Redirecting an anti-IL-1β antibody to bind a new, unrelated and computationally predicted epitope on hIL-17A
Fischman, Sharon, Levin, Itay, Rondeau, Jean-Michel, Štrajbl, Marek, Lehmann, Sylvie, Huber, Thomas, Nimrod, Guy, Cebe, Régis, Omer, Dotan, Kovarik, Jiri, Bernstein, Shmuel, Sasson, Yehezkel, Demishtein, Alik, Shlamkovich, Tomer, Bluvshtein, Olga, Grossman, Noam, Barak-Fuchs, Reut, Zhenin, Michael, Fastman, Yair, Twito, Shir, Vana, Tal, Zur, Nevet, Ofran, Yanay
Published in Communications biology (29.09.2023)
Published in Communications biology (29.09.2023)
Get full text
Journal Article
704 The computationally designed human antibody, AU-007, mediates human immune activation by endogenous IL-2, while uniquely breaking the IL-2 auto-inhibitory loop and preventing Treg expansion
Amit, Inbar, Levin, Itay, Wyant, Timothy, Levitan, Natali, Barak, Reut, Ben-Mayor, May, Bluvshtein, Olga, Grossman, Noam, Sasson, Yehezkel, Nimrod, Guy, Zehnin, Michael, Fischman, Sharon, Štrajbl, Marek, Danielpur, Liron, Knickerbocker, Aron, Vasselli, James, Ofran, Yanay
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
Get full text
Journal Article
Characterization of BDG8: An antibody-human IL-2 complex that selectively activates the effector arm of the immune system
Wyant, Timothy, Amit, Inbar, Levin, Itay, Levitan, Natali, Grossman, Noam, Bluvshtein, Olga, Barak, Ruet, Nimrod, Guy, Fischman, Sharon, Strajbl, Marek, Sasson, Yehezkel, Zehnin, Michael, Ofran, Yanay
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
Get full text
Journal Article
ENGINEERED ANTI-IL-2 ANTIBODIES
Sharon FISCHMAN, Timothy WYANT, Yehezkel SASSON, Yanay OFRAN, Guy NIMROD, Noam GROSSMAN, Natalia LEVITIN, Itay LEVIN, Reut BARAK FUCHS, Inbar AMIT, Olga BLUVSHTEIN YERMOLAEV, Marek ŠTRAJBL, Michael ZHENIN
Year of Publication 07.12.2023
Get full text
Year of Publication 07.12.2023
Patent
DUAL BINDING ANTIBODIES, METHODS OF PRODUCING DUAL BINDING ANTIBODIES, AND USES THEREOF
OFRAN, Yanay, NIMROD, Guy, FISCHMAN, Sharon, DEMISHTEIN, ALIK, OMER, Dotan, BERNSTEIN, Schmuel, TWITO, Oshrat Shir, STRAJBL, Marek, FASTMAN, Yair, LEVIN, ltay, ZEHNIN, Michael, SASSON, Yehezkel, YERMOLAEV, Olga BLUVSHTEIN, FUCHS, Reut Barak
Year of Publication 28.03.2024
Get full text
Year of Publication 28.03.2024
Patent
ANTICORPOS ANTI-IL-2 MODIFICADOS
REUT BARAK FUCHS, SHARON FISCHMAN, OLGA BLUVSHTEIN YERMOLAEV, YANAY OFRAN, MICHAEL ZHENIN, YEHEZKEL SASSON, TIMOTHY WYANT, ITAY LEVIN, MAREK STRAJBL, GUY NIMROD, NOAM GROSSMAN, INBAR AMIT, NATALIA LEVITIN
Year of Publication 28.02.2023
Get full text
Year of Publication 28.02.2023
Patent
