Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway
Chen, Sisi, Wang, Qiang, Yu, Hao, Capitano, Maegan L, Vemula, Sasidhar, Nabinger, Sarah C, Gao, Rui, Yao, Chonghua, Kobayashi, Michihiro, Geng, Zhuangzhuang, Fahey, Aidan, Henley, Danielle, Liu, Stephen Z, Barajas, Sergio, Cai, Wenjie, Wolf, Eric R, Ramdas, Baskar, Cai, Zhigang, Gao, Hongyu, Luo, Na, Sun, Yang, Wong, Terrence N, Link, Daniel C, Liu, Yunlong, Boswell, H Scott, Mayo, Lindsey D, Huang, Gang, Kapur, Reuben, Yoder, Mervin C, Broxmeyer, Hal E, Gao, Zhonghua, Liu, Yan
Published in Nature communications (11.12.2019)
Published in Nature communications (11.12.2019)
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Mutant p53 enhances leukemia-initiating cell self-renewal to promote leukemia development
Nabinger, Sarah C, Chen, Sisi, Gao, Rui, Yao, Chonghua, Kobayashi, Michihiro, Vemula, Sasidhar, Fahey, Aidan C, Wang, Christine, Daniels, Cecil, Boswell, H Scott, Sandusky, George E, Mayo, Lindsey D, Kapur, Reuben, Liu, Yan
Published in Leukemia (01.06.2019)
Published in Leukemia (01.06.2019)
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Rho Kinase Regulates the Survival and Transformation of Cells Bearing Oncogenic Forms of KIT, FLT3, and BCR-ABL
Mali, Raghuveer Singh, Ramdas, Baskar, Ma, Peilin, Shi, Jianjian, Munugalavadla, Veerendra, Sims, Emily, Wei, Lei, Vemula, Sasidhar, Nabinger, Sarah C., Goodwin, Charles B., Chan, Rebecca J., Traina, Fabiola, Visconte, Valeria, Tiu, Ramon V., Lewis, Timothy A., Stern, Andrew M., Wen, Qiang, Crispino, John D., Boswell, H. Scott, Kapur, Reuben
Published in Cancer cell (13.09.2011)
Published in Cancer cell (13.09.2011)
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Regulation of Stat5 by FAK and PAK1 in Oncogenic FLT3- and KIT-Driven Leukemogenesis
Chatterjee, Anindya, Ghosh, Joydeep, Ramdas, Baskar, Mali, Raghuveer Singh, Martin, Holly, Kobayashi, Michihiro, Vemula, Sasidhar, Canela, Victor H., Waskow, Emily R., Visconte, Valeria, Tiu, Ramon V., Smith, Catherine C., Shah, Neil, Bunting, Kevin D., Boswell, H. Scott, Liu, Yan, Chan, Rebecca J., Kapur, Reuben
Published in Cell reports (Cambridge) (20.11.2014)
Published in Cell reports (Cambridge) (20.11.2014)
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Author Correction: Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway
Chen, Sisi, Wang, Qiang, Yu, Hao, Capitano, Maegan L., Vemula, Sasidhar, Nabinger, Sarah C., Gao, Rui, Yao, Chonghua, Kobayashi, Michihiro, Geng, Zhuangzhuang, Fahey, Aidan, Henley, Danielle, Liu, Stephen Z., Barajas, Sergio, Cai, Wenjie, Wolf, Eric R., Ramdas, Baskar, Cai, Zhigang, Gao, Hongyu, Luo, Na, Sun, Yang, Wong, Terrence N., Link, Daniel C., Liu, Yunlong, Boswell, H. Scott, Mayo, Lindsey D., Huang, Gang, Kapur, Reuben, Yoder, Mervin C., Broxmeyer, Hal E., Gao, Zhonghua, Liu, Yan
Published in Nature communications (28.07.2020)
Published in Nature communications (28.07.2020)
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Survivin mediates aberrant hematopoietic progenitor cell proliferation and acute leukemia in mice induced by internal tandem duplication of Flt3
Fukuda, Seiji, Singh, Pratibha, Moh, Akira, Abe, Mariko, Conway, Edward M., Boswell, H. Scott, Yamaguchi, Seiji, Fu, Xin-Yuan, Pelus, Louis M.
