Pharmacological evaluation of novel Alzheimer's disease therapeutics: acetylcholinesterase inhibitors related to galanthamine
G M Bores, F P Huger, W Petko, A E Mutlib, F Camacho, D K Rush, D E Selk, V Wolf, R W Kosley, Jr, L Davis, H M Vargas
Published in The Journal of pharmacology and experimental therapeutics (01.05.1996)
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Published in The Journal of pharmacology and experimental therapeutics (01.05.1996)
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Amyloid β-peptides inhibit Na/K-ATPase: tissue slices versus primary cultures
Bores, G.M, Smith, C.P, Wirtz-Brugger, F, Giovanni, A
Published in Brain research bulletin (15.07.1998)
Published in Brain research bulletin (15.07.1998)
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Synthesis and Evaluation of 5-Amino-5,6,7,8-tetrahydroquinolinones as Potential Agents for the Treatment of Alzheimer's Disease
Fink, David M, Bores, Gina M, Effland, Richard C, Huger, Francis P, Kurys, Barbara E, Rush, Douglas K, Selk, David E
Published in Journal of medicinal chemistry (01.09.1995)
Published in Journal of medicinal chemistry (01.09.1995)
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9-Amino-1,2,3,4-tetrahydroacridin-1-ols. Synthesis and evaluation as potential Alzheimer's disease therapeutics
Shutske, Gregory M, Pierrat, Frank A, Kapples, Kevin J, Cornfeldt, Michael L, Szewczak, Mark R, Huger, Francis P, Bores, Gina M, Haroutunian, Vahram, Davis, Kenneth L
Published in Journal of medicinal chemistry (01.08.1989)
Published in Journal of medicinal chemistry (01.08.1989)
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(.+-.)-9-Amino-1,2,3,4-tetrahydroacridin-1-ol. A potential Alzheimer's disease therapeutic of low toxicity
Shutske, Gregory M, Pierrat, Frank A, Cornfeldt, Michael L, Szewczak, Mark R, Huger, Francis P, Bores, Gina M, Haroutunian, Vahram, Davis, Kenneth L
Published in Journal of medicinal chemistry (01.07.1988)
Published in Journal of medicinal chemistry (01.07.1988)
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Serotonergic activity of HP 184: does spontaneous release have a role?
Smith, C P, Woods-Kettelberger, A T, Corbett, R, Chesson, S M, Bores, G M, Petko, W W, Roehr, J E, Kongsamut, S
Published in Neurochemical research (01.05.1996)
Published in Neurochemical research (01.05.1996)
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AMINOPYRIDINE CARBAMIC ACID-ESTERS - SYNTHESIS AND POTENTIAL AS ACETYLCHOLINESTERASE INHIBITORS AND ACETYLCHOLINE RELEASERS
SHUTSKE, GM, TOMER, JD, KAPPLES, KJ, HRIB, NJ, JURCAK, JG, BORES, GM, HUGER, FP, PETKO, W, SMITH, CP
Published in Journal of pharmaceutical sciences (01.04.1992)
Published in Journal of pharmaceutical sciences (01.04.1992)
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Pharmacological activity and safety profile of P10358, a novel, orally active acetylcholinesterase inhibitor for Alzheimer's disease
Smith, C P, Bores, G M, Petko, W, Li, M, Selk, D E, Rush, D K, Camacho, F, Winslow, J T, Fishkin, R, Cunningham, D M, Brooks, K M, Roehr, J, Hartman, H B, Davis, L, Vargas, H M
Published in The Journal of pharmacology and experimental therapeutics (01.02.1997)
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Published in The Journal of pharmacology and experimental therapeutics (01.02.1997)
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Synthesis and preliminary structure-activity relationships of 1-[(3-fluoro-4-pyridinyl)amino]-3-methyl-1H-indol-5-yl methyl carbamate (P10358), a novel acetylcholinesterase inhibitor
Martin, Lawrence L., Davis, Larry, Klein, Joseph T., Nemoto, Peter, Olsen, Gordon E., Bores, Gina M., Camacho, Fernando, Petko, Wayne W., Rush, Douglas K., Selk, David, Smith, Craig P., Vargas, Hugo M., Winslow, James T., Effland, Richard C., Fink, David M.
Published in Bioorganic & medicinal chemistry letters (21.01.1997)
Published in Bioorganic & medicinal chemistry letters (21.01.1997)
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Besipirdine (HP 749) reduces schedule-induced polydipsia in rats
Woods-Kettleberger, A.T., Smith, C.P., Corbett, R., Szewczak, M.R., Roehr, J.E., Bores, G.M., Klein, J.T., Kongsamut, S.
Published in Brain research bulletin (1996)
Published in Brain research bulletin (1996)
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Amyloid beta -peptides inhibit Na super(+)/K super(+)-ATPase: Tissue slices versus primary cultures
Bores, G M, Smith, C P, Wirtz-Brugger, F, Giovanni, A
Published in Brain research bulletin (01.07.1998)
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Published in Brain research bulletin (01.07.1998)
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Imino 1,2,3,4-tetrahydrocyclopent[b]indole carbamates as dual inhibitors of acetylcholinesterase and monoamine oxidase
Fink, David M., Palermo, M.G., Bores, Gina M., Huger, Francis P., Kurys, Barbara E., Merriman, Michael C., Olsen, Gordon E., Petko, Wayne, O'Malley, Gerard J.
Published in Bioorganic & medicinal chemistry letters (19.03.1996)
Published in Bioorganic & medicinal chemistry letters (19.03.1996)
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Anti‐Obsessional and Antidepressant Profile of Besipirdine
Smith, C. P., Woods‐Kettelberger, A. T., Corbett, R., Porsolt, R. D., Roehr, J. E., Bores, G. M., Giovanni, A., Szewczak, M. R., Rush, D. K., Martin, L. L., Klein, J. T., Turk, D. J., DiLeo, E. M., Effland, R. C., Huger, F. P., Kongsamut, S.
Published in CNS drug reviews (01.03.1997)
Published in CNS drug reviews (01.03.1997)
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