Glioma-derived IL-33 orchestrates an inflammatory brain tumor microenvironment that accelerates glioma progression
De Boeck, Astrid, Ahn, Bo Young, D'Mello, Charlotte, Lun, Xueqing, Menon, Shyam V, Alshehri, Mana M, Szulzewsky, Frank, Shen, Yaoqing, Khan, Lubaba, Dang, Ngoc Ha, Reichardt, Elliott, Goring, Kimberly-Ann, King, Jennifer, Grisdale, Cameron J, Grinshtein, Natalie, Hambardzumyan, Dolores, Reilly, Karlyne M, Blough, Michael D, Cairncross, J Gregory, Yong, V Wee, Marra, Marco A, Jones, Steven J M, Kaplan, David R, McCoy, Kathy D, Holland, Eric C, Bose, Pinaki, Chan, Jennifer A, Robbins, Stephen M, Senger, Donna L
Published in Nature communications (05.10.2020)
Published in Nature communications (05.10.2020)
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Concurrent CIC mutations, IDH mutations, and 1p/19q loss distinguish oligodendrogliomas from other cancers
Yip, Stephen, Butterfield, Yaron S, Morozova, Olena, Chittaranjan, Suganthi, Blough, Michael D, An, Jianghong, Birol, Inanc, Chesnelong, Charles, Chiu, Readman, Chuah, Eric, Corbett, Richard, Docking, Rod, Firme, Marlo, Hirst, Martin, Jackman, Shaun, Karsan, Aly, Li, Haiyan, Louis, David N, Maslova, Alexandra, Moore, Richard, Moradian, Annie, Mungall, Karen L, Perizzolo, Marco, Qian, Jenny, Roldan, Gloria, Smith, Eric E, Tamura-Wells, Jessica, Thiessen, Nina, Varhol, Richard, Weiss, Samuel, Wu, Wei, Young, Sean, Zhao, Yongjun, Mungall, Andrew J, Jones, Steven JM, Morin, Gregg B, Chan, Jennifer A, Cairncross, J Gregory, Marra, Marco A
Published in The Journal of pathology (01.01.2012)
Published in The Journal of pathology (01.01.2012)
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Capicua regulates neural stem cell proliferation and lineage specification through control of Ets factors
Ahmad, Shiekh Tanveer, Rogers, Alexandra D, Chen, Myra J, Dixit, Rajiv, Adnani, Lata, Frankiw, Luke S, Lawn, Samuel O, Blough, Michael D, Alshehri, Mana, Wu, Wei, Marra, Marco A, Robbins, Stephen M, Cairncross, J Gregory, Schuurmans, Carol, Chan, Jennifer A
Published in Nature communications (01.05.2019)
Published in Nature communications (01.05.2019)
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Comprehensive genomic profiling of glioblastoma tumors, BTICs, and xenografts reveals stability and adaptation to growth environments
Shen, Yaoqing, Grisdale, Cameron J., Islam, Sumaiya A., Bose, Pinaki, Lever, Jake, Zhao, Eric Y., Grinshtein, Natalie, Ma, Yussanne, Mungall, Andrew J., Moore, Richard A., Lun, Xueqing, Senger, Donna L., Robbins, Stephen M., Wang, Alice Yijun, MacIsaac, Julia L., Kobor, Michael S., Luchman, H. Artee, Weiss, Samuel, Chan, Jennifer A., Blough, Michael D., Kaplan, David R., Cairncross, J. Gregory, Marra, Marco A., Jones, Steven J. M.
