Landmarks of human embryonic development inscribed in somatic mutations
Bizzotto, Sara, Dou, Yanmei, Ganz, Javier, Doan, Ryan N, Kwon, Minseok, Bohrson, Craig L, Kim, Sonia N, Bae, Taejeong, Abyzov, Alexej, Park, Peter J, Walsh, Christopher A
Published in Science (American Association for the Advancement of Science) (19.03.2021)
Published in Science (American Association for the Advancement of Science) (19.03.2021)
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Aging and neurodegeneration are associated with increased mutations in single human neurons
Lodato, Michael A, Rodin, Rachel E, Bohrson, Craig L, Coulter, Michael E, Barton, Alison R, Kwon, Minseok, Sherman, Maxwell A, Vitzthum, Carl M, Luquette, Lovelace J, Yandava, Chandri N, Yang, Pengwei, Chittenden, Thomas W, Hatem, Nicole E, Ryu, Steven C, Woodworth, Mollie B, Park, Peter J, Walsh, Christopher A
Published in Science (American Association for the Advancement of Science) (02.02.2018)
Published in Science (American Association for the Advancement of Science) (02.02.2018)
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Accurate detection of mosaic variants in sequencing data without matched controls
Dou, Yanmei, Kwon, Minseok, Rodin, Rachel E., Cortés-Ciriano, Isidro, Doan, Ryan, Luquette, Lovelace J., Galor, Alon, Bohrson, Craig, Walsh, Christopher A., Park, Peter J.
Published in Nature biotechnology (01.03.2020)
Published in Nature biotechnology (01.03.2020)
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Single-cell genome sequencing of human neurons identifies somatic point mutation and indel enrichment in regulatory elements
Luquette, Lovelace J., Miller, Michael B., Zhou, Zinan, Bohrson, Craig L., Zhao, Yifan, Jin, Hu, Gulhan, Doga, Ganz, Javier, Bizzotto, Sara, Kirkham, Samantha, Hochepied, Tino, Libert, Claude, Galor, Alon, Kim, Junho, Lodato, Michael A., Garaycoechea, Juan I., Gawad, Charles, West, Jay, Walsh, Christopher A., Park, Peter J.
Published in Nature genetics (01.10.2022)
Published in Nature genetics (01.10.2022)
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Linked-read analysis identifies mutations in single-cell DNA-sequencing data
Bohrson, Craig L., Barton, Alison R., Lodato, Michael A., Rodin, Rachel E., Luquette, Lovelace J., Viswanadham, Vinay V., Gulhan, Doga C., Cortés-Ciriano, Isidro, Sherman, Maxwell A., Kwon, Minseok, Coulter, Michael E., Galor, Alon, Walsh, Christopher A., Park, Peter J.
Published in Nature genetics (01.04.2019)
Published in Nature genetics (01.04.2019)
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ATM Kinase Is Required for Telomere Elongation in Mouse and Human Cells
Lee, Stella Suyong, Bohrson, Craig, Pike, Alexandra Mims, Wheelan, Sarah Jo, Greider, Carol Widney
Published in Cell reports (Cambridge) (24.11.2015)
Published in Cell reports (Cambridge) (24.11.2015)
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Contrasting somatic mutation patterns in aging human neurons and oligodendrocytes
Ganz, Javier, Luquette, Lovelace J., Bizzotto, Sara, Miller, Michael B., Zhou, Zinan, Bohrson, Craig L., Jin, Hu, Tran, Antuan V., Viswanadham, Vinayak V., McDonough, Gannon, Brown, Katherine, Chahine, Yasmine, Chhouk, Brian, Galor, Alon, Park, Peter J., Walsh, Christopher A.
Published in Cell (11.04.2024)
Published in Cell (11.04.2024)
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The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing
Rodin, Rachel E., Dou, Yanmei, Kwon, Minseok, Sherman, Maxwell A., D’Gama, Alissa M., Doan, Ryan N., Rento, Lariza M., Girskis, Kelly M., Bohrson, Craig L., Kim, Sonia N., Nadig, Ajay, Luquette, Lovelace J., Gulhan, Doga C., Park, Peter J., Walsh, Christopher A.