Published in Blood (09.07.2009)
Published in Blood (09.07.2009)
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Consecutive epigenetically-active agent combinations act in ID1-RUNX3-TET2 and HOXA pathways for Flt3ITD+ve AML
Sayar, Hamid, Liu, Yan, Gao, Rui, Zaid, Mohammad Abu, Cripe, Larry D, Weisenbach, Jill, Sargent, Katie J, Nassiri, Mehdi, Li, Lang, Konig, Heiko, Suvannasankha, Attaya, Pan, Feng, Shanmugam, Rajasubramaniam, Goswami, Chirayu, Kapur, Reuben, Xu, Mingjiang, Boswell, H Scott
Published in Oncotarget (19.01.2018)
Published in Oncotarget (19.01.2018)
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Novel Combination Treatments Targeting Chronic Myeloid Leukemia Stem Cells
Al Baghdadi, Tareq, Abonour, Rafat, Boswell, H. Scott
Published in Clinical lymphoma, myeloma and leukemia (01.04.2012)
Published in Clinical lymphoma, myeloma and leukemia (01.04.2012)
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Notch-Dependent Repression of miR-155 in the Bone Marrow Niche Regulates Hematopoiesis in an NF-κB-Dependent Manner
Wang, Lin, Zhang, Huajia, Rodriguez, Sonia, Cao, Liyun, Parish, Jonathan, Mumaw, Christen, Zollman, Amy, Kamoka, Malgorzata M., Mu, Jian, Chen, Danny Z., Srour, Edward F., Chitteti, Brahmananda R., HogenEsch, Harm, Tu, Xiaolin, Bellido, Teresita M., Boswell, H. Scott, Manshouri, Taghi, Verstovsek, Srdan, Yoder, Mervin C., Kapur, Reuben, Cardoso, Angelo A., Carlesso, Nadia
Published in Cell stem cell (03.07.2014)
Published in Cell stem cell (03.07.2014)
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Role for c-jun N-terminal kinase in treatment-refractory acute myeloid leukemia (AML): signaling to multidrug-efflux and hyperproliferation
CRIPE, L. D, GELFANOV, V. M, MERCOLA, D, BURGESS, G. S, BOSWELL, H. Scott, SMITH, E. A, SPIGEL, D. R, PHILLIPS, C. A, GABIG, T. G, JUNG, S-H, FYFFE, J, HARTMAN, A. D, KNEEBONE, P
Published in Leukemia (01.05.2002)
Published in Leukemia (01.05.2002)
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PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371
Chen, Hongxia, Bai, Yunpeng, Kobayashi, Michihiro, Xiao, Shiyu, Cai, Wenjie, Barajas, Sergio, Chen, Sisi, Miao, Jinmin, Meke, Frederick Nguele, Vemula, Sasidhar, Ropa, James P., Croop, James M., Boswell, H. Scott, Wan, Jun, Jia, Yuzhi, Liu, Huiping, Li, Loretta S., Altman, Jessica K., Eklund, Elizabeth A., Ji, Peng, Tong, Wei, Band, Hamid, Huang, Danny T., Platanias, Leonidas C., Zhang, Zhong-Yin, Liu, Yan
Published in Blood (19.01.2023)
Published in Blood (19.01.2023)
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Classic and targeted anti‐leukaemic agents interfere with the cholesterol biogenesis metagene in acute myeloid leukaemia: Therapeutic implications
Chen, Fangli, Wu, Xue, Niculite, Cristina, Gilca, Marilena, Petrusca, Daniela, Rogozea, Adriana, Rice, Susan, Guo, Bin, Griffin, Shawn, Calin, George A., Boswell, H. Scott, Konig, Heiko
Published in Journal of cellular and molecular medicine (01.07.2020)
Published in Journal of cellular and molecular medicine (01.07.2020)
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Pharmacological inhibition of Carbonic Anhydrase IX and XII to enhance targeting of acute myeloid leukaemia cells under hypoxic conditions
