Myxoid smooth muscle neoplasia of the uterus: comprehensive analysis by next-generation sequencing and nucleic acid hybridization
Yoon, Ju-Yoon, Mariño-Enriquez, Adrian, Stickle, Natalie, de Borja, Richard J., Ismiil, Nadia, Djordjevic, Bojana, Virtanen, Carl, Ravat, Aastha, Nucci, Marisa R., Mirkovic, Jelena, Parra-Herran, Carlos
Published in Modern pathology (01.11.2019)
Published in Modern pathology (01.11.2019)
Get full text
Journal Article
Explosive mutation accumulation triggered by heterozygous human Pol ε proofreading-deficiency is driven by suppression of mismatch repair
Hodel, Karl P, de Borja, Richard, Henninger, Erin E, Campbell, Brittany B, Ungerleider, Nathan, Light, Nicholas, Wu, Tong, LeCompte, Kimberly G, Goksenin, A Yasemin, Bunnell, Bruce A, Tabori, Uri, Shlien, Adam, Pursell, Zachary F
Published in eLife (28.02.2018)
Published in eLife (28.02.2018)
Get full text
Journal Article
Immune Checkpoint Inhibition for Hypermutant Glioblastoma Multiforme Resulting From Germline Biallelic Mismatch Repair Deficiency
Bouffet, Eric, Larouche, Valérie, Campbell, Brittany B, Merico, Daniele, de Borja, Richard, Aronson, Melyssa, Durno, Carol, Krueger, Joerg, Cabric, Vanja, Ramaswamy, Vijay, Zhukova, Nataliya, Mason, Gary, Farah, Roula, Afzal, Samina, Yalon, Michal, Rechavi, Gideon, Magimairajan, Vanan, Walsh, Michael F, Constantini, Shlomi, Dvir, Rina, Elhasid, Ronit, Reddy, Alyssa, Osborn, Michael, Sullivan, Michael, Hansford, Jordan, Dodgshun, Andrew, Klauber-Demore, Nancy, Peterson, Lindsay, Patel, Sunil, Lindhorst, Scott, Atkinson, Jeffrey, Cohen, Zane, Laframboise, Rachel, Dirks, Peter, Taylor, Michael, Malkin, David, Albrecht, Steffen, Dudley, Roy W R, Jabado, Nada, Hawkins, Cynthia E, Shlien, Adam, Tabori, Uri
Published in Journal of clinical oncology (01.07.2016)
Published in Journal of clinical oncology (01.07.2016)
Get full text
Journal Article
Genomic hallmarks of localized, non-indolent prostate cancer
Fraser, Michael, Sabelnykova, Veronica Y., Yamaguchi, Takafumi N., Heisler, Lawrence E., Livingstone, Julie, Huang, Vincent, Shiah, Yu-Jia, Yousif, Fouad, Lin, Xihui, Masella, Andre P., Fox, Natalie S., Xie, Michael, Prokopec, Stephenie D., Berlin, Alejandro, Lalonde, Emilie, Ahmed, Musaddeque, Trudel, Dominique, Luo, Xuemei, Beck, Timothy A., Meng, Alice, Zhang, Junyan, D’Costa, Alister, Denroche, Robert E., Kong, Haiying, Espiritu, Shadrielle Melijah G., Chua, Melvin L. K., Wong, Ada, Chong, Taryne, Sam, Michelle, Johns, Jeremy, Timms, Lee, Buchner, Nicholas B., Orain, Michèle, Picard, Valérie, Hovington, Helène, Murison, Alexander, Kron, Ken, Harding, Nicholas J., P’ng, Christine, Houlahan, Kathleen E., Chu, Kenneth C., Lo, Bryan, Nguyen, Francis, Li, Constance H., Sun, Ren X., de Borja, Richard, Cooper, Christopher I., Hopkins, Julia F., Govind, Shaylan K., Fung, Clement, Waggott, Daryl, Green, Jeffrey, Haider, Syed, Chan-Seng-Yue, Michelle A., Jung, Esther, Wang, Zhiyuan, Bergeron, Alain, Dal Pra, Alan, Lacombe, Louis, Collins, Colin C., Sahinalp, Cenk, Lupien, Mathieu, Fleshner, Neil E., He, Housheng H., Fradet, Yves, Tetu, Bernard, van der Kwast, Theodorus, McPherson, John D., Bristow, Robert G., Boutros, Paul C.
