PEPCK Coordinates the Regulation of Central Carbon Metabolism to Promote Cancer Cell Growth
Montal, Emily D., Dewi, Ruby, Bhalla, Kavita, Ou, Lihui, Hwang, Bor Jang, Ropell, Ashley E., Gordon, Chris, Liu, Wan-Ju, DeBerardinis, Ralph J., Sudderth, Jessica, Twaddel, William, Boros, Laszlo G., Shroyer, Kenneth R., Duraisamy, Sekhar, Drapkin, Ronny, Powers, R. Scott, Rohde, Jason M., Boxer, Matthew B., Wong, Kwok-Kin, Girnun, Geoffrey D.
Published in Molecular cell (19.11.2015)
Published in Molecular cell (19.11.2015)
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Transcription factor NRF2 regulates miR-1 and miR-206 to drive tumorigenesis
Singh, Anju, Happel, Christine, Manna, Soumen K, Acquaah-Mensah, George, Carrerero, Julian, Kumar, Sarvesh, Nasipuri, Poonam, Krausz, Kristopher W, Wakabayashi, Nobunao, Dewi, Ruby, Boros, Laszlo G, Gonzalez, Frank J, Gabrielson, Edward, Wong, Kwok K, Girnun, Geoffrey, Biswal, Shyam
Published in The Journal of clinical investigation (01.07.2013)
Published in The Journal of clinical investigation (01.07.2013)
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Journal Article
An Inhibitor of GSK3B and HDACs Kills Pancreatic Cancer Cells and Slows Pancreatic Tumor Growth and Metastasis in Mice
Edderkaoui, Mouad, Chheda, Chintan, Soufi, Badr, Zayou, Fouzia, Hu, Robert W., Ramanujan, V. Krishnan, Pan, Xinlei, Boros, Laszlo G., Tajbakhsh, Jian, Madhav, Anisha, Bhowmick, Neil A., Wang, Qiang, Lewis, Michael, Tuli, Richard, Habtezion, Aida, Murali, Ramachandran, Pandol, Stephen J.
Published in Gastroenterology (New York, N.Y. 1943) (01.12.2018)
Published in Gastroenterology (New York, N.Y. 1943) (01.12.2018)
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Journal Article
A roadmap for interpreting (13)C metabolite labeling patterns from cells
Buescher, Joerg M, Antoniewicz, Maciek R, Boros, Laszlo G, Burgess, Shawn C, Brunengraber, Henri, Clish, Clary B, DeBerardinis, Ralph J, Feron, Olivier, Frezza, Christian, Ghesquiere, Bart, Gottlieb, Eyal, Hiller, Karsten, Jones, Russell G, Kamphorst, Jurre J, Kibbey, Richard G, Kimmelman, Alec C, Locasale, Jason W, Lunt, Sophia Y, Maddocks, Oliver D K, Malloy, Craig, Metallo, Christian M, Meuillet, Emmanuelle J, Munger, Joshua, Nöh, Katharina, Rabinowitz, Joshua D, Ralser, Markus, Sauer, Uwe, Stephanopoulos, Gregory, St-Pierre, Julie, Tennant, Daniel A, Wittmann, Christoph, Vander Heiden, Matthew G, Vazquez, Alexei, Vousden, Karen, Young, Jamey D, Zamboni, Nicola, Fendt, Sarah-Maria
Published in Current opinion in biotechnology (01.08.2015)
Published in Current opinion in biotechnology (01.08.2015)
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What to eat or what not to eat-that is still the question
Boros, László G, Collins, T Que, Somlyai, Gábor
Published in Neuro-oncology (Charlottesville, Va.) (01.04.2017)
Published in Neuro-oncology (Charlottesville, Va.) (01.04.2017)
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Metabolic reprogramming for producing energy and reducing power in fumarate hydratase null cells from hereditary leiomyomatosis renal cell carcinoma
Yang, Youfeng, Lane, Andrew N, Ricketts, Christopher J, Sourbier, Carole, Wei, Ming-Hui, Shuch, Brian, Pike, Lisa, Wu, Min, Rouault, Tracey A, Boros, Laszlo G, Fan, Teresa W-M, Linehan, W Marston
Published in PloS one (15.08.2013)
Published in PloS one (15.08.2013)
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Journal Article
Fructose Induces Transketolase Flux to Promote Pancreatic Cancer Growth
HAIBO LIU, DANSHAN HUANG, MCARTHUR, David L, BOROS, Laszlo G, NISSEN, Nicholas, HEANEY, Anthony P
Published in Cancer research (Chicago, Ill.) (01.08.2010)
Published in Cancer research (Chicago, Ill.) (01.08.2010)
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Summiting Mount Everest in deuterium depleting nutritional ketosis without supplemental oxygen
Boros, László G., Seneff, Stephanie, Lech, James C., Túri, Marianna, Répás, Zoltán
Published in Medical hypotheses (01.04.2024)
Published in Medical hypotheses (01.04.2024)
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Cancer-associated Isocitrate Dehydrogenase 1 (IDH1) R132H Mutation and d-2-Hydroxyglutarate Stimulate Glutamine Metabolism under Hypoxia
Reitman, Zachary J., Duncan, Christopher G., Poteet, Ethan, Winters, Ali, Yan, Liang-Jun, Gooden, David M., Spasojevic, Ivan, Boros, Laszlo G., Yang, Shao-Hua, Yan, Hai
Published in The Journal of biological chemistry (22.08.2014)
Published in The Journal of biological chemistry (22.08.2014)
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De novo lipogenesis represents a therapeutic target in mutant Kras non-small cell lung cancer
Singh, Anju, Ruiz, Christian, Bhalla, Kavita, Haley, John A, Li, Qing Kay, Acquaah-Mensah, George, Montal, Emily, Sudini, Kuladeep R, Skoulidis, Ferdinandos, Wistuba, Ignacio I, Papadimitrakopoulou, Vassiliki, Heymach, John V, Boros, Laszlo G, Gabrielson, Edward, Carretero, Julian, Wong, Kwok-Kin, Haley, John D, Biswal, Shyam, Girnun, Geoffrey D
Published in The FASEB journal (15.06.2018)
Published in The FASEB journal (15.06.2018)
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5′-AMP-activated Protein Kinase (AMPK) Supports the Growth of Aggressive Experimental Human Breast Cancer Tumors
Laderoute, Keith R., Calaoagan, Joy M., Chao, Wan-ru, Dinh, Dominc, Denko, Nicholas, Duellman, Sarah, Kalra, Jessica, Liu, Xiaohe, Papandreou, Ioanna, Sambucetti, Lidia, Boros, Laszlo G.
