In vivo detection of Staphylococcus aureus endocarditis by targeting pathogen-specific prothrombin activation
Panizzi, Peter, Nahrendorf, Matthias, Figueiredo, Jose-Luiz, Panizzi, Jennifer, Marinelli, Brett, Iwamoto, Yoshiko, Keliher, Edmund, Maddur, Ashoka A, Waterman, Peter, Kroh, Heather K, Leuschner, Florian, Aikawa, Elena, Swirski, Filip K, Pittet, Mikael J, Hackeng, Tilman M, Fuentes-Prior, Pablo, Schneewind, Olaf, Bock, Paul E, Weissleder, Ralph
Published in Nature medicine (01.09.2011)
Published in Nature medicine (01.09.2011)
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Spatial distribution of factor Xa, thrombin, and fibrin(ogen) on thrombi at venous shear
Berny, Michelle A, Munnix, Imke C A, Auger, Jocelyn M, Schols, Saskia E M, Cosemans, Judith M E M, Panizzi, Peter, Bock, Paul E, Watson, Steve P, McCarty, Owen J T, Heemskerk, Johan W M
Published in PloS one (29.04.2010)
Published in PloS one (29.04.2010)
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Journal Article
Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation
Bode, Wolfram, Bock, Paul E, Friedrich, Rainer, Panizzi, Peter, Fuentes-Prior, Pablo, Richter, Klaus, Verhamme, Ingrid, Anderson, Patricia J, Kawabata, Shun-Ichiro, Huber, Robert
Published in Nature (02.10.2003)
Published in Nature (02.10.2003)
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Signal Recognition Particle Binds to Ribosome-bound Signal Sequences with Fluorescence-detected Subnanomolar Affinity That Does Not Diminish as the Nascent Chain Lengthens
Flanagan, John J, Chen, Jui-Chang, Miao, Yiwei, Shao, Yuanlong, Lin, Jialing, Bock, Paul E, Johnson, Arthur E
Published in The Journal of biological chemistry (16.05.2003)
Published in The Journal of biological chemistry (16.05.2003)
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Journal Article
Ratcheting of the Substrate from the Zymogen to Proteinase Conformations Directs the Sequential Cleavage of Prothrombin by Prothrombinase
Bianchini, Elsa P., Orcutt, Steven J., Panizzi, Peter, Bock, Paul E., Krishnaswamy, Sriram, Esmon, Charles T.
Published in Proceedings of the National Academy of Sciences - PNAS (19.07.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (19.07.2005)
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Restricted Active Site Docking by Enzyme-bound Substrate Enforces the Ordered Cleavage of Prothrombin by Prothrombinase
Hacisalihoglu, Ayse, Panizzi, Peter, Bock, Paul E., Camire, Rodney M., Krishnaswamy, Sriram
Published in The Journal of biological chemistry (09.11.2007)
Published in The Journal of biological chemistry (09.11.2007)
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Journal Article
Novel Fluorescent Prothrombin Analogs as Probes of Staphylocoagulase-Prothrombin Interactions
Panizzi, Peter, Friedrich, Rainer, Fuentes-Prior, Pablo, Kroh, Heather K., Briggs, Judy, Tans, Guido, Bode, Wolfram, Bock, Paul E.
Published in The Journal of biological chemistry (13.01.2006)
Published in The Journal of biological chemistry (13.01.2006)
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