The role of senescence, telomere dysfunction and shelterin in vascular aging
Liu, Yu, Bloom, Samuel I., Donato, Anthony J.
Published in Microcirculation (New York, N.Y. 1994) (01.02.2019)
Published in Microcirculation (New York, N.Y. 1994) (01.02.2019)
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Journal Article
Advanced age results in a diminished endothelial glycocalyx
Machin, Daniel R, Bloom, Samuel I, Campbell, Robert A, Phuong, Tam T T, Gates, Phillip E, Lesniewski, Lisa A, Rondina, Matthew T, Donato, Anthony J
Published in American journal of physiology. Heart and circulatory physiology (01.09.2018)
Published in American journal of physiology. Heart and circulatory physiology (01.09.2018)
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Journal Article
Mechanisms and consequences of endothelial cell senescence
Bloom, Samuel I, Islam, Md Torikul, Lesniewski, Lisa A, Donato, Anthony J
Published in Nature reviews cardiology (01.01.2023)
Published in Nature reviews cardiology (01.01.2023)
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Journal Article
A Focused DNA-Encoded Chemical Library for the Discovery of Inhibitors of NAD+‑Dependent Enzymes
Yuen, Lik Hang, Dana, Srikanta, Liu, Yu, Bloom, Samuel I, Thorsell, Ann-Gerd, Neri, Dario, Donato, Anthony J, Kireev, Dmitri, Schüler, Herwig, Franzini, Raphael M
Published in Journal of the American Chemical Society (03.04.2019)
Published in Journal of the American Chemical Society (03.04.2019)
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Journal Article
Endothelial cell telomere dysfunction induces senescence and results in vascular and metabolic impairments
Bloom, Samuel I., Liu, Yu, Tucker, Jordan R., Islam, Md Torikul, Machin, Daniel R., Abdeahad, Hossein, Thomas, Tyler G., Bramwell, R. Colton, Lesniewski, Lisa A., Donato, Anthony J.
Published in Aging cell (01.08.2023)
Published in Aging cell (01.08.2023)
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Journal Article
Mechanisms and consequences of endothelial cell senescence
Bloom, Samuel I., Islam, Md Torikul, Lesniewski, Lisa A., Donato, Anthony J.
Published in Nature reviews cardiology (19.07.2022)
Published in Nature reviews cardiology (19.07.2022)
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Journal Article
Endothelial-Specific Reduction in Arf6 Impairs Insulin-Stimulated Vasodilation and Skeletal Muscle Blood Flow Resulting in Systemic Insulin Resistance in Mice
Islam, Md Torikul, Cai, Jinjin, Allen, Shanena, Moreno, Denisse G, Bloom, Samuel I, Bramwell, R Colton, Mitton, Jonathan, Horn, Andrew G, Zhu, Weiquan, Donato, Anthony J, Holland, William L, Lesniewski, Lisa A
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2024)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2024)
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Journal Article
Endothelial cell‐specific reduction in mTOR ameliorates age‐related arterial and metabolic dysfunction
Islam, Md Torikul, Hall, Shelby A., Dutson, Tavia, Bloom, Samuel I., Bramwell, R. Colton, Kim, John, Tucker, Jordan R., Machin, Daniel R., Donato, Anthony J., Lesniewski, Lisa A.
Published in Aging cell (01.02.2024)
Published in Aging cell (01.02.2024)
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Journal Article
Correction to “A Focused DNA-Encoded Chemical Library for the Discovery of Inhibitors of NAD+‑Dependent Enzymes”
Yuen, Lik Hang, Dana, Srikanta, Liu, Yu, Bloom, Samuel I, Thorsell, Ann-Gerd, Neri, Dario, Donato, Anthony J, Kireev, Dmitri, Schüler, Herwig, Franzini, Raphael M
Published in Journal of the American Chemical Society (28.07.2021)
Published in Journal of the American Chemical Society (28.07.2021)
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Journal Article
T cells mediate cell non‐autonomous arterial ageing in mice
Trott, Daniel W., Machin, Daniel R., Phuong, Tam T. T., Adeyemo, AdeLola O., Bloom, Samuel I., Bramwell, R. Colton, Sorensen, Eric S., Lesniewski, Lisa A., Donato, Anthony J.