Published in The Journal of biological chemistry (15.08.2014)
Published in The Journal of biological chemistry (15.08.2014)
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AMPK activation through mitochondrial regulation results in increased substrate oxidation and improved metabolic parameters in models of diabetes
Jenkins, Yonchu, Sun, Tian-Qiang, Markovtsov, Vadim, Foretz, Marc, Li, Wei, Nguyen, Henry, Li, Yingwu, Pan, Alison, Uy, Gerald, Gross, Lisa, Baltgalvis, Kristen, Yung, Stephanie L, Gururaja, Tarikere, Kinoshita, Taisei, Owyang, Alexander, Smith, Ira J, McCaughey, Kelly, White, Kathy, Godinez, Guillermo, Alcantara, Raniel, Choy, Carmen, Ren, Hong, Basile, Rachel, Sweeny, David J, Xu, Xiang, Issakani, Sarkiz D, Carroll, David C, Goff, Dane A, Shaw, Simon J, Singh, Rajinder, Boros, Laszlo G, Laplante, Marc-André, Marcotte, Bruno, Kohen, Rita, Viollet, Benoit, Marette, André, Payan, Donald G, Kinsella, Todd M, Hitoshi, Yasumichi
Published in PloS one (05.12.2013)
Published in PloS one (05.12.2013)
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Journal Article
Iron regulates glucose homeostasis in liver and muscle via AMP-activated protein kinase in mice
Huang, Jingyu, Simcox, Judith, Mitchell, T Creighton, Jones, Deborah, Cox, James, Luo, Bai, Cooksey, Robert C, Boros, Laszlo G, McClain, Donald A
Published in The FASEB journal (01.07.2013)
Published in The FASEB journal (01.07.2013)
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Journal Article
Abnormalities in glucose uptake and metabolism in imatinib-resistant human BCR-ABL-positive cells
Kominsky, Douglas J, Klawitter, Jelena, Brown, Jaimi L, Boros, Laszlo G, Melo, Junia V, Eckhardt, S Gail, Serkova, Natalie J
Published in Clinical cancer research (15.05.2009)
Published in Clinical cancer research (15.05.2009)
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Journal Article
Fructose impairs glucose-induced hepatic triglyceride synthesis
Huang, Danshan, Dhawan, Tania, Young, Stephen, Yong, William H, Boros, Laszlo G, Heaney, Anthony P
Published in Lipids in health and disease (24.01.2011)
Published in Lipids in health and disease (24.01.2011)
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Journal Article
Survival Pathways of HIF-Deficient Tumour Cells: TCA Inhibition, Peroxisomal Fatty Acid Oxidation Activation and an AMPK-PGC-1α Hypoxia Sensor
Golinska, Monika A, Stubbs, Marion, Harris, Adrian L, Boros, Laszlo G, Basetti, Madhu, McIntyre, Dominick J O, Griffiths, John R
Published in Cells (Basel, Switzerland) (01.11.2022)
Published in Cells (Basel, Switzerland) (01.11.2022)
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Journal Article
Biological Reductionism versus Redundancy in a Degenerate World
Joyner, Michael J, Boros, Laszlo G, Fink, Gregory
Published in Perspectives in biology and medicine (2018)
Published in Perspectives in biology and medicine (2018)
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Dual modulation of both lipid oxidation and synthesis by peroxisome proliferator-activated receptor-γ coactivator-1α and -1β in cultured myotubes
Espinoza, Daniel O, Boros, Laszlo G, Crunkhorn, Sarah, Gami, Hiral, Patti, Mary-Elizabeth
Published in The FASEB journal (01.04.2010)
Published in The FASEB journal (01.04.2010)
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