Targeting Tyrosine Phosphatases: Time to End the Stigma
Stanford, Stephanie M, Bottini, Nunzio
Published in Trends in pharmacological sciences (Regular ed.) (01.06.2017)
Published in Trends in pharmacological sciences (Regular ed.) (01.06.2017)
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Journal Article
The Contribution of PTPN22 to Rheumatic Disease
Mustelin, Tomas, Bottini, Nunzio, Stanford, Stephanie M.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.04.2019)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.04.2019)
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Journal Article
Secreted Protein Acidic and Rich in Cysteine Mediated Biomimetic Delivery of Methotrexate by Albumin-Based Nanomedicines for Rheumatoid Arthritis Therapy
Liu, Lu, Hu, Fanlei, Wang, Hui, Wu, Xiaoli, Eltahan, Ahmed Shaker, Stanford, Stephanie, Bottini, Nunzio, Xiao, Haihua, Bottini, Massimo, Guo, Weisheng, Liang, Xing-Jie
Published in ACS nano (28.05.2019)
Published in ACS nano (28.05.2019)
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Surface Polyethylene Glycol Conformation Influences the Protein Corona of Polyethylene Glycol-Modified Single-Walled Carbon Nanotubes: Potential Implications on Biological Performance
Sacchetti, Cristiano, Motamedchaboki, Khatereh, Magrini, Andrea, Palmieri, Graziana, Mattei, Maurizio, Bernardini, Sergio, Rosato, Nicola, Bottini, Nunzio, Bottini, Massimo
Published in ACS nano (26.03.2013)
Published in ACS nano (26.03.2013)
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Journal Article
Altered thymic differentiation and modulation of arthritis by invariant NKT cells expressing mutant ZAP70
Zhao, Meng, Svensson, Mattias N. D., Venken, Koen, Chawla, Ashu, Liang, Shu, Engel, Isaac, Mydel, Piotr, Day, Jeremy, Elewaut, Dirk, Bottini, Nunzio, Kronenberg, Mitchell
Published in Nature communications (06.07.2018)
Published in Nature communications (06.07.2018)
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Journal Article
Role of PTPN22 in type 1 diabetes and other autoimmune diseases
Bottini, Nunzio, Vang, Torkel, Cucca, Francesco, Mustelin, Tomas
Published in Seminars in Immunology (01.08.2006)
Published in Seminars in Immunology (01.08.2006)
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Journal Article
The Autoimmunity-Associated Gene PTPN22 Potentiates Toll-like Receptor-Driven, Type 1 Interferon-Dependent Immunity
Wang, Yaya, Shaked, Iftach, Stanford, Stephanie M., Zhou, Wenbo, Curtsinger, Julie M., Mikulski, Zbigniew, Shaheen, Zachary R., Cheng, Genhong, Sawatzke, Kristy, Campbell, Amanda M., Auger, Jennifer L., Bilgic, Hatice, Shoyama, Fernanda M., Schmeling, David O., Balfour, Henry H., Hasegawa, Kiminori, Chan, Andrew C., Corbett, John A., Binstadt, Bryce A., Mescher, Matthew F., Ley, Klaus, Bottini, Nunzio, Peterson, Erik J.
