Targeting of interferon-beta to produce a specific, multi-mechanistic oncolytic vaccinia virus
Kirn, David H, Wang, Yaohe, Le Boeuf, Fabrice, Bell, John, Thorne, Steve H
Published in PLoS medicine (01.12.2007)
Published in PLoS medicine (01.12.2007)
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Oncolytic viruses sensitize human tumor cells for NY-ESO-1 tumor antigen recognition by CD4+ effector T cells
Delaunay, Tiphaine, Violland, Mathilde, Boisgerault, Nicolas, Dutoit, Soizic, Vignard, Virginie, Münz, Christian, Gannage, Monique, Dréno, Brigitte, Vaivode, Kristine, Pjanova, Dace, Labarrière, Nathalie, Wang, Yaohe, Chiocca, E. Antonio, Boeuf, Fabrice Le, Bell, John C., Erbs, Philippe, Tangy, Frédéric, Grégoire, Marc, Fonteneau, Jean-François
Published in Oncoimmunology (04.03.2018)
Published in Oncoimmunology (04.03.2018)
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A High-throughput Pharmacoviral Approach Identifies Novel Oncolytic Virus Sensitizers
Diallo, Jean-Simon, Boeuf, Fabrice Le, Lai, Frances, Cox, Julie, Vaha-Koskela, Markus, Abdelbary, Hesham, MacTavish, Heather, Waite, Katherine, Falls, Theresa, Wang, Jenny, Brown, Ryan, Blanchard, Jan E, Brown, Eric D, Kirn, David H, Hiscott, John, Atkins, Harry, Lichty, Brian D, Bell, John C
Published in Molecular therapy (01.06.2010)
Published in Molecular therapy (01.06.2010)
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Antiangiogenic Arming of an Oncolytic Vaccinia Virus Enhances Antitumor Efficacy in Renal Cell Cancer Models
Guse, Kilian, Sloniecka, Marta, Diaconu, Iulia, Ottolino-Perry, Kathryn, Tang, Nan, Ng, Calvin, Le Boeuf, Fabrice, Bell, John C, McCart, J Andrea, Ristimäki, Ari, Pesonen, Sari, Cerullo, Vincenzo, Hemminki, Akseli
Published in Journal of Virology (01.01.2010)
Published in Journal of Virology (01.01.2010)
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Resistance to Two Heterologous Neurotropic Oncolytic Viruses, Semliki Forest Virus and Vaccinia Virus, in Experimental Glioma
Vähä-Koskela, Markus J V, Le Boeuf, Fabrice, Lemay, Chantal, De Silva, Naomi, Diallo, Jean-Simon, Cox, Julie, Becker, Michelle, Choi, Youngmin, Ananth, Abhirami, Sellers, Clara, Breton, Sophie, Roy, Dominic, Falls, Theresa, Brun, Jan, Hemminki, Akseli, Hinkkanen, Ari, Bell, John C
Published in Journal of Virology (01.02.2013)
Published in Journal of Virology (01.02.2013)
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Multi-modal Potentiation of Oncolytic Virotherapy by Vanadium Compounds
Selman, Mohammed, Rousso, Christopher, Bergeron, Anabel, Son, Hwan Hee, Krishnan, Ramya, El-Sayes, Nader A., Varette, Oliver, Chen, Andrew, Le Boeuf, Fabrice, Tzelepis, Fanny, Bell, John C., Crans, Debbie C., Diallo, Jean-Simon
Published in Molecular therapy (03.01.2018)
Published in Molecular therapy (03.01.2018)
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Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity
