Preclinical pharmacology of sugammadex
Bom, Anton, MD, PhD, Hope, Frank, BSc, Rutherford, Samantha, PhD, Thomson, Karen, BSc
Published in Journal of critical care (01.03.2009)
Published in Journal of critical care (01.03.2009)
Get full text
Journal Article
Cyclodextrin-Derived Host Molecules as Reversal Agents for the Neuromuscular Blocker Rocuronium Bromide: Synthesis and Structure−Activity Relationships
Adam, Julia M, Bennett, D. Jonathan, Bom, Anton, Clark, John K, Feilden, Helen, Hutchinson, Edward J, Palin, Ronald, Prosser, Alan, Rees, David C, Rosair, Georgina M, Stevenson, Donald, Tarver, Gary J, Zhang, Ming-Qiang
Published in Journal of medicinal chemistry (25.04.2002)
Published in Journal of medicinal chemistry (25.04.2002)
Get full text
Journal Article
Reversal of rocuronium-induced neuromuscular block by sugammadex is independent of renal perfusion in anesthetized cats
Staals, Lonneke M., de Boer, Hans D., van Egmond, Jan, Hope, Frank, van de Pol, Francien, Bom, Anton H., Driessen, Jacques J., Booij, Leo H. D. J.
Published in Journal of anesthesia (01.04.2011)
Published in Journal of anesthesia (01.04.2011)
Get full text
Journal Article
Sugammadex reverses neuromuscular block induced by 3-desacetyl-vecuronium, an active metabolite of vecuronium, in the anaesthetised rhesus monkey
Staals, Lonneke M, van Egmond, Jan, Driessen, Jacques J, de Boer, Hans D, van de Pol, Francien, Bom, Anton H, Booij, Leo Hdj
Published in European journal of anaesthesiology (01.04.2011)
Published in European journal of anaesthesiology (01.04.2011)
Get more information
Journal Article
Reversal of Neuromusclar Blockade and Simultaneous Increase in Plasma Rocuronium Concentration after the Intravenous Infusion of the Novel Reversal Agent Org 25970
Epemolu, Ola, Bom, Anton, Hope, Frank, Mason, Rona
Published in Anesthesiology (Philadelphia) (01.09.2003)
Published in Anesthesiology (Philadelphia) (01.09.2003)
Get full text
Journal Article
Reversal of neuromuscular blockade and simultaneous increase in plasma Rocuronium concentration after the intravenous infusion of the novel reversal agent Org 25969
EPEMOLU, Ola, BOM, Anton, HOPE, Frank, MASON, Rona
Published in Anesthesiology (Philadelphia) (01.09.2003)
Published in Anesthesiology (Philadelphia) (01.09.2003)
Get full text
Journal Article
A Novel Concept of Reversing Neuromuscular Block: Chemical Encapsulation of Rocuronium Bromide by a Cyclodextrin-Based Synthetic Host
Bom, Anton, Bradley, Mark, Cameron, Ken, Clark, John K., van Egmond, Jan, Feilden, Helen, MacLean, Elizabeth J., Muir, Alan W., Palin, Ronald, Rees, David C., Zhang, Ming-Qiang
Published in Angewandte Chemie International Edition (18.01.2002)
Published in Angewandte Chemie International Edition (18.01.2002)
Get full text
Journal Article
A novel concept of reversing neuromuscular block: chemical encapsulation of rocuronium bromide by a cyclodextrin-based synthetic host
Bom, Anton, Bradley, Mark, Cameron, Ken, Clark, John K, Van Egmond, Jan, Feilden, Helen, MacLean, Elizabeth J, Muir, Alan W, Palin, Ronald, Rees, David C, Zhang, Ming-Qiang
Published in Angewandte Chemie International Edition (18.01.2002)
Get full text
Published in Angewandte Chemie International Edition (18.01.2002)
Journal Article
A Novel Concept of Reversing Neuromuscular Block: Chemical Encapsulation of Rocuronium Bromide by a Cyclodextrin-Based Synthetic Host