Published in Nature (London) (19.01.2017)
Published in Nature (London) (19.01.2017)
Get full text
Journal Article
Robust global microRNA expression profiling using next-generation sequencing technologies
Tam, Shirley, de Borja, Richard, Tsao, Ming-Sound, McPherson, John D
Published in Laboratory investigation (01.03.2014)
Published in Laboratory investigation (01.03.2014)
Get full text
Journal Article
Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers
Shlien, Adam, Campbell, Brittany B, de Borja, Richard, Alexandrov, Ludmil B, Merico, Daniele, Wedge, David, Van Loo, Peter, Tarpey, Patrick S, Coupland, Paul, Behjati, Sam, Pollett, Aaron, Lipman, Tatiana, Heidari, Abolfazl, Deshmukh, Shriya, Avitzur, Na'ama, Meier, Bettina, Gerstung, Moritz, Hong, Ye, Merino, Diana M, Ramakrishna, Manasa, Remke, Marc, Arnold, Roland, Panigrahi, Gagan B, Thakkar, Neha P, Hodel, Karl P, Henninger, Erin E, Göksenin, A Yasemin, Bakry, Doua, Charames, George S, Druker, Harriet, Lerner-Ellis, Jordan, Mistry, Matthew, Dvir, Rina, Grant, Ronald, Elhasid, Ronit, Farah, Roula, Taylor, Glenn P, Nathan, Paul C, Alexander, Sarah, Ben-Shachar, Shay, Ling, Simon C, Gallinger, Steven, Constantini, Shlomi, Dirks, Peter, Huang, Annie, Scherer, Stephen W, Grundy, Richard G, Durno, Carol, Aronson, Melyssa, Gartner, Anton, Meyn, M Stephen, Taylor, Michael D, Pursell, Zachary F, Pearson, Christopher E, Malkin, David, Futreal, P Andrew, Stratton, Michael R, Bouffet, Eric, Hawkins, Cynthia, Campbell, Peter J, Tabori, Uri
Published in Nature genetics (01.03.2015)
Published in Nature genetics (01.03.2015)
Get full text
Journal Article
Spatial genomic heterogeneity within localized, multifocal prostate cancer
Boutros, Paul C, Fraser, Michael, Harding, Nicholas J, de Borja, Richard, Trudel, Dominique, Lalonde, Emilie, Meng, Alice, Hennings-Yeomans, Pablo H, McPherson, Andrew, Sabelnykova, Veronica Y, Zia, Amin, Fox, Natalie S, Livingstone, Julie, Shiah, Yu-Jia, Wang, Jianxin, Beck, Timothy A, Have, Cherry L, Chong, Taryne, Sam, Michelle, Johns, Jeremy, Timms, Lee, Buchner, Nicholas, Wong, Ada, Watson, John D, Simmons, Trent T, P'ng, Christine, Zafarana, Gaetano, Nguyen, Francis, Luo, Xuemei, Chu, Kenneth C, Prokopec, Stephenie D, Sykes, Jenna, Dal Pra, Alan, Berlin, Alejandro, Brown, Andrew, Chan-Seng-Yue, Michelle A, Yousif, Fouad, Denroche, Robert E, Chong, Lauren C, Chen, Gregory M, Jung, Esther, Fung, Clement, Starmans, Maud H W, Chen, Hanbo, Govind, Shaylan K, Hawley, James, D'Costa, Alister, Pintilie, Melania, Waggott, Daryl, Hach, Faraz, Lambin, Philippe, Muthuswamy, Lakshmi B, Cooper, Colin, Eeles, Rosalind, Neal, David, Tetu, Bernard, Sahinalp, Cenk, Stein, Lincoln D, Fleshner, Neil, Shah, Sohrab P, Collins, Colin C, Hudson, Thomas J, McPherson, John D, van der Kwast, Theodorus, Bristow, Robert G
Published in Nature genetics (01.07.2015)
Published in Nature genetics (01.07.2015)
Get full text
