Protein kinase A negatively regulates Ca2+ signalling in Toxoplasma gondii
Uboldi, Alessandro D, Wilde, Mary-Louise, McRae, Emi A, Stewart, Rebecca J, Dagley, Laura F, Yang, Luning, Katris, Nicholas J, Hapuarachchi, Sanduni V, Coffey, Michael J, Lehane, Adele M, Botte, Cyrille Y, Waller, Ross F, Webb, Andrew I, McConville, Malcolm J, Tonkin, Christopher J
Published in PLoS biology (01.09.2018)
Published in PLoS biology (01.09.2018)
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The apicoplast: a key target to cure malaria
MacRae, James I, Maréchal, Eric, Biot, Christophe, Botté, Cyrille Y
Published in Current pharmaceutical design (2012)
Published in Current pharmaceutical design (2012)
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Discovery of Compounds Blocking the Proliferation of Toxoplasma gondii and Plasmodium falciparum in a Chemical Space Based on Piperidinyl-Benzimidazolone Analogs
SAÏDANI, Nadia, BOTTE, Cyrille Y, ROUSSEAU, Bernard, BIRKHOLTZ, Lyn-Marie, CESBRON-DELAUW, Marie-France, DUBREMETZ, Jean-François, MERCIER, Corinne, VIAL, Henri, LOPEZ, Roman, MARECHAL, Eric, DELIGNY, Michael, BONNEAU, Anne-Laure, READER, Janette, LASSELIN, Ronald, MERER, Goulven, NIEPCERON, Alisson, BROSSIER, Fabien, CINTRAT, Jean-Christophe
Published in Antimicrobial agents and chemotherapy (01.05.2014)
Published in Antimicrobial agents and chemotherapy (01.05.2014)
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The flexibility of Apicomplexa parasites in lipid metabolism
Shunmugam, Serena, Arnold, Christophe-Sébastien, Dass, Sheena, Katris, Nicholas J, Botté, Cyrille Y
Published in PLoS pathogens (17.03.2022)
Published in PLoS pathogens (17.03.2022)
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Journal Article
Phosphatidic Acid-Mediated Signaling Regulates Microneme Secretion in Toxoplasma
Bullen, Hayley E., Jia, Yonggen, Yamaryo-Botté, Yoshiki, Bisio, Hugo, Zhang, Ou, Jemelin, Natacha Klages, Marq, Jean-Baptiste, Carruthers, Vern, Botté, Cyrille Y., Soldati-Favre, Dominique
Published in Cell host & microbe (09.03.2016)
Published in Cell host & microbe (09.03.2016)
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Journal Article
Toxoplasma metabolic flexibility in different growth conditions
Walsh, Daniel, Katris, Nicholas J., Sheiner, Lilach, Botté, Cyrille Y.
Published in Trends in parasitology (01.09.2022)
Published in Trends in parasitology (01.09.2022)
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Toxoplasma gondii acetyl-CoA synthetase is involved in fatty acid elongation (of long fatty acid chains) during tachyzoite life stages
Dubois, David, Fernandes, Stella, Amiar, Souad, Dass, Sheena, Katris, Nicholas J., Botté, Cyrille Y., Yamaryo-Botté, Yoshiki
Published in Journal of lipid research (01.06.2018)
Published in Journal of lipid research (01.06.2018)
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Disrupting the plastidic iron-sulfur cluster biogenesis pathway in Toxoplasma gondii has pleiotropic effects irreversibly impacting parasite viability
Renaud, Eléa A., Pamukcu, Sarah, Cerutti, Aude, Berry, Laurence, Lemaire-Vieille, Catherine, Yamaryo-Botté, Yoshiki, Botté, Cyrille Y., Besteiro, Sébastien
Published in The Journal of biological chemistry (01.08.2022)
Published in The Journal of biological chemistry (01.08.2022)
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Toxoplasma acyl-CoA synthetase TgACS3 is crucial to channel host fatty acids in lipid droplets and for parasite propagation
Dass, Sheena, Shunmugam, Serena, Charital, Sarah, Duley, Samuel, Arnold, Christophe-Sébastien, Katris, Nicholas J., Cavaillès, Pierre, Cesbron-Delauw, Marie-France, Yamaryo-Botté, Yoshiki, Botté, Cyrille Y.