Ilkow, Carolina S, Marguerie, Monique, Batenchuk, Cory, Mayer, Justin, Ben Neriah, Daniela, Cousineau, Sophie, Falls, Theresa, Jennings, Victoria A, Boileau, Meaghan, Bellamy, David, Bastin, Donald, de Souza, Christiano Tanese, Alkayyal, Almohanad, Zhang, Jiqing, Le Boeuf, Fabrice, Arulanandam, Rozanne, Stubbert, Lawton, Sampath, Padma, Thorne, Steve H, Paramanthan, Piriya, Chatterjee, Avijit, Strieter, Robert M, Burdick, Marie, Addison, Christina L, Stojdl, David F, Atkins, Harold L, Auer, Rebecca C, Diallo, Jean-Simon, Lichty, Brian D, Bell, John C
Published in Nature medicine (01.05.2015)
Published in Nature medicine (01.05.2015)
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The Oncolytic Poxvirus JX-594 Selectively Replicates in and Destroys Cancer Cells Driven by Genetic Pathways Commonly Activated in Cancers
Parato, Kelley A, Breitbach, Caroline J, Le Boeuf, Fabrice, Wang, Jiahu, Storbeck, Chris, Ilkow, Carolina, Diallo, Jean-Simon, Falls, Theresa, Burns, Joseph, Garcia, Vanessa, Kanji, Femina, Evgin, Laura, Hu, Kang, Paradis, Francois, Knowles, Shane, Hwang, Tae-Ho, Vanderhyden, Barbara C, Auer, Rebecca, Kirn, David H, Bell, John C
Published in Molecular therapy (01.04.2012)
Published in Molecular therapy (01.04.2012)
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Smac mimetics and innate immune stimuli synergize to promote tumor death
Beug, Shawn T, Tang, Vera A, LaCasse, Eric C, Cheung, Herman H, Beauregard, Caroline E, Brun, Jan, Nuyens, Jeffrey P, Earl, Nathalie, St-Jean, Martine, Holbrook, Janelle, Dastidar, Himika, Mahoney, Douglas J, Ilkow, Carolina, Le Boeuf, Fabrice, Bell, John C, Korneluk, Robert G
Published in Nature biotechnology (01.02.2014)
Published in Nature biotechnology (01.02.2014)
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Journal Article
Oncolytic Maraba Virus MG1 as a Treatment for Sarcoma
Le Boeuf, Fabrice, Selman, Mohammed, Son, Hwan Hee, Bergeron, Anabel, Chen, Andrew, Tsang, Jovian, Butterwick, Derek, Arulanandam, Rozanne, Forbes, Nicole E., Tzelepis, Fanny, Bell, John C., Werier, Joel, Abdelbary, Hesham, Diallo, Jean‐Simon
Published in International journal of cancer (15.09.2017)
Published in International journal of cancer (15.09.2017)
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Trial Watch: Oncolytic viro-immunotherapy of hematologic and solid tumors
Pol, Jonathan G., Lévesque, Sarah, Workenhe, Samuel T., Gujar, Shashi, Le Boeuf, Fabrice, Clements, Derek R., Fahrner, Jean-Eudes, Fend, Laetitia, Bell, John C., Mossman, Karen L., Fucikova, Jitka, Spisek, Radek, Zitvogel, Laurence, Kroemer, Guido, Galluzzi, Lorenzo
Published in Oncoimmunology (02.12.2018)
Published in Oncoimmunology (02.12.2018)
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Viral Delivery of CAR Targets to Solid Tumors Enables Effective Cell Therapy
Aalipour, Amin, Le Boeuf, Fabrice, Tang, Matthew, Murty, Surya, Simonetta, Federico, Lozano, Alexander X., Shaffer, Travis M., Bell, John C., Gambhir, Sanjiv S.