Journal Article
Rearrangement bursts generate canonical gene fusions in bone and soft tissue tumors
Anderson, Nathaniel D, de Borja, Richard, Young, Matthew D, Fuligni, Fabio, Rosic, Andrej, Roberts, Nicola D, Hajjar, Simon, Layeghifard, Mehdi, Novokmet, Ana, Kowalski, Paul E, Anaka, Matthew, Davidson, Scott, Zarrei, Mehdi, Id Said, Badr, Schreiner, L Christine, Marchand, Remi, Sitter, Joseph, Gokgoz, Nalan, Brunga, Ledia, Graham, Garrett T, Fullam, Anthony, Pillay, Nischalan, Toretsky, Jeffrey A, Yoshida, Akihiko, Shibata, Tatsuhiro, Metzler, Markus, Somers, Gino R, Scherer, Stephen W, Flanagan, Adrienne M, Campbell, Peter J, Schiffman, Joshua D, Shago, Mary, Alexandrov, Ludmil B, Wunder, Jay S, Andrulis, Irene L, Malkin, David, Behjati, Sam, Shlien, Adam
Published in Science (American Association for the Advancement of Science) (31.08.2018)
Published in Science (American Association for the Advancement of Science) (31.08.2018)
Get full text
Journal Article
Hotspot activating PRKD1 somatic mutations in polymorphous low-grade adenocarcinomas of the salivary glands
Weinreb, Ilan, Piscuoglio, Salvatore, Martelotto, Luciano G, Waggott, Daryl, Ng, Charlotte K Y, Perez-Ordonez, Bayardo, Harding, Nicholas J, Alfaro, Javier, Chu, Kenneth C, Viale, Agnes, Fusco, Nicola, da Cruz Paula, Arnaud, Marchio, Caterina, Sakr, Rita A, Lim, Raymond, Thompson, Lester D R, Chiosea, Simion I, Seethala, Raja R, Skalova, Alena, Stelow, Edward B, Fonseca, Isabel, Assaad, Adel, How, Christine, Wang, Jianxin, de Borja, Richard, Chan-Seng-Yue, Michelle, Howlett, Christopher J, Nichols, Anthony C, Wen, Y Hannah, Katabi, Nora, Buchner, Nicholas, Mullen, Laura, Kislinger, Thomas, Wouters, Bradly G, Liu, Fei-Fei, Norton, Larry, McPherson, John D, Rubin, Brian P, Clarke, Blaise A, Weigelt, Britta, Boutros, Paul C, Reis-Filho, Jorge S
Published in Nature genetics (01.11.2014)
Published in Nature genetics (01.11.2014)
Get full text
Journal Article
BPG: Seamless, automated and interactive visualization of scientific data
P'ng, Christine, Green, Jeffrey, Chong, Lauren C, Waggott, Daryl, Prokopec, Stephenie D, Shamsi, Mehrdad, Nguyen, Francis, Mak, Denise Y F, Lam, Felix, Albuquerque, Marco A, Wu, Ying, Jung, Esther H, Starmans, Maud H W, Chan-Seng-Yue, Michelle A, Yao, Cindy Q, Liang, Bianca, Lalonde, Emilie, Haider, Syed, Simone, Nicole A, Sendorek, Dorota, Chu, Kenneth C, Moon, Nathalie C, Fox, Natalie S, Grzadkowski, Michal R, Harding, Nicholas J, Fung, Clement, Murdoch, Amanda R, Houlahan, Kathleen E, Wang, Jianxin, Garcia, David R, de Borja, Richard, Sun, Ren X, Lin, Xihui, Chen, Gregory M, Lu, Aileen, Shiah, Yu-Jia, Zia, Amin, Kearns, Ryan, Boutros, Paul C
Published in BMC bioinformatics (21.01.2019)
Published in BMC bioinformatics (21.01.2019)
Get full text
Journal Article
Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis
