A structural basis for how ligand binding site changes can allosterically regulate GPCR signaling and engender functional selectivity
Sanchez-Soto, Marta, Verma, Ravi Kumar, Willette, Blair K A, Gonye, Elizabeth C, Moore, Annah M, Moritz, Amy E, Boateng, Comfort A, Yano, Hideaki, Free, R Benjamin, Shi, Lei, Sibley, David R
Published in Science signaling (04.02.2020)
Published in Science signaling (04.02.2020)
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Functional and pharmacological role of the dopamine D4 receptor and its polymorphic variants
Ferré, Sergi, Belcher, Annabelle M., Bonaventura, Jordi, Quiroz, César, Sánchez-Soto, Marta, Casadó-Anguera, Verònica, Cai, Ning-Sheng, Moreno, Estefanía, Boateng, Comfort A., Keck, Thomas M., Florán, Benjamín, Earley, Christopher J., Ciruela, Francisco, Casadó, Vicent, Rubinstein, Marcelo, Volkow, Nora D.
Published in Frontiers in endocrinology (Lausanne) (30.09.2022)
Published in Frontiers in endocrinology (Lausanne) (30.09.2022)
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Benzothieno[3,2-b]quinolinium and 3-(phenylthio)quinolinium compounds: Synthesis and evaluation against opportunistic fungal pathogens
Boateng, Comfort A., Eyunni, Suresh V.K., Zhu, Xue Y., Etukala, Jagan R., Bricker, Barbara A., Ashfaq, M.K., Jacob, Melissa R., Khan, Shabana I., Walker, Larry A., Ablordeppey, Seth Y.
Published in Bioorganic & medicinal chemistry (01.01.2011)
Published in Bioorganic & medicinal chemistry (01.01.2011)
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Structure Activity Relationships for a Series of Eticlopride-Based Dopamine D-2/D-3 Receptor Bitopic Ligands
Shaik, Anver Basha, Boateng, Comfort A., Battiti, Francisco O., Bonifazi, Alessandro, Cao, Jianjing, Chen, Li, Chitsazi, Rezvan, Ravi, Saiprasad, Lee, Kuo Hao, Shi, Lei, Newman, Amy Hauck
Published in Journal of medicinal chemistry (28.10.2021)
Published in Journal of medicinal chemistry (28.10.2021)
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Development of Novel Tools for Dissection of Central Versus Peripheral Dopamine D2-Like Receptor Signaling in Dysglycemia
Bonifazi, Alessandro, Ellenberger, Michael, Farino, Zachary J., Aslanoglou, Despoina, Rais, Rana, Pereira, Sandra, Mantilla-Rivas, José O., Boateng, Comfort A., Eshleman, Amy J., Janowsky, Aaron, Hahn, Margaret K., Schwartz, Gary J., Slusher, Barbara S., Newman, Amy Hauck, Freyberg, Zachary
Published in Diabetes (New York, N.Y.) (01.09.2024)
Published in Diabetes (New York, N.Y.) (01.09.2024)
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Structure Activity Relationships for a Series of Eticlopride-Based Dopamine D2/D3 Receptor Bitopic Ligands
Shaik, Anver Basha, Boateng, Comfort A, Battiti, Francisco O, Bonifazi, Alessandro, Cao, Jianjing, Chen, Li, Chitsazi, Rezvan, Ravi, Saiprasad, Lee, Kuo Hao, Shi, Lei, Newman, Amy Hauck
Published in Journal of medicinal chemistry (28.10.2021)
Published in Journal of medicinal chemistry (28.10.2021)
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Toward Understanding the Structural Basis of Partial Agonism at the Dopamine D-3 Receptor
Michino, Mayako, Boateng, Comfort A., Donthamsetti, Prashant, Yano, Hideaki, Bakare, Oluyomi M., Bonifazi, Alessandro, Ellenberger, Michael P., Keck, Thomas M., Kumar, Vivek, Zhu, Clare, Verma, Ravi, Deschamps, Jeffrey R., Javitch, Jonathan A., Newman, Amy Hauck, Shi, Lei