Published in Molecular therapy. Oncolytics (26.06.2020)
Published in Molecular therapy. Oncolytics (26.06.2020)
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Active-site mTOR inhibitors augment HSV1-dICP0 infection in cancer cells via dysregulated eIF4E/4E-BP axis
Zakaria, Chadi, Sean, Polen, Hoang, Huy-Dung, Leroux, Louis-Phillipe, Watson, Margaret, Workenhe, Samuel Tekeste, Hearnden, Jaclyn, Pearl, Dana, Truong, Vinh Tai, Robichaud, Nathaniel, Yanagiya, Akiko, Tahmasebi, Soroush, Jafarnejad, Seyed Mehdi, Jia, Jian-Jun, Pelin, Adrian, Diallo, Jean-Simon, Le Boeuf, Fabrice, Bell, John Cameron, Mossman, Karen Louise, Graber, Tyson Ernst, Jaramillo, Maritza, Sonenberg, Nahum, Alain, Tommy
Published in PLoS pathogens (23.08.2018)
Published in PLoS pathogens (23.08.2018)
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Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans
Breitbach, Caroline J., Burke, James, Jonker, Derek, Stephenson, Joe, Haas, Andrew R., Chow, Laura Q. M., Nieva, Jorge, Hwang, Tae-Ho, Moon, Anne, Patt, Richard, Pelusio, Adina, Le Boeuf, Fabrice, Burns, Joe, Evgin, Laura, De Silva, Naomi, Cvancic, Sara, Robertson, Terri, Je, Ji-Eun, Lee, Yeon-Sook, Parato, Kelley, Diallo, Jean-Simon, Fenster, Aaron, Daneshmand, Manijeh, Bell, John C., Kirn, David H.
Published in Nature (London) (01.09.2011)
Published in Nature (London) (01.09.2011)
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Regulation of Vascular Endothelial Growth Factor Receptor 2-mediated Phosphorylation of Focal Adhesion Kinase by Heat Shock Protein 90 and Src Kinase Activities
Le Boeuf, Fabrice, Houle, François, Huot, Jacques
Published in The Journal of biological chemistry (10.09.2004)
Published in The Journal of biological chemistry (10.09.2004)
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The importance of imaging strategies for pre-clinical and clinical in vivo distribution of oncolytic viruses
Pelin, Adrian, Wang, Jiahu, Bell, John, Le Boeuf, Fabrice
Published in Oncolytic virotherapy (01.01.2018)
Published in Oncolytic virotherapy (01.01.2018)
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Enhancement of vaccinia virus based oncolysis with histone deacetylase inhibitors
MacTavish, Heather, Diallo, Jean-Simon, Huang, Baocheng, Stanford, Marianne, Le Boeuf, Fabrice, De Silva, Naomi, Cox, Julie, Simmons, John Graydon, Guimond, Tanya, Falls, Theresa, McCart, J Andrea, Atkins, Harry, Breitbach, Caroline, Kirn, David, Thorne, Stephen, Bell, John C
Published in PloS one (30.12.2010)
Published in PloS one (30.12.2010)
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Deletion of Apoptosis Inhibitor F1L in Vaccinia Virus Increases Safety and Oncolysis for Cancer Therapy
Pelin, Adrian, Foloppe, Johann, Petryk, Julia, Singaravelu, Ragunath, Hussein, Marian, Gossart, Florian, Jennings, Victoria A., Stubbert, Lawton J., Foster, Madison, Storbeck, Christopher, Postigo, Antonio, Scut, Elena, Laight, Brian, Way, Michael, Erbs, Philippe, Le Boeuf, Fabrice, Bell, John C.
Published in Molecular therapy. Oncolytics (27.09.2019)
Published in Molecular therapy. Oncolytics (27.09.2019)
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Development and applications of oncolytic Maraba virus vaccines
Pol, Jonathan G, Atherton, Matthew J, Bridle, Byram W, Stephenson, Kyle B, Le Boeuf, Fabrice, Hummel, Jeff L, Martin, Chantal G, Pomoransky, Julia, Breitbach, Caroline J, Diallo, Jean-Simon, Stojdl, David F, Bell, John C, Wan, Yonghong, Lichty, Brian D
Published in Oncolytic virotherapy (01.01.2018)
Published in Oncolytic virotherapy (01.01.2018)
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