Light, Nicholas, Layeghifard, Mehdi, Attery, Ayush, Subasri, Vallijah, Zatzman, Matthew, Anderson, Nathaniel D., Hatkar, Rupal, Blay, Sasha, Chen, David, Novokmet, Ana, Fuligni, Fabio, Tran, James, de Borja, Richard, Agarwal, Himanshi, Waldman, Larissa, Abegglen, Lisa M., Albertson, Daniel, Finlay, Jonathan L., Hansford, Jordan R., Behjati, Sam, Villani, Anita, Gerstung, Moritz, Alexandrov, Ludmil B., Somers, Gino R., Schiffman, Joshua D., Rotter, Varda, Malkin, David, Shlien, Adam
Published in Nature communications (05.01.2023)
Published in Nature communications (05.01.2023)
Get full text
Journal Article
Emergence of a mutation in the nucleocapsid gene of SARS-CoV-2 interferes with PCR detection in Canada
Isabel, Sandra, Abdulnoor, Mariana, Boissinot, Karel, Isabel, Marc R., de Borja, Richard, Zuzarte, Philip C., Sjaarda, Calvin P., R. Barker, Kevin, Sheth, Prameet M., Matukas, Larissa M., Gubbay, Jonathan B., McGeer, Allison J., Mubareka, Samira, Simpson, Jared T., Fattouh, Ramzi
Published in Scientific reports (27.06.2022)
Published in Scientific reports (27.06.2022)
Get full text
Journal Article
Author Correction: Emergence of a mutation in the nucleocapsid gene of SARS-CoV-2 interferes with PCR detection in Canada
Isabel, Sandra, Abdulnoor, Mariana, Boissinot, Karel, Isabel, Marc R., de Borja, Richard, Zuzarte, Philip C., Sjaarda, Calvin P., Barker, Kevin R., Sheth, Prameet M., Matukas, Larissa M., Gubbay, Jonathan B., McGeer, Allison J., Mubareka, Samira, Simpson, Jared T., Fattouh, Ramzi
Published in Scientific reports (19.08.2022)
Published in Scientific reports (19.08.2022)
Get full text
Journal Article
TMOD-10. REPLICATION REPAIR DEFICIENT MOUSE MODELS PROVIDE INSIGHT ON HYPERMUTANT BRAIN TUMOURS AND COMBINATIONAL IMMUNOTHERAPY
Galati, Melissa, Bridge, Taylor, Sudhaman, Sumedha, Elshaer, Dana, Ercan, Ayse, Joksimovic, Lazar, Gams, Miki, Hodel, Karl, Lipman, Tatiana, Siddiqui, Iram, Borja, Richard de, Forster, Victoria, Martin, Alberto, Bouffet, Eric, Shlien, Adam, Guidos, Cynthia, Pursell, Zachary, Hawkins, Cynthia, Tabori, Uri
Published in Neuro-oncology (Charlottesville, Va.) (23.04.2019)
Published in Neuro-oncology (Charlottesville, Va.) (23.04.2019)
Get full text
Journal Article
CanDIG: Federated network across Canada for multi-omic and health data discovery and analysis
Dursi, L. Jonathan, Bozoky, Zoltan, de Borja, Richard, Li, Haoyuan, Bujold, David, Lipski, Adam, Rashid, Shaikh Farhan, Sethi, Amanjeev, Memon, Neelam, Naidoo, Dashaylan, Coral-Sasso, Felipe, Wong, Matthew, Quirion, P-O, Lu, Zhibin, Agarwal, Samarth, Pavlov, Yuriy, Ponomarev, Andrew, Husic, Mia, Pace, Krista, Palmer, Samantha, Grover, Stephanie A., Hakgor, Sevan, Siu, Lillian L., Malkin, David, Virtanen, Carl, Pugh, Trevor J., Jacques, Pierre-Étienne, Joly, Yann, Jones, Steven J.M., Bourque, Guillaume, Brudno, Michael
Published in Cell genomics (10.11.2021)
Published in Cell genomics (10.11.2021)
Get full text
Journal Article