Published in Journal of medicinal chemistry (26.01.2017)
Published in Journal of medicinal chemistry (26.01.2017)
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Journal Article
Toward Understanding the Structural Basis of Partial Agonism at the Dopamine D3 Receptor
Michino, Mayako, Boateng, Comfort A, Donthamsetti, Prashant, Yano, Hideaki, Bakare, Oluyomi M, Bonifazi, Alessandro, Ellenberger, Michael P, Keck, Thomas M, Kumar, Vivek, Zhu, Clare, Verma, Ravi, Deschamps, Jeffrey R, Javitch, Jonathan A, Newman, Amy Hauck, Shi, Lei
Published in Journal of medicinal chemistry (26.01.2017)
Published in Journal of medicinal chemistry (26.01.2017)
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Reflections of six neuroscientists: The influences of training at minority serving institutions
Grillo, Wendy, Boateng, Comfort A., Brady, Lillian J., Gaudier‐Diaz, Monica M., Mitchell, Kerry‐Ann, Ruffin, Vernon A., Tejdeda, Hugo A., Marshall, S. Alex
Published in Journal of neuroscience research (01.08.2022)
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Novel Dopamine D4 Receptor-Selective Antagonists For Neuropsychiatric Disorders
Keck, Thomas M, Kelshikar, Shreya, Shah, Nisha, McBride, Connor, Ximello Sanchez, Moises, Panasis, Diandra, Maslonka, Brianna, Muccilli, Abigail, Ladik, Maria, Akca, Ebrar, Ginet, Sophia, Nilson, Ashley, Boldizsar, Noelia, Free, R Benjamin, Sibley, David R, Boateng, Comfort A
Published in The FASEB journal (01.05.2022)
Published in The FASEB journal (01.05.2022)
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High Affinity Dopamine D3 Receptor (D3R)-Selective Antagonists Attenuate Heroin Self-Administration in Wild-Type but not D3R Knockout Mice
Boateng, Comfort A, Bakare, Oluyomi M, Zhan, Jia, Banala, Ashwini K, Burzynski, Caitlin, Pommier, Elie, Keck, Thomas M, Donthamsetti, Prashant, Javitch, Jonathan A, Rais, Rana, Slusher, Barbara S, Xi, Zheng-Xiong, Newman, Amy Hauck
Published in Journal of medicinal chemistry (13.08.2015)
Published in Journal of medicinal chemistry (13.08.2015)
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Dopamine D4 Receptor-Selective Compounds Reveal Structure–Activity Relationships that Engender Agonist Efficacy
Keck, Thomas M, Free, R. Benjamin, Day, Marilyn M, Brown, Sonvia L, Maddaluna, Michele S, Fountain, Griffin, Cooper, Charles, Fallon, Brooke, Holmes, Matthew, Stang, Christopher T, Burkhardt, Russell, Bonifazi, Alessandro, Ellenberger, Michael P, Newman, Amy H, Sibley, David R, Wu, Chun, Boateng, Comfort A
Published in Journal of medicinal chemistry (11.04.2019)
Published in Journal of medicinal chemistry (11.04.2019)
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Pharmacology and Therapeutic Potential of Benzothiazole Analogues for Cocaine Use Disorder
Boateng, Comfort A., Nilson, Ashley N., Placide, Rebekah, Pham, Mimi L., Jakobs, Franziska M., Boldizsar, Noelia, McIntosh, Scot, Stallings, Leia S., Korankyi, Ivana V., Kelshikar, Shreya, Shah, Nisha, Panasis, Diandra, Muccilli, Abigail, Ladik, Maria, Maslonka, Brianna, McBride, Connor, Sanchez, Moises Ximello, Akca, Ebrar, Alkhatib, Mohammad, Saez, Julianna, Nguyen, Catherine, Kurtyan, Emily, DePierro, Jacquelyn, Crowthers, Raymond, Brunt, Dylan, Bonifazi, Alessandro, Newman, Amy Hauck, Rais, Rana, Slusher, Barbara S., Free, R. Benjamin, Sibley, David R., Stewart, Kent D., Wu, Chun, Hemby, Scott E., Keck, Thomas M.
