Discovery of Clinically Approved Agents That Promote Suppression of Cystic Fibrosis Transmembrane Conductance Regulator Nonsense Mutations
Mutyam, Venkateshwar, Du, Ming, Xue, Xiaojiao, Keeling, Kim M, White, E Lucile, Bostwick, J Robert, Rasmussen, Lynn, Liu, Bo, Mazur, Marina, Hong, Jeong S, Falk Libby, Emily, Liang, Feng, Shang, Haibo, Mense, Martin, Suto, Mark J, Bedwell, David M, Rowe, Steven M
Published in American journal of respiratory and critical care medicine (01.11.2016)
Published in American journal of respiratory and critical care medicine (01.11.2016)
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Targeting EMT using low-dose Teniposide by downregulating ZEB2-driven activation of RNA polymerase I in breast cancer
Metge, Brandon J., Alsheikh, Heba Allah M., Kammerud, Sarah C., Chen, Dongquan, Das, Devika, Nebane, N. Miranda, Bostwick, J. Robert, Shevde, Lalita A., Samant, Rajeev S.
Published in Cell death & disease (08.05.2024)
Published in Cell death & disease (08.05.2024)
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Discovery of a novel inhibitor of kinesin-like protein KIFC1
Zhang, Wei, Zhai, Ling, Wang, Yimin, Boohaker, Rebecca J, Lu, Wenyan, Gupta, Vandana V, Padmalayam, Indira, Bostwick, Robert J, White, E Lucile, Ross, Larry J, Maddry, Joseph, Ananthan, Subramaniam, Augelli-Szafran, Corinne E, Suto, Mark J, Xu, Bo, Li, Rongbao, Li, Yonghe
Published in Biochemical journal (15.04.2016)
Published in Biochemical journal (15.04.2016)
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A high-throughput response to the SARS-CoV-2 pandemic
Rasmussen, Lynn, Sanders, Shalisa, Sosa, Melinda, McKellip, Sara, Nebane, N. Miranda, Martinez-Gzegozewska, Yohanka, Reece, Andrew, Ruiz, Pedro, Manuvakhova, Anna, Zhai, Ling, Warren, Brooke, Curry, Aliyah, Zeng, Qinghua, Bostwick, J. Robert, Vinson, Paige N.
Published in SLAS discovery (01.07.2024)
Published in SLAS discovery (01.07.2024)
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A small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion
Sharma, Jyoti, Du, Ming, Wong, Eric, Mutyam, Venkateshwar, Li, Yao, Chen, Jianguo, Wangen, Jamie, Thrasher, Kari, Fu, Lianwu, Peng, Ning, Tang, Liping, Liu, Kaimao, Mathew, Bini, Bostwick, Robert J., Augelli-Szafran, Corinne E., Bihler, Hermann, Liang, Feng, Mahiou, Jerome, Saltz, Josef, Rab, Andras, Hong, Jeong, Sorscher, Eric J., Mendenhall, Eric M., Coppola, Candice J., Keeling, Kim M., Green, Rachel, Mense, Martin, Suto, Mark J., Rowe, Steven M., Bedwell, David M.
Published in Nature communications (16.07.2021)
Published in Nature communications (16.07.2021)
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Discovery and Pharmacological Characterization of a Small-Molecule Antagonist at Neuromedin U Receptor NMUR2
Liu, Jay J, Payza, Kemal, Huang, Jian, Liu, Ruifeng, Chen, Tongming, Coupal, Martin, Laird, Jennifer M A, Cao, Chang-Qing, Butterworth, Joanne, Lapointe, Stéphanie, Bayrakdarian, Malken, Trivedi, Shephali, Bostwick, J Robert
Published in The Journal of pharmacology and experimental therapeutics (01.07.2009)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2009)
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Development of small-molecule Tau-SH3 interaction inhibitors that prevent amyloid-β toxicity and network hyperexcitability
Roth, Jonathan R., Rush, Travis, Thompson, Samantha J., Aldaher, Adam R., Dunn, Trae B., Mesina, Jacob S., Cochran, J. Nicholas, Boyle, Nicholas R., Dean, Hunter B., Yang, Zhengrong, Pathak, Vibha, Ruiz, Pedro, Wu, Mousheng, Day, Jeremy J., Bostwick, J. Robert, Suto, Mark J., Augelli-Szafran, Corinne E., Roberson, Erik D.
