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Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability
Evrard, Solene M., Lecce, Laura, Michelis, Katherine C., Nomura-Kitabayashi, Aya, Pandey, Gaurav, Purushothaman, K-Raman, d’Escamard, Valentina, Li, Jennifer R., Hadri, Lahouaria, Fujitani, Kenji, Moreno, Pedro R., Benard, Ludovic, Rimmele, Pauline, Cohain, Ariella, Mecham, Brigham, Randolph, Gwendalyn J., Nabel, Elizabeth G., Hajjar, Roger, Fuster, Valentin, Boehm, Manfred, Kovacic, Jason C.
Published in Nature communications (24.06.2016)
Published in Nature communications (24.06.2016)
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Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease
Zhou, Qing, Wang, Hongying, Schwartz, Daniella M, Stoffels, Monique, Park, Yong Hwan, Zhang, Yuan, Yang, Dan, Demirkaya, Erkan, Takeuchi, Masaki, Tsai, Wanxia Li, Lyons, Jonathan J, Yu, Xiaomin, Ouyang, Claudia, Chen, Celeste, Chin, David T, Zaal, Kristien, Chandrasekharappa, Settara C, P Hanson, Eric, Yu, Zhen, Mullikin, James C, Hasni, Sarfaraz A, Wertz, Ingrid E, Ombrello, Amanda K, Stone, Deborah L, Hoffmann, Patrycja, Jones, Anne, Barham, Beverly K, Leavis, Helen L, van Royen-Kerkof, Annet, Sibley, Cailin, Batu, Ezgi D, Gül, Ahmet, Siegel, Richard M, Boehm, Manfred, Milner, Joshua D, Ozen, Seza, Gadina, Massimo, Chae, JaeJin, Laxer, Ronald M, Kastner, Daniel L, Aksentijevich, Ivona
Published in Nature genetics (01.01.2016)
Published in Nature genetics (01.01.2016)
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Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease
Zhou, Qing, Yu, Xiaomin, Demirkaya, Erkan, Deuitch, Natalie, Stone, Deborah, Tsai, Wanxia Li, Kuehn, Hye Sun, Wang, Hongying, Yang, Dan, Park, Yong Hwan, Ombrello, Amanda K., Blake, Mary, Romeo, Tina, Remmers, Elaine F., Chae, Jae Jin, Mullikin, James C., Güzel, Ferhat, Milner, Joshua D., Boehm, Manfred, Rosenzweig, Sergio D., Gadina, Massimo, Welch, Steven B., Özen, Seza, Topaloglu, Rezan, Abinun, Mario, Kastner, Daniel L., Aksentijevich, Ivona
Published in Proceedings of the National Academy of Sciences - PNAS (06.09.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (06.09.2016)
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CADASIL: new advances in basic science and clinical perspectives
Ferrante, Elisa A, Cudrici, Cornelia D, Boehm, Manfred
Published in Current opinion in hematology (01.05.2019)
Published in Current opinion in hematology (01.05.2019)
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p53 Regulates Mitochondrial Respiration
Matoba, Satoaki, Kang, Ju-Gyeong, Patino, Willmar D, Wragg, Andrew, Boehm, Manfred, Gavrilova, Oksana, Hurley, Paula J, Bunz, Fred, Hwang, Paul M
Published in Science (American Association for the Advancement of Science) (16.06.2006)
Published in Science (American Association for the Advancement of Science) (16.06.2006)
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In vivo transplantation of mammalian vascular organoids onto the chick chorioallantoic membrane reveals the formation of a hierarchical vascular network
Kowalski, William J., Vatti, Shravani, Sakamoto, Tyler, Li, Wenling, Odutola, Sarah Rose, Liu, Chengyu, Chen, Guibin, Boehm, Manfred, Mukouyama, Yoh-suke
Published in Scientific reports (28.02.2025)
Published in Scientific reports (28.02.2025)
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The Spectrum of the Deficiency of Adenosine Deaminase 2: An Observational Analysis of a 60 Patient Cohort
Barron, Karyl S., Aksentijevich, Ivona, Deuitch, Natalie T., Stone, Deborah L., Hoffmann, Patrycja, Videgar-Laird, Ryan, Soldatos, Ariane, Bergerson, Jenna, Toro, Camilo, Cudrici, Cornelia, Nehrebecky, Michele, Romeo, Tina, Jones, Anne, Boehm, Manfred, Kanakry, Jennifer A., Dimitrova, Dimana, Calvo, Katherine R., Alao, Hawwa, Kapuria, Devika, Ben-Yakov, Gil, Pichard, Dominique C., Hathaway, Londa, Brofferio, Alessandra, McRae, Elisa, Moura, Natalia Sampaio, Schnappauf, Oskar, Rosenzweig, Sofia, Heller, Theo, Cowen, Edward W., Kastner, Daniel L., Ombrello, Amanda K.
