Simlukafusp alfa (FAP-IL2v) immunocytokine is a versatile combination partner for cancer immunotherapy
Waldhauer, Inja, Gonzalez-Nicolini, Valeria, Freimoser-Grundschober, Anne, Nayak, Tapan K, Fahrni, Linda, Hosse, Ralf J, Gerrits, Danny, Geven, Edwin J W, Sam, Johannes, Lang, Sabine, Bommer, Esther, Steinhart, Virginie, Husar, Elisabeth, Colombetti, Sara, Van Puijenbroek, Erwin, Neubauer, Markus, Cline, J Mark, Garg, Pradeep K, Dugan, Gregory, Cavallo, Federica, Acuna, Gonzalo, Charo, Jehad, Teichgräber, Volker, Evers, Stefan, Boerman, Otto C, Bacac, Marina, Moessner, Ekkehard, Umaña, Pablo, Klein, Christian
Published in mAbs (01.01.2021)
Published in mAbs (01.01.2021)
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Journal Article
Combination of T-Cell Bispecific Antibodies With PD-L1 Checkpoint Inhibition Elicits Superior Anti-Tumor Activity
Sam, Johannes, Colombetti, Sara, Fauti, Tanja, Roller, Andreas, Biehl, Marlene, Fahrni, Linda, Nicolini, Valeria, Perro, Mario, Nayak, Tapan, Bommer, Esther, Schoenle, Anne, Karagianni, Maria, Le Clech, Marine, Steinhoff, Nathalie, Klein, Christian, Umaña, Pablo, Bacac, Marina
Published in Frontiers in oncology (30.11.2020)
Published in Frontiers in oncology (30.11.2020)
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Journal Article
Corrigendum: Combination of T-Cell Bispecific Antibodies With PD-L1 Checkpoint Inhibition Elicits Superior Anti-Tumor Activity
Sam, Johannes, Colombetti, Sara, Fauti, Tanja, Roller, Andreas, Biehl, Marlene, Fahrni, Linda, Nicolini, Valeria, Perro, Mario, Nayak, Tapan, Bommer, Esther, Schoenle, Anne, Karagianni, Maria, Le Clech, Marine, Steinhoff, Nathalie, Klein, Christian, Umaña, Pablo, Bacac, Marina
Published in Frontiers in oncology (03.02.2021)
Published in Frontiers in oncology (03.02.2021)
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Journal Article
PD-1-cis IL-2R agonism yields better effectors from stem-like CD8+ T cells
Codarri Deak, Laura, Nicolini, Valeria, Hashimoto, Masao, Karagianni, Maria, Schwalie, Petra C., Lauener, Laura, Varypataki, Eleni Maria, Richard, Marine, Bommer, Esther, Sam, Johannes, Joller, Stefanie, Perro, Mario, Cremasco, Floriana, Kunz, Leo, Yanguez, Emilio, Hüsser, Tamara, Schlenker, Ramona, Mariani, Marisa, Tosevski, Vinko, Herter, Sylvia, Bacac, Marina, Waldhauer, Inja, Colombetti, Sara, Gueripel, Xavier, Wullschleger, Stephan, Tichet, Melanie, Hanahan, Douglas, Kissick, Haydn T., Leclair, Stephane, Freimoser-Grundschober, Anne, Seeber, Stefan, Teichgräber, Volker, Ahmed, Rafi, Klein, Christian, Umaña, Pablo
Published in Nature (London) (06.10.2022)
Published in Nature (London) (06.10.2022)
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Journal Article
RG6076 (CD19-4-1BBL): CD19-Targeted 4-1BB Ligand Combination with Glofitamab As an Off-the-Shelf, Enhanced T-Cell Redirection Therapy for B-Cell Malignancies
Herter, Sylvia, Sam, Johannes, Ferrara Koller, Claudia, Diggelmann, Sarah, Bommer, Esther, Schönle, Anne, Claus, Christina, Bacac, Marina, Klein, Christian, Umana, Pablo
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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Journal Article
CD19-CD28: an affinity-optimized CD28 agonist for combination with glofitamab (CD20-TCB) as off-the-shelf immunotherapy
