Potassium leakage primes stored erythrocytes for phosphatidylserine exposure and shedding of pro‐coagulant vesicles
Burger, Patrick, Kostova, Elena, Bloem, Esther, Hilarius‐Stokman, Petra, Meijer, Alexander B., den Berg, Timo K., Verhoeven, Arthur J., Korte, Dirk, Bruggen, Robin
Published in British journal of haematology (01.02.2013)
Published in British journal of haematology (01.02.2013)
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Journal Article
von Willebrand factor binds to the surface of dendritic cells and modulates peptide presentation of factor VIII
Sorvillo, Nicoletta, Hartholt, Robin B, Bloem, Esther, Sedek, Magdalena, ten Brinke, Anja, van der Zwaan, Carmen, van Alphen, Floris P, Meijer, Alexander B, Voorberg, Jan
Published in Haematologica (Roma) (01.03.2016)
Published in Haematologica (Roma) (01.03.2016)
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Journal Article
Factor VIII/V C-domain swaps reveal discrete C-domain roles in factor VIII function and intracellular trafficking
Ebberink, Eduard H T M, Bouwens, Eveline A M, Bloem, Esther, Boon-Spijker, Mariëtte, van den Biggelaar, Maartje, Voorberg, Jan, Meijer, Alexander B, Mertens, Koen
Published in Haematologica (Roma) (01.04.2017)
Published in Haematologica (Roma) (01.04.2017)
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Journal Article
A3 Domain Region 1803–1818 Contributes to the Stability of Activated Factor VIII and Includes a Binding Site for Activated Factor IX
Bloem, Esther, Meems, Henriet, van den Biggelaar, Maartje, Mertens, Koen, Meijer, Alexander B.
Published in The Journal of biological chemistry (06.09.2013)
Published in The Journal of biological chemistry (06.09.2013)
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Journal Article
A novel next‐generation FVIIIa mimetic, Mim8, has a favorable safety profile and displays potent pharmacodynamic effects: Results from safety studies in cynomolgus monkeys
Lauritzen, Brian, Bjelke, Mads, Björkdahl, Olle, Bloem, Esther, Keane, Kevin, Kjalke, Marianne, Rossen, Marie, Lippert, Solvej Lund, Weldingh, Karin Nana, Skydsgaard, Mikala, Kjellev, Stine
Published in Journal of thrombosis and haemostasis (01.06.2022)
Published in Journal of thrombosis and haemostasis (01.06.2022)
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Journal Article
CTLA4‐Ig prevents development of neutralizing antibody formation after continuous treatment with human FVIII in HA rats
Øvlisen, Gabi Overgaard, Thygesen, Peter, Weldingh, Karin Nana, Bloem, Esther, Skov, Søren, Almholt, Kasper, Lövgren, Karin Maria, Ley, Carsten Dan, Holm, Thomas Lindebo
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.07.2022)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.07.2022)
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Journal Article
Factor VIII C1 Domain Spikes 2092–2093 and 2158–2159 Comprise Regions That Modulate Cofactor Function and Cellular Uptake
Bloem, Esther, van den Biggelaar, Maartje, Wroblewska, Aleksandra, Voorberg, Jan, Faber, Johan H., Kjalke, Marianne, Stennicke, Henning R., Mertens, Koen, Meijer, Alexander B.
Published in The Journal of biological chemistry (11.10.2013)
Published in The Journal of biological chemistry (11.10.2013)
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Journal Article
Kisspeptin-52 partially rescues the activity of the hypothalamus-pituitary-gonadal axis in underweight male rats dosed with an anti-obesity compound
Bolze, Florian, Williams, Hannah, Bhuwania, Ridhirama, Egecioglu, Emil, Bloem, Esther, Paulsson, Johan F., Pedersen, Marie Ø., Broadmeadow, Alan, Chesher, Clare J., Moore, Emma L., Skydsgaard, Mikala, Galle, Pia Søndergaard, Dalgaard, Majken, Wulff, Birgitte S., Tena-Sempere, Manuel, Andersen, Lærke W.
Published in Toxicology and applied pharmacology (01.10.2020)
Published in Toxicology and applied pharmacology (01.10.2020)
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Journal Article
Cellular uptake of coagulation factor VIII: Elusive role of the membrane-binding spikes in the C1 domain
Castro-Núñez, Lydia, Koornneef, Johanna M., Rondaij, Mariska G., Bloem, Esther, van der Zwaan, Carmen, Mertens, Koen, Meijer, Alexander B., Meems, Henriet
Published in The international journal of biochemistry & cell biology (01.08.2017)
Published in The international journal of biochemistry & cell biology (01.08.2017)
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Journal Article
Electrical resistivity tomography as monitoring tool for unsaturated zone transport: an example of preferential transport of deicing chemicals
Wehrer, Markus, Lissner, Heidi, Bloem, Esther, French, Helen, Totsche, Kai Uwe
Published in Environmental science and pollution research international (2014)
Published in Environmental science and pollution research international (2014)
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Journal Article
Mass Spectrometry-assisted Study Reveals That Lysine Residues 1967 and 1968 Have Opposite Contribution to Stability of Activated Factor VIII
Bloem, Esther, Meems, Henriet, van den Biggelaar, Maartje, van der Zwaan, Carmen, Mertens, Koen, Meijer, Alexander B.
Published in The Journal of biological chemistry (17.02.2012)
Published in The Journal of biological chemistry (17.02.2012)
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Journal Article
Factor VIII Region 1811–1818 Is Involved in Factor IXa Binding and Factor VIIIa Stability
Bloem, Esther, Meems, Henriet, van den Biggelaar, Maartje, Mertens, Koen, Meijer, Alexander B
Published in Blood (16.11.2012)
Published in Blood (16.11.2012)
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Journal Article
A novel chemical footprinting approach identifies critical lysine residues involved in the binding of receptor-associated protein to cluster II of LDL receptor-related protein
Bloem, Esther, Ebberink, Eduard H T M, van den Biggelaar, Maartje, van der Zwaan, Carmen, Mertens, Koen, Meijer, Alexander B
Published in Biochemical journal (15.05.2015)
Published in Biochemical journal (15.05.2015)
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Journal Article
Distinct Roles of Ser-764 and Lys-773 at the N Terminus of von Willebrand Factor in Complex Assembly with Coagulation Factor VIII
Castro-Núñez, Lydia, Bloem, Esther, Boon-Spijker, Mariëtte G., van der Zwaan, Carmen, van den Biggelaar, Maartje, Mertens, Koen, Meijer, Alexander B.
Published in The Journal of biological chemistry (04.01.2013)
Published in The Journal of biological chemistry (04.01.2013)
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Journal Article