Published in Frontiers in immunology (10.01.2022)
Published in Frontiers in immunology (10.01.2022)
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Dysregulation of FOXO1 (Forkhead Box O1 Protein) Drives Calcification in Arterial Calcification due to Deficiency of CD73 and Is Present in Peripheral Artery Disease
Moorhead, William J., Chu, Claire C., Cuevas, Rolando A., Callahan, Jack, Wong, Ryan, Regan, Cailyn, Boufford, Camille K., Sur, Swastika, Liu, Mingjun, Gomez, Delphine, MacTaggart, Jason N., Kamenskiy, Alexey, Boehm, Manfred, St. Hilaire, Cynthia
Published in Arteriosclerosis, thrombosis, and vascular biology (01.07.2020)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.07.2020)
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Diminution of signal transducer and activator of transcription 3 signaling inhibits vascular permeability and anaphylaxis
Hox, Valerie, O'Connell, Michael P., Lyons, Jonathan J., Sackstein, Paul, Dimaggio, Thomas, Jones, Nina, Nelson, Celeste, Boehm, Manfred, Holland, Steven M., Freeman, Alexandra F., Tweardy, David J., Olivera, Ana, Metcalfe, Dean D., Milner, Joshua D.
Published in Journal of allergy and clinical immunology (01.07.2016)
Published in Journal of allergy and clinical immunology (01.07.2016)
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Circulating Blood Endothelial Nitric Oxide Synthase Contributes to the Regulation of Systemic Blood Pressure and Nitrite Homeostasis
Wood, Katherine C., Cortese-Krott, Miriam M., Kovacic, Jason C., Noguchi, Audrey, Liu, Virginia B., Wang, Xunde, Raghavachari, Nalini, Boehm, Manfred, Kato, Gregory J., Kelm, Malte, Gladwin, Mark T.
Published in Arteriosclerosis, thrombosis, and vascular biology (01.08.2013)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.08.2013)
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Increased activity of TNAP compensates for reduced adenosine production and promotes ectopic calcification in the genetic disease ACDC
Jin, Hui, St Hilaire, Cynthia, Huang, Yuting, Yang, Dan, Dmitrieva, Natalia I, Negro, Alejandra, Schwartzbeck, Robin, Liu, Yangtengyu, Yu, Zhen, Walts, Avram, Davaine, Jean-Michel, Lee, Duck-Yeon, Donahue, Danielle, Hsu, Kevin S, Chen, Jessica, Cheng, Tao, Gahl, William, Chen, Guibin, Boehm, Manfred
Published in Science signaling (13.12.2016)
Published in Science signaling (13.12.2016)
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Long-term engraftment and maturation of autologous iPSC-derived cardiomyocytes in two rhesus macaques
Lin, Yongshun, Sato, Noriko, Hong, Sogun, Nakamura, Kenta, Ferrante, Elisa A., Yu, Zu Xi, Chen, Marcus Y., Nakamura, Daisy S., Yang, Xiulan, Clevenger, Randall R., Hunt, Timothy J., Taylor, Joni L., Jeffries, Kenneth R., Keeran, Karen J., Neidig, Lauren E., Mehta, Atul, Schwartzbeck, Robin, Yu, Shiqin Judy, Kelly, Conor, Navarengom, Keron, Takeda, Kazuyo, Adler, Stephen S., Choyke, Peter L., Zou, Jizhong, Murry, Charles E., Boehm, Manfred, Dunbar, Cynthia E.
