A computationally designed chimeric antigen receptor provides a small-molecule safety switch for T-cell therapy
Giordano-Attianese, Greta, Gainza, Pablo, Gray-Gaillard, Elise, Cribioli, Elisabetta, Shui, Sailan, Kim, Seonghoon, Kwak, Mi-Jeong, Vollers, Sabrina, Corria Osorio, Angel De Jesus, Reichenbach, Patrick, Bonet, Jaume, Oh, Byung-Ha, Irving, Melita, Coukos, George, Correia, Bruno E.
Published in Nature biotechnology (01.04.2020)
Published in Nature biotechnology (01.04.2020)
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Bottom-up de novo design of functional proteins with complex structural features
Yang, Che, Sesterhenn, Fabian, Bonet, Jaume, van Aalen, Eva A., Scheller, Leo, Abriata, Luciano A., Cramer, Johannes T., Wen, Xiaolin, Rosset, Stéphane, Georgeon, Sandrine, Jardetzky, Theodore, Krey, Thomas, Fussenegger, Martin, Merkx, Maarten, Correia, Bruno E.
Published in Nature chemical biology (01.04.2021)
Published in Nature chemical biology (01.04.2021)
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RosettaSurf-A surface-centric computational design approach
Scheck, Andreas, Rosset, Stéphane, Defferrard, Michaël, Loukas, Andreas, Bonet, Jaume, Vandergheynst, Pierre, Correia, Bruno E
Published in PLoS computational biology (16.03.2022)
Published in PLoS computational biology (16.03.2022)
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ADP-ribose–derived nuclear ATP synthesis by NUDIX5 is required for chromatin remodeling
Wright, Roni H. G., Lioutas, Antonios, Le Dily, Francois, Soronellas, Daniel, Pohl, Andy, Bonet, Jaume, Nacht, A. S., Samino, Sara, Font-Mateu, Jofre, Vicent, Guillermo P., Wierer, Michael, Trabado, Miriam A., Schelhorn, Constanze, Carolis, Carlo, Macias, Maria J., Yanes, Oscar, Oliva, Baldo, Beato, Miguel
Published in Science (American Association for the Advancement of Science) (03.06.2016)
Published in Science (American Association for the Advancement of Science) (03.06.2016)
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Preclinical development of a humanized chimeric antigen receptor against B cell maturation antigen for multiple myeloma
Perez-Amill, Lorena, Suñe, Guillermo, Antoñana-Vildosola, Asier, Castella, Maria, Najjar, Amer, Bonet, Jaume, Fernández-Fuentes, Narcis, Inogés, Susana, López, Ascensión, Bueno, Clara, Juan, Manel, Urbano-Ispizua, Álvaro, Martín-Antonio, Beatriz
Published in Haematologica (Roma) (01.01.2021)
Published in Haematologica (Roma) (01.01.2021)
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CDK2-dependent activation of PARP-1 is required for hormonal gene regulation in breast cancer cells
Wright, Roni H G, Castellano, Giancarlo, Bonet, Jaume, Le Dily, Francois, Font-Mateu, Jofre, Ballaré, Cecilia, Nacht, A Silvina, Soronellas, Daniel, Oliva, Baldo, Beato, Miguel
Published in Genes & development (01.09.2012)
Published in Genes & development (01.09.2012)
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Rosetta FunFolDes - A general framework for the computational design of functional proteins
Bonet, Jaume, Wehrle, Sarah, Schriever, Karen, Yang, Che, Billet, Anne, Sesterhenn, Fabian, Scheck, Andreas, Sverrisson, Freyr, Veselkova, Barbora, Vollers, Sabrina, Lourman, Roxanne, Villard, Mélanie, Rosset, Stéphane, Krey, Thomas, Correia, Bruno E
Published in PLoS computational biology (01.11.2018)
Published in PLoS computational biology (01.11.2018)
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SPServer: split-statistical potentials for the analysis of protein structures and protein-protein interactions
Aguirre-Plans, Joaquim, Meseguer, Alberto, Molina-Fernandez, Ruben, Marín-López, Manuel Alejandro, Jumde, Gaurav, Casanova, Kevin, Bonet, Jaume, Fornes, Oriol, Fernandez-Fuentes, Narcis, Oliva, Baldo
Published in BMC bioinformatics (06.01.2021)
Published in BMC bioinformatics (06.01.2021)
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Boosting subdominant neutralizing antibody responses with a computationally designed epitope-focused immunogen
Sesterhenn, Fabian, Galloux, Marie, Vollers, Sabrina S, Csepregi, Lucia, Yang, Che, Descamps, Delphyne, Bonet, Jaume, Friedensohn, Simon, Gainza, Pablo, Corthésy, Patricia, Chen, Man, Rosset, Stéphane, Rameix-Welti, Marie-Anne, Éléouët, Jean-François, Reddy, Sai T, Graham, Barney S, Riffault, Sabine, Correia, Bruno E
Published in PLoS biology (21.02.2019)
Published in PLoS biology (21.02.2019)
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ATTACK, a novel bispecific T cell-recruiting antibody with trivalent EGFR binding and monovalent CD3 binding for cancer immunotherapy
Harwood, Seandean Lykke, Alvarez-Cienfuegos, Ana, Nuñez-Prado, Natalia, Compte, Marta, Hernández-Pérez, Sara, Merino, Nekane, Bonet, Jaume, Navarro, Rocio, Van Bergen en Henegouwen, Paul M. P., Lykkemark, Simon, Mikkelsen, Kasper, Mølgaard, Kasper, Jabs, Frederic, Sanz, Laura, Blanco, Francisco J., Roda-Navarro, Pedro, Alvarez-Vallina, Luis
Published in Oncoimmunology (02.01.2018)
Published in Oncoimmunology (02.01.2018)
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Author Correction: A computationally designed chimeric antigen receptor provides a small-molecule safety switch for T-cell therapy
Giordano-Attianese, Greta, Gainza, Pablo, Gray-Gaillard, Elise, Cribioli, Elisabetta, Shui, Sailan, Kim, Seonghoon, Kwak, Mi-Jeong, Vollers, Sabrina, Corria Osorio, Angel De Jesus, Reichenbach, Patrick, Bonet, Jaume, Oh, Byung-Ha, Irving, Melita, Coukos, George, Correia, Bruno E.