Bom, Anton, Bradley, Mark, Cameron, Ken, Clark, John K., van Egmond, Jan, Feilden, Helen, MacLean, Elizabeth J., Muir, Alan W., Palin, Ronald, Rees, David C., Zhang, Ming-Qiang
Published in Angewandte Chemie (18.01.2002)
Published in Angewandte Chemie (18.01.2002)
Get full text
Journal Article
Selective relaxant binding agents for reversal of neuromuscular blockade
Bom, Anton, Epemolu, Ola, Hope, Frank, Rutherford, Samantha, Thomson, Karen
Published in Current opinion in pharmacology (01.06.2007)
Published in Current opinion in pharmacology (01.06.2007)
Get full text
Journal Article
Synthesis and evaluation of N-3 substituted phenoxypropyl piperidine benzimidazol-2-one analogues as NOP receptor agonists with analgesic and sedative properties
Palin, Ronald, Bom, Anton, Clark, John K., Evans, Louise, Feilden, Helen, Houghton, Andrea K., Jones, Philip S., Montgomery, Brian, Weston, Mark A., Wishart, Grant
Published in Bioorganic & medicinal chemistry (15.02.2007)
Published in Bioorganic & medicinal chemistry (15.02.2007)
Get full text
Journal Article
Effects of 5-hydroxytryptamine on capillary and arteriovenous anastomotic blood flow in the human hand and forearm and in the pig hind leg
Blauw, G, Bom, A H, van Brummelen, P, Camps, J, Arndt, J W, Verdouw, P D, Chang, P C, van Zwieten, P A, Saxena, P R
Published in Journal of cardiovascular pharmacology (01.02.1991)
Published in Journal of cardiovascular pharmacology (01.02.1991)
Get more information
Journal Article
2- O-Substituted Cyclodextrins as Reversal Agents for the Neuromuscular Blocker Rocuronium Bromide
Tarver, Gary J, Grove, Simon J.A, Buchanan, Kirsteen, Bom, Anton, Cooke, Andrew, Rutherford, Samantha J, Zhang, Ming-Qiang
Published in Bioorganic & medicinal chemistry (01.06.2002)
Published in Bioorganic & medicinal chemistry (01.06.2002)
Get full text
Journal Article
Parallel solid-phase synthesis of zatebradine analogues as potential If channel blockers
BOM, Anton, BOOTH, Susan, BRUIN, John, CLARK, John, MILLER, Susan, WATHEY, Bernard
Published in Bioorganic & medicinal chemistry letters (03.09.2001)
Published in Bioorganic & medicinal chemistry letters (03.09.2001)
Get full text
Journal Article
Parallel solid-Phase synthesis of zatebradine analogues as potential I f channel blockers
Bom, Anton, Booth, Susan, Bruin, John, Clark, John, Miller, Susan, Wathey, Bernard
Published in Bioorganic & medicinal chemistry letters (03.09.2001)
Published in Bioorganic & medicinal chemistry letters (03.09.2001)
Get full text
Journal Article
A Novel Concept of Reversing Neuromuscular Block: Chemical Encapsulation of Rocuronium Bromide by a Cyclodextrin-Based Synthetic Host The discovery of Org 25969 is the result of teamwork with contributions from a number of scientists both inside Organon and outside the company. We would like in particular to acknowledge the following scientists for their invaluable contributions: E. Hutchinson, D. Stevenson, R. Roy, and J. Pick for scaling-up the synthesis; F. Hope, S. Miller, and R. Mason for v
Bom, Anton, Bradley, Mark, Cameron, Ken, Clark, John K., van Egmond, Jan, Feilden, Helen, MacLean, Elizabeth J., Muir, Alan W., Palin, Ronald, Rees, David C., Zhang, Ming-Qiang
Published in Angewandte Chemie International Edition (18.01.2002)
Published in Angewandte Chemie International Edition (18.01.2002)
Get full text
Journal Article