PBPK models for the prediction of in vivo performance of oral dosage forms
Kostewicz, Edmund S., Aarons, Leon, Bergstrand, Martin, Bolger, Michael B., Galetin, Aleksandra, Hatley, Oliver, Jamei, Masoud, Lloyd, Richard, Pepin, Xavier, Rostami-Hodjegan, Amin, Sjögren, Erik, Tannergren, Christer, Turner, David B., Wagner, Christian, Weitschies, Werner, Dressman, Jennifer
Published in European journal of pharmaceutical sciences (16.06.2014)
Published in European journal of pharmaceutical sciences (16.06.2014)
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Journal Article
The Prediction of the Relative Importance of CYP3A/P-glycoprotein to the Nonlinear Intestinal Absorption of Drugs by Advanced Compartmental Absorption and Transit Model
Takano, Junichi, Maeda, Kazuya, Bolger, Michael B, Sugiyama, Yuichi
Published in Drug metabolism and disposition (01.11.2016)
Published in Drug metabolism and disposition (01.11.2016)
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Journal Article
Predicting the impact of physiological and biochemical processes on oral drug bioavailability
Agoram, Balaji, Woltosz, Walter S., Bolger, Michael B.
Published in Advanced drug delivery reviews (01.10.2001)
Published in Advanced drug delivery reviews (01.10.2001)
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Journal Article
Conference Proceeding
Cystic fibrosis transmembrane conductance regulator activation by roflumilast contributes to therapeutic benefit in chronic bronchitis
Lambert, James A, Raju, S Vamsee, Tang, Li Ping, McNicholas, Carmel M, Li, Yao, Courville, Clifford A, Farris, Roopan F, Coricor, George E, Smoot, Lisa H, Mazur, Marina M, Dransfield, Mark T, Bolger, Graeme B, Rowe, Steven M
Published in American journal of respiratory cell and molecular biology (01.03.2014)
Published in American journal of respiratory cell and molecular biology (01.03.2014)
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Journal Article
The RACK1 scaffold protein: a dynamic cog in cell response mechanisms
McCahill, Angela, Warwicker, Jim, Bolger, Graeme B, Houslay, Miles D, Yarwood, Stephen J
Published in Molecular pharmacology (01.12.2002)
Published in Molecular pharmacology (01.12.2002)
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Journal Article
In Silico Modeling for the Nonlinear Absorption Kinetics of UK-343,664: A P-gp and CYP3A4 Substrate
Abuasal, Bilal S, Bolger, Michael B, Walker, Don K, Kaddoumi, Amal
Published in Molecular pharmaceutics (05.03.2012)
Published in Molecular pharmaceutics (05.03.2012)
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Journal Article
Isoform-Selective Susceptibility of DISC1/Phosphodiesterase-4 Complexes to Dissociation by Elevated Intracellular cAMP Levels
Murdoch, Hannah, Mackie, Shaun, Collins, Daniel M, Hill, Elaine V, Bolger, Graeme B, Klussmann, Enno, Porteous, David J, Millar, J. Kirsty, Houslay, Miles D
Published in The Journal of neuroscience (29.08.2007)
Published in The Journal of neuroscience (29.08.2007)
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Journal Article
PBPK Modeling as a Tool for Predicting and Understanding Intestinal Metabolism of Uridine 5′-Diphospho-glucuronosyltransferase Substrates
Reddy, Micaela B., Bolger, Michael B., Fraczkiewicz, Grace, Del Frari, Laurence, Luo, Laibin, Lukacova, Viera, Mitra, Amitava, Macwan, Joyce S., Mullin, Jim M., Parrott, Neil, Heikkinen, Aki T.
Published in Pharmaceutics (24.08.2021)
Published in Pharmaceutics (24.08.2021)
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Journal Article
Reduced protein expression of the phosphodiesterases PDE4A4 and PDE4A8 in AIP mutation positive somatotroph adenomas
Bizzi, Mariana Ferreira, Pinheiro, Sergio Veloso Brant, Bolger, Graeme B., Schweizer, Junia Ribeiro de Oliveira Longo, Giannetti, Alexandre V., Dang, Mary N., Ribeiro-Oliveira, Antonio, Korbonits, Márta
Published in Molecular and cellular endocrinology (15.11.2018)
Published in Molecular and cellular endocrinology (15.11.2018)
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Journal Article