Anticorpos de ligação dupla manipulados e usos dos mesmos
REUT BARAK FUCHS, FASTMAN YAIR, OFRAN YANAY, DEMISHTEIN ALIK, OLGA BLUVSHTEIN YERMOLAEV, BERNSTEIN SHMUEL, DANIELPUR LIRON, IFRACH MORYA, FISCHMAN SHARON, NIMROD GUY, SHLAMKOVICH TOMER, SHNYDER ALEXEY, MALCHENKO NIKOL, SASSON YEHEZKEL, ZHENIN MICHAEL, CHEN AYELET, GATTEGNO HADAR, GROSSMAN NOAM, LEVIN ITAY, MEIR ITZHAK, STRAJBL MAREK
Year of Publication 20.02.2024
Get full text
Year of Publication 20.02.2024
Patent
ANTICORPOS ANTI-RECEPTOR DO FATOR DE NECROSE TUMORAL (TNFR2) E USOS DOS MESMOS
REUT BARAK FUCHS, SHARON FISCHMAN, OLGA BLUVSHTEIN YERMOLAEV, MICHAEL ZHENIN, YEHEZKEL SASSON, TIMOTHY WYANT, ITAY LEVIN, EFRAT CHOEN ZADA, MAY SOFIA BEN MAYOR, DOR SAMET, ALIK DEMISHTEIN, OSHRAT SHIR TWITO, NEVET ZUR BITON, YAIR FASTMAN, TAL VANA, AYELET CHEN, NINO OREN, MAREK STRAJBL, GUY NIMROD, NATALIE LEVITIN, NOAM GROSSMAN, INBAR AMIT, LIRON DANIELPUR
Year of Publication 31.01.2023
Get full text
Year of Publication 31.01.2023
Patent
ENGINEERED ANTI-IL-2 ANTIBODIES
OFRAN, Yanay, AMIT, Inbar, NIMROD, Guy, GROSSMAN, Noam, FISCHMAN, Sharon, LEVITIN, Natalia, BLUVSHTEIN YERMOLAEV, Olga, ZHENIN, Michael, STRAJBL, Marek, BARAK FUCHS, Reut, WYANT, Timothy, SASSON, Yehezkel, LEVIN, Itay
Year of Publication 21.03.2024
Get full text
Year of Publication 21.03.2024
Patent
Engineered anti-IL-2 antibodies
Grossman, Noam, Sasson, Yehezkel, Strajbl, Marek, Zhenin, Michael, Levitin, Natalia, Bluvshtein Yermolaev, Olga, Fischman, Sharon, Wyant, Timothy, Amit, Inbar, Levin, Itay, Nimrod, Guy, Barak Fuchs, Reut, Ofran, Yanay
Year of Publication 26.12.2023
Get full text
Year of Publication 26.12.2023
Patent
ENGINEERED ANTI-IL-2 ANTIBODIES
OFRAN, Yanay, AMIT, Inbar, NIMROD, Guy, GROSSMAN, Noam, FISCHMAN, Sharon, LEVITIN, Natalia, BLUVSHTEIN YERMOLAEV, Olga, ZHENIN, Michael, STRAJBL, Marek, BARAK FUCHS, Reut, WYANT, Timothy, SASSON, Yehezkel, LEVIN, Itay
Year of Publication 20.12.2023
Get full text
Year of Publication 20.12.2023
Patent
ENGINEERED ANTI-IL-2 ANTIBODIES
OFRAN, Yanay, AMIT, Inbar, NIMROD, Guy, GROSSMAN, Noam, FISCHMAN, Sharon, TRAJBL, Marek, LEVITIN, Natalia, BLUVSHTEIN YERMOLAEV, Olga, ZHENIN, Michael, BARAK FUCHS, Reut, WYANT, Timothy, SASSON, Yehezkel, LEVIN, Itay
Year of Publication 20.12.2023
Get full text
Year of Publication 20.12.2023
Patent
Engineered anti-IL-2 antibodies
ŠTRAJBL, Marek, OFRAN, Yanay, AMIT, Inbar, NIMROD, Guy, GROSSMAN, Noam, FISCHMAN, Sharon, LEVITIN, Natalia, BLUVSHTEIN YERMOLAEV, Olga, ZHENIN, Michael, BARAK FUCHS, Reut, WYANT, Timothy, SASSON, Yehezkel, LEVIN, Itay
Year of Publication 05.10.2023
