioengineered niche
Han, Weijing, El Botty, Rania, Montaudon, Elodie, Malaquin, Laurent, Deschaseaux, Frederic, Espagnolle, Nicolas, Marangoni, Elisabetta, Cottu, Paul, Zalcman, Gérard, Parrini, Maria Carla, Assayag, Franck, Sensebe, Luc, Silberzan, Pascal, Vincent-Salomon, Anne, Dutertre, Guillaume, Roman-Roman, Sergio, Descroix, Stephanie, Camonis, Jacques
Published in Biomaterials (01.02.2021)
Published in Biomaterials (01.02.2021)
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Acetyl-CoA carboxylase 1 controls a lipid droplet-peroxisome axis and is a vulnerability of endocrine-resistant ER + breast cancer
Bacci, Marina, Lorito, Nicla, Smiriglia, Alfredo, Subbiani, Angela, Bonechi, Francesca, Comito, Giuseppina, Morriset, Ludivine, El Botty, Rania, Benelli, Matteo, López-Velazco, Joanna I, Caffarel, Maria M, Urruticoechea, Ander, Sflomos, George, Malorni, Luca, Corsini, Michela, Ippolito, Luigi, Giannoni, Elisa, Meattini, Icro, Matafora, Vittoria, Havas, Kristina, Bachi, Angela, Chiarugi, Paola, Marangoni, Elisabetta, Morandi, Andrea
Published in Science translational medicine (28.02.2024)
Published in Science translational medicine (28.02.2024)
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Capecitabine Efficacy Is Correlated with TYMP and RB1 Expression in PDX Established from Triple-Negative Breast Cancers
Marangoni, Elisabetta, Laurent, Cécile, Coussy, Florence, El-Botty, Rania, Château-Joubert, Sophie, Servely, Jean-Luc, de Plater, Ludmilla, Assayag, Franck, Dahmani, Ahmed, Montaudon, Elodie, Nemati, Fariba, Fleury, Justine, Vacher, Sophie, Gentien, David, Rapinat, Audrey, Foidart, Pierre, Sounni, Nor Eddine, Noel, Agnès, Vincent-Salomon, Anne, Lae, Marick, Decaudin, Didier, Roman-Roman, Sergio, Bièche, Ivan, Piccart, Martine, Reyal, Fabien
Published in Clinical cancer research (01.06.2018)
Published in Clinical cancer research (01.06.2018)
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Abstract 3859: Efficacy of capecitabine in chemoresistant PDX established from triple-negative breast cancers with residual disease after neoadjuvant chemotherapy
Marangoni, Elisabetta, Laurent, Cécile, Coussy, Florence, Botty, Rania El, Plater, Ludmilla de, Assayag, Franck, Vacher, Sophie, Bièche, Ivan, Reyal, Fabien
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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