Published in Proceedings of the National Academy of Sciences - PNAS (17.09.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (17.09.2019)
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On-target JAK2/STAT3 inhibition slows disease progression in orthotopic xenografts of human glioblastoma brain tumor stem cells
Stechishin, Owen D, Luchman, H Artee, Ruan, Yibing, Blough, Michael D, Nguyen, Stephanie A, Kelly, John J, Cairncross, J Gregory, Weiss, Samuel
Published in Neuro-oncology (Charlottesville, Va.) (01.02.2013)
Published in Neuro-oncology (Charlottesville, Va.) (01.02.2013)
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ABT-888 restores sensitivity in temozolomide resistant glioma cells and xenografts
Yuan, Alice L, Ricks, Christian B, Bohm, Alexandra K, Lun, Xueqing, Maxwell, Lori, Safdar, Shahana, Bukhari, Shazreh, Gerber, Amanda, Sayeed, Wajid, Bering, Elizabeth A, Pedersen, Haley, Chan, Jennifer A, Shen, Yaoqing, Marra, Marco, Kaplan, David R, Mason, Warren, Goodman, Lindsey D, Ezhilarasan, Ravesanker, Kaufmann, Ascher B, Cabral, Matthew, Robbins, Steve M, Senger, Donna L, Cahill, Daniel P, Sulman, Erik P, Cairncross, J Gregory, Blough, Michael D
Published in PloS one (28.08.2018)
Published in PloS one (28.08.2018)
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Effect of aberrant p53 function on temozolomide sensitivity of glioma cell lines and brain tumor initiating cells from glioblastoma
Blough, Michael D., Beauchamp, Desiree C., Westgate, Morgan R., Kelly, John J., Cairncross, J. Gregory
Published in Journal of neuro-oncology (01.03.2011)
Published in Journal of neuro-oncology (01.03.2011)
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Mutations in CIC and IDH1 cooperatively regulate 2-hydroxyglutarate levels and cell clonogenicity
Chittaranjan, Suganthi, Chan, Susanna, Yang, Cindy, Yang, Kevin C, Chen, Vincent, Moradian, Annie, Firme, Marlo, Song, Jungeun, Go, Nancy E, Blough, Michael D, Chan, Jennifer A, Cairncross, J Gregory, Gorski, Sharon M, Morin, Gregg B, Yip, Stephen, Marra, Marco A
Published in Oncotarget (15.09.2014)
Published in Oncotarget (15.09.2014)
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p53 binding to the p21 promoter is dependent on the nature of DNA damage
Bodzak, Ewelina, Blough, Michael D., Lee, Patrick W.K., Hill, Richard
Published in Cell cycle (Georgetown, Tex.) (15.08.2008)
Published in Cell cycle (Georgetown, Tex.) (15.08.2008)
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Single-cell landscapes of primary glioblastomas and matched explants and cell lines show variable retention of inter- and intratumor heterogeneity
LeBlanc, Véronique G., Trinh, Diane L., Aslanpour, Shaghayegh, Hughes, Martha, Livingstone, Dorothea, Jin, Dan, Ahn, Bo Young, Blough, Michael D., Cairncross, J. Gregory, Chan, Jennifer A., Kelly, John J.P., Marra, Marco A.
Published in Cancer cell (11.04.2022)
Published in Cancer cell (11.04.2022)
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In the beginning: PDGFA and the genesis of GBM
Blough, Michael D, Kumar, Mehul, Bose, Pinaki, Cairncross, J Gregory
Published in Neuro-oncology (Charlottesville, Va.) (12.04.2021)
Published in Neuro-oncology (Charlottesville, Va.) (12.04.2021)
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Lactate dehydrogenase A silencing in IDH mutant gliomas
Chesnelong, Charles, Chaumeil, Myriam M, Blough, Michael D, Al-Najjar, Mohammad, Stechishin, Owen D, Chan, Jennifer A, Pieper, Russell O, Ronen, Sabrina M, Weiss, Samuel, Luchman, H Artee, Cairncross, J Gregory
Published in Neuro-oncology (Charlottesville, Va.) (01.05.2014)
Published in Neuro-oncology (Charlottesville, Va.) (01.05.2014)