Published in Nature neuroscience (01.02.2021)
Published in Nature neuroscience (01.02.2021)
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Analysis of somatic mutations in 131 human brains reveals aging-associated hypermutability
Bae, Taejeong, Fasching, Liana, Wang, Yifan, Shin, Joo Heon, Suvakov, Milovan, Jang, Yeongjun, Norton, Scott, Dias, Caroline, Mariani, Jessica, Jourdon, Alexandre, Wu, Feinan, Panda, Arijit, Pattni, Reenal, Chahine, Yasmine, Yeh, Rebecca, Roberts, Rosalinda C, Huttner, Anita, Kleinman, Joel E, Hyde, Thomas M, Straub, Richard E, Walsh, Christopher A, Urban, Alexander E, Leckman, James F, Weinberger, Daniel R, Vaccarino, Flora M, Abyzov, Alexej
Published in Science (American Association for the Advancement of Science) (29.07.2022)
Published in Science (American Association for the Advancement of Science) (29.07.2022)
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Somatic mosaicism reveals clonal distributions of neocortical development
Breuss, Martin W., Yang, Xiaoxu, Schlachetzki, Johannes C. M., Antaki, Danny, Lana, Addison J., Xu, Xin, Chung, Changuk, Chai, Guoliang, Stanley, Valentina, Song, Qiong, Newmeyer, Traci F., Nguyen, An, O’Brien, Sydney, Hoeksema, Marten A., Cao, Beibei, Nott, Alexi, McEvoy-Venneri, Jennifer, Pasillas, Martina P., Barton, Scott T., Copeland, Brett R., Nahas, Shareef, Van Der Kraan, Lucitia, Ding, Yan, Glass, Christopher K., Gleeson, Joseph G.
Published in Nature (London) (28.04.2022)
Published in Nature (London) (28.04.2022)
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Control-independent mosaic single nucleotide variant detection with DeepMosaic
Yang, Xiaoxu, Xu, Xin, Breuss, Martin W., Antaki, Danny, Ball, Laurel L., Chung, Changuk, Shen, Jiawei, Li, Chen, George, Renee D., Wang, Yifan, Bae, Taejeong, Cheng, Yuhe, Abyzov, Alexej, Wei, Liping, Alexandrov, Ludmil B., Sebat, Jonathan L., Gleeson, Joseph G.
Published in Nature biotechnology (01.06.2023)
Published in Nature biotechnology (01.06.2023)
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Mapping recurrent mosaic copy number variation in human neurons
Sun, Chen, Kathuria, Kunal, Emery, Sarah B., Kim, ByungJun, Burbulis, Ian E., Shin, Joo Heon, Weinberger, Daniel R., Moran, John V., Kidd, Jeffrey M., Mills, Ryan E., McConnell, Michael J.
Published in Nature communications (17.05.2024)
Published in Nature communications (17.05.2024)
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Machine learning reveals bilateral distribution of somatic L1 insertions in human neurons and glia
Zhu, Xiaowei, Zhou, Bo, Pattni, Reenal, Gleason, Kelly, Tan, Chunfeng, Kalinowski, Agnieszka, Sloan, Steven, Fiston-Lavier, Anna-Sophie, Mariani, Jessica, Petrov, Dmitri, Barres, Ben A., Duncan, Laramie, Abyzov, Alexej, Vogel, Hannes, Moran, John V., Vaccarino, Flora M., Tamminga, Carol A., Levinson, Douglas F., Urban, Alexander E.
Published in Nature neuroscience (01.02.2021)
Published in Nature neuroscience (01.02.2021)
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Author Correction: Machine learning reveals bilateral distribution of somatic L1 insertions in human neurons and glia
Zhu, Xiaowei, Zhou, Bo, Pattni, Reenal, Gleason, Kelly, Tan, Chunfeng, Kalinowski, Agnieszka, Sloan, Steven, Fiston-Lavier, Anna-Sophie, Mariani, Jessica, Petrov, Dmitri, Barres, Ben A., Duncan, Laramie, Abyzov, Alexej, Vogel, Hannes, Moran, John V., Vaccarino, Flora M., Tamminga, Carol A., Levinson, Douglas F., Urban, Alexander E.