Published in Journal of medicinal chemistry (14.09.2023)
Published in Journal of medicinal chemistry (14.09.2023)
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Dopamine D-4 Receptor-Selective Compounds Reveal Structure-Activity Relationships that Engender Agonist Efficacy
Keck, Thomas M., Free, R. Benjamin, Day, Marilyn M., Brown, Sonvia L., Maddaluna, Michele S., Fountain, Griffin, Cooper, Charles, Fallon, Brooke, Holmes, Matthew, Stang, Christopher T., Burkhardt, Russell, Bonifazi, Alessandro, Ellenberger, Michael P., Newman, Amy H., Sibley, David R., Wu, Chun, Boateng, Comfort A.
Published in Journal of medicinal chemistry (11.04.2019)
Published in Journal of medicinal chemistry (11.04.2019)
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CoMFA studies and in vitro evaluation of some 3-substituted benzylthio quinolinium salts as anticryptococcal agents
Bolden, Sidney, Boateng, Comfort A., Zhu, Xue Y., Etukala, Jagan R., Eyunni, Suresh K., Jacob, Melissa R., Khan, Shabana I., Ablordeppey, Seth Y.
Published in Bioorganic & medicinal chemistry (15.11.2013)
Published in Bioorganic & medicinal chemistry (15.11.2013)
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Development of novel tools for dissection of central versus peripheral dopamine D 2 -like receptor signaling in dysglycemia
Bonifazi, Alessandro, Ellenberger, Michael, Farino, Zachary J, Aslanoglou, Despoina, Rais, Rana, Pereira, Sandra, Mantilla-Rivas, José O, Boateng, Comfort A, Eshleman, Amy J, Janowsky, Aaron, Hahn, Margaret K, Schwartz, Gary J, Slusher, Barbara S, Newman, Amy Hauck, Freyberg, Zachary
Published in bioRxiv : the preprint server for biology (24.02.2024)
Published in bioRxiv : the preprint server for biology (24.02.2024)
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Journal Article
High Affinity Dopamine D-3 Receptor (D3R)-Selective Antagonists Attenuate Heroin Self-Administration in Wild-Type but not D3R Knockout Mice
Boateng, Comfort A., Bakare, Oluyomi M., Zhan, Jia, Banala, Ashwini K., Burzynski, Caitlin, Pommier, Elie, Keck, Thomas M., Donthamsetti, Prashant, Javitch, Jonathan A., Rais, Rana, Slusher, Barbara S., Xi, Zheng-Xiong, Newman, Amy Hauck
Published in Journal of medicinal chemistry (13.08.2015)
Published in Journal of medicinal chemistry (13.08.2015)
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Journal Article
Towards understanding the structural basis of partial agonism at the dopamine D3 receptor
Michino, Mayako, Boateng, Comfort A., Donthamsetti, Prashant, Yano, Hideaki, Bakare, Oluyomi M., Bonifazi, Alessandro, Ellenberger, Michael P., Keck, Thomas M., Kumar, Vivek, Zhu, Clare, Verma, Ravi, Deschamps, Jeffrey R., Javitch, Jonathan A., Newman, Amy Hauck, Shi, Lei
Published in Journal of medicinal chemistry (05.01.2017)
Published in Journal of medicinal chemistry (05.01.2017)
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Journal Article
High Affinity Dopamine D 3 Receptor (D 3 R)-Selective Antagonists Attenuate Heroin Self-Administration in Wild-Type but not D 3 R Knockout Mice
Boateng, Comfort A., Bakare, Oluyomi M., Zhan, Jia, Banala, Ashwini K., Burzynski, Caitlin, Pommier, Elie, Keck, Thomas M., Donthamsetti, Prashant, Javitch, Jonathan A., Rais, Rana, Slusher, Barbara S., Xi, Zheng-Xiong, Newman, Amy Hauck
Published in Journal of medicinal chemistry (13.08.2015)
Published in Journal of medicinal chemistry (13.08.2015)
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Journal Article
Development of novel tools for dissection of central versus peripheral dopamine D2-like receptor signaling in dysglycemia
Bonifazi, Alessandro, Ellenberger, Michael, Farino, Zachary J, Aslanoglou, Despoina, Rais, Rana, Pereira, Sandra, Mantilla-Rivas, Jose O, Boateng, Comfort A, Eshleman, Amy J, Janowsky, Aaron, Hahn, Margaret K, Schwartz, Gary J, Slusher, Barbara S, Amy Hauck Newman, Freyberg, Zachary
Published in bioRxiv (24.02.2024)
Published in bioRxiv (24.02.2024)
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