INT-1B3, an LNP formulated miR-193a-3p mimic, promotes anti-tumor immunity by enhancing T cell mediated immune responses via modulation of the tumor microenvironment and induction of immunogenic cell death
Duurland, Chantal L., Gunst, Thijs de, Boer, Harm C. den, Bosch, Marion T.J. van den, Telford, Bryony J., Vos, Rogier M., Xie, Xiaolei, Zang, Mingfa, Wang, Fang, Shao, Yingying, An, Xiaoyu, Wang, Jingjing, Cai, Jie, Bourré, Ludovic, Pinxteren, Laurens A.H. van, Schaapveld, Roel Q.J., Janicot, Michel, Yahyanejad, Sanaz
Published in Oncotarget (12.07.2024)
Published in Oncotarget (12.07.2024)
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Journal Article
Transcriptome-wide analysis reveals insight into tumor suppressor functions of 1B3, a novel synthetic miR-193a-3p mimic
van den Bosch, Marion T.J., Yahyanejad, Sanaz, Alemdehy, Mir Farshid, Telford, Bryony J., de Gunst, Thijs, den Boer, Harm C., Vos, Rogier M., Stegink, Marieke, van Pinxteren, Laurens A.H., Schaapveld, Roel Q.J., Janicot, Michel
Published in Molecular therapy. Nucleic acids (05.03.2021)
Published in Molecular therapy. Nucleic acids (05.03.2021)
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Journal Article
Multi-modal effects of 1B3, a novel synthetic miR-193a-3p mimic, support strong potential for therapeutic intervention in oncology
Telford, Bryony J, Yahyanejad, Sanaz, de Gunst, Thijs, den Boer, Harm C, Vos, Rogier M, Stegink, Marieke, van den Bosch, Marion T J, Alemdehy, Mir Farshid, van Pinxteren, Laurens A H, Schaapveld, Roel Q J, Janicot, Michel
Published in Oncotarget (02.03.2021)
Published in Oncotarget (02.03.2021)
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Journal Article
The tumor suppressor 5A2, a synthetic miR-7-5p mimic, targets oncogenic and metabolic pathways, as revealed by transcriptome-wide analysis
van den Bosch, Marion T. J., Telford, Bryony J., Yahyanejad, Sanaz, de Gunst, Thijs, den Boer, Harm C., Vos, Rogier M., Duurland, Chantal L., Biemans, Rianne, Dubois, Ludwig J., van Pinxteren, Laurens A. H., Schaapveld, Roel Q. J., Janicot, Michel
Published in Frontiers in drug discovery (07.07.2023)
Published in Frontiers in drug discovery (07.07.2023)
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