Deciphering the role of cDC2s in Sjögren’s syndrome: transcriptomic profile links altered antigen processes with IFN signature and autoimmunity
Lopes, Ana P, Hillen, Maarten R, Hinrichs, Anneline C, Blokland, Sofie LM, Bekker, Cornelis PJ, Pandit, Aridaman, Kruize, Aike A, Radstake, Timothy RDJ, van Roon, Joel A
Published in Annals of the rheumatic diseases (01.03.2023)
Published in Annals of the rheumatic diseases (01.03.2023)
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Journal Article
Increased CCL25 and T Helper Cells Expressing CCR9 in the Salivary Glands of Patients With Primary Sjögren's Syndrome: Potential New Axis in Lymphoid Neogenesis
Blokland, Sofie L. M., Hillen, Maarten R., Kruize, Aike A., Meller, Stephan, Homey, Bernhard, Smithson, Glennda M., Radstake, Timothy R. D. J., van Roon, Joel A. G.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.10.2017)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.10.2017)
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Epigenetically quantified immune cells in salivary glands of Sjögren’s syndrome patients: a novel tool that detects robust correlations of T follicular helper cells with immunopathology
Blokland, Sofie L M, van Vliet-Moret, Fréderique M, Hillen, Maarten R, Pandit, Aridaman, Goldschmeding, Roel, Kruize, Aike A, Bouma, Gerben, van Maurik, André, Olek, Sven, Hoffmueller, Ulrich, van Roon, Joel A G, Radstake, Timothy R D J
Published in Rheumatology (Oxford, England) (01.02.2020)
Published in Rheumatology (Oxford, England) (01.02.2020)
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Serum microRNA screening and functional studies reveal miR-483-5p as a potential driver of fibrosis in systemic sclerosis
Chouri, Eleni, Servaas, Nila H., Bekker, Cornelis P.J., Affandi, Alsya J., Cossu, Marta, Hillen, Maarten R., Angiolilli, Chiara, Mertens, Jorre S., van den Hoogen, Lucas L., Silva-Cardoso, Sandra, van der Kroef, Maarten, Vazirpanah, Nadia, Wichers, Catharina G.K., Carvalheiro, Tiago, Blokland, Sofie L.M., Giovannone, Barbara, Porretti, Laura, Marut, Wioleta, Vigone, Barbara, van Roon, Joel A.G., Beretta, Lorenzo, Rossato, Marzia, Radstake, Timothy R.D.J.
Published in Journal of autoimmunity (01.05.2018)
Published in Journal of autoimmunity (01.05.2018)
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Increased expression of Fas on group 2 and 3 innate lymphoid cells is associated with an interferon signature in systemic lupus erythematosus and Sjögren’s syndrome
Blokland, Sofie L M, van den Hoogen, Lucas L, Leijten, Emmerik F A, Hartgring, Sarita A Y, Fritsch, Ruth, Kruize, Aike A, van Roon, Joel A G, Radstake, Timothy R D J
Published in Rheumatology (Oxford, England) (01.10.2019)
Published in Rheumatology (Oxford, England) (01.10.2019)
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Journal Article
Cytometry by time of flight identifies distinct signatures in patients with systemic sclerosis, systemic lupus erythematosus and Sjögrens syndrome
Kroef, Maarten, Hoogen, Lucas L., Mertens, Jorre S., Blokland, Sofie L.M., Haskett, Scott, Devaprasad, Abhinandan, Carvalheiro, Tiago, Chouri, Eleni, Vazirpanah, Nadia, Cossu, Marta, Wichers, Catherina G.K, Silva‐Cardoso, Sandra C., Affandi, Alsya J., Bekker, Cornelis P.J., Lopes, Ana P., Hillen, Maarten R., Bonte‐Mineur, Femke, Kok, Marc R., Beretta, Lorenzo, Rossato, Marzia, Mingueneau, Michaël, Roon, Joel A.G., Radstake, Timothy R.D.J
Published in European journal of immunology (01.01.2020)
Published in European journal of immunology (01.01.2020)
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Dysregulated miRNome of plasmacytoid dendritic cells from patients with Sjögren’s syndrome is associated with processes at the centre of their function
Hillen, Maarten R, Chouri, Eleni, Wang, Maojie, Blokland, Sofie L M, Hartgring, Sarita A Y, Concepcion, Arno N, Kruize, Aike A, Burgering, Boudewijn M T, Rossato, Marzia, van Roon, Joel A G, Radstake, Timothy R D J
Published in Rheumatology (Oxford, England) (01.12.2019)
Published in Rheumatology (Oxford, England) (01.12.2019)
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Journal Article
Plasmacytoid DCs From Patients With Sjögren's Syndrome Are Transcriptionally Primed for Enhanced Pro-inflammatory Cytokine Production
Hillen, Maarten R, Pandit, Aridaman, Blokland, Sofie L M, Hartgring, Sarita A Y, Bekker, Cornelis P J, van der Heijden, Eefje H M, Servaas, Nila H, Rossato, Marzia, Kruize, Aike A, van Roon, Joel A G, Radstake, Timothy R D J
Published in Frontiers in immunology (04.09.2019)
Published in Frontiers in immunology (04.09.2019)
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The Transcriptomic Profile of Monocytes from Patients With Sjögren's Syndrome Is Associated With Inflammatory Parameters and Is Mimicked by Circulating Mediators
Lopes, Ana P, Bekker, Cornelis P J, Hillen, Maarten R, Blokland, Sofie L M, Hinrichs, Anneline C, Pandit, Aridaman, Kruize, Aike A, Radstake, Timothy R D J, van Roon, Joel A G
Published in Frontiers in immunology (03.08.2021)
Published in Frontiers in immunology (03.08.2021)
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Journal Article
Transcriptome Analysis of CCR9+ T Helper Cells From Primary Sjögren's Syndrome Patients Identifies CCL5 as a Novel Effector Molecule
Hinrichs, Anneline C, Blokland, Sofie L M, Lopes, Ana P, Wichers, Catharina G K, Kruize, Aike A, Pandit, Aridaman, Radstake, Timothy R D J, van Roon, Joel A G
Published in Frontiers in immunology (27.07.2021)
Published in Frontiers in immunology (27.07.2021)
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Journal Article
CCL5 Release by CCR9+ CD8 T Cells: A Potential Contributor to Immunopathology of Primary Sjögren’s Syndrome
Hinrichs, Anneline C., Blokland, Sofie L. M., Kruize, Aike A., Lafeber, Floris P. J., Leavis, Helen L., van Roon, Joel A. G.
