Induced Pluripotent Stem Cell-Derived Megakaryocytes and Platelets for Disease Modeling and Future Clinical Applications
Borst, Sara, Sim, Xiuli, Poncz, Mortimer, French, Deborah L, Gadue, Paul
Published in Arteriosclerosis, thrombosis, and vascular biology (01.11.2017)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.11.2017)
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Restoring RUNX1 deficiency in RUNX1 familial platelet disorder by inhibiting its degradation
Krutein, Michelle C., Hart, Matthew R., Anderson, Donovan J., Jeffery, Jasmin, Kotini, Andriana G., Dai, Jin, Chien, Sylvia, DelPriore, Michaela, Borst, Sara, Maguire, Jean Ann, French, Deborah L., Gadue, Paul, Papapetrou, Eirini P., Keel, Siobán B., Becker, Pamela S., Horwitz, Marshall S.
Published in Blood advances (09.02.2021)
Published in Blood advances (09.02.2021)
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RUNX-1 haploinsufficiency causes a marked deficiency of megakaryocyte-biased hematopoietic progenitor cells
Estevez, Brian, Borst, Sara, Jarocha, Danuta, Sudunagunta, Varun, Gonzalez, Michael, Garifallou, James, Hakonarson, Hakon, Gao, Peng, Tan, Kai, Liu, Paul, Bagga, Sumedha, Holdreith, Nicholas, Tong, Wei, Speck, Nancy, French, Deborah L., Gadue, Paul, Poncz, Mortimer
Published in Blood (13.05.2021)
Published in Blood (13.05.2021)
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The Inherited Platelet Disorder of RUNX1 Haploinsufficiency (Familial Platelet Disorder with Associated Myeloid Malignancy (FPDMM)) Has a Marked Deficiency of Megakaryocyte-Biased Hematopoietic Progenitor Cells: Mechanistic Studies and Drug Correction
Estevez, Brian, Borst, Sara, Jarocha, Danuta Jadwiga, Sudunagunta, Varun, Gonzalez, Michael, Gao, Peng, Tan, Kai, French, Deborah L, Gadue, Paul, Poncz, Mortimer
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Journal Article
A Novel Approach for Generating Platelet-Delivered FVIII: Role of Transient LRP1 Expression during Megakaryopoiesis
Tkaczynski, John, Lyde, Randolph, Ahn, Hyunsook, Ayombil, Francis, Borst, Sara, Gadue, Paul, French, Deborah L, Sabatino, Denise, Camire, Rodney M., Poncz, Mortimer
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Journal Article
Study of inherited thrombocytopenia resulting from mutations in ETV6 or RUNX1 using a human pluripotent stem cell model
Borst, Sara, Nations, Catriana C., Klein, Joshua G., Pavani, Giulia, Maguire, Jean Ann, Camire, Rodney M., Drazer, Michael W., Godley, Lucy A., French, Deborah L., Poncz, Mortimer, Gadue, Paul
Published in Stem cell reports (08.06.2021)
Published in Stem cell reports (08.06.2021)
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Journal Article
RUNX1 haploinsufficiency causes a marked deficiency of megakaryocyte-biased hematopoietic progenitor cells: Mechanistic studies and drug correction
Estevez, Brian, Borst, Sara, Jarocha, Danuta, Sudunagunta, Varun, Gonzalez, Michael, Garifallou, James, Hakonarson, Hakon, Gao, Peng, Tan, Kai, Liu, Paul P, Bagga, Sumedha, Holdreith, Nicholas, Tong, Wei, Speck, Nancy, French, Deborah, Gadue, Paul, Mortimer Poncz
Published in bioRxiv (24.08.2020)
Published in bioRxiv (24.08.2020)
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