The expression and function of microRNAs in chondrogenesis and osteoarthritis
Swingler, Tracey E., Wheeler, Guy, Carmont, Virginia, Elliott, Hannah R., Barter, Matthew J., Abu-Elmagd, Muhammad, Donell, Simon T., Boot-Handford, Raymond P., Hajihosseini, Mohammad K., Münsterberg, Andrea, Dalmay, Tamas, Young, David A., Clark, Ian M.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.06.2012)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.06.2012)
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Journal Article
The Circadian Clock in Murine Chondrocytes Regulates Genes Controlling Key Aspects of Cartilage Homeostasis
Gossan, Nicole, Zeef, Leo, Hensman, James, Hughes, Alun, Bateman, John F., Rowley, Lynn, Little, Christopher B., Piggins, Hugh D., Rattray, Magnus, Boot‐Handford, Raymond P., Meng, Qing‐Jun
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.09.2013)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.09.2013)
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Journal Article
CRELD2 Is a Novel LRP1 Chaperone That Regulates Noncanonical WNT Signaling in Skeletal Development
Dennis, Ella P, Edwards, Sarah M, Jackson, Robert M, Hartley, Claire L, Tsompani, Dimitra, Capulli, Mattia, Teti, Anna, Boot‐Handford, Raymond P, Young, David A, Piróg, Katarzyna A, Briggs, Michael D
Published in Journal of bone and mineral research (01.08.2020)
Published in Journal of bone and mineral research (01.08.2020)
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Journal Article
Increased classical endoplasmic reticulum stress is sufficient to reduce chondrocyte proliferation rate in the growth plate and decrease bone growth
Kung, Louise H W, Rajpar, M Helen, Preziosi, Richard, Briggs, Michael D, Boot-Handford, Raymond P
Published in PloS one (18.02.2015)
Published in PloS one (18.02.2015)
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Journal Article
Targeted induction of endoplasmic reticulum stress induces cartilage pathology
Rajpar, M Helen, McDermott, Ben, Kung, Louise, Eardley, Rachel, Knowles, Lynette, Heeran, Mel, Thornton, David J, Wilson, Richard, Bateman, John F, Poulsom, Richard, Arvan, Peter, Kadler, Karl E, Briggs, Michael D, Boot-Handford, Raymond P
Published in PLoS genetics (01.10.2009)
Published in PLoS genetics (01.10.2009)
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Journal Article
Cartilage endoplasmic reticulum stress may influence the onset but not the progression of experimental osteoarthritis
Kung, Louise H W, Mullan, Lorna, Soul, Jamie, Wang, Ping, Mori, Kazutoshi, Bateman, John F, Briggs, Michael D, Boot-Handford, Raymond P
Published in Arthritis research & therapy (11.09.2019)
Published in Arthritis research & therapy (11.09.2019)
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Journal Article
Increased intracellular proteolysis reduces disease severity in an ER stress-associated dwarfism
Mullan, Lorna A, Mularczyk, Ewa J, Kung, Louise H, Forouhan, Mitra, Wragg, Jordan Ma, Goodacre, Royston, Bateman, John F, Swanton, Eileithyia, Briggs, Michael D, Boot-Handford, Raymond P
Published in The Journal of clinical investigation (01.10.2017)
Published in The Journal of clinical investigation (01.10.2017)
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Journal Article
Armet/Manf and Creld2 are components of a specialized ER stress response provoked by inappropriate formation of disulphide bonds: implications for genetic skeletal diseases
Hartley, Claire L, Edwards, Sarah, Mullan, Lorna, Bell, Peter A, Fresquet, Maryline, Boot-Handford, Raymond P, Briggs, Michael D
Published in Human molecular genetics (20.12.2013)
Published in Human molecular genetics (20.12.2013)
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Journal Article
XBP1 signalling is essential for alleviating mutant protein aggregation in ER-stress related skeletal disease
Piróg, Katarzyna A, Dennis, Ella P, Hartley, Claire L, Jackson, Robert M, Soul, Jamie, Schwartz, Jean-Marc, Bateman, John F, Boot-Handford, Raymond P, Briggs, Michael D
Published in PLoS genetics (01.07.2019)
Published in PLoS genetics (01.07.2019)
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Journal Article
XBP1-Independent UPR Pathways Suppress C/EBP-β Mediated Chondrocyte Differentiation in ER-Stress Related Skeletal Disease
Cameron, Trevor L, Bell, Katrina M, Gresshoff, Irma L, Sampurno, Lisa, Mullan, Lorna, Ermann, Joerg, Glimcher, Laurie H, Boot-Handford, Raymond P, Bateman, John F
Published in PLoS genetics (01.09.2015)
Published in PLoS genetics (01.09.2015)
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Journal Article
Bub1 Maintains Centromeric Cohesion by Activation of the Spindle Checkpoint
Perera, David, Tilston, Valerie, Hopwood, Jane A., Barchi, Marco, Boot-Handford, Raymond P., Taylor, Stephen S.
Published in Developmental cell (01.10.2007)
Published in Developmental cell (01.10.2007)
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Journal Article
Abnormal chondrocyte apoptosis in the cartilage growth plate is influenced by genetic background and deletion of CHOP in a targeted mouse model of pseudoachondroplasia
Piróg, Katarzyna A, Irman, Andreja, Young, Siobhan, Halai, Poonam, Bell, Peter A, Boot-Handford, Raymond P, Briggs, Michael D
Published in PloS one (18.02.2014)
Published in PloS one (18.02.2014)
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Journal Article
Collagen XXVII organises the pericellular matrix in the growth plate
Plumb, Darren A, Ferrara, Laila, Torbica, Tanja, Knowles, Lynnette, Mironov, Jr, Aleksandr, Kadler, Karl E, Briggs, Michael D, Boot-Handford, Raymond P
Published in PloS one (19.12.2011)
Published in PloS one (19.12.2011)
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Journal Article
Col2a1 lineage tracing reveals that the meniscus of the knee joint has a complex cellular origin
Hyde, Gareth, Boot‐Handford, Raymond P., Wallis, Gillian A.
Published in Journal of anatomy (01.11.2008)
Published in Journal of anatomy (01.11.2008)
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Journal Article
Transcriptional profiling of chondrodysplasia growth plate cartilage reveals adaptive ER-stress networks that allow survival but disrupt hypertrophy
Cameron, Trevor L, Bell, Katrina M, Tatarczuch, Liliana, Mackie, Eleanor J, Rajpar, M Helen, McDermott, Ben T, Boot-Handford, Raymond P, Bateman, John F
Published in PloS one (15.09.2011)
Published in PloS one (15.09.2011)
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Journal Article
A novel form of chondrocyte stress is triggered by a COMP mutation causing pseudoachondroplasia
Suleman, Farhana, Gualeni, Benedetta, Gregson, Hannah J., Leighton, Matthew P., Piróg, Katarzyna A., Edwards, Sarah, Holden, Paul, Boot-Handford, Raymond P., Briggs, Michael D.
Published in Human mutation (01.01.2012)
Published in Human mutation (01.01.2012)
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