Sam, Johannes, Hofer, Thomas, Kuettel, Christine, Claus, Christina, Thom, Jenny, Herter, Sylvia, Georges, Guy, Korfi, Koorosh, Lechmann, Martin, Eigenmann, Miro Julian, Marbach, Daniel, Jamois, Candice, Lechner, Katharina, Krishnan, Sreenath M., Gaillard, Brenda, Marinho, Joana, Kronenberg, Sven, Kunz, Leo, Wilson, Sabine, Briner, Stefanie, Gebhardt, Samuel, Varol, Ahmet, Appelt, Birte, Nicolini, Valeria, Speziale, Dario, Bez, Miriam, Bommer, Esther, Eckmann, Jan, Hage, Carina, Limani, Florian, Jenni, Silvia, Schoenle, Anne, Le Clech, Marine, Vallier, Jean-Baptiste Pierre, Colombetti, Sara, Bacac, Marina, Gasser, Stephan, Klein, Christian, Umaña, Pablo
Published in Blood (23.05.2024)
Published in Blood (23.05.2024)
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Journal Article
RG6333 (CD19-CD28), a CD19-Targeted Affinity-Optimized CD28 Bispecific Antibody, Enhances and Prolongs the Anti-Tumor Activity of Glofitamab (CD20-TCB) in Preclinical Models
Sam, Johannes, Hofer, Thomas, Kuettel, Christine, Claus, Christina, Herter, Sylvia, Georges, Guy, Thom, Jenny Tosca, Kunz, Leo, Gebhardt, Samuel, Limani, Florian, Briner, Stefanie, Jenni, Silvia, Schönle, Anne, Le Clech, Marine, Varol, Ahmet, Bommer, Esther, Appelt, Birte, Colombetti, Sara, Gasser, Stephan, Bacac, Marina, Klein, Christian, Umana, Pablo
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Abstract LB-389: Combination of TYRP1-TCB, a novel T cell bispecific antibody for the treatment of melanoma, with immunomodulatory agents
Nicolini, Valeria G., Waldhauer, Inja, Freimoser-Grundschober, Anne, Richard, Marine, Fahrni, Linda, Bommer, Esther, Claus, Christina, Sam, Johannes, Colombetti, Sara, Sutmuller, Roger, Levesque, Mitchell P., Irmisch, Anja, Bleul, Conrad, Campbell, Neil, Bacac, Marina, Moessner, Ekkehard, Klein, Christian, Umana, Pablo
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Abstract 1552: A novel PD1-IL2v immunocytokine for preferential cis -activation of IL-2R signaling on PD-1 expressing T cell subsets strongly potentiates anti-tumor T cell activity of PD-1 checkpoint inhibition and IL-2R-beta-gamma agonism
Klein, Christian, Codarri-Deak, Laura, Nicolini, Valeria, Seeber, Stefan, Lauener, Laura, Richard, Marine, Bommer, Esther, Karagianni, Maria, Sam, Johannes, Schlenker, Ramona, Mariani, Marisa, Schwalie, Petra Petra, Herter, Sylvia, Bacac, Marina, Waldhauer, Inja, Freimoser-Grundschober, Anne, Teichgraeber, Volker, Umana, Pablo
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Premedication and Chemotherapy Agents do not Impair Imgatuzumab (GA201)-Mediated Antibody-Dependent Cellular Cytotoxicity and Combination Therapies Enhance Efficacy
Gonzalez-Nicolini, Valeria, Herter, Sylvia, Lang, Sabine, Waldhauer, Inja, Bacac, Marina, Roemmele, Michaela, Bommer, Esther, Freytag, Olivier, van Puijenbroek, Erwin, Umaña, Pablo, Gerdes, Christian A
Published in Clinical cancer research (15.05.2016)
Published in Clinical cancer research (15.05.2016)
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Journal Article
Simlukafusp alfa (FAP-IL2v) immunocytokine is a versatile combination partner for cancer immunotherapy
Waldhauer, Inja, Gonzalez-Nicolini, Valeria, Freimoser-Grundschober, Anne, Nayak, Tapan K, Fahrni, Linda, Hosse, Ralf J., Gerrits, Danny, Geven, Edwin J. W., Sam, Johannes, Lang, Sabine, Bommer, Esther, Steinhart, Virginie, Husar, Elisabeth, Colombetti, Sara, Van Puijenbroek, Erwin, Neubauer, Markus, Cline, J. Mark, Garg, Pradeep K., Dugan, Gregory, Cavallo, Federica, Acuna, Gonzalo, Charo, Jehad, Teichgräber, Volker, Evers, Stefan, Boerman, Otto C., Bacac, Marina, Moessner, Ekkehard, Umaña, Pablo, Klein, Christian
Published in mAbs (01.01.2021)
Published in mAbs (01.01.2021)
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