Get full text
Year of Publication 05.10.2023
Patent
Engineered anti-il-2 antibodies
Grossman, Noam, Sasson, Yehezkel, Zhenin, Michael, Levitin, Natalia, Bluvshtein Yermolaev, Olga, Štrajbl, Marek, Fischman, Sharon, Wyant, Timothy, Amit, Inbar, Levin, Itay, Nimrod, Guy, Barak Fuchs, Reut, Ofran, Yanay
Year of Publication 25.08.2023
Get full text
Year of Publication 25.08.2023
Patent
ENGINEERED ANTI-IL-2 ANTIBODIES
OFRAN, Yanay, AMIT, Inbar, NIMROD, Guy, GROSSMAN, Noam, FISCHMAN, Sharon, LEVITIN, Natalia, BLUVSHTEIN YERMOLAEV, Olga, ZHENIN, Michael, STRAJBL, Marek, BARAK FUCHS, Reut, WYANT, Timothy, SASSON, Yehezkel, LEVIN, Itay
Year of Publication 29.06.2023
Get full text
Year of Publication 29.06.2023
Patent
ENGINEERED ANTI-IL-2 ANTIBODIES
OFRAN, Yanay, AMIT, Inbar, NIMROD, Guy, GROSSMAN, Noam, FISCHMAN, Sharon, LEVITIN, Natalia, BLUVSHTEIN YERMOLAEV, Olga, ZHENIN, Michael, STRAJBL, Marek, BARAK FUCHS, Reut, WYANT, Timothy, SASSON, Yehezkel, LEVIN, Itay
Year of Publication 16.03.2023
Get full text
Year of Publication 16.03.2023
Patent
DUAL BINDING ANTIBODIES, METHODS OF PRODUCING DUAL BINDING ANTIBODIES, AND USES THEREOF
OFRAN, Yanay, NIMROD, Guy, FISCHMAN, Sharon, OMER, Dotan, BLUVSHTEIN YERMOLAEV, Olga, ZHENIN, Michael, TWITO, Oshrat Shir, STRAJBL, Marek, DEMISHTEIN, Alik, BARAK FUCHS, Reut, FASTMAN, Yair, SASSON, Yehezkel, BERNSTEIN, Shmuel, LEVIN, Itay
Year of Publication 29.11.2023
Get full text
Year of Publication 29.11.2023
Patent
ENGINEERED ANTI-IL-2 ANTIBODIES
OFRAN, Yanay, AMIT, Inbar, NIMROD, Guy, GROSSMAN, Noam, FISCHMAN, Sharon, TRAJBL, Marek, LEVITIN, Natalia, BLUVSHTEIN YERMOLAEV, Olga, ZHENIN, Michael, BARAK FUCHS, Reut, WYANT, Timothy, SASSON, Yehezkel, LEVIN, Itay
Year of Publication 21.12.2022
Get full text
Year of Publication 21.12.2022
Patent
Engineered anti-IL-2 antibodies
ŠTRAJBL, Marek, OFRAN, Yanay, AMIT, Inbar, NIMROD, Guy, GROSSMAN, Noam, FISCHMAN, Sharon, LEVITIN, Natalia, BLUVSHTEIN YERMOLAEV, Olga, ZHENIN, Michael, BARAK FUCHS, Reut, WYANT, Timothy, SASSON, Yehezkel, LEVIN, Itay
Year of Publication 25.08.2022
Get full text
Year of Publication 25.08.2022
Patent
ENGINEERED DUAL BINDING ANTIBODIES AND USES THEREOF
OFRAN, Yanay, MALCHENKO, Nikol, NIMROD, Guy, GROSSMAN, Noam, SHLAMKOVICH, Tomer, FISCHMAN, Sharon, DANIELPUR, Liron, SHNYDER, Alexey, IFRACH, Morya, CHEN, Ayelet, BLUVSHTEIN YERMOLAEV, Olga, ZHENIN, Michael, STRAJBL, Marek, DEMISHTEIN, Alik, BARAK FUCHS, Reut, FASTMAN, Yair, SASSON, Yehezkel, BERNSTEIN, Shmuel, MEIR, Itzhak, LEVIN, Itay, GATTEGNO, Hadar
Year of Publication 17.04.2024
Get full text
Year of Publication 17.04.2024
Patent