Published in Immunity (Cambridge, Mass.) (25.07.2013)
Published in Immunity (Cambridge, Mass.) (25.07.2013)
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Journal Article
Reduced expression of phosphatase PTPN2 promotes pathogenic conversion of Tregs in autoimmunity
Svensson, Mattias Nd, Doody, Karen M, Schmiedel, Benjamin J, Bhattacharyya, Sourya, Panwar, Bharat, Wiede, Florian, Yang, Shen, Santelli, Eugenio, Wu, Dennis J, Sacchetti, Cristiano, Gujar, Ravindra, Seumois, Gregory, Kiosses, William B, Aubry, Isabelle, Kim, Gisen, Mydel, Piotr, Sakaguchi, Shimon, Kronenberg, Mitchell, Tiganis, Tony, Tremblay, Michel L, Ay, Ferhat, Vijayanand, Pandurangan, Bottini, Nunzio
Published in The Journal of clinical investigation (01.03.2019)
Published in The Journal of clinical investigation (01.03.2019)
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Journal Article
Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant
Mustelin, Tomas, Musumeci, Lucia, Tautz, Lutz, Taskén, Kjetil, Bottini, Nunzio, Zavattari, Patrizia, Macis, Maria Doloretta, Cucca, Francesco, Vang, Torkel, Orrú, Valeria, Congia, Mauro, Nika, Konstantina
Published in Nature genetics (01.12.2005)
Published in Nature genetics (01.12.2005)
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PTP4A1 promotes TGFβ signaling and fibrosis in systemic sclerosis
Sacchetti, Cristiano, Bai, Yunpeng, Stanford, Stephanie M., Di Benedetto, Paola, Cipriani, Paola, Santelli, Eugenio, Piera-Velazquez, Sonsoles, Chernitskiy, Vladimir, Kiosses, William B., Ceponis, Arnold, Kaestner, Klaus H., Boin, Francesco, Jimenez, Sergio A., Giacomelli, Roberto, Zhang, Zhong-Yin, Bottini, Nunzio
Published in Nature communications (20.10.2017)
Published in Nature communications (20.10.2017)
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Journal Article
CD45-mediated control of TCR tuning in naïve and memory CD8+ T cells
Cho, Jae-Ho, Kim, Hee-Ok, Ju, Young-Jun, Kye, Yoon-Chul, Lee, Gil-Woo, Lee, Sung-Woo, Yun, Cheol-Heui, Bottini, Nunzio, Webster, Kylie, Goodnow, Christopher C., Surh, Charles D., King, Cecile, Sprent, Jonathan
Published in Nature communications (14.11.2016)
Published in Nature communications (14.11.2016)
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Journal Article
Integration of T helper and BCR signals governs enhanced plasma cell differentiation of memory B cells by regulation of CD45 phosphatase activity
Szodoray, Peter, Andersen, Tor Kristian, Heinzelbecker, Julia, Imbery, John F., Huszthy, Peter C., Stanford, Stephanie M., Bogen, Bjarne, Landsverk, Ole B., Bottini, Nunzio, Tveita, Anders, Munthe, Ludvig A., Nakken, Britt
Published in Cell reports (Cambridge) (10.08.2021)
Published in Cell reports (Cambridge) (10.08.2021)
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Journal Article
T-helper signals restore B-cell receptor signaling in autoreactive anergic B cells by upregulating CD45 phosphatase activity
Szodoray, Peter, MD, PhD, Stanford, Stephanie M., PhD, Molberg, Øyvind, MD, PhD, Munthe, Ludvig A., MD, PhD, Bottini, Nunzio, MD, PhD, Nakken, Britt, PhD
Published in Journal of allergy and clinical immunology (01.09.2016)
Published in Journal of allergy and clinical immunology (01.09.2016)
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Journal Article
Targeting phosphatase-dependent proteoglycan switch for rheumatoid arthritis therapy
Doody, Karen M, Stanford, Stephanie M, Sacchetti, Cristiano, Svensson, Mattias N D, Coles, Charlotte H, Mitakidis, Nikolaos, Kiosses, William B, Bartok, Beatrix, Fos, Camille, Cory, Esther, Sah, Robert L, Liu-Bryan, Ru, Boyle, David L, Arnett, Heather A, Mustelin, Tomas, Corr, Maripat, Esko, Jeffrey D, Tremblay, Michel L, Firestein, Gary S, Aricescu, A Radu, Bottini, Nunzio
Published in Science translational medicine (20.05.2015)
Published in Science translational medicine (20.05.2015)
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Journal Article
Gold(I)-Mediated Inhibition of Protein Tyrosine Phosphatases: A Detailed in Vitro and Cellular Study
Krishnamurthy, Divya, Karver, Mark R, Fiorillo, Edoardo, Orrú, Valeria, Stanford, Stephanie M, Bottini, Nunzio, Barrios, Amy M
Published in Journal of medicinal chemistry (14.08.2008)
Published in Journal of medicinal chemistry (14.08.2008)
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