Published in The Journal of physiology (01.08.2021)
Published in The Journal of physiology (01.08.2021)
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Journal Article
Ablation of Endothelial mTOR is Benign in Young Mice and Reverses Age-Related Arterial and Metabolic Impairments in Old Mice
Islam, Md Torikul, Hall, Shelby A, Bloom, Samuel I, Bramwell, R Colton, Dutson, Tavia, Tucker, Jordan R, Kim, John, Machin, Daniel R, Donato, Anthony J, Lesniewski, Lisa A
Published in The FASEB journal (01.05.2022)
Published in The FASEB journal (01.05.2022)
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Journal Article
Aging results in endothelial cell telomere uncapping that induces senescence and physiological dysfunction
Bloom, Samuel I, Tucker, Jordan R, Liu, Yu, Abdeahad, Hossein, Machin, Daniel R, Thomas, Tyler G, Bramwell, R Colton, Islam, Md Torikul, Lesniewski, Lisa A, Donato, Anthony J
Published in The FASEB journal (01.05.2022)
Published in The FASEB journal (01.05.2022)
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Journal Article
Hemostatic Responses to Multiple Bouts of Firefighting Activity: Female vs. Male Differences in a High Demand, High Performance Occupation
Smith, Denise L, Horn, Gavin P, Petruzzello, Steven J, Freund, Gregory G, Bloom, Samuel I, Fernhall, Bo
Published in International journal of environmental research and public health (14.02.2022)
Published in International journal of environmental research and public health (14.02.2022)
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Journal Article
Reduction of double-strand DNA break repair exacerbates vascular aging
Bloom, Samuel I, Tucker, Jordan R, Machin, Daniel R, Abdeahad, Hossein, Adeyemo, AdeLola O, Thomas, Tyler G, Bramwell, R Colton, Lesniewski, Lisa A, Donato, Anthony J
Published in Aging (Albany, NY.) (02.10.2023)
Published in Aging (Albany, NY.) (02.10.2023)
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Journal Article
Induced Trf2 deletion leads to aging vascular phenotype in mice associated with arterial telomere uncapping, senescence signaling, and oxidative stress
Morgan, R. Garrett, Walker, Ashley E., Trott, Daniel W., Machin, Daniel R., Henson, Grant D., Reihl, Kelly D., Cawthon, Richard M., Denchi, Eros L., Liu, Yu, Bloom, Samuel I., Phuong, Tam T., Richardson, Russell S., Lesniewski, Lisa A., Donato, Anthony J.
Published in Journal of molecular and cellular cardiology (01.02.2019)
Published in Journal of molecular and cellular cardiology (01.02.2019)
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Journal Article
Firefighting Induces Acute Inflammatory Responses that are not Relieved by Aspirin in Older Firefighters
Smith, Denise L, Friedman, Nicholas M G, Bloom, Samuel I, Armero, William L, Pence, Brandt D, Cook, Marc D, Fernhall, Bo, Horn, Gavin P, Woods, Jeff
Published in Journal of occupational and environmental medicine (01.07.2019)
Published in Journal of occupational and environmental medicine (01.07.2019)
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Journal Article
Aging results in DNA damage and telomere dysfunction that is greater in endothelial versus vascular smooth muscle cells and is exacerbated in atheroprone regions
Bloom, Samuel I., Tucker, Jordan R., Lim, Jisok, Thomas, Tyler G., Stoddard, Gregory J., Lesniewski, Lisa A., Donato, Anthony J.
Published in GeroScience (01.12.2022)
Published in GeroScience (01.12.2022)
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Journal Article
Implications of endothelial shear stress on systemic sclerosis vasculopathy and treatment
Frech, Tracy M, Machin, Daniel R, Murtaugh, Maureen A, Stoddard, Gregory J, Bloom, Samuel I, Phibbs, Jessica V, Donato, Anthony J
Published in Clinical and experimental rheumatology (01.01.2018)
Published in Clinical and experimental rheumatology (01.01.2018)
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Journal Article