Published in Nature neuroscience (01.10.2023)
Published in Nature neuroscience (01.10.2023)
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Author Correction: The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing
Rodin, Rachel E., Dou, Yanmei, Kwon, Minseok, Sherman, Maxwell A., D’Gama, Alissa M., Doan, Ryan N., Rento, Lariza M., Girskis, Kelly M., Bohrson, Craig L., Kim, Sonia N., Nadig, Ajay, Luquette, Lovelace J., Gulhan, Doga C., Park, Peter J., Walsh, Christopher A.
Published in Nature neuroscience (01.10.2023)
Published in Nature neuroscience (01.10.2023)
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Abstract 5705: Mechanisms and therapeutic implications of hypermutation in gliomas
Touat, Mehdi, Li, Yvonne Y., Boynton, Adam N., Spurr, Liam F., Iorgulescu, Bryan, Bohrson, Craig L., Cortes-Ciriano, Isidro, Geduldig, Jack E., Pelton, Kristine, Lim-Fat, Mary J., Pal, Sangita, Ramkissoon, Shakti H., Dubois, Frank, Bellamy, Charlotte, Currimjee, Naomi, Qian, Kenin, Malinowski, Seth, Shetty, Aniket, Chow, Kin-Hoe, Verreault, Maïté, Guillerm, Erell, Ammari, Samy, Beuvon, Frédéric, Mokhtari, Karima, Alentorn, Agusti, Dehais, Caroline, Houillier, Caroline, Laigle-Donadey, Florence, Psimaras, Dimitri, Carpentier, Alexandre, Cornu, Philippe, Capelle, Laurent, Mathon, Bertrand, Barnholtz-Sloan, Jill S., Chakravarti, Arnab, Bi, Wenya L., Frampton, Garrett M., Sanson, Marc, Alexander, Brian M., Cherniack, Andrew, Wen, Patrick Y., Reardon, David A., Marabelle, Aurelien, Park, Peter J., Idbaih, Ahmed, Beroukhim, Rameen, Bandopadhayay, Pratiti, Bielle, Franck, Ligon, Keith L.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Abstract 4474: Functional characterization of alternatively spliced GSN in head and neck cancer
Kelley, Dylan Z., Flam, Emily L., Guo, Theresa, Bohrson, Craig, Considine, Michael, Danilova, Ludmila V., Bishop, Justin A., Zhang, Chi, Koch, Wayne M., Sidransky, David, Westra, William, Wheelan, Sarah, Florea, Liliana, Fertig, Elana J., Califano, Joseph A., Gaykalova, Daria A.
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Author Correction: The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing
Rodin, Rachel E., Dou, Yanmei, Kwon, Minseok, Sherman, Maxwell A., D’Gama, Alissa M., Doan, Ryan N., Rento, Lariza M., Girskis, Kelly M., Bohrson, Craig L., Kim, Sonia N., Nadig, Ajay, Luquette, Lovelace J., Gulhan, Doga C., Park, Peter J., Walsh, Christopher A.
Published in Nature neuroscience (01.04.2021)
Published in Nature neuroscience (01.04.2021)
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Functional characterization of alternatively spliced GSN in head and neck squamous cell carcinoma
Kelley, Dylan Z, Flam, Emily L, Guo, Theresa, Danilova, Ludmila V, Zamuner, Fernando T, Bohrson, Craig, Considine, Michael, Windsor, Eric J, Bishop, Justin A, Zhang, Chi, Koch, Wayne M, Sidransky, David, Westra, William H, Chung, Christine H, Califano, Joseph A, Wheelan, Sarah, Favorov, Alexander V, Florea, Liliana, Fertig, Elana J, Gaykalova, Daria A
Published in Translational research : the journal of laboratory and clinical medicine (01.12.2018)
Published in Translational research : the journal of laboratory and clinical medicine (01.12.2018)
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