Search Results - "Bornemeier, Dirk" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Discovery and Characterization of a Novel Inhibitor of Matrix Metalloprotease-13 That Reduces Cartilage Damage in Vivo without Joint Fibroplasia Side Effects

Discovery and Characterization of a Novel Inhibitor of Matrix Metalloprotease-13 That Reduces Cartilage Damage in Vivo without Joint Fibroplasia Side Effects

by Johnson, Adam R., Pavlovsky, Alexander G., Ortwine, Daniel F., Prior, Faith, Man, Chiu-Fai, Bornemeier, Dirk A., Banotai, Craig A., Mueller, W. Thomas, McConnell, Patrick, Yan, Chunhong, Baragi, Vijay, Lesch, Charles, Roark, W. Howard, Wilson, Michael, Datta, Kaushik, Guzman, Roberto, Han, Hyo-Kyung, Dyer, Richard D.
Published in The Journal of biological chemistry (21.09.2007)

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Journal Article

Synthesis, Structure−Activity Relationships, and in Vivo Evaluations of Substituted Di-tert-butylphenols as a Novel Class of Potent, Selective, and Orally Active Cyclooxygenase-2 Inhibitors. 2. 1,3,4- and 1,2,4-Thiadiazole Series

Synthesis, Structure−Activity Relationships, and in Vivo Evaluations of Substituted Di-tert-butylphenols as a Novel Class of Potent, Selective, and Orally Active Cyclooxygenase-2 Inhibitors. 2. 1,3,4- and 1,2,4-Thiadiazole Series

by Song, Yuntao, Connor, David T, Sercel, Anthony D, Sorenson, Roderick J, Doubleday, Robert, Unangst, Paul C, Roth, Bruce D, Beylin, Vlad G, Gilbertsen, Richard B, Chan, Kam, Schrier, Denis J, Guglietta, Antonio, Bornemeier, Dirk A, Dyer, Richard D
Published in Journal of medicinal chemistry (08.04.1999)

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Journal Article

Synthesis, Structure−Activity Relationships, and in Vivo Evaluations of Substituted Di-tert-butylphenols as a Novel Class of Potent, Selective, and Orally Active Cyclooxygenase-2 Inhibitors. 1. Thiazolone and Oxazolone Series

Synthesis, Structure−Activity Relationships, and in Vivo Evaluations of Substituted Di-tert-butylphenols as a Novel Class of Potent, Selective, and Orally Active Cyclooxygenase-2 Inhibitors. 1. Thiazolone and Oxazolone Series

by Song, Yuntao, Connor, David T, Doubleday, Robert, Sorenson, Roderick J, Sercel, Anthony D, Unangst, Paul C, Roth, Bruce D, Gilbertsen, Richard B, Chan, Kam, Schrier, Denis J, Guglietta, Antonio, Bornemeier, Dirk A, Dyer, Richard D
Published in Journal of medicinal chemistry (08.04.1999)

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1,3,4-Oxadiazole, 1,3,4-thiadiazole, and 1,2,4-triazole analogs of the fenamates: in vitro inhibition of cyclooxygenase and 5-lipoxygenase activities

1,3,4-Oxadiazole, 1,3,4-thiadiazole, and 1,2,4-triazole analogs of the fenamates: in vitro inhibition of cyclooxygenase and 5-lipoxygenase activities

by Boschelli, Diane H, Connor, David T, Bornemeier, Dirk A, Dyer, Richard D, Kennedy, John A, Kuipers, Paul J, Okonkwo, Godwin C, Schrier, Denis J, Wright, Clifford D
Published in Journal of medicinal chemistry (01.06.1993)

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Structure of a small‐molecule inhibitor complexed with GlmU from Haemophilus influenzae reveals an allosteric binding site

Structure of a small‐molecule inhibitor complexed with GlmU from Haemophilus influenzae reveals an allosteric binding site

by Mochalkin, Igor, Lightle, Sandra, Narasimhan, Lakshmi, Bornemeier, Dirk, Melnick, Michael, VanderRoest, Steven, McDowell, Laura
Published in Protein science (01.03.2008)

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Journal Article

Effect of Species Differences on Stromelysin-1 (MMP-3) Inhibitor Potency

Effect of Species Differences on Stromelysin-1 (MMP-3) Inhibitor Potency

by Johnson, Linda L., Bornemeier, Dirk A., Janowicz, Jeffrey A., Chen, Jing, Pavlovsky, Alexander G., Ortwine, Daniel F.
Published in The Journal of biological chemistry (27.08.1999)

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Journal Article

Identifying Promising Compounds in Drug Discovery: Genetic Algorithms and Some New Statistical Techniques

Identifying Promising Compounds in Drug Discovery: Genetic Algorithms and Some New Statistical Techniques

by Mandal, Abhyuday, Johnson, Kjell, Wu, C. F. Jeff, Bornemeier, Dirk
Published in Journal of chemical information and modeling (01.05.2007)

