Comprehensive fitness maps of Hsp90 show widespread environmental dependence
Flynn, Julia M, Rossouw, Ammeret, Cote-Hammarlof, Pamela, Fragata, Inês, Mavor, David, Hollins, 3rd, Carl, Bank, Claudia, Bolon, Daniel Na
Published in eLife (04.03.2020)
Published in eLife (04.03.2020)
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Comprehensive fitness landscape of SARS-CoV-2 Mpro reveals insights into viral resistance mechanisms
Flynn, Julia M, Samant, Neha, Schneider-Nachum, Gily, Barkan, David T, Yilmaz, Nese Kurt, Schiffer, Celia A, Moquin, Stephanie A, Dovala, Dustin, Bolon, Daniel NA
Published in eLife (20.06.2022)
Published in eLife (20.06.2022)
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A synthetic biology approach to probing nucleosome symmetry
Ichikawa, Yuichi, Connelly, Caitlin F, Appleboim, Alon, Miller, Thomas Cr, Jacobi, Hadas, Abshiru, Nebiyu A, Chou, Hsin-Jung, Chen, Yuanyuan, Sharma, Upasna, Zheng, Yupeng, Thomas, Paul M, Chen, Hsuiyi V, Bajaj, Vineeta, Müller, Christoph W, Kelleher, Neil L, Friedman, Nir, Bolon, Daniel Na, Rando, Oliver J, Kaufman, Paul D
Published in eLife (12.09.2017)
Published in eLife (12.09.2017)
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A systematic survey of an intragenic epistatic landscape
Bank, Claudia, Hietpas, Ryan T, Jensen, Jeffrey D, Bolon, Daniel N A
Published in Molecular biology and evolution (01.01.2015)
Published in Molecular biology and evolution (01.01.2015)
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Evolutionary mechanisms studied through protein fitness landscapes
Canale, Aneth S, Cote-Hammarlof, Pamela A, Flynn, Julia M, Bolon, Daniel NA
Published in Current opinion in structural biology (01.02.2018)
Published in Current opinion in structural biology (01.02.2018)
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An experimental evaluation of drug-induced mutational meltdown as an antiviral treatment strategy
Bank, Claudia, Renzette, Nicholas, Liu, Ping, Matuszewski, Sebastian, Shim, Hyunjin, Foll, Matthieu, Bolon, Daniel N. A., Zeldovich, Konstantin B., Kowalik, Timothy F., Finberg, Robert W., Wang, Jennifer P., Jensen, Jeffrey D.
Published in Evolution (01.11.2016)
Published in Evolution (01.11.2016)
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A Balance between Inhibitor Binding and Substrate Processing Confers Influenza Drug Resistance
Jiang, Li, Liu, Ping, Bank, Claudia, Renzette, Nicholas, Prachanronarong, Kristina, Yilmaz, Lutfu S., Caffrey, Daniel R., Zeldovich, Konstantin B., Schiffer, Celia A., Kowalik, Timothy F., Jensen, Jeffrey D., Finberg, Robert W., Wang, Jennifer P., Bolon, Daniel N.A.
Published in Journal of molecular biology (13.02.2016)
Published in Journal of molecular biology (13.02.2016)
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Latent Effects of Hsp90 Mutants Revealed at Reduced Expression Levels: e1003600
Jiang, Li, Mishra, Parul, Hietpas, Ryan T, Zeldovich, Konstantin B, Bolon, Daniel NA
Published in PLoS genetics (01.06.2013)
Published in PLoS genetics (01.06.2013)
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Systematic analyses of the resistance potential of drugs targeting SARS-CoV-2 main protease
Flynn, Julia M, Huang, Qiu Yu M, Zvornicanin, Sarah N, Schneider-Nachum, Gily, Shaqra, Ala M, Yilmaz, Nese Kurt, Moquin, Stephanie A, Dovala, Dustin, Schiffer, Celia A, Daniel Na Bolon
Published in bioRxiv (02.03.2023)
Published in bioRxiv (02.03.2023)
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Comprehensive fitness landscape of SARS-CoV-2 Mpro reveals insights into viral resistance mechanisms
Flynn, Julia M, Samant, Neha, Schneider-Nachum, Gily, Barkan, David T, Yilmaz, Nese Kurt, Schiffer, Celia A, Moquin, Stephanie A, Dovala, Dustin, Daniel Na Bolon
Published in bioRxiv (30.01.2022)
Published in bioRxiv (30.01.2022)
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Defining the Substrate Envelope of SARS-CoV-2 Main Protease to Predict and Avoid Drug Resistance
Shaqra, Ala M, Zvornicanin, Sarah, Qiu Yu Huang, Lockbaum, Gordon J, Knapp, Mark, Tandeske, Laura, Barkan, David T, Flynn, Julia, Daniel Na Bolon, Moquin, Stephanie, Dovala, Dustin, Yilmaz, Neşe Kurt, Schiffer, Celia A
Published in bioRxiv (27.01.2022)
Published in bioRxiv (27.01.2022)
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A systematic survey of an intragenic epistatic landscape
Bank, Claudia, Hietpas, Ryan T, Jensen, Jeffrey D, Daniel Na Bolon
Published in bioRxiv (23.10.2014)
Published in bioRxiv (23.10.2014)
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Paper
An experimental evaluation of drug-induced mutational meltdown as an antiviral treatment strategy
Bank, Claudia, Renzette, Nicholas, Liu, Ping, Matuszewski, Sebastian, Shim, Hyunjin, Foll, Matthieu, Daniel Na Bolon, Zeldovich, Konstantin B, Kowalik, Timothy F, Finberg, Robert W, Wang, Jennifer P, Jensen, Jeffrey D
Published in bioRxiv (02.06.2016)
Published in bioRxiv (02.06.2016)
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