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Mitogen-induced defective mitosis transforms neural progenitor cells
Omairi, Hiba K, Grisdale, Cameron J, Meode, Mathieu, Bohm, Alexandra K, Black, Sophie, Adam, Nancy J, Chapman, Cassidy P, Maroilley, Tatiana, Kelly, John J, Tarailo-Graovac, Maja, Jones, Steven J M, Blough, Michael D, Cairncross, John Gregory
Published in Neuro-oncology (Charlottesville, Va.) (03.10.2023)
Published in Neuro-oncology (Charlottesville, Va.) (03.10.2023)
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An in vivo patient-derived model of endogenous IDH1-mutant glioma
Luchman, H Artee, Stechishin, Owen D, Dang, N Ha, Blough, Michael D, Chesnelong, Charles, Kelly, John J, Nguyen, Stephanie A, Chan, Jennifer A, Weljie, Aalim M, Cairncross, J Gregory, Weiss, Samuel
Published in Neuro-oncology (Charlottesville, Va.) (01.02.2012)
Published in Neuro-oncology (Charlottesville, Va.) (01.02.2012)
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O6-methylguanine-DNA methyltransferase regulation by p53 in astrocytic cells
BLOUGH, Michael D, ZLATESCU, Magdalena C, CAIRNCROSS, J. Gregory
Published in Cancer research (Chicago, Ill.) (15.01.2007)
Published in Cancer research (Chicago, Ill.) (15.01.2007)
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PARP inhibition suppresses the emergence of temozolomide resistance in a model system
Yuan, Alice L., Meode, Mathieu, Tan, Melanie, Maxwell, Lori, Bering, Elizabeth. A., Pedersen, Haley, Willms, Jacob, Liao, Jenny, Black, Sophie, Cairncross, J. Gregory, Blough, Michael D.
Published in Journal of neuro-oncology (01.07.2020)
Published in Journal of neuro-oncology (01.07.2020)
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Hyperpolarized (13)C MR imaging detects no lactate production in mutant IDH1 gliomas: Implications for diagnosis and response monitoring
Chaumeil, Myriam M, Radoul, Marina, Najac, Chloé, Eriksson, Pia, Viswanath, Pavithra, Blough, Michael D, Chesnelong, Charles, Luchman, H Artee, Cairncross, J Gregory, Ronen, Sabrina M
Published in NeuroImage clinical (2016)
Published in NeuroImage clinical (2016)
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A novel C19MC amplified cell line links Lin28/let-7 to mTOR signaling in embryonal tumor with multilayered rosettes
Spence, Tara, Perotti, Christian, Sin-Chan, Patrick, Picard, Daniel, Wu, Wei, Singh, Anjali, Anderson, Colleen, Blough, Michael D, Cairncross, J Gregory, Lafay-Cousin, Lucie, Strother, Douglas, Hawkins, Cynthia, Narendran, Aru, Huang, Annie, Chan, Jennifer A
Published in Neuro-oncology (Charlottesville, Va.) (01.01.2014)
Published in Neuro-oncology (Charlottesville, Va.) (01.01.2014)
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Comparative genomic and genetic analysis of glioblastoma-derived brain tumor-initiating cells and their parent tumors
Davis, Brad, Shen, Yaoqing, Poon, Candice C, Luchman, H Artee, Stechishin, Owen D, Pontifex, Carly S, Wu, Wei, Kelly, John J, Blough, Michael D
Published in Neuro-oncology (Charlottesville, Va.) (01.03.2016)
Published in Neuro-oncology (Charlottesville, Va.) (01.03.2016)
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Small molecule epigenetic screen identifies novel EZH2 and HDAC inhibitors that target glioblastoma brain tumor-initiating cells
Grinshtein, Natalie, Rioseco, Constanza C, Marcellus, Richard, Uehling, David, Aman, Ahmed, Lun, Xueqing, Muto, Osamu, Podmore, Lauren, Lever, Jake, Shen, Yaoqing, Blough, Michael D, Cairncross, Greg J, Robbins, Stephen M, Jones, Steven J, Marra, Marco A, Al-Awar, Rima, Senger, Donna L, Kaplan, David R
Published in Oncotarget (13.09.2016)
Published in Oncotarget (13.09.2016)
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