Rapid Inflammasome Activation following Mucosal SIV Infection of Rhesus Monkeys
Barouch, Dan H., Ghneim, Khader, Bosche, William J., Li, Yuan, Berkemeier, Brian, Hull, Michael, Bhattacharyya, Sanghamitra, Cameron, Mark, Liu, Jinyan, Smith, Kaitlin, Borducchi, Erica, Cabral, Crystal, Peter, Lauren, Brinkman, Amanda, Shetty, Mayuri, Li, Hualin, Gittens, Courtney, Baker, Chantelle, Wagner, Wendeline, Lewis, Mark G., Colantonio, Arnaud, Kang, Hyung-Joo, Li, Wenjun, Lifson, Jeffrey D., Piatak, Michael, Sekaly, Rafick-Pierre
Published in Cell (21.04.2016)
Published in Cell (21.04.2016)
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Genetically-barcoded SIV facilitates enumeration of rebound variants and estimation of reactivation rates in nonhuman primates following interruption of suppressive antiretroviral therapy
Fennessey, Christine M, Pinkevych, Mykola, Immonen, Taina T, Reynaldi, Arnold, Venturi, Vanessa, Nadella, Priyanka, Reid, Carolyn, Newman, Laura, Lipkey, Leslie, Oswald, Kelli, Bosche, William J, Trivett, Matthew T, Ohlen, Claes, Ott, David E, Estes, Jacob D, Del Prete, Gregory Q, Lifson, Jeffrey D, Davenport, Miles P, Keele, Brandon F
Published in PLoS pathogens (04.05.2017)
Published in PLoS pathogens (04.05.2017)
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Early antiretroviral therapy limits SIV reservoir establishment to delay or prevent post-treatment viral rebound
Okoye, Afam A, Hansen, Scott G, Vaidya, Mukta, Fukazawa, Yoshinori, Park, Haesun, Duell, Derick M, Lum, Richard, Hughes, Colette M, Ventura, Abigail B, Ainslie, Emily, Ford, Julia C, Morrow, David, Gilbride, Roxanne M, Legasse, Alfred W, Hesselgesser, Joseph, Geleziunas, Romas, Li, Yuan, Oswald, Kelli, Shoemaker, Rebecca, Fast, Randy, Bosche, William J, Borate, Bhavesh R, Edlefsen, Paul T, Axthelm, Michael K, Picker, Louis J, Lifson, Jeffrey D
Published in Nature medicine (01.09.2018)
Published in Nature medicine (01.09.2018)
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Journal Article
A live-attenuated RhCMV/SIV vaccine shows long-term efficacy against heterologous SIV challenge
Hansen, Scott G, Marshall, Emily E, Malouli, Daniel, Ventura, Abigail B, Hughes, Colette M, Ainslie, Emily, Ford, Julia C, Morrow, David, Gilbride, Roxanne M, Bae, Jin Y, Legasse, Alfred W, Oswald, Kelli, Shoemaker, Rebecca, Berkemeier, Brian, Bosche, William J, Hull, Michael, Womack, Jennie, Shao, Jason, Edlefsen, Paul T, Reed, Jason S, Burwitz, Ben J, Sacha, Jonah B, Axthelm, Michael K, Früh, Klaus, Lifson, Jeffrey D, Picker, Louis J
Published in Science translational medicine (17.07.2019)
Published in Science translational medicine (17.07.2019)
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Impact of alemtuzumab-mediated lymphocyte depletion on SIV reservoir establishment and persistence
Varco-Merth, Benjamin, Chaunzwa, Morgan, Duell, Derick M, Marenco, Alejandra, Goodwin, William, Dannay, Rachel, Nekorchuk, Michael, Shao, Danica, Busman-Sahay, Kathleen, Fennessey, Christine M, Silipino, Lorna, Hull, Michael, Bosche, William J, Fast, Randy, Oswald, Kelli, Shoemaker, Rebecca, Bochart, Rachele, MacAllister, Rhonda, Labriola, Caralyn S, Smedley, Jeremy V, Axthelm, Michael K, Davenport, Miles P, Edlefsen, Paul T, Estes, Jacob D, Keele, Brandon F, Lifson, Jeffrey D, Lewin, Sharon R, Picker, Louis J, Okoye, Afam A
Published in PLoS pathogens (22.08.2024)
Published in PLoS pathogens (22.08.2024)
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Early antiretroviral therapy in SIV-infected rhesus macaques reveals a multiphasic, saturable dynamic accumulation of the rebound competent viral reservoir
Keele, Brandon F, Okoye, Afam A, Fennessey, Christine M, Varco-Merth, Benjamin, Immonen, Taina T, Kose, Emek, Conchas, Andrew, Pinkevych, Mykola, Lipkey, Leslie, Newman, Laura, Macairan, Agatha, Bosche, Marjorie, Bosche, William J, Berkemeier, Brian, Fast, Randy, Hull, Mike, Oswald, Kelli, Shoemaker, Rebecca, Silipino, Lorna, Gorelick, Robert J, Duell, Derick, Marenco, Alejandra, Brantley, William, Smedley, Jeremy, Axthelm, Michael, Davenport, Miles P, Lifson, Jeffrey D, Picker, Louis J