Published in Frontiers in immunology (01.06.2022)
Published in Frontiers in immunology (01.06.2022)
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Journal Article
Autoantibodies to Cytosolic 5'-Nucleotidase 1A in Primary Sjögren's Syndrome and Systemic Lupus Erythematosus
Rietveld, Anke, van den Hoogen, Luuk L, Bizzaro, Nicola, Blokland, Sofie L M, Dähnrich, Cornelia, Gottenberg, Jacques-Eric, Houen, Gunnar, Johannsen, Nora, Mandl, Thomas, Meyer, Alain, Nielsen, Christoffer T, Olsson, Peter, van Roon, Joel, Schlumberger, Wolfgang, van Engelen, Baziel G M, Saris, Christiaan G J, Pruijn, Ger J M
Published in Frontiers in immunology (05.06.2018)
Published in Frontiers in immunology (05.06.2018)
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Journal Article
Circulating small non-coding RNAs reflect IFN status and B cell hyperactivity in patients with primary Sjögren's syndrome
Lopes, Ana P, Hillen, Maarten R, Chouri, Eleni, Blokland, Sofie L M, Bekker, Cornelis P J, Kruize, Aike A, Rossato, Marzia, van Roon, Joel A G, Radstake, Timothy R D J
Published in PloS one (15.02.2018)
Published in PloS one (15.02.2018)
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Journal Article
MicroRNA-130a Contributes to Type-2 Classical DC-activation in Sjögren's Syndrome by Targeting Mitogen- and Stress-Activated Protein Kinase-1
Lopes, Ana P, van Roon, Joel A G, Blokland, Sofie L M, Wang, Maojie, Chouri, Eleni, Hartgring, Sarita A Y, van der Wurff-Jacobs, Kim M G, Kruize, Aike A, Burgering, Boudewijn M T, Rossato, Marzia, Radstake, Timothy R D J, Hillen, Maarten R
Published in Frontiers in immunology (20.06.2019)
Published in Frontiers in immunology (20.06.2019)
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Journal Article
Leflunomide/hydroxychloroquine combination therapy targets type I IFN-associated proteins in patients with Sjögren’s syndrome that show potential to predict and monitor clinical response
Hamkour, Safae, van der Heijden, Eefje HM, Lopes, Ana P, Blokland, Sofie L M, Bekker, Cornelis P J, Van Helden-Meeuwsen, Cornelia G, Versnel, Marjan A, Kruize, Aike A, Radstake, Timothy RDJ, Leavis, Helen L, Hillen, Maarten R, van Roon, Joel AG
Published in Rheumatic & musculoskeletal diseases open (01.08.2023)
Published in Rheumatic & musculoskeletal diseases open (01.08.2023)
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Autoantigen TRIM21/Ro52 is expressed on the surface of antigen-presenting cells and its enhanced expression in Sjögren’s syndrome is associated with B cell hyperactivity and type I interferon activity
Hillen, Maarten R, Urso, Katia, Koppe, Emma, Lopes, Ana Pinheiro, Blokland, Sofie L M, Pandit, Aridaman, Slocombe, Tom, van Maurik, André, van Roon, Joel A G, Radstake, Timothy R D J
Published in Rheumatic & musculoskeletal diseases open (01.06.2020)
Published in Rheumatic & musculoskeletal diseases open (01.06.2020)
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Salivary gland secretome: a novel tool towards molecular stratification of patients with primary Sjögren’s syndrome and non-autoimmune sicca
Blokland, Sofie L M, Hillen, Maarten R, van Vliet-Moret, Fréderique M, Bikker, Angela, de Jager, Wilco, Pandit, Aridaman, Kruize, Aike A, Radstake, Timothy R D J, van Roon, Joel A G
Published in Rheumatic & musculoskeletal diseases open (01.01.2019)
Published in Rheumatic & musculoskeletal diseases open (01.01.2019)
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Journal Article
Increased mTORC1 activation in salivary gland B cells and T cells from patients with Sjögren’s syndrome: mTOR inhibition as a novel therapeutic strategy to halt immunopathology?
Blokland, Sofie L M, Hillen, Maarten R, Wichers, Catharina G K, Zimmermann, Maili, Kruize, Aike A, Radstake, Timothy R D J, Broen, Jasper C A, van Roon, Joel A G
Published in Rheumatic & musculoskeletal diseases open (01.01.2019)
Published in Rheumatic & musculoskeletal diseases open (01.01.2019)
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