Published in Cell stem cell (05.07.2024)
Published in Cell stem cell (05.07.2024)
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Flavivirus Antagonism of Type I Interferon Signaling Reveals Prolidase as a Regulator of IFNAR1 Surface Expression
Lubick, Kirk J., Robertson, Shelly J., McNally, Kristin L., Freedman, Brett A., Rasmussen, Angela L., Taylor, R. Travis, Walts, Avram D., Tsuruda, Seitaro, Sakai, Mizuki, Ishizuka, Mariko, Boer, Elena F., Foster, Erin C., Chiramel, Abhilash I., Addison, Conrad B., Green, Richard, Kastner, Daniel L., Katze, Michael G., Holland, Steven M., Forlino, Antonella, Freeman, Alexandra F., Boehm, Manfred, Yoshii, Kentaro, Best, Sonja M.
Published in Cell host & microbe (08.07.2015)
Published in Cell host & microbe (08.07.2015)
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Human induced pluripotent stem cells (NIHTVBi029-A and NIHTVBi030-A) generated from two patients with a heterozygous mutation in the CDC42 gene
Varea, Isabella, Joseph, Benjamin, Emmerich, Kevin, Manohar-Sindhu, Sahana, Zou, Jizhong, Friend, Kip, Tang, Xuming, Yang, Dan, de Jesus Rasheed, Adriana A, Goldbach-Mansky, Raphaela, Boehm, Manfred
Published in Stem cell research (01.10.2024)
Published in Stem cell research (01.10.2024)
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Altered maturation and activation state of circulating monocytes is associated with their enhanced recruitment in pulmonary arterial hypertension
Harper, Rebecca L., Zhou, Xin, Marciano, David P., Cao, Aiqin, Wang, Lingli, Chen, Guibin, Adil, Mir S., Zhou, Wenyu, Maguire, Peter, Deivanayagam, Shanthi, Yu, Quan, Viswanathan, Vignesh, Yang, Dan, Martin, Marcy, Isobe, Sarasa, Otsuki, Shoichiro, Burgess, Jordan, Inglis, Audrey, Kelley, Devon, del Rosario, Patricia A., Hsi, Andrew, Haddad, Francois, Zamanian, Roham T., Boehm, Manfred, Snyder, Michael P., Rabinovitch, Marlene
Published in Respiratory research (15.04.2025)
Published in Respiratory research (15.04.2025)
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Robust generation of erythroid and multilineage hematopoietic progenitors from human iPSCs using a scalable monolayer culture system
Ruiz, Juan Pablo, Chen, Guibin, Haro Mora, Juan Jesus, Keyvanfar, Keyvan, Liu, Chengyu, Zou, Jizhong, Beers, Jeanette, Bloomer, Hanan, Qanash, Husam, Uchida, Naoya, Tisdale, John F., Boehm, Manfred, Larochelle, Andre
Published in Stem cell research (01.12.2019)
Published in Stem cell research (01.12.2019)
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Cardiomyocyte maturation: It takes a village to raise a kid
Negro, Alejandra, Boehm, Manfred
Published in Journal of molecular and cellular cardiology (01.09.2014)
Published in Journal of molecular and cellular cardiology (01.09.2014)
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Establishment of a human induced pluripotent stem cell line (NIHTVBi031-A) derived from a COPA syndrome patient with a heterozygous p.Ala239Pro mutation
Joseph, Benjamin, Varea, Isabella, Emmerich, Kevin, Manohar-Sindhu, Sahana, Zou, Jizhong, Friend, Kip, Sipwoli, Caleb, Tang, Xuming, Yang, Dan, de Jesus Rasheed, Adriana A, Goldbach-Mansky, Raphaela, Boehm, Manfred
Published in Stem cell research (01.10.2024)
Published in Stem cell research (01.10.2024)
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Mitochondrial Metabolism Modulates Differentiation and Teratoma Formation Capacity in Mouse Embryonic Stem Cells
Schieke, Stefan M., Ma, Mingchao, Cao, Liu, McCoy, J. Philip, Liu, Chengyu, Hensel, Nancy F., Barrett, A. John, Boehm, Manfred, Finkel, Toren
Published in The Journal of biological chemistry (17.10.2008)
Published in The Journal of biological chemistry (17.10.2008)
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