Published in PLoS pathogens (09.04.2024)
Published in PLoS pathogens (09.04.2024)
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The ability of TNPO3-depleted cells to inhibit HIV-1 infection requires CPSF6
Fricke, Thomas, Valle-Casuso, Jose Carlos, White, Tommy E, Brandariz-Nuñez, Alberto, Bosche, William J, Reszka, Natalia, Gorelick, Robert, Diaz-Griffero, Felipe
Published in Retrovirology (26.04.2013)
Published in Retrovirology (26.04.2013)
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Liver macrophage-associated inflammation correlates with SIV burden and is substantially reduced following cART
Fisher, Bridget S, Green, Richard R, Brown, Rachel R, Wood, Matthew P, Hensley-McBain, Tiffany, Fisher, Cole, Chang, Jean, Miller, Andrew D, Bosche, William J, Lifson, Jeffrey D, Mavigner, Maud, Miller, Charlene J, Gale, Jr, Michael, Silvestri, Guido, Chahroudi, Ann, Klatt, Nichole R, Sodora, Donald L
Published in PLoS pathogens (01.02.2018)
Published in PLoS pathogens (01.02.2018)
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Journal Article
Antibody-mediated protection against SHIV challenge includes systemic clearance of distal virus
Liu, Jinyan, Ghneim, Khader, Sok, Devin, Bosche, William J., Li, Yuan, Chipriano, Elizabeth, Berkemeier, Brian, Oswald, Kelli, Borducchi, Erica, Cabral, Crystal, Peter, Lauren, Brinkman, Amanda, Shetty, Mayuri, Jimenez, Jessica, Mondesir, Jade, Lee, Benjamin, Giglio, Patricia, Chandrashekar, Abishek, Abbink, Peter, Colantonio, Arnaud, Gittens, Courtney, Baker, Chantelle, Wagner, Wendeline, Lewis, Mark G., Li, Wenjun, Sekaly, Rafick-Pierre, Lifson, Jeffrey D., Burton, Dennis R., Barouch, Dan H.
Published in Science (American Association for the Advancement of Science) (02.09.2016)
Published in Science (American Association for the Advancement of Science) (02.09.2016)
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Journal Article
Modulation of MHC-E transport by viral decoy ligands is required for RhCMV/SIV vaccine efficacy
Verweij, Marieke C, Hansen, Scott G, Iyer, Ravi, John, Nessy, Malouli, Daniel, Morrow, David, Scholz, Isabel, Womack, Jennie, Abdulhaqq, Shaheed, Gilbride, Roxanne M, Hughes, Colette M, Ventura, Abigail B, Ford, Julia C, Selseth, Andrea N, Oswald, Kelli, Shoemaker, Rebecca, Berkemeier, Brian, Bosche, William J, Hull, Michael, Shao, Jason, Sacha, Jonah B, Axthelm, Michael K, Edlefsen, Paul T, Lifson, Jeffrey D, Picker, Louis J, Früh, Klaus
Published in Science (American Association for the Advancement of Science) (30.04.2021)
Published in Science (American Association for the Advancement of Science) (30.04.2021)
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Journal Article
Antibody-mediated depletion of viral reservoirs is limited in SIV-infected macaques treated early with antiretroviral therapy
Swanstrom, Adrienne E, Immonen, Taina T, Oswald, Kelli, Pyle, Cathi, Thomas, James A, Bosche, William J, Silipino, Lorna, Hull, Michael, Newman, Laura, Coalter, Vicky, Wiles, Adam, Wiles, Rodney, Kiser, Jacob, Morcock, David R, Shoemaker, Rebecca, Fast, Randy, Breed, Matthew W, Kramer, Joshua, Donohue, Duncan, Malys, Tyler, Fennessey, Christine M, Trubey, Charles M, Deleage, Claire, Estes, Jacob D, Lifson, Jeffrey D, Keele, Brandon F, Del Prete, Gregory Q
Published in The Journal of clinical investigation (15.03.2021)
Published in The Journal of clinical investigation (15.03.2021)
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Journal Article
Interleukin-15 response signature predicts RhCMV/SIV vaccine efficacy
Barrenäs, Fredrik, Hansen, Scott G, Law, Lynn, Driscoll, Connor, Green, Richard R, Smith, Elise, Chang, Jean, Golez, Inah, Urion, Taryn, Peng, Xinxia, Whitmore, Leanne, Newhouse, Daniel, Hughes, Colette M, Morrow, David, Randall, Kurt T, Selseth, Andrea N, Ford, Julia C, Gilbride, Roxanne M, Randall, Bryan E, Ainslie, Emily, Oswald, Kelli, Shoemaker, Rebecca, Fast, Randy, Bosche, William J, Axthelm, Michael K, Fukazawa, Yoshinori, Pavlakis, George N, Felber, Barbara K, Fourati, Slim, Sekaly, Rafick-Pierre, Lifson, Jeffrey D, Komorowski, Jan, Kosmider, Ewelina, Shao, Danica, Song, Wenjun, Edlefsen, Paul T, Picker, Louis J, Gale, Michael
