Disparate Degrees of Hypervariable Loop Flexibility Control T-Cell Receptor Cross-Reactivity, Specificity, and Binding Mechanism
Scott, Daniel R., Borbulevych, Oleg Y., Piepenbrink, Kurt H., Corcelli, Steven A., Baker, Brian M.
Published in Journal of molecular biology (02.12.2011)
Published in Journal of molecular biology (02.12.2011)
Get full text
Journal Article
MovableType Software for Fast Free Energy-Based Virtual Screening: Protocol Development, Deployment, Validation, and Assessment
Zheng, Zheng, Borbulevych, Oleg Y, Liu, Hao, Deng, Jianpeng, Martin, Roger I, Westerhoff, Lance M
Published in Journal of chemical information and modeling (23.11.2020)
Published in Journal of chemical information and modeling (23.11.2020)
Get full text
Journal Article
T Cell Receptor Cross-reactivity Directed by Antigen-Dependent Tuning of Peptide-MHC Molecular Flexibility
Borbulevych, Oleg Y., Piepenbrink, Kurt H., Gloor, Brian E., Scott, Daniel R., Sommese, Ruth F., Cole, David K., Sewell, Andrew K., Baker, Brian M.
Published in Immunity (Cambridge, Mass.) (18.12.2009)
Published in Immunity (Cambridge, Mass.) (18.12.2009)
Get full text
Journal Article
Accurate macromolecular crystallographic refinement: incorporation of the linear scaling, semiempirical quantum-mechanics program DivCon into the PHENIX refinement package
Borbulevych, Oleg Y., Plumley, Joshua A., Martin, Roger I., Merz Jr, Kenneth M., Westerhoff, Lance M.
Published in Acta crystallographica. Section D, Biological crystallography. (01.05.2014)
Published in Acta crystallographica. Section D, Biological crystallography. (01.05.2014)
Get full text
Journal Article
Loss of T cell antigen recognition arising from changes in peptide and major histocompatibility complex protein flexibility: implications for vaccine design
Insaidoo, Francis K, Borbulevych, Oleg Y, Hossain, Moushumi, Santhanagopolan, Sujatha M, Baxter, Tiffany K, Baker, Brian M
Published in The Journal of biological chemistry (18.11.2011)
Published in The Journal of biological chemistry (18.11.2011)
Get full text
Journal Article
Probing Dimerization and Structural Flexibility of Mammalian Lipoxygenases by Small-Angle X-ray Scattering
Shang, Weifeng, Ivanov, Igor, Svergun, Dmitri I., Borbulevych, Oleg Y., Aleem, Ansari M., Stehling, Sabine, Jankun, Jerzy, Kühn, Hartmut, Skrzypczak-Jankun, Ewa
Published in Journal of molecular biology (17.06.2011)
Published in Journal of molecular biology (17.06.2011)
Get full text
Journal Article
Fluorine substitutions in an antigenic peptide selectively modulate T-cell receptor binding in a minimally perturbing manner
Piepenbrink, Kurt H, Borbulevych, Oleg Y, Sommese, Ruth F, Clemens, John, Armstrong, Kathryn M, Desmond, Clare, Do, Priscilla, Baker, Brian M
Published in Biochemical journal (01.11.2009)
Published in Biochemical journal (01.11.2009)
Get more information
Journal Article
Structures of MART-126/27-35 Peptide/HLA-A2 complexes reveal a remarkable disconnect between antigen structural homology and T cell recognition
Borbulevych, Oleg Y, Insaidoo, Francis K, Baxter, Tiffany K, Powell, Jr, Daniel J, Johnson, Laura A, Restifo, Nicholas P, Baker, Brian M
Published in Journal of molecular biology (05.10.2007)
Published in Journal of molecular biology (05.10.2007)
Get full text
Journal Article
Lipoxygenase interactions with natural flavonoid, quercetin, reveal a complex with protocatechuic acid in its X-ray structure at 2.1 Å resolution
Borbulevych, Oleg Y., Jankun, Jerzy, Selman, Steven H., Skrzypczak-Jankun, Ewa
Published in Proteins, structure, function, and bioinformatics (01.01.2004)
Published in Proteins, structure, function, and bioinformatics (01.01.2004)
Get full text
Journal Article
Increased Immunogenicity of an Anchor-Modified Tumor-Associated Antigen Is Due to the Enhanced Stability of the Peptide/MHC Complex: Implications for Vaccine Design
Borbulevych, Oleg Y, Baxter, Tiffany K, Yu, Zhiya, Restifo, Nicholas P, Baker, Brian M
Published in The Journal of immunology (1950) (15.04.2005)
Published in The Journal of immunology (1950) (15.04.2005)
Get full text
Journal Article
Increased Peptide Contacts Govern High Affinity Binding of a Modified TCR Whilst Maintaining a Native pMHC Docking Mode
Cole, David K, Sami, Malkit, Scott, Daniel R, Rizkallah, Pierre J, Borbulevych, Oleg Y, Todorov, Penio T, Moysey, Ruth K, Jakobsen, Bent K, Boulter, Jonathan M, Baker, Brian M, Yi Li
Published in Frontiers in immunology (01.01.2013)
Published in Frontiers in immunology (01.01.2013)
Get full text
Journal Article
T Cell Receptor Recognition via Cooperative Conformational Plasticity
Gagnon, Susan J., Borbulevych, Oleg Y., Davis-Harrison, Rebecca L., Turner, Richard V., Damirjian, Marale, Wojnarowicz, Alison, Biddison, William E., Baker, Brian M.
Published in Journal of molecular biology (13.10.2006)
Published in Journal of molecular biology (13.10.2006)
Get full text
Journal Article
Unraveling a Hotspot for TCR Recognition on HLA-A2: Evidence Against the Existence of Peptide-independent TCR Binding Determinants
Gagnon, Susan J., Borbulevych, Oleg Y., Davis-Harrison, Rebecca L., Baxter, Tiffany K., Clemens, John R., Armstrong, Kathryn M., Turner, Richard V., Damirjian, Marale, Biddison, William E., Baker, Brian M.
Published in Journal of molecular biology (28.10.2005)
Published in Journal of molecular biology (28.10.2005)
Get full text
Journal Article
Soybean lipoxygenase-3 in complex with 4-nitrocatechol
Skrzypczak-Jankun, Ewa, Borbulevych, Oleg Y., Jankun, Jerzy
Published in Acta crystallographica. Section D, Biological crystallography. (01.03.2004)
Published in Acta crystallographica. Section D, Biological crystallography. (01.03.2004)
Get full text
Journal Article
RS-MT Dock : movable-type ligand docking method using X-ray/cryo-EM experimental density and integrated QM/MM real-space refinement for drug design
Borbulevych, Oleg Y., Westerhoff, Lance M.
Published in Acta crystallographica. Section A, Foundations and advances (07.07.2023)
Published in Acta crystallographica. Section A, Foundations and advances (07.07.2023)
Get full text
Journal Article