Chen, Fangli, Licarete, Emilia, Wu, Xue, Petrusca, Daniela, Maguire, Callista, Jacobsen, Max, Colter, Austyn, Sandusky, George E., Czader, Magdalena, Capitano, Maegan L., Ropa, James P., Boswell, H. Scott, Carta, Fabrizio, Supuran, Claudiu T., Parkin, Brian, Fishel, Melissa L., Konig, Heiko
Published in Journal of cellular and molecular medicine (01.12.2021)
Published in Journal of cellular and molecular medicine (01.12.2021)
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Combination of sorafenib, vorinostat and bortezomib for the treatment of poor-risk AML: report of two consecutive clinical trials
Sayar, Hamid, Cripe, Larry D., Saliba, Antoine N., Abu Zaid, Mohammad, Konig, Heiko, Boswell, H. Scott
Published in Leukemia research (01.02.2019)
Published in Leukemia research (01.02.2019)
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PRL2 Phosphatase Promotes Oncogenic KIT Signaling in Leukemia Cells through Modulating CBL Phosphorylation
Chen, Hongxia, Bai, Yunpeng, Kobayashi, Michihiro, Xiao, Shiyu, Barajas, Sergio, Cai, Wenjie, Chen, Sisi, Miao, Jinmin, Nguele Meke, Frederick, Yao, Chonghua, Yang, Yuxia, Strube, Katherine, Satchivi, Odelia, Sun, Jianmin, Rönnstrand, Lars, Croop, James M, Boswell, H Scott, Jia, Yuzhi, Liu, Huiping, Li, Loretta S, Altman, Jessica K, Eklund, Elizabeth A, Sukhanova, Madina, Ji, Peng, Tong, Wei, Band, Hamid, Huang, Danny T, Platanias, Leonidas C, Zhang, Zhong-Yin, Liu, Yan
Published in Molecular cancer research (02.01.2024)
Published in Molecular cancer research (02.01.2024)
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Death-associated Protein Kinase-1 Expression and Autophagy in Chronic Lymphocytic Leukemia Are Dependent on Activating Transcription Factor-6 and CCAAT/Enhancer-binding Protein-β
Gade, Padmaja, Kimball, Amy S, DiNardo, Angela C, Gangwal, Priyamvada, Ross, Douglas D, Boswell, H Scott, Keay, Susan K, Kalvakolanu, Dhananjaya V
Published in The Journal of biological chemistry (14.10.2016)
Published in The Journal of biological chemistry (14.10.2016)
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A Noncanonical Flt3ITD/NF-κB Signaling Pathway Represses DAPK1 in Acute Myeloid Leukemia
SHANMUGAM, Rajasubramaniam, GADE, Padmaja, SARGENT, Katie J, CRIPE, Larry D, KALVAKOLANU, Dhananjaya V, BOSWELL, H. Scott, WILSON-WEEKES, Annique, SAYAR, Hamid, SUVANNASANKHA, Attaya, GOSWAMI, Chirayu, LANG LI, GUPTA, Sushil, CARDOSO, Angelo A, BAGHDADI, Tareq Al
Published in Clinical cancer research (15.01.2012)
Published in Clinical cancer research (15.01.2012)
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Paclitaxel sensitivity of breast cancer cells with constitutively active NF-κB is enhanced by IκBα super-repressor and parthenolide
Patel, Nikhil M, Nozaki, Shinichi, Shortle, Nicholas H, Bhat-Nakshatri, Poornima, Newton, Thomas R, Rice, Susan, Gelfanov, Vasily, Boswell, Scott H, Goulet, Robert J, Sledge, George W, Nakshatri, Harikrishna
Published in Oncogene (24.08.2000)
Published in Oncogene (24.08.2000)
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Constitutive c-jun N-terminal kinase activity in acute myeloid leukemia derives from Flt3 and affects survival and proliferation
Hartman, Amy D., Wilson-Weekes, Annique, Suvannasankha, Attaya, Burgess, Gem S., Phillips, Carissa A., Hincher, Katie J., Cripe, Larry D., Boswell, H. Scott
Published in Experimental hematology (01.10.2006)
Published in Experimental hematology (01.10.2006)
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