Published in PLoS pathogens (06.07.2021)
Published in PLoS pathogens (06.07.2021)
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TLR7 agonist administration to SIV-infected macaques receiving early initiated cART does not induce plasma viremia
Del Prete, Gregory Q, Alvord, W Gregory, Li, Yuan, Deleage, Claire, Nag, Mukta, Oswald, Kelli, Thomas, James A, Pyle, Cathi, Bosche, William J, Coalter, Vicky, Wiles, Adam, Wiles, Rodney, Berkemeier, Brian, Hull, Michael, Chipriano, Elizabeth, Silipino, Lorna, Fast, Randy, Kiser, Jacob, Kiser, Rebecca, Malys, Tyler, Kramer, Joshua, Breed, Matthew W, Trubey, Charles M, Estes, Jacob D, Barnes, Tiffany L, Hesselgesser, Joseph, Geleziunas, Romas, Lifson, Jeffrey D
Published in JCI insight (06.06.2019)
Published in JCI insight (06.06.2019)
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Human immunodeficiency virus type 1 nucleocapsid zn(2+) fingers are required for efficient reverse transcription, initial integration processes, and protection of newly synthesized viral DNA
Buckman, James S, Bosche, William J, Gorelick, Robert J
Published in Journal of virology (01.01.2003)
Published in Journal of virology (01.01.2003)
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Journal Article
Cytomegaloviral determinants of CD8 + T cell programming and RhCMV/SIV vaccine efficacy
Malouli, Daniel, Hansen, Scott G, Hancock, Meaghan H, Hughes, Colette M, Ford, Julia C, Gilbride, Roxanne M, Ventura, Abigail B, Morrow, David, Randall, Kurt T, Taher, Husam, Uebelhoer, Luke S, McArdle, Matthew R, Papen, Courtney R, Espinosa Trethewy, Renee, Oswald, Kelli, Shoemaker, Rebecca, Berkemeier, Brian, Bosche, William J, Hull, Michael, Greene, Justin M, Axthelm, Michael K, Shao, Jason, Edlefsen, Paul T, Grey, Finn, Nelson, Jay A, Lifson, Jeffrey D, Streblow, Daniel, Sacha, Jonah B, Früh, Klaus, Picker, Louis J
Published in Science immunology (25.03.2021)
Published in Science immunology (25.03.2021)
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Human Cellular Nucleic Acid-Binding Protein Zn2+ Fingers Support Replication of Human Immunodeficiency Virus Type 1 When They Are Substituted in the Nucleocapsid Protein
McGrath, Connor F, Buckman, James S, Gagliardi, Tracy D, Bosche, William J, Coren, Lori V, Gorelick, Robert J
Published in Journal of Virology (01.08.2003)
Published in Journal of Virology (01.08.2003)
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Journal Article
Myeloid cell tropism enables MHC-E-restricted CD8 + T cell priming and vaccine efficacy by the RhCMV/SIV vaccine
Hansen, Scott G, Hancock, Meaghan H, Malouli, Daniel, Marshall, Emily E, Hughes, Colette M, Randall, Kurt T, Morrow, David, Ford, Julia C, Gilbride, Roxanne M, Selseth, Andrea N, Trethewy, Renee Espinosa, Bishop, Lindsey M, Oswald, Kelli, Shoemaker, Rebecca, Berkemeier, Brian, Bosche, William J, Hull, Michael, Silipino, Lorna, Nekorchuk, Michael, Busman-Sahay, Kathleen, Estes, Jacob D, Axthelm, Michael K, Smedley, Jeremy, Shao, Danica, Edlefsen, Paul T, Lifson, Jeffrey D, Früh, Klaus, Nelson, Jay A, Picker, Louis J
Published in Science immunology (24.06.2022)
Published in Science immunology (24.06.2022)
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Human Immunodeficiency Virus Type 1 Nucleocapsid Zn2+ Fingers Are Required for Efficient Reverse Transcription, Initial Integration Processes, and Protection of Newly Synthesized Viral DNA
Buckman, James S., Bosche, William J., Gorelick, Robert J.
Published in Journal of Virology (01.01.2003)
Published in Journal of Virology (01.01.2003)
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Journal Article
Human immunodeficiency virus type 1 nucleocapsid zinc-finger mutations cause defects in reverse transcription and integration
Thomas, James A., Gagliardi, Tracy D., Alvord, W. Gregory, Lubomirski, Mariusz, Bosche, William J., Gorelick, Robert J.
Published in Virology (New York, N.Y.) (15.09.2006)
Published in Virology (New York, N.Y.) (15.09.2006)
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