Detection of the novel SARS-CoV-2 European lineage B.1.177 in Ontario, Canada
Guthrie, Jennifer L., Teatero, Sarah, Zittermann, Sandra, Chen, Yao, Sullivan, Ashleigh, Rilkoff, Heather, Joshi, Esha, Sivaraman, Karthikeyan, de Borja, Richard, Sundaravadanam, Yogi, Laszloffy, Michael, Heisler, Lawrence, Allen, Vanessa G., Simpson, Jared T., Fittipaldi, Nahuel
Published in Journal of clinical virology plus (01.06.2021)
Published in Journal of clinical virology plus (01.06.2021)
Get full text
Journal Article
Comprehensive Analysis of Hypermutation in Human Cancer
Campbell, Brittany B., Light, Nicholas, Fabrizio, David, Zatzman, Matthew, Fuligni, Fabio, de Borja, Richard, Davidson, Scott, Edwards, Melissa, Elvin, Julia A., Hodel, Karl P., Zahurancik, Walter J., Suo, Zucai, Lipman, Tatiana, Wimmer, Katharina, Kratz, Christian P., Bowers, Daniel C., Laetsch, Theodore W., Dunn, Gavin P., Johanns, Tanner M., Grimmer, Matthew R., Smirnov, Ivan V., Larouche, Valérie, Samuel, David, Bronsema, Annika, Osborn, Michael, Stearns, Duncan, Raman, Pichai, Cole, Kristina A., Storm, Phillip B., Yalon, Michal, Opocher, Enrico, Mason, Gary, Thomas, Gregory A., Sabel, Magnus, George, Ben, Ziegler, David S., Lindhorst, Scott, Issai, Vanan Magimairajan, Constantini, Shlomi, Toledano, Helen, Elhasid, Ronit, Farah, Roula, Dvir, Rina, Dirks, Peter, Huang, Annie, Galati, Melissa A., Chung, Jiil, Ramaswamy, Vijay, Irwin, Meredith S., Aronson, Melyssa, Durno, Carol, Taylor, Michael D., Rechavi, Gideon, Maris, John M., Bouffet, Eric, Hawkins, Cynthia, Costello, Joseph F., Meyn, M. Stephen, Pursell, Zachary F., Malkin, David, Tabori, Uri, Shlien, Adam
Published in Cell (16.11.2017)
Published in Cell (16.11.2017)
Get full text
Journal Article
Diverse Oncogenic Fusions and Distinct Gene Expression Patterns Define the Genomic Landscape of Pediatric Papillary Thyroid Carcinoma
Stosic, Ana, Fuligni, Fabio, Anderson, Nathaniel D, Davidson, Scott, de Borja, Richard, Acker, Meryl, Forte, Vito, Campisi, Paolo, Propst, Evan J, Wolter, Nikolaus E, Chami, Rose, Mete, Ozgur, Malkin, David, Shlien, Adam, Wasserman, Jonathan D
Published in Cancer research (Chicago, Ill.) (15.11.2021)
Published in Cancer research (Chicago, Ill.) (15.11.2021)
Get full text
Journal Article
Coronavirus disease 2019 (COVID-19) outbreak on an in-patient medical unit associated with unrecognized exposures in common areas—Epidemiological and whole-genome sequencing investigation
Kain, Dylan C., Isabel, Sandra, Abdulnoor, Mariana, Boissinot, Karel, De Borja, Richard, Filkin, Amanda, Lam, Bernard, Li, Jason, Lungu, Ilinca, McCreight, Liz, McGeer, Allison, Mazzulli, Tony, Paterson, Aimee, Zuzarte, Philip, Vincelli, Felicia, Bergwerff, Cassandra, Fattouh, Ramzi, Simpson, Jared T., Johnstone, Jennie
Published in Infection control and hospital epidemiology (01.11.2023)
Published in Infection control and hospital epidemiology (01.11.2023)
Get full text
Journal Article