The Role of the Immune System in Cutaneous Squamous Cell Carcinoma
Bottomley, Matthew J, Thomson, Jason, Harwood, Catherine, Leigh, Irene
Published in International journal of molecular sciences (24.04.2019)
Published in International journal of molecular sciences (24.04.2019)
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Journal Article
Molecular Insights into Quorum Sensing in the Human Pathogen Pseudomonas aeruginosa from the Structure of the Virulence Regulator LasR Bound to Its Autoinducer
Bottomley, Matthew J., Muraglia, Ester, Bazzo, Renzo, Carfì, Andrea
Published in The Journal of biological chemistry (04.05.2007)
Published in The Journal of biological chemistry (04.05.2007)
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Journal Article
Cutaneous adaptive immunity and uraemia: a narrative review
Zibandeh, Noushin, Li, Zehua, Ogg, Graham, Bottomley, Matthew J
Published in Frontiers in immunology (27.09.2024)
Published in Frontiers in immunology (27.09.2024)
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Journal Article
Protein Crystallography in Vaccine Research and Development
Malito, Enrico, Carfi, Andrea, Bottomley, Matthew J
Published in International Journal of Molecular Sciences (09.06.2015)
Published in International Journal of Molecular Sciences (09.06.2015)
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Journal Article
Book Review
Mechanistic implications for LDL receptor degradation from the PCSK9/LDLR structure at neutral pH
Surdo, Paola Lo, Bottomley, Matthew J, Calzetta, Alessandra, Settembre, Ethan C, Cirillo, Agostino, Pandit, Shilpa, Ni, Yan G, Hubbard, Brian, Sitlani, Ayesha, Carfí, Andrea
Published in EMBO reports (01.12.2011)
Published in EMBO reports (01.12.2011)
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Journal Article
Structural and Functional Analysis of the Human HDAC4 Catalytic Domain Reveals a Regulatory Structural Zinc-binding Domain
Bottomley, Matthew J., Lo Surdo, Paola, Di Giovine, Paolo, Cirillo, Agostino, Scarpelli, Rita, Ferrigno, Federica, Jones, Philip, Neddermann, Petra, De Francesco, Raffaele, Steinkühler, Christian, Gallinari, Paola, Carfí, Andrea
Published in The Journal of biological chemistry (26.09.2008)
Published in The Journal of biological chemistry (26.09.2008)
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Journal Article
Molecular Basis of Ligand-Dependent Regulation of NadR, the Transcriptional Repressor of Meningococcal Virulence Factor NadA
Liguori, Alessia, Malito, Enrico, Lo Surdo, Paola, Fagnocchi, Luca, Cantini, Francesca, Haag, Andreas F, Brier, Sébastien, Pizza, Mariagrazia, Delany, Isabel, Bottomley, Matthew J
Published in PLoS pathogens (01.04.2016)
Published in PLoS pathogens (01.04.2016)
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Journal Article
Dampened Inflammatory Signalling and Myeloid-Derived Suppressor-Like Cell Accumulation Reduces Circulating Monocytic HLA-DR Density and May Associate With Malignancy Risk in Long-Term Renal Transplant Recipients
Bottomley, Matthew J., Harden, Paul N., Wood, Kathryn J., Hester, Joanna, Issa, Fadi
Published in Frontiers in immunology (01.07.2022)
Published in Frontiers in immunology (01.07.2022)
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Journal Article
Defining a protective epitope on factor H binding protein, a key meningococcal virulence factor and vaccine antigen
Malito, Enrico, Faleri, Agnese, Surdo, Paola Lo, Veggi, Daniele, Maruggi, Giulietta, Grassi, Eva, Cartocci, Elena, Bertoldi, Isabella, Genovese, Alessia, Santini, Laura, Romagnoli, Giacomo, Borgogni, Erica, Brier, Sébastien, Passo, Carla Lo, Domina, Maria, Castellino, Flora, Felici, Franco, van der Veen, Stijn, Johnson, Steven, Lea, Susan M., Tang, Christoph M., Pizza, Mariagrazia, Savino, Silvana, Norais, Nathalie, Rappuoli, Rino, Bottomley, Matthew J., Masignani, Vega
Published in Proceedings of the National Academy of Sciences - PNAS (26.02.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (26.02.2013)
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Journal Article
The respiratory syncytial virus (RSV) prefusion F‐protein functional antibody repertoire in adult healthy donors
Andreano, Emanuele, Paciello, Ida, Bardelli, Monia, Tavarini, Simona, Sammicheli, Chiara, Frigimelica, Elisabetta, Guidotti, Silvia, Torricelli, Giulia, Biancucci, Marco, D’Oro, Ugo, Chandramouli, Sumana, Bottomley, Matthew J, Rappuoli, Rino, Finco, Oretta, Buricchi, Francesca
Published in EMBO molecular medicine (07.06.2021)
Published in EMBO molecular medicine (07.06.2021)
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Journal Article
The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression
Org, Tõnis, Chignola, Francesca, Hetényi, Csaba, Gaetani, Massimiliano, Rebane, Ana, Liiv, Ingrid, Maran, Uko, Mollica, Luca, Bottomley, Matthew J, Musco, Giovanna, Peterson, Pärt
Published in EMBO reports (01.04.2008)
Published in EMBO reports (01.04.2008)
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Journal Article
Crystal structure reveals vaccine elicited bactericidal human antibody targeting a conserved epitope on meningococcal fHbp
López-Sagaseta, Jacinto, Beernink, Peter T., Bianchi, Federica, Santini, Laura, Frigimelica, Elisabetta, Lucas, Alexander H., Pizza, Mariagrazia, Bottomley, Matthew J.
