Mechanically activated Piezo1 channels of cardiac fibroblasts stimulate p38 mitogen-activated protein kinase activity and interleukin-6 secretion
Blythe, Nicola M., Muraki, Katsuhiko, Ludlow, Melanie J., Stylianidis, Vasili, Gilbert, Hamish T.J., Evans, Elizabeth L., Cuthbertson, Kevin, Foster, Richard, Swift, Joe, Li, Jing, Drinkhill, Mark J., van Nieuwenhoven, Frans A., Porter, Karen E., Beech, David J., Turner, Neil A.
Published in The Journal of biological chemistry (15.11.2019)
Published in The Journal of biological chemistry (15.11.2019)
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Journal Article
Cardiac Fibroblast p38 MAPK: A Critical Regulator of Myocardial Remodeling
Turner, Neil A, Blythe, Nicola M
Published in Journal of cardiovascular development and disease (07.08.2019)
Published in Journal of cardiovascular development and disease (07.08.2019)
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Journal Article
Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels
Rubaiy, Hussein N., Ludlow, Melanie J., Henrot, Matthias, Gaunt, Hannah J., Miteva, Katarina, Cheung, Sin Ying, Tanahashi, Yasuyuki, Hamzah, Nurasyikin, Musialowski, Katie E., Blythe, Nicola M., Appleby, Hollie L., Bailey, Marc A., McKeown, Lynn, Taylor, Roger, Foster, Richard, Waldmann, Herbert, Nussbaumer, Peter, Christmann, Mathias, Bon, Robin S., Muraki, Katsuhiko, Beech, David J.
Published in The Journal of biological chemistry (19.05.2017)
Published in The Journal of biological chemistry (19.05.2017)
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Journal Article
Conservative management versus invasive management of significant traumatic pneumothoraces in the emergency department (the CoMiTED trial): a study protocol for a randomised non-inferiority trial
Blythe, Nicola M, Coates, Katherine, Benger, Jonathan R, Annaw, Ammar, Banks, Jonathan, Clement, Clare, Clout, Madeleine, Edwards, Antoinette, Gaunt, Daisy, Kandiyali, Rebecca, Lane, J Athene, Lecky, Fiona, Maskell, Nick A, Metcalfe, Chris, Platt, Marie, Rees, Sophie, Taylor, Jodi, Thompson, Julian, Walker, Steven, West, Douglas, Carlton, Edward
Published in BMJ open (17.06.2024)
Published in BMJ open (17.06.2024)
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Journal Article
Natural and synthetic flavonoid modulation of TRPC5 channels
Naylor, Jacqueline, Minard, Aisling, Gaunt, Hannah J, Amer, Mohamed S, Wilson, Lesley A, Migliore, Marco, Cheung, Sin Y, Rubaiy, Hussein N, Blythe, Nicola M, Musialowski, Katie E, Ludlow, Melanie J, Evans, William D, Green, Ben L, Yang, Hongjun, You, Yun, Li, Jing, Fishwick, Colin W G, Muraki, Katsuhiko, Beech, David J, Bon, Robin S
Published in British journal of pharmacology (01.02.2016)
Published in British journal of pharmacology (01.02.2016)
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Journal Article
Global PIEZO1 Gain-of-Function Mutation Causes Cardiac Hypertrophy and Fibrosis in Mice
Bartoli, Fiona, Evans, Elizabeth L, Blythe, Nicola M, Stewart, Leander, Chuntharpursat-Bon, Eulashini, Debant, Marjolaine, Musialowski, Katie E, Lichtenstein, Laeticia, Parsonage, Gregory, Futers, T Simon, Turner, Neil A, Beech, David J
Published in Cells (Basel, Switzerland) (02.04.2022)
Published in Cells (Basel, Switzerland) (02.04.2022)
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Journal Article
Yoda1 analogue (Dooku1) which antagonizes Yoda1‐evoked activation of Piezo1 and aortic relaxation
Evans, Elizabeth L, Cuthbertson, Kevin, Endesh, Naima, Rode, Baptiste, Blythe, Nicola M, Hyman, Adam J, Hall, Sally J, Gaunt, Hannah J, Ludlow, Melanie J, Foster, Richard, Beech, David J
Published in British journal of pharmacology (01.05.2018)
Published in British journal of pharmacology (01.05.2018)
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Journal Article
(−)-Englerin A-evoked Cytotoxicity Is Mediated by Na+ Influx and Counteracted by Na+/K+-ATPase
Ludlow, Melanie J., Gaunt, Hannah J., Rubaiy, Hussein N., Musialowski, Katie E., Blythe, Nicola M., Vasudev, Naveen S., Muraki, Katsuhiko, Beech, David J.
Published in The Journal of biological chemistry (13.01.2017)
Published in The Journal of biological chemistry (13.01.2017)
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Journal Article
P30 PIEZO1 – a role in cardiac fibroblast differentiation?
Blythe, Nicola M, Li, Jing, Drinkhill, Mark J, Beech, David J, Turner, Neil A
Published in Heart (British Cardiac Society) (01.10.2016)
Published in Heart (British Cardiac Society) (01.10.2016)
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Journal Article
Yoda1 analogue ( D ooku1) which antagonizes Y oda1‐evoked activation of P iezo1 and aortic relaxation
Evans, Elizabeth L, Cuthbertson, Kevin, Endesh, Naima, Rode, Baptiste, Blythe, Nicola M, Hyman, Adam J, Hall, Sally J, Gaunt, Hannah J, Ludlow, Melanie J, Foster, Richard, Beech, David J
Published in British journal of pharmacology (01.05.2018)
Published in British journal of pharmacology (01.05.2018)
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Journal Article
Stimulation of cardiac fibroblast Piezo1 channels opposes myofibroblast differentiation and induces IL-6 secretion via Ca2+-mediated p38 MAP kinase activation
Blythe, Nicola M, Stylianidis, Vasili, Ludlow, Melanie J, Gilbert, Hamish Tj, Evans, Elizabeth L, Cuthbertson, Kevin, Foster, Richard, Swift, Joe, Li, Jing, Drinkhill, Mark J, Van Nieuwenhoven, Frans A, Porter, Karen E, Beech, David J, Turner, Neil A
Published in bioRxiv (10.04.2019)
Published in bioRxiv (10.04.2019)
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