Discovery of oxazole-based PDE4 inhibitors with picomolar potency
Kuang, Rongze, Shue, Ho-Jane, Xiao, Li, Blythin, David J., Shih, Neng-Yang, Chen, Xiao, Gu, Danlin, Schwerdt, John, Lin, Ling, Ting, Pauline C., Cao, Jianhua, Aslanian, Robert, Piwinski, John J., Prelusky, Daniel, Wu, Ping, Zhang, Ji, Zhang, Xiang, Celly, Chander S., Billah, Motasim, Wang, Peng
Published in Bioorganic & medicinal chemistry letters (01.04.2012)
Published in Bioorganic & medicinal chemistry letters (01.04.2012)
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Journal Article
Discovery of a highly potent series of oxazole-based phosphodiesterase 4 inhibitors
Kuang, Rongze, Shue, Ho-Jane, Blythin, David J., Shih, Neng-Yang, Gu, Danlin, Chen, Xiao, Schwerdt, John, Lin, Ling, Ting, Pauline C., Zhu, Xiaohong, Aslanian, Robert, Piwinski, John J., Xiao, Li, Prelusky, Daniel, Wu, Ping, Zhang, Ji, Zhang, Xiang, Celly, Chander S., Minnicozzi, Michael, Billah, Motasim, Wang, Peng
Published in Bioorganic & medicinal chemistry letters (15.09.2007)
Published in Bioorganic & medicinal chemistry letters (15.09.2007)
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Journal Article
Cyclic urea derivatives as potent NK1 selective antagonists
SHUE, Ho-Jane, XIAO CHEN, PIWINSKI, John J, DUFFY, Ruth A, LACHOWICZ, Jean E, COFFIN, Vicki L, FEI LIU, NOMEIR, Amin A, MORGAN, Cynthia A, VARTY, Geoffrey B, SHIH, Neng-Yang, BLYTHIN, David J, PALIWAL, Sunil, LING LIN, DANLIN GU, SCHWERDT, John H, SHAH, Sapna, REICHARD, Gregory A
Published in Bioorganic & medicinal chemistry letters (01.09.2005)
Published in Bioorganic & medicinal chemistry letters (01.09.2005)
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Journal Article
Cyclic urea derivatives as potent NK1 selective antagonists. Part II: Effects of fluoro and benzylic methyl substitutions
Shue, Ho-Jane, Chen, Xiao, Schwerdt, John H, Paliwal, Sunil, Blythin, David J, Lin, Ling, Gu, Danlin, Wang, Cheng, Reichard, Gregory A, Wang, Hongwu, Piwinski, John J, Duffy, Ruth A, Lachowicz, Jean E, Coffin, Vicki L, Nomeir, Amin A, Morgan, Cynthia A, Varty, Geoffrey B, Shih, Neng-Yang
Published in Bioorganic & medicinal chemistry letters (15.02.2006)
Published in Bioorganic & medicinal chemistry letters (15.02.2006)
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Journal Article
Synthesis and NK1/NK2 binding activities of a series of diacyl-substituted 2-arylpiperazines
BLYTHIN, David J, XIAO CHEN, PIWINSKI, John J, SHIH, Neng-Yang, SHUE, Ho-Jane, ANTHES, John C, MCPHAIL, Andrew T
Published in Bioorganic & medicinal chemistry letters (04.11.2002)
Published in Bioorganic & medicinal chemistry letters (04.11.2002)
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Journal Article
Antiinflammatory activity of substituted 6-hydroxypyrimido[2,1-f]purine-2,4,8(1H,3H,9H)-triones. Atypical nonsteroidal antiinflammatory agents
Blythin, David J, Kaminski, James J, Domalski, Martin S, Spitler, James, Solomon, Daniel M, Conn, David J, Wong, Shing Chun, Verbiar, Laura Lehman, Bober, Loretta A
Published in Journal of medicinal chemistry (01.06.1986)
Published in Journal of medicinal chemistry (01.06.1986)
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Journal Article
Biological evaluation and interconversion studies of rotamers of SCH 351125, an orally bioavailable CCR5 antagonist
Palani, Anandan, Shapiro, Sherry, Clader, John W., Greenlee, William J., Blythin, David, Cox, Kathleen, Wagner, Nicole E., Strizki, Julie, Baroudy, Bahige M., Dan, Niya
Published in Bioorganic & medicinal chemistry letters (24.02.2003)
Published in Bioorganic & medicinal chemistry letters (24.02.2003)
