A myelin-related transcriptomic profile is shared by Pitt–Hopkins syndrome models and human autism spectrum disorder
Phan, BaDoi N., Bohlen, Joseph F., Davis, Brittany A., Ye, Zengyou, Chen, Huei-Ying, Mayfield, Brent, Sripathy, Srinidhi Rao, Cerceo Page, Stephanie, Campbell, Morganne N., Smith, Hannah L., Gallop, Danisha, Kim, Hyojin, Thaxton, Courtney L., Simon, Jeremy M., Burke, Emily E., Shin, Joo Heon, Kennedy, Andrew J., Sweatt, J. David, Philpot, Benjamin D., Jaffe, Andrew E., Maher, Brady J.
Published in Nature neuroscience (01.03.2020)
Published in Nature neuroscience (01.03.2020)
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Molecular and Cellular Function of Transcription Factor 4 in Pitt-Hopkins Syndrome
Chen, Huei-Ying, Bohlen, Joseph F, Maher, Brady J
Published in Developmental neuroscience (01.09.2021)
Published in Developmental neuroscience (01.09.2021)
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Promyelinating drugs promote functional recovery in an autism spectrum disorder mouse model of Pitt–Hopkins syndrome
Bohlen, Joseph F, Cleary, Colin M, Das, Debamitra, Sripathy, Srinidhi Rao, Sadowski, Norah, Shim, Gina, Kenney, Rakaia F, Buchler, Ingrid P, Banerji, Tapasree, Scanlan, Thomas S, Mulkey, Daniel K, Maher, Brady J
Published in Brain (London, England : 1878) (01.08.2023)
Published in Brain (London, England : 1878) (01.08.2023)
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TCF4 Mutations Disrupt Synaptic Function Through Dysregulation of RIMBP2 in Patient-Derived Cortical Neurons
Davis, Brittany A., Chen, Huei-Ying, Ye, Zengyou, Ostlund, Isaac, Tippani, Madhavi, Das, Debamitra, Sripathy, Srinidhi Rao, Wang, Yanhong, Martin, Jacqueline M., Shim, Gina, Panchwagh, Neel M., Moses, Rebecca L., Farinelli, Federica, Bohlen, Joseph F., Li, Meijie, Luikart, Bryan W., Jaffe, Andrew E., Maher, Brady J.
Published in Biological psychiatry (1969) (01.04.2024)
Published in Biological psychiatry (1969) (01.04.2024)
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Psychiatric risk gene Transcription Factor 4 (TCF4) regulates the density and connectivity of distinct inhibitory interneuron subtypes
Chen, Huei-Ying, Phan, BaDoi N., Shim, Gina, Hamersky, Gregory R., Sadowski, Norah, O’Donnell, Thomas S., Sripathy, Srinidhi Rao, Bohlen, Joseph F., Pfenning, Andreas R., Maher, Brady J.
Published in Molecular psychiatry (01.11.2023)
Published in Molecular psychiatry (01.11.2023)
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Journal Article
TCF4 mutations disrupt synaptic function through dysregulation of RIMBP2 in patient-derived cortical neurons
Davis, Brittany A, Chen, Huei-Ying, Ye, Zengyou, Ostlund, Isaac, Tippani, Madhavi, Das, Debamitra, Srinidhi Rao Sripathy, Wang, Yanhong, Martin, Jacqueline M, Shim, Gina, Panchwagh, Neel M, Moses, Rebecca L, Farinelli, Federica, Bohlen, Joseph F, Li, Meijie, Luikart, Bryan W, Jaffe, Andrew E, Maher, Brady J
Published in bioRxiv (20.01.2023)
Published in bioRxiv (20.01.2023)
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A myelin-related transcriptomic profile is shared between Pitt Hopkins syndrome models and human autism spectrum disorder
Phan, BaDoi N., Bohlen, Joseph F., Davis, Brittany A., Ye, Zengyou, Chen, Huei-Ying, Mayfield, Brent, Sripathy, Srinidhi Rao, Page, Stephanie Cerceo, Campbell, Morganne N., Smith, Hannah L., Gallop, Danisha, Kim, Hyojin, Thaxton, Courtney L., Simon, Jeremy M., Burke, Emily E., Shin, Joo Heon, Kennedy, Andrew J., Sweatt, J. David, Philpot, Benjamin D., Jaffe, Andrew E., Maher, Brady J.
Published in Nature neuroscience (03.02.2020)
Published in Nature neuroscience (03.02.2020)
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Journal Article
TCF4 mutations disrupt synaptic function through dysregulation of RIMBP2 in patient-derived cortical neurons
Davis, Brittany A, Chen, Huei-Ying, Ye, Zengyou, Ostlund, Isaac, Tippani, Madhavi, Das, Debamitra, Sripathy, Srinidhi Rao, Wang, Yanhong, Martin, Jacqueline M, Shim, Gina, Panchwagh, Neel M, Moses, Rebecca L, Farinelli, Federica, Bohlen, Joseph F, Li, Meijie, Luikart, Bryan W, Jaffe, Andrew E, Maher, Brady J
Published in bioRxiv : the preprint server for biology (20.01.2023)
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Published in bioRxiv : the preprint server for biology (20.01.2023)
Journal Article
Clemastine fumarate enhances myelination and promotes functional recovery in a syndromic ASD mouse model of Pitt-Hopkins Syndrome
Bohlen, Joseph F, Cleary, Colin M, Das, Debamitra, Srinidhi Rao Sripathy, Sadowski, Norah L, Shim, Gina, Kenney, Rakaia F, Buchler, Ingrid P, Mulkey, Daniel K, Maher, Brady J
Published in bioRxiv (04.05.2022)
Published in bioRxiv (04.05.2022)
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Defects of myelination are common pathophysiology in syndromic and idiopathic autism spectrum disorders
Badoi Nguyen Phan, Page, Stephanie Cerceo, Campbell, Morganne N, Bohlen, Joseph F, Thaxton, Courtney L, Simon, Jeremy M, Burke, Emily E, Shin, Joo Heon, Kennedy, Andrew J, Sweatt, J David, Philpot, Benjamin D, Jaffe, Andrew E, Maher, Brady J
Published in bioRxiv (11.05.2017)
Published in bioRxiv (11.05.2017)
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