Published in Journal of lipid research (01.10.2024)
Published in Journal of lipid research (01.10.2024)
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Fatty acid metabolism in the Plasmodium apicoplast: Drugs, doubts and knockouts
Shears, Melanie J., Botté, Cyrille Y., McFadden, Geoffrey I.
Published in Molecular and biochemical parasitology (01.01.2015)
Published in Molecular and biochemical parasitology (01.01.2015)
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An essential vesicular-trafficking phospholipase mediates neutral lipid synthesis and contributes to hemozoin formation in Plasmodium falciparum
Asad, Mohd, Yamaryo-Botté, Yoshiki, Hossain, Mohammad E, Thakur, Vandana, Jain, Shaifali, Datta, Gaurav, Botté, Cyrille Y, Mohmmed, Asif
Published in BMC biology (11.08.2021)
Published in BMC biology (11.08.2021)
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A positive feedback loop mediates crosstalk between calcium, cyclic nucleotide and lipid signalling in calcium-induced Toxoplasma gondii egress
Nofal, Stephanie D, Dominicus, Caia, Broncel, Malgorzata, Katris, Nicholas J, Flynn, Helen R, Arrizabalaga, Gustavo, Botté, Cyrille Y, Invergo, Brandon M, Treeck, Moritz
Published in PLoS pathogens (01.10.2022)
Published in PLoS pathogens (01.10.2022)
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Lipid profile remodeling in response to nitrogen deprivation in the microalgae Chlorella sp. (Trebouxiophyceae) and Nannochloropsis sp. (Eustigmatophyceae)
Martin, Gregory J O, Hill, David R A, Olmstead, Ian L D, Bergamin, Amanda, Shears, Melanie J, Dias, Daniel A, Kentish, Sandra E, Scales, Peter J, Botté, Cyrille Y, Callahan, Damien L
Published in PloS one (29.08.2014)
Published in PloS one (29.08.2014)
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Toxoplasma LIPIN is essential in channeling host lipid fluxes through membrane biogenesis and lipid storage
Dass, Sheena, Shunmugam, Serena, Berry, Laurence, Arnold, Christophe-Sebastien, Katris, Nicholas J., Duley, Samuel, Pierrel, Fabien, Cesbron-Delauw, Marie-France, Yamaryo-Botté, Yoshiki, Botté, Cyrille Y.
Published in Nature communications (17.05.2021)
Published in Nature communications (17.05.2021)
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CRISPR Screens Identify Toxoplasma Genes That Determine Parasite Fitness in Interferon Gamma-Stimulated Human Cells
Krishnamurthy, Shruthi, Maru, Parag, Wang, Yifan, Bitew, Mebratu A, Mukhopadhyay, Debanjan, Yamaryo-Botté, Yoshiki, Paredes-Santos, Tatiana C, Sangaré, Lamba O, Swale, Christopher, Botté, Cyrille Y, Saeij, Jeroen P J
Published in mBio (25.04.2023)
Published in mBio (25.04.2023)
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Journal Article
Protein kinase TgCDPK7 regulates vesicular trafficking and phospholipid synthesis in Toxoplasma gondii
Bansal, Priyanka, Antil, Neelam, Kumar, Manish, Yamaryo-Botté, Yoshiki, Rawat, Rahul Singh, Pinto, Sneha, Datta, Keshava K, Katris, Nicholas J, Botté, Cyrille Y, Prasad, T S Keshava, Sharma, Pushkar
Published in PLoS pathogens (01.02.2021)
Published in PLoS pathogens (01.02.2021)
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Journal Article
Division and Adaptation to Host Environment of Apicomplexan Parasites Depend on Apicoplast Lipid Metabolic Plasticity and Host Organelle Remodeling
Amiar, Souad, Katris, Nicholas J., Berry, Laurence, Dass, Sheena, Duley, Samuel, Arnold, Christophe-Sebastien, Shears, Melanie J., Brunet, Camille, Touquet, Bastien, McFadden, Geoffrey I., Yamaryo-Botté, Yoshiki, Botté, Cyrille Y.
Published in Cell reports (Cambridge) (17.03.2020)
Published in Cell reports (Cambridge) (17.03.2020)
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Journal Article
Plasmodium falciparum Apicoplast Drugs: Targets or Off-Targets?
Botté, Cyrille Y, Dubar, Faustine, McFadden, Geoffrey I, Maréchal, Eric, Biot, Christophe
Published in Chemical reviews (14.03.2012)
Published in Chemical reviews (14.03.2012)
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