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Journal Article
Cyclic urea derivatives as potent NK sub(1) selective antagonists. Part II: Effects of fluoro and benzylic methyl substitutions
Shue, Ho-Jane, Chen, Xiao, Schwerdt, John H, Paliwal, Sunil, Blythin, David J, Lin, Ling, Gu, Danlin, Wang, Cheng, Reichard, Gregory A, Wang, Hongwu, Piwinski, John J, Duffy, Ruth A, Lachowicz, Jean E, Coffin, Vicki L, Nomeir, Amin A, Morgan, Cynthia A, Varty, Geoffrey B, Shih, Neng-Yang
Published in Bioorganic & medicinal chemistry letters (01.02.2006)
Published in Bioorganic & medicinal chemistry letters (01.02.2006)
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Journal Article
Cyclic urea derivatives as potent NK1 selective aantagonists. Part II: Effects of fluoro and benzylic methyl substitutions
SHUE, Ho-Jane, XIAO CHEN, PIWINSKI, John J, DULLY, Ruth A, LACHOWICZ, Jean E, COFFIN, Vicki L, NOMEIR, Amin A, MORGAN, Cynthia A, VARTY, Geoffrey B, SHIH, Neng-Yang, SCHWERDT, John H, PALIWAL, Sunil, BLYTHIN, David J, LING LIN, DANLIN GU, CHENG WANG, REICHARD, Gregory A, HONGWU WANG
Published in Bioorganic & medicinal chemistry letters (2006)
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Published in Bioorganic & medicinal chemistry letters (2006)
Journal Article
Cyclic urea derivatives as potent NK 1 selective antagonists. Part II: Effects of fluoro and benzylic methyl substitutions
Shue, Ho-Jane, Chen, Xiao, Schwerdt, John H., Paliwal, Sunil, Blythin, David J., Lin, Ling, Gu, Danlin, Wang, Cheng, Reichard, Gregory A., Wang, Hongwu, Piwinski, John J., Duffy, Ruth A., Lachowicz, Jean E., Coffin, Vicki L., Nomeir, Amin A., Morgan, Cynthia A., Varty, Geoffrey B., Shih, Neng-Yang
Published in Bioorganic & medicinal chemistry letters (2006)
Published in Bioorganic & medicinal chemistry letters (2006)
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Journal Article
Synthesis and NK(1)/NK(2) binding activities of a series of diacyl-substituted 2-arylpiperazines
Blythin, David J, Chen, Xiao, Piwinski, John J, Shih, Neng-Yang, Shue, Ho-Jane, Anthes, John C, McPhail, Andrew T
Published in Bioorganic & medicinal chemistry letters (04.11.2002)
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Published in Bioorganic & medicinal chemistry letters (04.11.2002)
Journal Article
Cyclic urea derivatives as potent NK 1 selective antagonists
Shue, Ho-Jane, Chen, Xiao, Shih, Neng-Yang, Blythin, David J., Paliwal, Sunil, Lin, Ling, Gu, Danlin, Schwerdt, John H., Shah, Sapna, Reichard, Gregory A., Piwinski, John J., Duffy, Ruth A., Lachowicz, Jean E., Coffin, Vicki L., Liu, Fei, Nomeir, Amin A., Morgan, Cynthia A., Varty, Geoffrey B.
Published in Bioorganic & medicinal chemistry letters (2005)
Published in Bioorganic & medicinal chemistry letters (2005)
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Journal Article
Synthesis and NK 1/NK 2 binding activities of a series of diacyl-substituted 2-arylpiperazines
Blythin, David J., Chen, Xiao, Piwinski, John J., Shih, Neng-Yang, Shue, Ho-Jane, Anthes, John C., McPhail, Andrew T.
Published in Bioorganic & medicinal chemistry letters (2002)
Published in Bioorganic & medicinal chemistry letters (2002)
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Journal Article
The morpholino-acetic acid analogue Sch 50911 is a selective GABA(B) receptor antagonist in rat neocortical slices
Ong, J, Marino, V, Parker, D A, Kerr, D I, Blythin, D J
Published in European journal of pharmacology (27.11.1998)
Published in European journal of pharmacology (27.11.1998)
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