Published in Nature communications (06.02.2018)
Published in Nature communications (06.02.2018)
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Journal Article
4CMenB vaccine induces elite cross-protective human antibodies that compete with human factor H for binding to meningococcal fHbp
Veggi, Daniele, Bianchi, Federica, Santini, Laura, Lo Surdo, Paola, Chesterman, Chelsy C, Pansegrau, Werner, Bechi, Nicoletta, Huang, Ying, Masignani, Vega, Pizza, Mariagrazia, Rappuoli, Rino, Bottomley, Matthew J, Cozzi, Roberta, Maione, Domenico
Published in PLoS pathogens (02.10.2020)
Published in PLoS pathogens (02.10.2020)
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Journal Article
Self-assembling protein nanoparticles in the design of vaccines
López-Sagaseta, Jacinto, Malito, Enrico, Rappuoli, Rino, Bottomley, Matthew J.
Published in Computational and structural biotechnology journal (01.01.2016)
Published in Computational and structural biotechnology journal (01.01.2016)
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Journal Article
Apo, Zn2+-bound and Mn2+-bound structures reveal ligand-binding properties of SitA from the pathogen Staphylococcus pseudintermedius
Abate, Francesca, Malito, Enrico, Cozzi, Roberta, Lo Surdo, Paola, Maione, Domenico, Bottomley, Matthew J
Published in Bioscience reports (24.11.2014)
Published in Bioscience reports (24.11.2014)
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Journal Article
Research engagement by British early-career practitioners in nephrology: a multidisciplinary survey
Bottomley, Matthew J, Beckwith, Hannah, McMahon, Aisling, Nation, Michael, Wheeler, David C, Greenwood, Sharlene, Hughes, Jeremy, Sheerin, Neil S
Published in BMJ open (14.12.2022)
Published in BMJ open (14.12.2022)
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Journal Article
Structures of NHBA elucidate a broadly conserved epitope identified by a vaccine induced antibody
Maritan, Martina, Veggi, Daniele, Cozzi, Roberta, Dello Iacono, Lucia, Bartolini, Erika, Lo Surdo, Paola, Maruggi, Giulietta, Spraggon, Glen, Bottomley, Matthew J, Malito, Enrico
Published in PloS one (22.08.2018)
Published in PloS one (22.08.2018)
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Journal Article
NadA3 Structures Reveal Undecad Coiled Coils and LOX1 Binding Regions Competed by Meningococcus B Vaccine-Elicited Human Antibodies
Liguori, Alessia, Dello Iacono, Lucia, Maruggi, Giulietta, Benucci, Barbara, Merola, Marcello, Lo Surdo, Paola, López-Sagaseta, Jacinto, Pizza, Mariagrazia, Malito, Enrico, Bottomley, Matthew J
Published in mBio (16.10.2018)
Published in mBio (16.10.2018)
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Journal Article
Bactericidal human monoclonal antibody 1B1 shows specificity for meningococcal factor H binding protein variant 2 and displaces human factor H
Veggi, Daniele, Chesterman, Chelsy C., Santini, Laura, Huang, Ying, Pacchiani, Nicola, Sierra, Jeannette, Chen, Lynn, Laliberte, Jason, Bianchi, Federica, Cozzi, Roberta, Frigimelica, Elisabetta, Maione, Domenico, Finco, Oretta, Bottomley, Matthew J.
Published in FASEB bioAdvances (01.08.2024)
Published in FASEB bioAdvances (01.08.2024)
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Journal Article