Published in Nature biotechnology (01.04.2020)
Published in Nature biotechnology (01.04.2020)
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A PD-L1/EGFR bispecific antibody combines immune checkpoint blockade and direct anti-cancer action for an enhanced anti-tumor response
Rubio-Pérez, Laura, Lázaro-Gorines, Rodrigo, Harwood, Seandean L., Compte, Marta, Navarro, Rocío, Tapia-Galisteo, Antonio, Bonet, Jaume, Blanco, Belén, Lykkemark, Simon, Ramírez-Fernández, Ángel, Ferreras-Gutiérrez, Mariola, Domínguez-Alonso, Carmen, Díez-Alonso, Laura, Segura-Tudela, Alejandro, Hangiu, Oana, Erce-Llamazares, Ainhoa, Blanco, Francisco J., Santos, Cruz, Rodríguez-Peralto, José L., Sanz, Laura, Álvarez-Vallina, Luis
Published in Oncoimmunology (31.12.2023)
Published in Oncoimmunology (31.12.2023)
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Structure-based learning to predict and model protein-DNA interactions and transcription-factor co-operativity in cis -regulatory elements
Oriol, Fornes, Alberto, Meseguer, Joachim, Aguirre-Plans, Patrick, Gohl, M, Bota Patricia, Ruben, Molina-Fernández, Jaume, Bonet, Altair, Chinchilla-Hernandez, Ferran, Pegenaute, Oriol, Gallego, Narcis, Fernandez-Fuentes, Baldo, Oliva
Published in NAR genomics and bioinformatics (12.06.2024)
Published in NAR genomics and bioinformatics (12.06.2024)
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On the Use of Knowledge-Based Potentials for the Evaluation of Models of Protein–Protein, Protein–DNA, and Protein–RNA Interactions
Fornes, Oriol, Garcia-Garcia, Javier, Bonet, Jaume, Oliva, Baldo
Published in Advances in Protein Chemistry and Structural Biology (2014)
Published in Advances in Protein Chemistry and Structural Biology (2014)
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Book Chapter
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Human Albumin Impairs Amyloid β-peptide Fibrillation Through its C-terminus: From docking Modeling to Protection Against Neurotoxicity in Alzheimer's disease
Picón-Pagès, Pol, Bonet, Jaume, García-García, Javier, Garcia-Buendia, Joan, Gutierrez, Daniela, Valle, Javier, Gómez-Casuso, Carmen E.S., Sidelkivska, Valeriya, Alvarez, Alejandra, Perálvarez-Marín, Alex, Suades, Albert, Fernàndez-Busquets, Xavier, Andreu, David, Vicente, Rubén, Oliva, Baldomero, Muñoz, Francisco J.
Published in Computational and structural biotechnology journal (01.01.2019)
Published in Computational and structural biotechnology journal (01.01.2019)
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In vivo tumor targeting and imaging with engineered trivalent antibody fragments containing collagen-derived sequences
Cuesta, Angel M, Sánchez-Martín, David, Sanz, Laura, Bonet, Jaume, Compte, Marta, Kremer, Leonor, Blanco, Francisco J, Oliva, Baldomero, Alvarez-Vallina, Luis
Published in PloS one (29.04.2009)
Published in PloS one (29.04.2009)
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Amyloid-β Peptide Nitrotyrosination Stabilizes Oligomers and Enhances NMDAR-Mediated Toxicity
Guivernau, Biuse, Bonet, Jaume, Valls-Comamala, Victòria, Bosch-Morató, Mònica, Godoy, Juan A, Inestrosa, Nibaldo C, Perálvarez-Marín, Alex, Fernández-Busquets, Xavier, Andreu, David, Oliva, Baldomero, Muñoz, Francisco J
Published in The Journal of neuroscience (16.11.2016)
Published in The Journal of neuroscience (16.11.2016)
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Characterization of protein hubs by inferring interacting motifs from protein interactions
Aragues, Ramon, Sali, Andrej, Bonet, Jaume, Marti-Renom, Marc A, Oliva, Baldo
Published in PLoS computational biology (01.09.2007)
Published in PLoS computational biology (01.09.2007)
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