Published in Neurotherapeutics (01.01.2024)
Published in Neurotherapeutics (01.01.2024)
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Identification of Quinolinones as Antivirals against Venezuelan Equine Encephalitis Virus
Haese, Nicole N, May, Nicholas A, Taft-Benz, Sharon, Moukha-Chafiq, Omar, Madadi, Nikhil, Zhang, Sixue, Karyakarte, Shuklendu D, Rodzinak, Kevin J, Nguyen, Theresa H, Denton, Michael, Streblow, Aaron D, Towers, Nichole A, Rasmussen, Lynn, Bostwick, Robert J, Maddry, Joseph A, Ananthan, Subramaniam, Augelli-Szafran, Corinne E, Suto, Mark J, Sanders, Wes, Moorman, Nathaniel, DeFilippis, Victor, Heise, Mark T, Pathak, Ashish K, Streblow, Daniel N, Morrison, Thomas E
Published in Antimicrobial agents and chemotherapy (17.08.2021)
Published in Antimicrobial agents and chemotherapy (17.08.2021)
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Design, Synthesis, and Structure–Activity Relationship Studies of a Series of [4-(4-Carboxamidobutyl)]-1-arylpiperazines: Insights into Structural Features Contributing to Dopamine D3 versus D2 Receptor Subtype Selectivity
Ananthan, Subramaniam, Saini, Surendra K, Zhou, Guangyan, Hobrath, Judith V, Padmalayam, Indira, Zhai, Ling, Bostwick, J. Robert, Antonio, Tamara, Reith, Maarten E. A, McDowell, Shea, Cho, Eunie, McAleer, Leah, Taylor, Michelle, Luedtke, Robert R
Published in Journal of medicinal chemistry (28.08.2014)
Published in Journal of medicinal chemistry (28.08.2014)
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Triamterene normalizes glycosaminoglycan accumulation in an IDUA-W402X mouse model of MPS I (Hurler syndrome) via nonsense suppression
Bedwell, David, Siddiqui, Amna, Dundar, Halil, Echols, Josh, Du, Ming, Rasmussen, Lynn, Robert Bostwick, J., Suto, Mark, Keeling, Kim
Published in Molecular genetics and metabolism (01.02.2019)
Published in Molecular genetics and metabolism (01.02.2019)
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Development of small‐molecule tau‐SH3 interaction inhibitors that prevent amyloid‐β toxicity
Roth, Jonathan R, Rush, Travis, Pugh, Derian A, Dean, Hunter B, Cochran, J. Nicholas, Thompson, Samantha J, Aldaher, Adam R, Mesina, Jacob S, Ruiz, Pedro, Pathak, Vibha, Wu, Mousheng, Bostwick, J Robert, Suto, Mark J, Augelli‐Szafran, Corinne E, Roberson, Erik D.
Published in Alzheimer's & dementia (01.12.2021)
Published in Alzheimer's & dementia (01.12.2021)
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Abstract 1746: Discovery and evaluation of a small molecule KIFC1 inhibitor for breast cancer treatment
Zhang, Wei, Zhai, Ling, Lu, Wenyan, Wang, Yimin, Gupta, Vandana V., Padmalayam, Indira, Bostwick, Robert J., White, Lucile, Larry, Ross, Maddry, Joseph, Ananthan, Sam, Suto, Mark, Xu, Bo, Li, Rongbao, Li, Yonghe
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Determination of protein by a modified Lowry procedure in the presence of some commonly used detergents
Cadman, Evelyn, Bostwick, J.Robert, Eichberg, Joseph
Published in Analytical biochemistry (01.07.1979)
Published in Analytical biochemistry (01.07.1979)
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