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Journal Article

Effect of species differences on stromelysin-1 (MMP-3) inhibitor potency. An explanation of inhibitor selectivity using homology modeling and chimeric proteins

Effect of species differences on stromelysin-1 (MMP-3) inhibitor potency. An explanation of inhibitor selectivity using homology modeling and chimeric proteins

by Johnson, L L, Bornemeier, D A, Janowicz, J A, Chen, J, Pavlovsky, A G, Ortwine, D F
Published in The Journal of biological chemistry (27.08.1999)

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Journal Article

Identifying Promising Compounds in Drug Discovery: Genetic Algorithms and Some New Statistical Techniques

Identifying Promising Compounds in Drug Discovery: Genetic Algorithms and Some New Statistical Techniques

by Mandal, Abhyuday, Johnson, Kjell, Wu, C. F. Jeff, Bornemeier, Dirk
Published in ChemInform (14.08.2007)

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Journal Article

Catechol based inhibitors of 15-lipoxygenase

Catechol based inhibitors of 15-lipoxygenase

by Tait, Bradley D., Dyer, Richard D., Auerbach, Bruce J., Bornemeier, Dirk, Guilds-Zamarka, Linda, Oxender, Maritza, Roth, Bruce D., Trivedi, Bharat K., Cornicelli, Joseph A.
Published in Bioorganic & medicinal chemistry letters (09.01.1996)

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Journal Article

Conversion of NSAIDS into balanced dual inhibitors of cyclooxygenase and 5-lipoxygenase

Conversion of NSAIDS into balanced dual inhibitors of cyclooxygenase and 5-lipoxygenase

by Boschelli, Diane H., Connor, David T., Hoefle, Milton, Bornemeier, Dirk A., Dyer, Richard D.
Published in Bioorganic & medicinal chemistry letters (1992)

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Journal Article

Hydroxylamine analogs of 2,6 di- t-butylphenols: Dual inhibitors of cyclooxygenase and 5-lipoxygenase or selective 5-lipoxygenase inhibitors

Hydroxylamine analogs of 2,6 di- t-butylphenols: Dual inhibitors of cyclooxygenase and 5-lipoxygenase or selective 5-lipoxygenase inhibitors

by Kramer, James B., Capiris, Thomas, Sircar, Jagadish C., Connor, David T., Bornemeier, Dirk A., Dyer, Richard D., Kuipers, Paul J., Kennedy, John A., Wright, Clifford D., Okonkwo, Godwin C.N., Lesch, Mark E., Schrier, Denis J., Boschelli, Diane H.
Published in Bioorganic & medicinal chemistry (01.04.1995)

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Journal Article

Purification of a mammalian 5-lipoxygenase from rat basophilic leukemia cells

Purification of a mammalian 5-lipoxygenase from rat basophilic leukemia cells

by Goetze, Andrew M., Fayer, Liz, Bouska, Jennifer, Bornemeier, Dirk, Carter, George W.
Published in Prostaglandins (01.05.1985)

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Journal Article

Cyclooxygenase and 5-lipoxygenase inhibitory activity of 2,6 di- t-butylphenols linked by a sulfur atom to 1,3,4-thiadiazoles and 1,3,4-oxadiazoles

Cyclooxygenase and 5-lipoxygenase inhibitory activity of 2,6 di- t-butylphenols linked by a sulfur atom to 1,3,4-thiadiazoles and 1,3,4-oxadiazoles

by Kramer, James B., Boschelli, Diane H., Connor, David T., Kostlan, Catherine R., Kuipers, Paul J., Kennedy, John A., Wright, Clifford D., Bornemeier, Dirk A., Dyer, Richard D.
Published in Bioorganic & medicinal chemistry letters (01.12.1993)

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Journal Article

Synthesis of reversed hydroxamic acids of indomethacin: dual inhibitors of cyclooxygenase and 5-lipoxygenase

Synthesis of reversed hydroxamic acids of indomethacin: dual inhibitors of cyclooxygenase and 5-lipoxygenase

by Kramer, James B., Boschelli, Diane H., Connor, David T., Kostlan, Catherine R., Flynn, Daniel L., Dyer, Richard D., Bornemeier, Dirk A., Kennedy, John A., Wright, Clifford D., Kuipers, Paul J.
Published in Bioorganic & medicinal chemistry letters (01.12.1992)

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Journal Article

OXADIAZOLE COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS

OXADIAZOLE COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS

by HOLSWORTH, DANIEL DALE, FORS, KRISTINA SEAN, BORNEMEIER, DIRK ALAN, JALAIE, MEHRAN, TAKE, YUKINORI, HAGEN, TIMOTHY JOSEPH, MOODY, THOMAS SHAW, CAI, CUIMAN, LEONARD, DANIELE MARIE
Year of Publication 02.05.2008

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